SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fnz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
6fnz NEURONAL MIGRATION
PROTEIN DOUBLECORTIN

(Homo
sapiens)
4 / 6 ASP A 313
THR A 311
TYR A 310
HIS A 321
None
1.27A 2eimN-6fnzA:
undetectable
2eimP-6fnzA:
undetectable
2eimN-6fnzA:
undetectable
2eimP-6fnzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)
6fnz NEURONAL MIGRATION
PROTEIN DOUBLECORTIN

(Homo
sapiens)
3 / 3 ARG A 267
GLU A 302
THR A 303
None
0.85A 3v4tA-6fnzA:
undetectable
3v4tA-6fnzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
6fnz NEURONAL MIGRATION
PROTEIN DOUBLECORTIN

(Homo
sapiens)
4 / 7 ASP A 313
THR A 311
TYR A 310
HIS A 321
None
1.22A 6nmfN-6fnzA:
undetectable
6nmfP-6fnzA:
undetectable
6nmfN-6fnzA:
undetectable
6nmfP-6fnzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
6fnz NEURONAL MIGRATION
PROTEIN DOUBLECORTIN

(Homo
sapiens)
4 / 6 ASP A 313
THR A 311
TYR A 310
HIS A 321
None
1.23A 6nmpA-6fnzA:
undetectable
6nmpC-6fnzA:
undetectable
6nmpA-6fnzA:
undetectable
6nmpC-6fnzA:
undetectable