SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fiv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_1
(PROTEIN (PROTEASE))		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 ARG A  13
LEU A  28
ASP A  30
ALA A  33
GLY A  58
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.63A 1c6yA-6fivA:
15.7		 1c6yA-6fivA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_2
(PROTEIN (PROTEASE))		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.30A 1c6yB-6fivA:
15.8		 1c6yB-6fivA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_1
(PROTEIN (PROTEASE))		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.31A 1c6zA-6fivA:
15.3		 1c6zA-6fivA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_2
(PROTEIN (PROTEASE))		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.53A 1c6zB-6fivA:
15.6		 1c6zB-6fivA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4S_A_TPVA201_1
(PROTEIN (HIV-1
PROTEASE))		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 LEU A  28
ASP A  30
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.41A 1d4sA-6fivA:
15.2		 1d4sA-6fivA:
29.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1D4Y_A_TPVA501_1
(PROTEIN (HIV-1
PROTEASE))		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 10 ARG A  13
LEU A  28
ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.59A 1d4yA-6fivA:
15.4		 1d4yA-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FB7_A_ROCA100_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.45A 1fb7A-6fivA:
15.7		 1fb7A-6fivA:
30.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G60_B_SAMB501_0
(ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  77
ILE A  18
THR A  82
MET A 107
ASN A 106
 None
 1.23A 1g60B-6fivA:
undetectable		 1g60B-6fivA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 ARG A  13
LEU A  28
ASP A  30
ALA A  33
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
None
 0.57A 1hsgA-6fivA:
15.4		 1hsgA-6fivA:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 LEU A  28
ASP A  30
ALA A  33
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.60A 1hsgA-6fivA:
15.4		 1hsgA-6fivA:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.42A 1hsgB-6fivA:
15.6		 1hsgB-6fivA:
29.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HSH_C_MK1C402_1
(HIV-II PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.26A 1hshC-6fivA:
16.3		 1hshC-6fivA:
31.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.25A 1hxbA-6fivA:
15.5		 1hxbA-6fivA:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_3
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ARG A  13
LEU A  28
ASP A  30
ALA A  33
GLY A  58
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.47A 1hxbB-6fivA:
15.5		 1hxbB-6fivA:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_3
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ARG A  13
LEU A  28
ASP A  30
ALA A  33
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
None
 0.59A 1hxbB-6fivA:
15.5		 1hxbB-6fivA:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 9 ASP A  30
GLY A  32
ASP A  34
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.62A 1hxwA-6fivA:
15.5		 1hxwA-6fivA:
28.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 11 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.52A 1hxwB-6fivA:
15.4		 1hxwB-6fivA:
28.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_2
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.60A 1k6cB-6fivA:
15.4		 1k6cB-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.30A 1muiA-6fivA:
15.7		 1muiA-6fivA:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OHR_A_1UNA201_1
(ASPARTYLPROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 11 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.49A 1ohrA-6fivA:
15.5		 1ohrA-6fivA:
29.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SDT_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.59A 1sdtB-6fivA:
15.5		 1sdtB-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SDU_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 LEU A  28
ASP A  30
ALA A  33
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.45A 1sduA-6fivA:
15.3		 1sduA-6fivA:
31.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SDU_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.32A 1sduB-6fivA:
15.5		 1sduB-6fivA:
31.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SDU_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.49A 1sduB-6fivA:
15.5		 1sduB-6fivA:
31.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SDV_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 ARG A  13
LEU A  28
ASP A  30
ALA A  33
GLY A  58
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.58A 1sdvA-6fivA:
15.6		 1sdvA-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SDV_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.31A 1sdvB-6fivA:
15.5		 1sdvB-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_2
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.46A 1sguB-6fivA:
15.7		 1sguB-6fivA:
29.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_2
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  37
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.48A 1sguB-6fivA:
15.7		 1sguB-6fivA:
29.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_1
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.46A 1t3rA-6fivA:
15.3		 1t3rA-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_1
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.22A 1t7iA-6fivA:
15.2		 1t7iA-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 10 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.56A 2aquA-6fivA:
15.5		 2aquA-6fivA:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 11 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.56A 2aquB-6fivA:
15.4		 2aquB-6fivA:
29.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AVS_B_MK1B902_1
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ARG A  13
LEU A  28
ASP A  30
GLY A  32
VAL A  59
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 0.55A 2avsA-6fivA:
15.2		 2avsA-6fivA:
31.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AVS_B_MK1B902_1
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  59
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 0.47A 2avsA-6fivA:
15.2		 2avsA-6fivA:
31.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AVS_B_MK1B902_3
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  59
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 0.41A 2avsB-6fivA:
15.3		 2avsB-6fivA:
31.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_1
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ARG A  13
LEU A  28
ASP A  30
GLY A  32
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
None
 0.61A 2avvA-6fivA:
15.3		 2avvA-6fivA:
29.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_1
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.22A 2avvA-6fivA:
15.3		 2avvA-6fivA:
29.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_1
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
None
 0.44A 2avvA-6fivA:
15.3		 2avvA-6fivA:
29.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_1
