SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fik'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_2
(DIHYDROFOLATE
REDUCTASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		3 / 3 TRP A 852
ARG A 903
THR A 851
 None
 0.87A 1df7A-6fikA:
undetectable		 1df7A-6fikA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4001_1
(SERUM ALBUMIN)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 9 LEU A 992
LEU A1233
VAL A1001
GLY A1000
LEU A1193
 None
 1.21A 1e7aB-6fikA:
undetectable		 1e7aB-6fikA:
9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H1D_A_SAMA301_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 ASN A 730
VAL A 731
GLY A 689
GLN A 664
HIS A 688
 None
 1.48A 1h1dA-6fikA:
undetectable		 1h1dA-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_B_NIOB702_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 5 PHE A 944
GLY A 934
THR A 984
PHE A 988
 None
 1.29A 1icvA-6fikA:
undetectable
1icvB-6fikA:
undetectable		 1icvA-6fikA:
16.74
1icvB-6fikA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG2_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 GLY A 121
GLY A  13
LEU A 339
THR A 124
ALA A 125
 None
 1.22A 1jg2A-6fikA:
undetectable		 1jg2A-6fikA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 ALA A 563
GLY A 504
VAL A 740
LEU A 743
LEU A 625
 None
 1.32A 1jipA-6fikA:
undetectable		 1jipA-6fikA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_2
(ADENOSINE KINASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 4 SER A1145
LEU A1017
TYR A1162
GLY A1008
 None
 1.38A 1liiA-6fikA:
undetectable		 1liiA-6fikA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 5 SER A 742
SER A 741
VAL A 731
PHE A 393
 None
 1.23A 1oipA-6fikA:
undetectable		 1oipA-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_A_ESTA1_1
(ESTROGEN RECEPTOR)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 10 LEU A 667
GLU A 699
LEU A 797
ILE A 645
HIS A 561
 None
 1.33A 1pcgA-6fikA:
undetectable		 1pcgA-6fikA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		3 / 3 GLU A 618
TRP A 444
LYS A 751
 None
 1.01A 1qu2A-6fikA:
undetectable		 1qu2A-6fikA:
6.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 8 LEU A 747
VAL A 621
GLY A 391
LEU A 743
 None
 0.97A 1s1xA-6fikA:
undetectable		 1s1xA-6fikA:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VID_A_SAMA301_0
(CATECHOL
O-METHYLTRANSFERASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 ASN A 730
VAL A 731
GLY A 689
GLN A 664
HIS A 688
 None
 1.48A 1vidA-6fikA:
undetectable		 1vidA-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_0
(VP39)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 GLN A 989
GLY A1012
VAL A1120
ALA A1036
LEU A1043
 None
 0.84A 1vptA-6fikA:
undetectable		 1vptA-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_0
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 GLY A 504
GLY A 579
GLY A 578
ASP A 550
SER A 555
 None
 1.15A 1wg8B-6fikA:
undetectable		 1wg8B-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 8 GLY A 504
THR A 808
ILE A 549
SER A 555
 None
 0.97A 2a8tB-6fikA:
undetectable		 2a8tB-6fikA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 LEU A  93
SER A 130
CYH A 306
ALA A 122
ALA A 119
 None
 1.12A 2bm9A-6fikA:
undetectable		 2bm9A-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_2
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		3 / 3 ALA A 127
THR A 144
PHE A  96
 None
 0.72A 2c6nB-6fikA:
undetectable		 2c6nB-6fikA:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_2
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		3 / 3 ALA A 454
THR A 838
PHE A 451
 None
 0.69A 2c6nB-6fikA:
undetectable		 2c6nB-6fikA:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A163_1
(BETA-LACTOGLOBULIN)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 VAL A 577
ILE A 384
LEU A 625
ILE A 642
ILE A 645
 None
 0.88A 2gj5A-6fikA:
undetectable		 2gj5A-6fikA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J0H_C_ACHC1289_0
(FICOLIN-2)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 4 ARG C1786
ASP C1787
THR C1783
LYS C1790
 None
 1.20A 2j0hC-6fikC:
