SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fn4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQY_A_ADNA400_1
(MEMBRANE LIPOPROTEIN
TMPC)		 6fn4 UIC2 ANTIGEN BINDING
FRAGMENT HEAVY CHAIN
(Mus
musculus) 		5 / 12 ASP C  90
PHE C  64
MET C  81
PHE C  70
GLY C  66
 None
 1.23A 2fqyA-6fn4C:
undetectable		 2fqyA-6fn4C:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 6fn4 UIC2 ANTIGEN BINDING
FRAGMENT HEAVY CHAIN
(Mus
musculus) 		3 / 3 SER C 212
ALA C 207
VAL C 206
 None
 0.60A 4o2bA-6fn4C:
undetectable		 4o2bA-6fn4C:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 6fn4 UIC2 ANTIGEN BINDING
FRAGMENT HEAVY CHAIN
(Mus
musculus) 		5 / 12 ILE C 101
SER C  52
PHE C  50
ARG C  98
PRO C 108
 None
 1.15A 5ergB-6fn4C:
undetectable		 5ergB-6fn4C:
undetectable