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
 0.48A 2avvD-6fivA:
15.3		 2avvD-6fivA:
29.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_1
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.22A 2avvD-6fivA:
15.3		 2avvD-6fivA:
29.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_3
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.33A 2avvE-6fivA:
15.5		 2avvE-6fivA:
29.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_3
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.48A 2avvE-6fivA:
15.5		 2avvE-6fivA:
29.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_1
(GAG-POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.24A 2b60A-6fivA:
15.8		 2b60A-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_1
(GAG-POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ASP A  34
ILE A  37
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.47A 2b60A-6fivA:
15.8		 2b60A-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_2
(GAG-POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 11 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.31A 2b60B-6fivA:
15.8		 2b60B-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B7Z_B_MK1B200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.24A 2b7zA-6fivA:
15.8		 2b7zA-6fivA:
27.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B7Z_B_MK1B200_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.41A 2b7zB-6fivA:
15.8		 2b7zB-6fivA:
27.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F80_B_017B301_1
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.22A 2f80A-6fivA:
15.5		 2f80A-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F80_B_017B301_2
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.19A 2f80B-6fivA:
15.6		 2f80B-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F80_B_017B301_2
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.41A 2f80B-6fivA:
15.6		 2f80B-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F81_A_017A302_1
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.19A 2f81A-6fivA:
15.5		 2f81A-6fivA:
31.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F81_A_017A302_1
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
None
 0.50A 2f81A-6fivA:
15.5		 2f81A-6fivA:
31.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F81_A_017A302_2
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.38A 2f81B-6fivA:
15.6		 2f81B-6fivA:
31.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F8G_B_017B401_1
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  59
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 0.22A 2f8gA-6fivA:
15.6		 2f8gA-6fivA:
31.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_1
(POL PROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 11 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.41A 2fxdA-6fivA:
15.3		 2fxdA-6fivA:
27.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_2
(POL PROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 7 ARG A  13
ASP A  30
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.33A 2fxdB-6fivA:
15.5		 2fxdB-6fivA:
27.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_2
(POL PROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 11 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.56A 2fxeB-6fivA:
15.5		 2fxeB-6fivA:
27.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HS1_A_017A201_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  37
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.35A 2hs1A-6fivA:
15.1		 2hs1A-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HS1_A_017A201_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ILE A  37
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.36A 2hs1B-6fivA:
15.6		 2hs1B-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HS1_A_017A201_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ILE A  37
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
None
 0.61A 2hs1B-6fivA:
15.6		 2hs1B-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.50A 2hs2A-6fivA:
15.0		 2hs2A-6fivA:
29.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.48A 2hs2B-6fivA:
15.6		 2hs2B-6fivA:
29.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IDW_B_017B401_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 9 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.28A 2idwB-6fivA:
15.3		 2idwB-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IEN_B_017B402_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.34A 2ienB-6fivA:
15.6		 2ienB-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IEO_A_017A402_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.19A 2ieoB-6fivA:
15.6		 2ieoB-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IEO_A_017A402_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.44A 2ieoB-6fivA:
15.6		 2ieoB-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NMY_A_ROCA401_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.35A 2nmyA-6fivA:
15.1		 2nmyA-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NMY_A_ROCA401_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.22A 2nmyB-6fivA:
15.2		 2nmyB-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NNK_A_ROCA401_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.41A 2nnkA-6fivA:
15.2		 2nnkA-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NNP_A_ROCA401_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 11 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.55A 2nnpA-6fivA:
15.1		 2nnpA-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NNP_A_ROCA401_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 ARG A  13
LEU A  28
ASP A  30
ALA A  33
GLY A  58
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.31A 2nnpB-6fivA:
15.3		 2nnpB-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NNP_A_ROCA401_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 ARG A  13
LEU A  28
ASP A  30
ALA A  33
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
None
 0.33A 2nnpB-6fivA:
15.3		 2nnpB-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2O4K_A_DR7A301_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
LEU A  28
ASP A  30
ALA A  33
ASP A  34
GLY A  58
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.29A 2o4kA-6fivA:
15.6		 2o4kA-6fivA:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2O4L_A_TPVA403_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 ARG A  13
LEU A  28
ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  59
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 0.52A 2o4lA-6fivA:
15.5		 2o4lA-6fivA:
31.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2O4L_A_TPVA403_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 ARG A  13
LEU A  28
ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.46A 2o4lA-6fivA:
15.5		 2o4lA-6fivA:
31.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2O4P_A_TPVA300_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 11 ARG A  13
LEU A  28
ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.56A 2o4pA-6fivA:
15.4		 2o4pA-6fivA:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2O4P_A_TPVA300_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 9 ARG A  13