undetectable		 2j0hC-6fikC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J0H_F_ACHF1289_0
(FICOLIN-2)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 4 ARG C1786
ASP C1787
THR C1783
LYS C1790
 None
 1.21A 2j0hF-6fikC:
undetectable		 2j0hF-6fikC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1290_1
(FICOLIN-2)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 4 ARG C1786
ASP C1787
THR C1783
LYS C1790
 None
 1.15A 2j2pF-6fikC:
undetectable		 2j2pF-6fikC:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQE_A_ADNA1002_1
(APRATAXIN AND
PNK-LIKE FACTOR)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 5 SER A 599
CYH A 615
TYR A 614
ARG A 616
 None
 1.44A 2kqeA-6fikA:
undetectable		 2kqeA-6fikA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		3 / 3 TYR A1271
GLY A 449
PHE A 451
 None
 0.71A 2m2pB-6fikA:
undetectable		 2m2pB-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_2
(NEURAMINIDASE A)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 6 ARG A 874
ASP A 636
ILE A 638
LEU A 628
 None
 1.03A 2ya7B-6fikA:
undetectable		 2ya7B-6fikA:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_2
(NEURAMINIDASE A)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 6 ARG A 874
ASP A 636
ILE A 638
LEU A 628
 None
 1.05A 2ya7D-6fikA:
undetectable		 2ya7D-6fikA:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_B_DP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 VAL A1171
PHE A1163
LEU A1031
ALA A1016
TYR A1162
 None
 1.32A 3apwB-6fikA:
undetectable		 3apwB-6fikA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWM_A_SAMA301_0
(CATECHOL
O-METHYLTRANSFERASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 ASN A 730
VAL A 731
GLY A 689
GLN A 664
HIS A 688
 None
 1.44A 3bwmA-6fikA:
undetectable		 3bwmA-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_1
(CYTOCHROME P450 2R1)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 VAL A1006
ALA A1005
VAL A1201
VAL A1022
ILE A1152
 None
 1.14A 3czhA-6fikA:
undetectable		 3czhA-6fikA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWV_A_RFXA801_1
(TRANSPORTER)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 LEU A1185
GLY A1184
LEU A1186
ILE A1144
ALA A1208
 None
 1.02A 3gwvA-6fikA:
undetectable		 3gwvA-6fikA:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWW_A_SFXA801_1
(TRANSPORTER)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 LEU A1185
GLY A1184
LEU A1186
ILE A1144
ALA A1208
 None
 1.00A 3gwwA-6fikA:
0.6		 3gwwA-6fikA:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_2
(GLUCOCORTICOID
RECEPTOR)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		3 / 3 MET A 966
CYH A 987
PRO A 961
 None
 1.17A 3h52C-6fikA:
undetectable		 3h52C-6fikA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_B_LEIB16_0
(COIL SER L16D-PEN)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 5 LEU A1038
GLN A1129
LEU A1127
GLU A1126
 None
 0.95A 3h5gA-6fikA:
undetectable
3h5gB-6fikA:
undetectable		 3h5gA-6fikA:
undetectable
3h5gB-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_C_LEIC16_0
(COIL SER L16D-PEN)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 6 LEU A1038
GLN A1129
LEU A1127
GLU A1126
 None
 0.92A 3h5gB-6fikA:
undetectable
3h5gC-6fikA:
undetectable		 3h5gB-6fikA:
undetectable
3h5gC-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_A_J3ZA2_1
(ESTROGEN RECEPTOR)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 LEU A  87
THR A  88
ALA A  91
LEU A  26
LEU A  27
 None
 1.14A 3hm1A-6fikA:
undetectable		 3hm1A-6fikA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		3 / 3 GLU A1207
GLY A1210
THR A1211
 None
 0.55A 3iazA-6fikA:
undetectable		 3iazA-6fikA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IXL_A_PACA5000_0
(ARYLMALONATE
DECARBOXYLASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 10 THR A 506
SER A 507
VAL A 620
GLY A 504
GLY A 579
 None
 1.40A 3ixlA-6fikA:
2.9		 3ixlA-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IXL_A_PACA5000_0
(ARYLMALONATE
DECARBOXYLASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 10 THR A 506
SER A 507
VAL A 620
SER A 736
GLY A 504
 None
 1.41A 3ixlA-6fikA:
2.9		 3ixlA-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_A_ACRA720_1
