SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fno'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 6fno -
(-) 		5 / 9 VAL A 114
HIS A  85
ASP A  96
ILE A  97
VAL A 142
 None
ZN  A 201 (-3.2A)
ZN  A 201 (-2.1A)
None
None
 1.09A 3fi0C-6fnoA:
undetectable		 3fi0C-6fnoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 6fno -
(-) 		4 / 7 VAL A 114
HIS A  85
ASP A  96
ILE A  97
 None
ZN  A 201 (-3.2A)
ZN  A 201 (-2.1A)
None
 0.82A 3fi0E-6fnoA:
undetectable		 3fi0E-6fnoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 6fno -
(-) 		5 / 9 VAL A 114
HIS A  85
ASP A  96
ILE A  97
VAL A 142
 None
ZN  A 201 (-3.2A)
ZN  A 201 (-2.1A)
None
None
 1.10A 3fi0H-6fnoA:
undetectable		 3fi0H-6fnoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 6fno -
(-) 		5 / 9 VAL A 114
HIS A  85
ASP A  96
ILE A  97
VAL A 142
 None
ZN  A 201 (-3.2A)
ZN  A 201 (-2.1A)
None
None
 1.11A 3fi0K-6fnoA:
undetectable		 3fi0K-6fnoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_M_TRPM1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 6fno -
(-) 		5 / 9 VAL A 114
HIS A  85
ASP A  96
ILE A  97
VAL A 142
 None
ZN  A 201 (-3.2A)
ZN  A 201 (-2.1A)
None
None
 1.06A 3fi0M-6fnoA:
undetectable		 3fi0M-6fnoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_O_TRPO1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 6fno -
(-) 		5 / 9 VAL A 114
HIS A  85
ASP A  96
ILE A  97
VAL A 142
 None
ZN  A 201 (-3.2A)
ZN  A 201 (-2.1A)
None
None
 1.07A 3fi0O-6fnoA:
undetectable		 3fi0O-6fnoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_P_TRPP1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 6fno -
(-) 		4 / 7 VAL A 114
HIS A  85
ASP A  96
ILE A  97
 None
ZN  A 201 (-3.2A)
ZN  A 201 (-2.1A)
None
 0.85A 3fi0P-6fnoA:
undetectable		 3fi0P-6fnoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_1
(O-METHYLTRANSFERASE)		 6fno -
(-) 		3 / 3 ASP A  96
PHE A  91
SER A  84
 ZN  A 201 (-2.1A)
None
None
 0.82A 3i5uB-6fnoA:
undetectable		 3i5uB-6fnoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 6fno -
(-) 		4 / 5 HIS A  83
HIS A  85
VAL A 114
ALA A 112
 ZN  A 201 (-3.2A)
ZN  A 201 (-3.2A)
None
None
 1.21A 5i3bB-6fnoA:
undetectable		 5i3bB-6fnoA:
undetectable