LEU A  28
ASP A  30
ALA A  33
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.42A 2o4pB-6fivA:
15.5		 2o4pB-6fivA:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2O4S_A_AB1A400_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.63A 2o4sA-6fivA:
15.6		 2o4sA-6fivA:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2O4S_A_AB1A400_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.23A 2o4sB-6fivA:
15.5		 2o4sB-6fivA:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2O4S_A_AB1A400_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.58A 2o4sB-6fivA:
15.5		 2o4sB-6fivA:
30.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.38A 2pymA-6fivA:
15.5		 2pymA-6fivA:
28.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.40A 2pymB-6fivA:
15.5		 2pymB-6fivA:
28.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.42A 2pynA-6fivA:
15.8		 2pynA-6fivA:
27.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.42A 2pynB-6fivA:
15.8		 2pynB-6fivA:
27.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 9 ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.63A 2q5kA-6fivA:
15.0		 2q5kA-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.64A 2q5kB-6fivA:
15.4		 2q5kB-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.21A 2q5kB-6fivA:
15.4		 2q5kB-6fivA:
29.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q63_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.43A 2q63B-6fivA:
15.6		 2q63B-6fivA:
30.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_1
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.19A 2q64A-6fivA:
15.5		 2q64A-6fivA:
27.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QAK_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.18A 2qakB-6fivA:
15.6		 2qakB-6fivA:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QAK_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
None
 0.39A 2qakB-6fivA:
15.6		 2qakB-6fivA:
30.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_1
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 11 ARG A  13
ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.72A 2qhcA-6fivA:
15.3		 2qhcA-6fivA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_2
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.28A 2qhcB-6fivA:
15.4		 2qhcB-6fivA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_2
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.43A 2qhcB-6fivA:
15.4		 2qhcB-6fivA:
29.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2R5Q_B_1UNB900_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 11 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.46A 2r5qB-6fivA:
15.7		 2r5qB-6fivA:
31.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2R5Q_D_1UND900_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.28A 2r5qD-6fivA:
15.7		 2r5qD-6fivA:
31.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_1
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  37
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.39A 2rkfA-6fivA:
15.6		 2rkfA-6fivA:
28.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_2
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  37
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.39A 2rkgB-6fivA:
15.9		 2rkgB-6fivA:
28.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.21A 2z54A-6fivA:
15.4		 2z54A-6fivA:
27.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CYW_A_017A201_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.37A 3cywA-6fivA:
15.4		 3cywA-6fivA:
30.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CYW_A_017A201_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.53A 3cywA-6fivA:
15.4		 3cywA-6fivA:
30.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CYW_A_017A201_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.25A 3cywB-6fivA:
15.6		 3cywB-6fivA:
30.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CYW_A_017A201_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.51A 3cywB-6fivA:
15.6		 3cywB-6fivA:
30.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CYX_A_ROCA201_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  59
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 0.36A 3cyxA-6fivA:
15.4		 3cyxA-6fivA:
31.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CYX_A_ROCA201_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.50A 3cyxA-6fivA:
15.4		 3cyxA-6fivA:
31.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CYX_A_ROCA201_3
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  59
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 0.32A 3cyxB-6fivA:
15.5		 3cyxB-6fivA:
31.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CYX_A_ROCA201_3
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
None
 0.32A 3cyxB-6fivA:
15.5		 3cyxB-6fivA:
31.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D1X_A_ROCA201_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.44A 3d1xB-6fivA:
15.6		 3d1xB-6fivA:
30.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D1Y_A_ROCA201_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 9 ARG A  13
LEU A  28
ASP A  30
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
None
 0.47A 3d1yB-6fivA:
15.8		 3d1yB-6fivA:
30.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D1Z_B_017B201_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.19A 3d1zB-6fivA:
15.7		 3d1zB-6fivA:
30.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D20_A_017A201_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.21A 3d20A-6fivA:
15.6		 3d20A-6fivA:
30.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D20_A_017A201_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.42A 3d20B-6fivA:
15.6		 3d20B-6fivA:
30.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EBZ_B_017B201_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 ARG A  13
LEU A  28
ASP A  30
ALA A  33
ILE A  37
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 ( 4.8A)
 0.59A 3ebzA-6fivA:
15.9		 3ebzA-6fivA:
31.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EBZ_B_017B201_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 LEU A  28
ASP A  30
ALA A  33
ILE A  37
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.45A 3ebzA-6fivA:
15.9		 3ebzA-6fivA:
31.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EBZ_B_017B201_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 11 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  37
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.45A 3ebzB-6fivA:
15.8		 3ebzB-6fivA:
31.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.41A 3ekqA-6fivA:
15.2		 3ekqA-6fivA:
29.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 9 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.19A 3ektA-6fivA:
15.8		 3ektA-6fivA:
29.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 11 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.15A 3ektD-6fivA:
15.5		 3ektD-6fivA:
29.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.35A 3ekvA-6fivA:
15.2		 3ekvA-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 ARG A  13
ASP A  30