(ALPHA-AMYLASE, SUSG)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 7 GLU A1244
TRP A1245
LEU A1233
TRP A 996
 None
 1.00A 3k8mA-6fikA:
undetectable		 3k8mA-6fikA:
8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_B_ACRB820_1
(ALPHA-AMYLASE, SUSG)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 7 GLU A1244
TRP A1245
LEU A1233
TRP A 996
 None
 0.94A 3k8mB-6fikA:
undetectable		 3k8mB-6fikA:
8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 8 SER A 507
ASN A 581
ASN A 508
ASP A 467
 None
 1.27A 3n62A-6fikA:
undetectable		 3n62A-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		3 / 3 VAL A 276
VAL A 289
SER A 282
 None
 0.74A 3n8xB-6fikA:
undetectable		 3n8xB-6fikA:
9.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_C_ACTC4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 4 GLY A 695
GLY A 698
THR A 700
LEU A 769
 None
 0.89A 3si7C-6fikA:
undetectable
3si7D-6fikA:
undetectable		 3si7C-6fikA:
undetectable
3si7D-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_0
(GLYCINE
N-METHYLTRANSFERASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 6 SER A 493
HIS A 540
THR A 494
ARG A 490
 None
 1.36A 3thrB-6fikA:
undetectable		 3thrB-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_2
(PUTATIVE ADENOSINE
KINASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 5 LEU A 472
ALA A 619
THR A 476
PHE A 393
 None
 1.13A 3vasB-6fikA:
undetectable		 3vasB-6fikA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 LEU A 722
LEU A 707
ILE A 755
VAL A 671
GLU A 686
 None
 1.11A 3w1wB-6fikA:
3.1		 3w1wB-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		3 / 3 ASP A 634
LYS A 635
ASP A 636
 None
 0.77A 4a7tA-6fikA:
undetectable		 4a7tA-6fikA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB806_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 7 SER A 507
ASN A 581
ASN A 508
ASP A 467
 None
 1.30A 4kcnB-6fikA:
undetectable		 4kcnB-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_A_SAMA401_0
(METHYLTRANSFERASE
MPPJ)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 CYH A 553
GLY A 805
ILE A 656
ALA A 653
PHE A 801
 None
 1.08A 4kicA-6fikA:
undetectable		 4kicA-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_0
(METHYLTRANSFERASE
MPPJ)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 CYH A 553
GLY A 805
ILE A 656
ALA A 653
PHE A 801
 None
 1.06A 4kicB-6fikA:
undetectable		 4kicB-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 11 TRP A 996
ALA A 991
LEU A 992
GLY A1196
ALA A 833
 None
 1.22A 4l6v1-6fikA:
undetectable
4l6v6-6fikA:
undetectable		 4l6v1-6fikA:
7.76
4l6v6-6fikA:
25.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 9 TRP A 996
ALA A 991
LEU A 992
GLY A1196
ALA A 833
 None
 1.36A 4l6va-6fikA:
undetectable
4l6vf-6fikA:
undetectable		 4l6va-6fikA:
7.76
4l6vf-6fikA:
25.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_C_SAMC301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 ALA A 469
GLY A 578
GLY A 504
LEU A 560
ALA A 473
 None
 1.15A 4lg1C-6fikA:
undetectable		 4lg1C-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LS7_A_1X9A504_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 ALA A 552
CYH A 553
HIS A 688
THR A 690
HIS A 733
 None
 0.46A 4ls7A-6fikA:
44.1		 4ls7A-6fikA:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LS7_B_1X9B503_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 ALA A 552
CYH A 553
HIS A 688
THR A 690
HIS A 733
 None
 0.45A 4ls7A-6fikA:
44.1
4ls7B-6fikA:
43.9		 4ls7A-6fikA:
11.67
4ls7B-6fikA:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_B_MXMB606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 ILE A  90
VAL A  23
LEU A  87
ALA A  68
LEU A  39
 None
 1.01A 4m11B-6fikA:
undetectable		 4m11B-6fikA:
9.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 ILE A  90
VAL A  23
LEU A  87
ALA A  68
LEU A  39
 None
 1.05A 4m11C-6fikA:
undetectable		 4m11C-6fikA:
9.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_A_MRVA1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 7 GLN A 891
THR A 885
THR A1230
THR A 847
 None
 1.04A 4mbsA-6fikA:
undetectable		 4mbsA-6fikA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_2
