SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fks'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 6fks -
(-) 		3 / 3 LYS A  77
ASP A 268
ASP A 270
 None
 1.11A 2br4A-6fksA:
undetectable		 2br4A-6fksA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_1
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT)		 6fks -
(-) 		5 / 10 LEU A  95
TRP A  18
TYR A 237
GLY A 285
GLY A 286
 None
 1.14A 3ls4H-6fksA:
undetectable		 3ls4H-6fksA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_1
(ADENOSYLHOMOCYSTEINA
SE)		 6fks -
(-) 		5 / 12 THR A 280
ASP A 274
HIS A 215
MET A 265
PHE A 266
 HEM  A 301 (-3.0A)
None
HEM  A 301 (-3.3A)
HEM  A 301 (-3.1A)
None
 1.33A 3ondA-6fksA:
undetectable		 3ondA-6fksA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_D_SALD404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 6fks -
(-) 		4 / 5 ALA A 290
PRO A 291
TYR A 170
ALA A  73
 None
 1.41A 3twpD-6fksA:
undetectable		 3twpD-6fksA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_1
(ADENOSINE KINASE,
PUTATIVE)		 6fks -
(-) 		5 / 12 ILE A 230
VAL A 219
LEU A 262
GLY A 144
ASP A 143
 HEM  A 301 ( 4.2A)
HEM  A 301 (-3.7A)
HEM  A 301 ( 4.2A)
GOL  A 303 (-2.9A)
GOL  A 303 ( 2.3A)
 1.07A 3uq6A-6fksA:
undetectable		 3uq6A-6fksA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_1
(ADENOSINE KINASE,
PUTATIVE)		 6fks -
(-) 		5 / 12 ILE A 230
VAL A 219
LEU A 262
GLY A 144
ASP A 143
 HEM  A 301 ( 4.2A)
HEM  A 301 (-3.7A)
HEM  A 301 ( 4.2A)
GOL  A 303 (-2.9A)
GOL  A 303 ( 2.3A)
 1.08A 3uq6B-6fksA:
undetectable		 3uq6B-6fksA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 6fks -
(-) 		5 / 12 ILE A 230
VAL A 219
LEU A 262
GLY A 144
ASP A 143
 HEM  A 301 ( 4.2A)
HEM  A 301 (-3.7A)
HEM  A 301 ( 4.2A)
GOL  A 303 (-2.9A)
GOL  A 303 ( 2.3A)
 1.06A 3vasA-6fksA:
undetectable		 3vasA-6fksA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6fks -
(-) 		5 / 12 PHE A 130
ILE A 127
GLY A 242
GLY A 245
LEU A 138
 None
 1.07A 4e1gB-6fksA:
undetectable		 4e1gB-6fksA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 6fks -
(-) 		4 / 7 GLU A 134
GLU A 135
GLY A 140
ARG A 136
 None
GOL  A 303 ( 4.6A)
GOL  A 302 ( 3.1A)
None
 0.96A 4fgzA-6fksA:
undetectable		 4fgzA-6fksA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 6fks -
(-) 		5 / 12 ALA A  73
GLY A  60
PHE A 289
LEU A  23
ASN A  62
 None
 0.89A 4n49A-6fksA:
undetectable		 4n49A-6fksA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_B_C2FB4000_1
(DIHYDROPTEROATE
SYNTHASE DHPS)		 6fks -
(-) 		4 / 4 LYS A  24
ASN A  62
ASP A  78
ASP A 122
 None
 1.48A 4o1eB-6fksA:
undetectable		 4o1eB-6fksA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 6fks -
(-) 		4 / 8 SER A  34
ALA A  33
LEU A  94
LEU A  23
 None
 0.93A 5dzkF-6fksA:
undetectable
5dzkT-6fksA:
undetectable		 5dzkF-6fksA:
undetectable
5dzkT-6fksA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_B_BEZB306_0
(BETA-LACTAMASE VIM-2)		 6fks -
(-) 		3 / 3 HIS A 103
ASN A 106
ALA A 110
 None
 0.52A 5n4tB-6fksA:
undetectable		 5n4tB-6fksA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_B_ADNB502_1
(-)		 6fks -
(-) 		5 / 12 ASP A 274
HIS A 178
HIS A 215
MET A 265
PHE A 266
 None
HEM  A 301 (-4.2A)
HEM  A 301 (-3.3A)
HEM  A 301 (-3.1A)
None
 1.47A 6f3mB-6fksA:
undetectable		 6f3mB-6fksA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_D_ADND502_1
(-)		 6fks -
(-) 		5 / 12 ASP A 274
HIS A 178
HIS A 215
MET A 265
PHE A 266
 None
HEM  A 301 (-4.2A)
HEM  A 301 (-3.3A)
HEM  A 301 (-3.1A)
None
 1.47A 6f3mD-6fksA:
undetectable		 6f3mD-6fksA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_B_ADNB505_1
(-)		 6fks -
(-) 		5 / 12 THR A 280
ASP A 274
HIS A 215
MET A 265
PHE A 266
 HEM  A 301 (-3.0A)
None
HEM  A 301 (-3.3A)
HEM  A 301 (-3.1A)
None
 1.33A 6f3nB-6fksA:
undetectable		 6f3nB-6fksA:
undetectable