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.35A 3ekwA-6fivA:
15.3		 3ekwA-6fivA:
29.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.40A 3ekwB-6fivA:
15.2		 3ekwB-6fivA:
29.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.18A 3ekxA-6fivA:
15.3		 3ekxA-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 10 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.65A 3ekyA-6fivA:
15.4		 3ekyA-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		4 / 8 ASP A  30
GLY A  32
ALA A  33
ASP A  34
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
 0.28A 3el0A-6fivA:
14.8		 3el0A-6fivA:
29.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 11 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.29A 3el1A-6fivA:
15.2		 3el1A-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 11 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.46A 3el1A-6fivA:
15.2		 3el1A-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL4_A_ROCA100_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.28A 3el4A-6fivA:
15.3		 3el4A-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.22A 3el5B-6fivA:
15.0		 3el5B-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 8 ARG A  13
ASP A  30
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.43A 3el9A-6fivA:
15.0		 3el9A-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 10 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.34A 3el9B-6fivA:
15.4		 3el9B-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 11 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.57A 3em4A-6fivA:
15.3		 3em4A-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 9 ARG A  13
ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.57A 3em4B-6fivA:
15.5		 3em4B-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 11 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.60A 3em4U-6fivA:
15.5		 3em4U-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.13A 3gguA-6fivA:
15.8		 3gguA-6fivA:
27.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 9 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.14A 3gguB-6fivA:
15.8		 3gguB-6fivA:
27.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_1
(GAG-POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.44A 3jvyA-6fivA:
15.4		 3jvyA-6fivA:
29.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.44A 3jvyB-6fivA:
15.5		 3jvyB-6fivA:
29.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K4V_D_ROCD201_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
LEU A  28
ASP A  30
ALA A  33
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.51A 3k4vC-6fivA:
15.5		 3k4vC-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K4V_D_ROCD201_3
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.50A 3k4vD-6fivA:
15.4		 3k4vD-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.19A 3lzsA-6fivA:
15.5		 3lzsA-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.45A 3lzsA-6fivA:
15.5		 3lzsA-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.20A 3lzsB-6fivA:
15.5		 3lzsB-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.44A 3lzsB-6fivA:
15.5		 3lzsB-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.17A 3lzuA-6fivA:
15.4		 3lzuA-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.45A 3lzuA-6fivA:
15.4		 3lzuA-6fivA:
29.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LZV_A_017A200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.46A 3lzvA-6fivA:
14.9		 3lzvA-6fivA:
30.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.21A 3mwsA-6fivA:
16.1		 3mwsA-6fivA:
27.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.45A 3n3iA-6fivA:
11.0		 3n3iA-6fivA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
VAL A  99
ILE A  37
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
None
3TL  A 201 ( 4.8A)
 1.21A 3n3iA-6fivA:
11.0		 3n3iA-6fivA:
22.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NDT_D_ROCD100_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.45A 3ndtC-6fivA:
15.4		 3ndtC-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NDT_D_ROCD100_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.47A 3ndtD-6fivA:
15.5		 3ndtD-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NDU_A_ROCA101_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.49A 3nduA-6fivA:
15.3		 3nduA-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NDU_A_ROCA101_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.46A 3nduB-6fivA:
15.5		 3nduB-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NDU_D_ROCD100_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
LEU A  28
ASP A  30
GLY A  32
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-3.4A)
None
 0.49A 3nduC-6fivA:
15.4		 3nduC-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NDU_D_ROCD100_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.49A 3nduD-6fivA:
15.1		 3nduD-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NDW_A_RITA100_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.35A 3ndwA-6fivA:
15.2		 3ndwA-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NDW_A_RITA100_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.49A 3ndwA-6fivA:
15.2		 3ndwA-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NDW_A_RITA100_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 9 ARG A  13
ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.63A 3ndwB-6fivA:
15.1		 3ndwB-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NDX_A_RITA100_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.37A 3ndxA-6fivA:
15.2		 3ndxA-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NDX_A_RITA100_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.50A 3ndxA-6fivA:
15.2		 3ndxA-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NU3_B_478B401_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.45A 3nu3A-6fivA:
15.5		 3nu3A-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NU3_B_478B401_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.25A 3nu3B-6fivA:
15.6		 3nu3B-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NU4_B_478B401_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 9 ASP A  30
ALA A  33
ILE A  37
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
None
 0.93A 3nu4A-6fivA:
15.4		 3nu4A-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NU4_B_478B401_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 9 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ILE A  37
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.39A 3nu4B-6fivA:
15.6		 3nu4B-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NU5_B_478B401_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  59
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 1.35A 3nu5B-6fivA:
15.6		 3nu5B-6fivA:
31.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NU5_B_478B401_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  59
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 0.26A 3nu5B-6fivA:
15.6		 3nu5B-6fivA:
31.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NU6_B_478B401_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.43A 3nu6B-6fivA:
15.6		 3nu6B-6fivA:
