SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fjy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QK8_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 6fjy PROTEIN CSUE
(Acinetobacter
baumannii) 		5 / 12 GLU D  66
VAL D 116
ILE D 175
LEU D 110
PRO D 111
 None
 1.20A 2qk8A-6fjyD:
undetectable		 2qk8A-6fjyD:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_GLYA333_0
(CHOLOYLGLYCINE
HYDROLASE)		 6fjy PROTEIN CSUE
(Acinetobacter
baumannii) 		3 / 3 ASN D 221
ASN D 222
ARG D 255
 None
 0.61A 2rlcA-6fjyD:
undetectable		 2rlcA-6fjyD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6fjy PROTEIN CSUE
(Acinetobacter
baumannii) 		4 / 5 GLN D  28
PHE D 106
LEU D 173
PHE D  59
 None
 1.40A 3ablC-6fjyD:
undetectable
3ablJ-6fjyD:
undetectable		 3ablC-6fjyD:
undetectable
3ablJ-6fjyD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BC9_A_ACRA901_1
(ALPHA AMYLASE,
CATALYTIC REGION)		 6fjy PROTEIN CSUE
(Acinetobacter
baumannii) 		4 / 7 ASP D  87
SER D  89
SER D 134
GLU D 148
 None
 0.99A 3bc9A-6fjyD:
2.7		 3bc9A-6fjyD:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YOA_A_017A100_1
(HIV-1 PROTEASE)		 6fjy PROTEIN CSUE
(Acinetobacter
baumannii) 		4 / 6 ASN D 213
PRO D 272
THR D 279
VAL D 212
 None
 1.08A 4yoaA-6fjyD:
undetectable		 4yoaA-6fjyD:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 6fjy PROTEIN CSUE
(Acinetobacter
baumannii) 		4 / 7 SER D 204
ASP D 246
ARG D 255
GLU D 261
 None
 0.85A 5btfA-6fjyD:
undetectable
5btfC-6fjyD:
undetectable
5btfD-6fjyD:
undetectable		 5btfA-6fjyD:
11.11
5btfC-6fjyD:
11.11
5btfD-6fjyD:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 6fjy PROTEIN CSUE
(Acinetobacter
baumannii) 		3 / 3 ASP D 168
PHE D 132
ARG D  51
 None
 1.12A 5yw0A-6fjyD:
undetectable		 5yw0A-6fjyD:
undetectable