SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6flm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K5Q_B_PACB559_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 6flm E3 UBIQUITIN/ISG15
LIGASE TRIM25
(Homo
sapiens) 		4 / 7 ALA A 466
TYR A 488
SER A 473
ALA A 479
 None
 0.99A 1k5qA-6flmA:
undetectable
1k5qB-6flmA:
undetectable		 1k5qA-6flmA:
undetectable
1k5qB-6flmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_A_ACTA601_0
(CHOLINE OXIDASE)		 6flm E3 UBIQUITIN/ISG15
LIGASE TRIM25
(Homo
sapiens) 		4 / 5 ILE A 511
HIS A 585
VAL A 440
ASN A 582
 None
 1.39A 3nneA-6flmA:
undetectable		 3nneA-6flmA:
undetectable