30.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NU9_A_478A401_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.15A 3nu9B-6fivA:
15.5		 3nu9B-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NU9_A_478A401_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
None
 0.48A 3nu9B-6fivA:
15.5		 3nu9B-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NUJ_B_478B401_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 9 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.20A 3nujB-6fivA:
15.6		 3nujB-6fivA:
30.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NUO_B_478B478_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 9 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.24A 3nuoB-6fivA:
15.5		 3nuoB-6fivA:
31.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OGP_A_017A200_1
(FIV PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		8 / 9 ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  35
MET A  56
GLY A  58
LEU A 101
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.3A)
3TL  A 201 (-4.7A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.8A)
 0.60A 3ogpA-6fivA:
21.8		 3ogpA-6fivA:
95.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OGP_A_017A200_2
(FIV PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		8 / 10 LEU A  28
ASP A  30
ALA A  33
ILE A  35
MET A  56
GLY A  58
VAL A  99
LEU A 101
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 ( 4.3A)
3TL  A 201 (-4.7A)
3TL  A 201 (-3.4A)
None
3TL  A 201 (-4.8A)
 0.54A 3ogpB-6fivA:
22.0		 3ogpB-6fivA:
95.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OGP_B_017B200_1
(FIV PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		8 / 10 LEU A  28
ASP A  30
ALA A  33
ILE A  35
MET A  56
GLY A  58
VAL A  99
LEU A 101
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 ( 4.3A)
3TL  A 201 (-4.7A)
3TL  A 201 (-3.4A)
None
3TL  A 201 (-4.8A)
 0.64A 3ogpA-6fivA:
21.7		 3ogpA-6fivA:
95.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OGP_B_017B200_2
(FIV PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		8 / 9 ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  35
MET A  56
GLY A  58
LEU A 101
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.3A)
3TL  A 201 (-4.7A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.8A)
 0.46A 3ogpB-6fivA:
22.0		 3ogpB-6fivA:
95.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OGQ_A_AB1A200_1
(FIV PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		8 / 10 LEU A  28
ASP A  30
ALA A  33
ASP A  34
ILE A  35
MET A  56
GLY A  58
LEU A 101
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.3A)
3TL  A 201 (-4.7A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.8A)
 0.52A 3ogqA-6fivA:
21.4		 3ogqA-6fivA:
95.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OGQ_A_AB1A200_2
(FIV PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		8 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  35
MET A  56
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.3A)
3TL  A 201 (-4.7A)
3TL  A 201 (-3.4A)
 0.65A 3ogqB-6fivA:
21.5		 3ogqB-6fivA:
95.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OGQ_A_AB1A200_2
(FIV PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		8 / 12 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  35
GLY A  58
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.3A)
3TL  A 201 (-3.4A)
 0.48A 3ogqB-6fivA:
21.5		 3ogqB-6fivA:
95.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OGQ_A_AB1A200_2
(FIV PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		8 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  35
GLY A  58
LEU A 101
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.3A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.8A)
 0.36A 3ogqB-6fivA:
21.5		 3ogqB-6fivA:
95.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXC_A_ROCA401_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.39A 3oxcA-6fivA:
14.9		 3oxcA-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXC_A_ROCA401_3
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.47A 3oxcB-6fivA:
15.2		 3oxcB-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXV_B_478B200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 9 LEU A  28
ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  59
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 1.33A 3oxvA-6fivA:
15.6		 3oxvA-6fivA:
30.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXV_B_478B200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 9 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  59
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
None
 0.48A 3oxvA-6fivA:
15.6		 3oxvA-6fivA:
30.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXV_C_478C200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 9 LEU A  28
ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  59
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 1.34A 3oxvC-6fivA:
15.7		 3oxvC-6fivA:
30.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXV_C_478C200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 9 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  59
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 0.29A 3oxvC-6fivA:
15.7		 3oxvC-6fivA:
30.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXW_B_017B200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 10 LEU A  28
ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  59
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 1.31A 3oxwA-6fivA:
15.7		 3oxwA-6fivA:
30.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXW_B_017B200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  59
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 0.21A 3oxwA-6fivA:
15.7		 3oxwA-6fivA:
30.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXW_B_017B200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.55A 3oxwA-6fivA:
15.7		 3oxwA-6fivA:
30.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXW_B_017B200_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 LEU A  28
ASP A  30
ALA A  33
GLY A  58
VAL A  59
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 0.22A 3oxwB-6fivA:
15.9		 3oxwB-6fivA:
30.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXW_D_017D200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 10 LEU A  28
ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  59
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 1.30A 3oxwC-6fivA:
15.7		 3oxwC-6fivA:
30.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXW_D_017D200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		8 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  59
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
None
 0.55A 3oxwC-6fivA:
15.7		 3oxwC-6fivA:
30.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXW_D_017D200_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 10 LEU A  28
ASP A  30
ALA A  33
GLY A  58
VAL A  59
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
None
 0.65A 3oxwD-6fivA:
15.8		 3oxwD-6fivA:
30.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXX_A_DR7A100_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		8 / 12 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  59