(ADENOSINE KINASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 4 LEU A  26
SER A  24
LEU A  87
LEU A  95
 None
 0.87A 4n09A-6fikA:
undetectable		 4n09A-6fikA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 11 ILE A 831
ALA A 884
LEU A1233
ALA A1234
LEU A 864
 None
 1.03A 4nqaA-6fikA:
undetectable		 4nqaA-6fikA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		3 / 3 PRO A 354
LEU A 353
GLN A   6
 None
 0.66A 4pevB-6fikA:
undetectable		 4pevB-6fikA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 7 PHE A 941
MET A1229
THR A1230
LEU A1233
 None
 0.87A 5b1bN-6fikA:
undetectable
5b1bW-6fikA:
undetectable		 5b1bN-6fikA:
undetectable
5b1bW-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_F_MFXF2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 6 SER A1280
ASP A 593
ARG A 600
GLY A 440
 None
 0.97A 5cdqA-6fikA:
3.2
5cdqC-6fikA:
3.2
5cdqD-6fikA:
undetectable		 5cdqA-6fikA:
11.34
5cdqC-6fikA:
11.34
5cdqD-6fikA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_2_BEZ2801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 4 LEU A 772
ARG A 781
ILE A 779
ILE A 761
 None
 1.40A 5dzk2-6fikA:
undetectable
5dzkM-6fikA:
undetectable
5dzkN-6fikA:
undetectable		 5dzk2-6fikA:
undetectable
5dzkM-6fikA:
undetectable
5dzkN-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 5 THR A 647
ALA A 646
THR A 808
HIS A 561
 None
 1.27A 5ecmA-6fikA:
undetectable		 5ecmA-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 ASN A 730
VAL A 731
GLY A 689
GLN A 664
HIS A 688
 None
 1.48A 5fhrA-6fikA:
undetectable		 5fhrA-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 7 VAL A 740
SER A 741
ALA A 744
GLY A 391
 None
 0.65A 5fpdA-6fikA:
1.3		 5fpdA-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWZ_D_010D6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
PEDV MAIN PROTEASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		3 / 3 MET A 933
HIS A 985
GLY A1198
 None
 0.69A 5gwzB-6fikA:
undetectable		 5gwzB-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_H_SAMH301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 ALA A 288
GLN A  92
GLY A 117
THR A 124
SER A 284
 None
 1.41A 5hfjH-6fikA:
undetectable		 5hfjH-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI6_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 ALA A 389
LEU A 560
SER A 641
ILE A 384
LEU A 567
 None
 1.14A 5hi6A-6fikA:
undetectable		 5hi6A-6fikA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_C_IPHC101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 5 CYH A 809
ILE A 645
LEU A 667
HIS A 561
 None
 1.16A 5hrqC-6fikA:
undetectable
5hrqD-6fikA:
undetectable
5hrqL-6fikA:
undetectable		 5hrqC-6fikA:
undetectable
5hrqD-6fikA:
undetectable
5hrqL-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_E_FK5E201_1
(FK506-BINDING
PROTEIN 1)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 11 ASP A  37
VAL A 145
ILE A  90
ILE A  97
ILE A  34
 None
 1.21A 5hw8E-6fikA:
undetectable		 5hw8E-6fikA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGZ_A_SPRA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 9 LEU A 474
ILE A 532
GLU A 450
PHE A 451
GLU A 462
 None
 1.49A 5igzA-6fikA:
undetectable		 5igzA-6fikA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		3 / 3 VAL A1171
LEU A1043
MET A1113
 None
 0.81A 5ikrA-6fikA:
undetectable		 5ikrA-6fikA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K50_A_ACTA1403_0
(L-THREONINE
3-DEHYDROGENASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 5 SER A 741
VAL A 740
GLY A 579
ALA A 737
 None
 1.02A 5k50A-6fikA:
undetectable		 5k50A-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSA_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 ASN A 730
VAL A 731
GLY A 689
GLN A 664
HIS A 688
 None
 1.47A 5lsaA-6fikA:
undetectable		 5lsaA-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 TYR A 503
GLY A 504
VAL A 620
SER A 556
ALA A 563
 None
 1.10A 5n0oA-6fikA:
2.7		 5n0oA-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 TYR A 503
GLY A 504
VAL A 620
SER A 556
ALA A 563
 None
 1.11A 5n0oB-6fikA:
undetectable		 5n0oB-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		3 / 3 SER A1218
