SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6flk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_E_NCAE507_0
(NAD-DEPENDENT
DEACETYLASE 2)		 6flk CEP120
(Homo
sapiens) 		4 / 7 ILE A 475
LEU A 505
ASN A 473
ILE A 472
 None
 0.92A 1yc2E-6flkA:
undetectable		 1yc2E-6flkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)		 6flk CEP120
(Homo
sapiens) 		3 / 3 TYR A 509
TYR A 478
ILE A 489
 None
 0.78A 3eteA-6flkA:
undetectable
3eteB-6flkA:
undetectable		 3eteA-6flkA:
9.21
3eteB-6flkA:
9.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_2
(GLUCOCORTICOID
RECEPTOR)		 6flk CEP120
(Homo
sapiens) 		3 / 3 MET A 501
CYH A 474
PRO A 471
 None
 1.15A 3h52C-6flkA:
undetectable		 3h52C-6flkA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RMJ_A_NCAA402_0
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-2)		 6flk CEP120
(Homo
sapiens) 		5 / 7 ILE A 475
LEU A 505
LEU A 534
ASN A 473
ILE A 472
 None
 0.99A 4rmjA-6flkA:
undetectable		 4rmjA-6flkA:
undetectable