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 0.30A 3oxxA-6fivA:
15.4		 3oxxA-6fivA:
30.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXX_A_DR7A100_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 11 ARG A  13
LEU A  28
ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  59
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 0.38A 3oxxB-6fivA:
15.4		 3oxxB-6fivA:
30.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXX_A_DR7A100_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 11 ARG A  13
LEU A  28
ASP A  30
ALA A  33
ASP A  34
VAL A  59
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-4.3A)
None
 0.56A 3oxxB-6fivA:
15.4		 3oxxB-6fivA:
30.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXX_C_DR7C100_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		8 / 12 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  59
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 0.30A 3oxxC-6fivA:
15.2		 3oxxC-6fivA:
30.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXX_C_DR7C100_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		8 / 12 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  59
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-4.3A)
None
 0.53A 3oxxC-6fivA:
15.2		 3oxxC-6fivA:
30.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 ARG A  13
LEU A  28
ASP A  30
ALA A  33
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
None
 0.76A 3oy4A-6fivA:
15.0		 3oy4A-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 LEU A  28
ASP A  30
ALA A  33
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.72A 3oy4A-6fivA:
15.0		 3oy4A-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.47A 3oy4B-6fivA:
15.1		 3oy4B-6fivA:
29.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PWM_B_017B402_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.47A 3pwmA-6fivA:
15.4		 3pwmA-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PWM_B_017B402_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.48A 3pwmB-6fivA:
15.7		 3pwmB-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PWR_A_ROCA401_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.49A 3pwrA-6fivA:
15.3		 3pwrA-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PWR_A_ROCA401_3
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.40A 3pwrB-6fivA:
15.6		 3pwrB-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ILE A  37
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.36A 3s43B-6fivA:
15.4		 3s43B-6fivA:
29.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3S45_B_478B201_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 11 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.31A 3s45B-6fivA:
15.8		 3s45B-6fivA:
31.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3S45_B_478B201_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 11 LEU A  28
GLY A  32
ALA A  33
ASP A  34
ILE A  37
GLY A  58
 None
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.55A 3s45B-6fivA:
15.8		 3s45B-6fivA:
31.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 9 ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  37
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.38A 3s53A-6fivA:
15.2		 3s53A-6fivA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 LEU A  28
ASP A  30
ALA A  33
ILE A  37
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.39A 3s53B-6fivA:
15.5		 3s53B-6fivA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  37
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.44A 3s56A-6fivA:
14.8		 3s56A-6fivA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_A_TPVA100_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 ARG A  13
LEU A  28
ALA A  33
ASP A  34
GLY A  58
 None
None
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.38A 3spkA-6fivA:
15.8		 3spkA-6fivA:
29.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ARG A  13
LEU A  28
ALA A  33
ASP A  34
GLY A  58
 None
None
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.38A 3spkB-6fivA:
15.8		 3spkB-6fivA:
29.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		4 / 7 ASP A  30
GLY A  32
ALA A  33
ASP A  34
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
 0.14A 3t3cA-6fivA:
15.2		 3t3cA-6fivA:
28.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKG_B_ROCB801_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.49A 3tkgA-6fivA:
13.8		 3tkgA-6fivA:
30.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKG_B_ROCB801_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.40A 3tkgB-6fivA:
15.5		 3tkgB-6fivA:
30.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKG_C_ROCC901_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.52A 3tkgC-6fivA:
15.2		 3tkgC-6fivA:
30.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKG_C_ROCC901_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.43A 3tkgD-6fivA:
15.5		 3tkgD-6fivA:
30.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKW_B_017B401_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.20A 3tkwA-6fivA:
15.6		 3tkwA-6fivA:
30.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKW_B_017B401_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.45A 3tkwA-6fivA:
15.6		 3tkwA-6fivA:
30.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.24A 3ttpA-6fivA:
15.8		 3ttpA-6fivA:
27.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.19A 3ttpB-6fivA:
15.8		 3ttpB-6fivA:
27.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_1
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 9 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.17A 3u7sA-6fivA:
15.8		 3u7sA-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_2
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 9 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.24A 3u7sB-6fivA:
16.1		 3u7sB-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		3 / 3 PHE A  86
CYH A  84
HIS A  72
 None
 1.07A 3u9fF-6fivA:
undetectable		 3u9fF-6fivA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		3 / 3 PHE A  86
CYH A  84
HIS A  72
 None
 1.11A 3u9fG-6fivA:
undetectable		 3u9fG-6fivA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		3 / 3 PHE A  86
CYH A  84
HIS A  72
 None
 1.08A 3u9fL-6fivA:
undetectable		 3u9fL-6fivA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		3 / 3 PHE A  86
CYH A  84
HIS A  72
 None
 1.06A 3u9fS-6fivA:
undetectable		 3u9fS-6fivA:
17.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UCB_A_017A201_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  37
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.31A 3ucbA-6fivA:
16.0		 3ucbA-6fivA:
32.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UCB_A_017A201_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ILE A  37
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 ( 4.8A)
None
 0.64A 3ucbA-6fivA:
16.0		 3ucbA-6fivA:
32.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UCB_A_017A201_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  37
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.36A 3ucbB-6fivA:
15.9		 3ucbB-6fivA:
