SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fju'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 6fju -
(-) 		4 / 7 HIS A  85
ASP A  96
ILE A  97
VAL A 142
 ZN  A 301 (-3.2A)
ZN  A 301 (-2.5A)
None
None
 0.87A 3fi0E-6fjuA:
undetectable		 3fi0E-6fjuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_M_TRPM1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 6fju -
(-) 		5 / 9 VAL A 114
HIS A  85
ASP A  96
ILE A  97
VAL A 142
 None
ZN  A 301 (-3.2A)
ZN  A 301 (-2.5A)
None
None
 1.11A 3fi0M-6fjuA:
undetectable		 3fi0M-6fjuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_P_TRPP1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 6fju -
(-) 		4 / 7 VAL A 114
HIS A  85
ASP A  96
ILE A  97
 None
ZN  A 301 (-3.2A)
ZN  A 301 (-2.5A)
None
 0.94A 3fi0P-6fjuA:
undetectable		 3fi0P-6fjuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 6fju -
(-) 		5 / 12 GLY A  50
TYR A  82
LEU A  28
VAL A  65
HIS A  16
 None
 1.25A 3g9eA-6fjuA:
undetectable		 3g9eA-6fjuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_1
(O-METHYLTRANSFERASE)		 6fju -
(-) 		3 / 3 ASP A  96
PHE A  91
SER A  84
 ZN  A 301 (-2.5A)
None
None
 0.75A 3i5uB-6fjuA:
undetectable		 3i5uB-6fjuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)		 6fju -
(-) 		5 / 12 VAL A  13
LEU A  38
ILE A  40
ILE A   5
VAL A 133
 None
 0.82A 4y0pA-6fjuA:
undetectable		 4y0pA-6fjuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_1
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 6fju -
(-) 		3 / 3 ASP A 168
GLU A  68
SER A  19
 None
 0.80A 5bw4B-6fjuA:
undetectable		 5bw4B-6fjuA:
undetectable