SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fls'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CR5_X_PNTX95_0 (PROTEIN S100-B)	6fls	- (-)	3 / 3	CYH A 65 PHE A 45 PHE A 47	None	1.03A	3cr5X-6flsA: undetectable	3cr5X-6flsA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EM0_B_CHDB153_0 (ILEAL BILE ACID-BINDING PROTEIN)	6fls	- (-)	4 / 7	ILE A 42 PHE A 72 PHE A 77 GLY A 39	None	1.08A	3em0B-6flsA: undetectable	3em0B-6flsA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C9W_A_VGHA1158_1 (7,8-DIHYDRO-8-OXOGUA NINE TRIPHOSPHATASE)	6fls	- (-)	5 / 12	PHE A 87 PHE A 92 MET A 107 VAL A 105 PHE A 72	None	1.13A	4c9wA-6flsA: undetectable	4c9wA-6flsA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UDC_A_DEXA1778_2 (GLUCOCORTICOID RECEPTOR)	6fls	- (-)	3 / 3	MET A 107 GLN A 123 TYR A 124	None	1.14A	4udcA-6flsA: undetectable	4udcA-6flsA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IGV_A_ZITA404_2 (MACROLIDE 2'-PHOSPHOTRANSFERAS E II)	6fls	- (-)	4 / 4	ASN A 121 ILE A 108 TYR A 126 PHE A 167	None None GOL A 304 (-3.7A) None	1.43A	5igvA-6flsA: undetectable	5igvA-6flsA: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3CR5_X_PNTX95_0","PROTEIN S100-B","6fls","-","-",3,"CYH A  65;PHE A  45;PHE A  47","None","1.03A","3cr5X-6flsA:undetectable","3cr5X-6flsA:undetectable"],["3EM0_B_CHDB153_0","ILEAL BILE ACID-BINDING PROTEIN","6fls","-","-",4,"ILE A  42;PHE A  72;PHE A  77;GLY A  39","None","1.08A","3em0B-6flsA:undetectable","3em0B-6flsA:undetectable"],["4C9W_A_VGHA1158_1","7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE","6fls","-","-",5,"PHE A  87;PHE A  92;MET A 107;VAL A 105;PHE A  72","None","1.13A","4c9wA-6flsA:undetectable","4c9wA-6flsA:undetectable"],["4UDC_A_DEXA1778_2","GLUCOCORTICOID RECEPTOR","6fls","-","-",3,"MET A 107;GLN A 123;TYR A 124","None","1.14A","4udcA-6flsA:undetectable","4udcA-6flsA:undetectable"],["5IGV_A_ZITA404_2","MACROLIDE 2'-PHOSPHOTRANSFERASE II","6fls","-","-",4,"ASN A 121;ILE A 108;TYR A 126;PHE A 167","None;None;GOL A 304 (-3.7A);None","1.43A","5igvA-6flsA:undetectable","5igvA-6flsA:undetectable"]]