32.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UCB_A_017A201_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 LEU A  28
ASP A  30
GLY A  32
ILE A  37
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 ( 4.8A)
None
 0.70A 3ucbB-6fivA:
15.9		 3ucbB-6fivA:
32.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UFN_A_ROCA401_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.34A 3ufnA-6fivA:
15.8		 3ufnA-6fivA:
32.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 9 ARG A  13
LEU A  28
ASP A  30
ALA A  33
ASP A  34
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
 0.58A 3wsjA-6fivA:
12.0		 3wsjA-6fivA:
26.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_2
(ASPARTYL PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.67A 4dqbB-6fivA:
15.3		 4dqbB-6fivA:
28.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_2
(ASPARTYL PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 9 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.24A 4dqcB-6fivA:
15.4		 4dqcB-6fivA:
28.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_1
(ASPARTYL PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 ARG A  13
LEU A  28
ASP A  30
ALA A  33
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
None
 0.70A 4dqeA-6fivA:
15.2		 4dqeA-6fivA:
28.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_2
(ASPARTYL PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.67A 4dqeB-6fivA:
15.3		 4dqeB-6fivA:
28.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_1
(WILD-TYPE HIV-1
PROTEASE DIMER)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 ARG A  13
LEU A  28
ASP A  30
ALA A  33
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
None
 0.76A 4dqhA-6fivA:
15.1		 4dqhA-6fivA:
28.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_2
(WILD-TYPE HIV-1
PROTEASE DIMER)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.63A 4dqhB-6fivA:
15.3		 4dqhB-6fivA:
28.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.19A 4hlaA-6fivA:
15.5		 4hlaA-6fivA:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.58A 4hlaA-6fivA:
15.5		 4hlaA-6fivA:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 11 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.17A 4hlaB-6fivA:
15.5		 4hlaB-6fivA:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 LEU A  28
ASP A  30
GLY A  32
ALA A  33
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
None
 0.56A 4hlaB-6fivA:
15.5		 4hlaB-6fivA:
29.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J5J_B_478B401_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 ASP A  30
ALA A  33
ILE A  37
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
None
 0.76A 4j5jB-6fivA:
16.0		 4j5jB-6fivA:
32.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JEC_B_478B401_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.29A 4jecB-6fivA:
15.4		 4jecB-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.16A 4ll3B-6fivA:
15.5		 4ll3B-6fivA:
28.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A202_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.16A 4ll3A-6fivA:
15.5		 4ll3A-6fivA:
28.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A202_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 9 ARG A  13
ASP A  30
ALA A  33
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.61A 4ll3B-6fivA:
15.5		 4ll3B-6fivA:
28.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NJT_B_017B101_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.17A 4njtB-6fivA:
15.9		 4njtB-6fivA:
31.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NJU_A_TPVA500_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
LEU A  28
ASP A  30
ALA A  33
ASP A  34
GLY A  58
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.42A 4njuA-6fivA:
15.4		 4njuA-6fivA:
31.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NJU_A_TPVA500_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 ARG A  13
LEU A  28
ASP A  30
ALA A  33
GLY A  58
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.42A 4njuB-6fivA:
15.9		 4njuB-6fivA:
31.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NJU_C_TPVC500_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
LEU A  28
ASP A  30
ALA A  33
ASP A  34
GLY A  58
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.44A 4njuC-6fivA:
15.4		 4njuC-6fivA:
31.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NJU_C_TPVC500_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 ARG A  13
LEU A  28
ASP A  30
ALA A  33
GLY A  58
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.42A 4njuD-6fivA:
15.9		 4njuD-6fivA:
31.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NJV_A_RITA500_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.27A 4njvA-6fivA:
15.5		 4njvA-6fivA:
31.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NJV_A_RITA500_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 ARG A  13
ASP A  30
GLY A  32
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.22A 4njvB-6fivA:
15.9		 4njvB-6fivA:
31.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NJV_D_RITD500_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 ARG A  13
ASP A  30
GLY A  32
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.27A 4njvC-6fivA:
15.5		 4njvC-6fivA:
31.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NJV_D_RITD500_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.16A 4njvD-6fivA:
15.9		 4njvD-6fivA:
31.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_2
(ANDROGEN RECEPTOR)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		4 / 6 MET A  56
ILE A  18
ILE A  25
VAL A  20
 3TL  A 201 (-4.7A)
None
None
None
 1.02A 4olmA-6fivA:
undetectable		 4olmA-6fivA:
17.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Q1W_A_017A104_1
(ASPARTYL PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 9 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.45A 4q1wA-6fivA:
15.2		 4q1wA-6fivA:
30.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Q1Y_A_017A106_1
(ASPARTYL PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		8 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  37
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
None
 0.53A 4q1yA-6fivA:
15.3		 4q1yA-6fivA:
30.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Q1Y_A_017A106_2
(ASPARTYL PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
ALA A  33
ILE A  37
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
None
 0.60A 4q1yB-6fivA:
15.3		 4q1yB-6fivA:
30.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QGI_A_ROCA101_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 11 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.52A 4qgiA-6fivA:
15.2		 4qgiA-6fivA:
30.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RVJ_B_478B101_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 9 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.27A 4rvjB-6fivA:
15.8		 4rvjB-6fivA:
31.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RVJ_D_478D101_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 9 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.28A 4rvjD-6fivA:
15.8		 4rvjD-6fivA:
31.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  37
