SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6flz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 6flz -
(-) 		5 / 10 LEU A  95
GLY A  59
GLY A  58
VAL A  92
ILE A  38
 None
 0.90A 1sdtA-6flzA:
undetectable		 1sdtA-6flzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW4_A_TICA600_1
(CYTOCHROME P450 2B4)		 6flz -
(-) 		5 / 11 ILE A  78
ILE A  32
SER A  34
PHE A  97
GLY A 108
 None
 0.95A 3kw4A-6flzA:
undetectable		 3kw4A-6flzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_D_ACTD605_0
(GBAA_1210 PROTEIN)		 6flz -
(-) 		4 / 6 VAL A  92
SER A  94
THR A  82
GLY A  80
 None
 1.15A 3tj7C-6flzA:
undetectable
3tj7D-6flzA:
undetectable		 3tj7C-6flzA:
undetectable
3tj7D-6flzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 6flz -
(-) 		5 / 12 ASP A  39
ILE A  38
LEU A  91
GLU A 110
GLY A 108
 MMA  A 201 (-2.7A)
None
None
None
None
 1.31A 5k7uA-6flzA:
undetectable		 5k7uA-6flzA:
undetectable