ALA A1217
THR A1202
 None
 0.53A 5n0xB-6fikA:
1.8		 5n0xB-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 9 ALA A 559
VAL A 577
ILE A 384
LEU A 625
ILE A 642
 None
 1.00A 5nunA-6fikA:
undetectable		 5nunA-6fikA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_MTLA805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 8 SER A 507
ASN A 581
ASN A 508
ASP A 467
 None
 1.28A 5vunA-6fikA:
undetectable		 5vunA-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 8 SER A 507
ASN A 581
ASN A 508
ASP A 467
 None
 1.31A 5vunB-6fikA:
undetectable		 5vunB-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 8 SER A 507
ASN A 581
ASN A 508
ASP A 467
 None
 1.31A 5vuoB-6fikA:
undetectable		 5vuoB-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 GLY A 732
GLY A 440
GLY A 617
GLU A 414
VAL A 427
 None
 0.83A 5wz1A-6fikA:
undetectable		 5wz1A-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 GLY A 732
GLY A 440
GLY A 617
GLU A 414
VAL A 427
 None
 0.83A 5wz1B-6fikA:
undetectable		 5wz1B-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 GLY A 732
GLY A 440
GLY A 617
GLU A 414
VAL A 427
 None
 0.86A 5wz1C-6fikA:
undetectable		 5wz1C-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 GLY A 732
GLY A 440
GLY A 617
GLU A 414
VAL A 427
 None
 0.81A 5wz1D-6fikA:
undetectable		 5wz1D-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 GLY A 732
GLY A 440
GLY A 617
GLU A 414
VAL A 427
 None
 0.87A 5wz1E-6fikA:
undetectable		 5wz1E-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 GLY A 732
GLY A 440
GLY A 617
GLU A 414
VAL A 427
 None
 0.82A 5wz1F-6fikA:
undetectable		 5wz1F-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 GLY A 732
GLY A 440
GLY A 617
GLU A 414
VAL A 427
 None
 0.83A 5wz1G-6fikA:
undetectable		 5wz1G-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 GLY A 732
GLY A 440
GLY A 617
GLU A 414
VAL A 427
 None
 0.85A 5wz1H-6fikA:
undetectable		 5wz1H-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA503_1
(CYTOCHROME P450 2C9)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 5 PRO A 545
GLY A 544
ASN A 497
LYS A 496
 None
 1.18A 5x23A-6fikA:
undetectable		 5x23A-6fikA:
8.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 GLU A 735
ARG A 616
TRP A 421
THR A 513
SER A1280
 None
 1.40A 5xiqB-6fikA:
4.7		 5xiqB-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_C_HFGC1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 GLU A 735
ARG A 616
TRP A 421
THR A 513
SER A1280
 None
 1.41A 5xiqC-6fikA:
undetectable		 5xiqC-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XU8_A_DX4A701_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 2)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 8 GLY A 442
CYH A 604
ASN A 603
PHE A 441
 None
 0.94A 5xu8A-6fikA:
undetectable		 5xu8A-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA502_1
(CYTOCHROME P450 2C9)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 6 PRO A 533
GLY A 534
ASN A 537
LYS A 541
 None
 0.90A 5xxiA-6fikA:
undetectable		 5xxiA-6fikA:
8.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		4 / 8 SER A 507
ASN A 581
ASN A 508
ASP A 467
 None
 1.34A 6auuB-6fikA:
undetectable		 6auuB-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3A_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 12 HIS A1116
GLY A1008
GLY A1012
ALA A1015
ILE A1144
 None
 1.15A 6b3aA-6fikA:
undetectable		 6b3aA-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_A_ACTA403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		3 / 3 TYR A 249
ASP A  14
GLN A  15
 None
 0.87A 6g1pA-6fikA:
undetectable		 6g1pA-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_A_FJQA501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 10 ALA A 575
ILE A 638
ALA A 640
ALA A 389
LEU A 387
 None
 1.09A 6h1lA-6fikA:
undetectable		 6h1lA-6fikA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_B_FJQB501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 6fik POLYKETIDE SYNTHASE
(Cercospora
nicotianae) 		5 / 11 ALA A 122
LEU A 123
VAL A 126
VAL A 147
THR A 144
 None
 1.00A 6h1lB-6fikA:
undetectable		 6h1lB-6fikA:
undetectable