SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6flx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 6flx ABC TRANSPORTER
SYSTEM, ATP-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		4 / 7 LEU A 224
VAL A  60
GLY A  61
VAL A 248
 None
 0.94A 1t88A-6flxA:
undetectable		 1t88A-6flxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PMZ_E_TUBE220_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 6flx ABC TRANSPORTER
SYSTEM, ATP-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		4 / 6 MET A  98
ILE A  95
SER A  30
SER A  31
 None
 1.36A 3pmzD-6flxA:
undetectable		 3pmzD-6flxA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1F_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 6flx ABC TRANSPORTER
SYSTEM, ATP-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		5 / 12 LEU A 185
SER A 187
LEU A 216
PHE A  74
ILE A 181
 None
 0.99A 4x1fA-6flxA:
undetectable		 4x1fA-6flxA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1G_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 6flx ABC TRANSPORTER
SYSTEM, ATP-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		5 / 12 LEU A 185
SER A 187
LEU A 216
PHE A  74
ILE A 181
 None
 1.00A 4x1gA-6flxA:
undetectable		 4x1gA-6flxA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		 6flx ABC TRANSPORTER
SYSTEM, ATP-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		5 / 11 VAL A 230
ASP A 227
THR A 226
TYR A 267
LEU A 268
 None
 1.14A 5jh7B-6flxA:
undetectable		 5jh7B-6flxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)		 6flx ABC TRANSPORTER
SYSTEM, ATP-BINDING
PROTEIN
(Burkholderia
pseudomallei) 		5 / 11 VAL A 230
ASP A 227
THR A 226
TYR A 267
LEU A 268
 None
 1.15A 5jh7D-6flxA:
undetectable		 5jh7D-6flxA:
undetectable