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.33A 5e5jA-6fivA:
15.7		 5e5jA-6fivA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  37
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.32A 5e5kB-6fivA:
15.4		 5e5kB-6fivA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		3 / 3 MET A  56
GLN A  54
ARG A  64
 3TL  A 201 (-4.7A)
3TL  A 201 ( 4.1A)
None
 1.11A 5ewzB-6fivA:
undetectable		 5ewzB-6fivA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQY_B_017B101_2
(PROTEASE E35D-DRV)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		4 / 7 GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.24A 5kqyB-6fivA:
15.7		 5kqyB-6fivA:
29.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_2
(PROTEASE E35D-APV)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 9 LEU A  28
GLY A  32
ALA A  33
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.49A 5kr0B-6fivA:
15.7		 5kr0B-6fivA:
29.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		3 / 3 MET A  56
GLN A  54
ARG A  64
 3TL  A 201 (-4.7A)
3TL  A 201 ( 4.1A)
None
 1.01A 5m35B-6fivA:
undetectable		 5m35B-6fivA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		3 / 3 MET A  56
GLN A  54
ARG A  64
 3TL  A 201 (-4.7A)
3TL  A 201 ( 4.1A)
None
 0.97A 5m36A-6fivA:
undetectable		 5m36A-6fivA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH8_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		3 / 3 CYH A  90
MET A  56
ASN A  55
 None
3TL  A 201 (-4.7A)
None
 1.29A 5qh8A-6fivA:
undetectable		 5qh8A-6fivA:
21.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5T2Z_B_017B201_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.19A 5t2zA-6fivA:
15.7		 5t2zA-6fivA:
30.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  37
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.38A 5t8hA-6fivA:
15.7		 5t8hA-6fivA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_A_HISA402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 GLY A 103
LEU A 102
VAL A  89
VAL A  20
LEU A  73
 None
 1.11A 6czmA-6fivA:
undetectable
6czmC-6fivA:
undetectable		 6czmA-6fivA:
14.49
6czmC-6fivA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_B_HISB402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 9 VAL A  20
LEU A  73
GLY A 103
LEU A 102
VAL A  89
 None
 1.07A 6czmA-6fivA:
undetectable
6czmB-6fivA:
undetectable		 6czmA-6fivA:
14.49
6czmB-6fivA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_C_HISC402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 9 VAL A  20
LEU A  73
GLY A 103
LEU A 102
VAL A  89
 None
 1.12A 6czmB-6fivA:
undetectable
6czmC-6fivA:
undetectable		 6czmB-6fivA:
14.49
6czmC-6fivA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_E_HISE402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 9 VAL A  20
LEU A  73
GLY A 103
LEU A 102
VAL A  89
 None
 1.10A 6czmD-6fivA:
undetectable
6czmE-6fivA:
undetectable		 6czmD-6fivA:
14.49
6czmE-6fivA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_F_HISF402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 VAL A  20
LEU A  73
GLY A 103
LEU A 102
VAL A  89
 None
 1.08A 6czmE-6fivA:
undetectable
6czmF-6fivA:
undetectable		 6czmE-6fivA:
14.49
6czmF-6fivA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_0
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.21A 6dgxA-6fivA:
15.4		 6dgxA-6fivA:
29.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_0
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.50A 6dgxA-6fivA:
15.4		 6dgxA-6fivA:
29.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 LEU A  28
ASP A  30
ALA A  33
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.43A 6dgxB-6fivA:
15.2		 6dgxB-6fivA:
29.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_0
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.26A 6dh0A-6fivA:
15.4		 6dh0A-6fivA:
29.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_0
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.49A 6dh0A-6fivA:
15.4		 6dh0A-6fivA:
29.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH3_A_017A101_0
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.25A 6dh3A-6fivA:
15.4		 6dh3A-6fivA:
29.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH3_A_017A101_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.25A 6dh3B-6fivA:
15.3		 6dh3B-6fivA:
29.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DH6_A_017A104_0
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  59
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 0.34A 6dh6A-6fivA:
15.4		 6dh6A-6fivA:
31.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DH6_A_017A104_0
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  59
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-4.3A)
None
 0.56A 6dh6A-6fivA:
15.4		 6dh6A-6fivA:
31.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DH6_A_017A104_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.27A 6dh6B-6fivA:
15.2		 6dh6B-6fivA:
31.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DIF_B_TPVB201_0
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 ARG A  13
LEU A  28
ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.49A 6difA-6fivA:
15.3		 6difA-6fivA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DIF_B_TPVB201_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.45A 6difB-6fivA:
15.5		 6difB-6fivA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DIL_B_TPVB201_0
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 ARG A  13
LEU A  28
ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.59A 6dilA-6fivA:
15.3		 6dilA-6fivA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DJ1_B_AB1B201_0
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.53A 6dj1A-6fivA:
15.4		 6dj1A-6fivA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DJ1_B_AB1B201_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.75A 6dj1B-6fivA:
15.6		 6dj1B-6fivA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DJ1_B_AB1B201_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.24A 6dj1B-6fivA:
15.6		 6dj1B-6fivA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DJ2_B_AB1B201_0
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.66A 6dj2A-6fivA:
15.4		 6dj2A-6fivA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DJ2_B_AB1B201_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.56A 6dj2B-6fivA:
15.6		 6dj2B-6fivA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DJ2_B_AB1B201_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.68A 6dj2B-6fivA:
15.6		 6dj2B-6fivA:
30.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		3 / 3 MET A  56
GLN A  54
ARG A  64
 3TL  A 201 (-4.7A)
3TL  A 201 ( 4.1A)
None
 0.99A 6fn9A-6fivA:
undetectable		 6fn9A-6fivA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		3 / 3 MET A  56
GLN A  54
ARG A  64
 3TL  A 201 (-4.7A)
3TL  A 201 ( 4.1A)
None
 1.03A 6fnaB-6fivA:
undetectable		 6fnaB-6fivA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNB_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		3 / 3 MET A  56
GLN A  54
ARG A  64
 3TL  A 201 (-4.7A)
3TL  A 201 ( 4.1A)
None
 0.98A 6fnbA-6fivA:
undetectable		 6fnbA-6fivA:
18.26