SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fof'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6fof GALECTIN-3,GALECTIN-
3
(Homo
sapiens) 		3 / 3 VAL C 155
ALA C 156
HIS C 223
 None
 0.68A 1q23J-6fofC:
undetectable		 1q23J-6fofC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_1
(PHOSPHOLIPASE A2)		 6fof GALECTIN-3,GALECTIN-
3
(Homo
sapiens) 		4 / 5 VAL C 172
PHE C 149
ARG C 186
ARG C 169
 None
None
LAT  C 301 (-4.0A)
None
 1.38A 3bjwE-6fofC:
undetectable		 3bjwE-6fofC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_A_1GNA998_1
(GALECTIN-7)		 6fof GALECTIN-3,GALECTIN-
3
(Homo
sapiens) 		6 / 6 HIS C 158
ASN C 160
ARG C 162
ASN C 174
TRP C 181
GLU C 184
 LAT  C 301 (-3.8A)
LAT  C 301 (-4.1A)
LAT  C 301 (-2.7A)
LAT  C 301 (-3.8A)
LAT  C 301 (-3.8A)
LAT  C 301 ( 2.8A)
 0.26A 3galA-6fofC:
22.3		 3galA-6fofC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_B_1GNB999_1
(GALECTIN-7)		 6fof GALECTIN-3,GALECTIN-
3
(Homo
sapiens) 		6 / 6 HIS C 158
ASN C 160
ARG C 162
ASN C 174
TRP C 181
GLU C 184
 LAT  C 301 (-3.8A)
LAT  C 301 (-4.1A)
LAT  C 301 (-2.7A)
LAT  C 301 (-3.8A)
LAT  C 301 (-3.8A)
LAT  C 301 ( 2.8A)
 0.42A 3galB-6fofC:
22.3		 3galB-6fofC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_C_T44C128_1
(5-HYDROXYISOURATE
HYDROLASE)		 6fof GALECTIN-3,GALECTIN-
3
(Homo
sapiens) 		4 / 6 LEU C 147
PRO C 161
LEU C 218
LEU C 219
 None
 1.11A 3q1eA-6fofC:
undetectable
3q1eC-6fofC:
undetectable		 3q1eA-6fofC:
undetectable
3q1eC-6fofC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_C_T44C128_1
(5-HYDROXYISOURATE
HYDROLASE)		 6fof GALECTIN-3,GALECTIN-
3
(Homo
sapiens) 		4 / 6 LEU C 218
LEU C 219
LEU C 147
PRO C 161
 None
 1.07A 3q1eA-6fofC:
undetectable
3q1eC-6fofC:
undetectable		 3q1eA-6fofC:
undetectable
3q1eC-6fofC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		 6fof GALECTIN-3,GALECTIN-
3
(Homo
sapiens) 		4 / 7 ARG C 186
ASN C 166
GLU C 165
ARG C 162
 LAT  C 301 (-4.0A)
None
LAT  C 301 ( 4.7A)
LAT  C 301 (-2.7A)
 1.16A 6b8kA-6fofC:
27.8		 6b8kA-6fofC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		 6fof GALECTIN-3,GALECTIN-
3
(Homo
sapiens) 		7 / 7 HIS C 158
ASN C 160
ARG C 162
ASN C 174
TRP C 181
GLU C 184
ARG C 186
 LAT  C 301 (-3.8A)
LAT  C 301 (-4.1A)
LAT  C 301 (-2.7A)
LAT  C 301 (-3.8A)
LAT  C 301 (-3.8A)
LAT  C 301 ( 2.8A)
LAT  C 301 (-4.0A)
 0.27A 6b8kA-6fofC:
27.8		 6b8kA-6fofC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		 6fof GALECTIN-3,GALECTIN-
3
(Homo
sapiens) 		4 / 8 ARG C 186
ASN C 166
GLU C 165
ARG C 162
 LAT  C 301 (-4.0A)
None
LAT  C 301 ( 4.7A)
LAT  C 301 (-2.7A)
 1.16A 6b94A-6fofC:
19.2		 6b94A-6fofC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		 6fof GALECTIN-3,GALECTIN-
3
(Homo
sapiens) 		7 / 8 HIS C 158
ASN C 160
ARG C 162
ASN C 174
TRP C 181
GLU C 184
ARG C 186
 LAT  C 301 (-3.8A)
LAT  C 301 (-4.1A)
LAT  C 301 (-2.7A)
LAT  C 301 (-3.8A)
LAT  C 301 (-3.8A)
LAT  C 301 ( 2.8A)
LAT  C 301 (-4.0A)
 0.59A 6b94A-6fofC:
19.2		 6b94A-6fofC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_B_W9TB201_0
(GALECTIN-1)		 6fof GALECTIN-3,GALECTIN-
3
(Homo
sapiens) 		7 / 10 HIS C 158
ASN C 160
ARG C 162
ASN C 174
TRP C 181
GLU C 184
ARG C 186
 LAT  C 301 (-3.8A)
LAT  C 301 (-4.1A)
LAT  C 301 (-2.7A)
LAT  C 301 (-3.8A)
LAT  C 301 (-3.8A)
LAT  C 301 ( 2.8A)
LAT  C 301 (-4.0A)
 0.45A 6b94A-6fofC:
19.2
6b94B-6fofC:
18.5		 6b94A-6fofC:
undetectable
6b94B-6fofC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB302_1
(BIFUNCTIONAL PROTEIN
FOLD)		 6fof GALECTIN-3,GALECTIN-
3
(Homo
sapiens) 		5 / 12 LEU C 242
LEU C 120
PRO C 121
ILE C 132
VAL C 202
 None
 1.12A 6debB-6fofC:
undetectable		 6debB-6fofC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FK2_A_SORA302_0
(GALECTIN-3)		 6fof GALECTIN-3,GALECTIN-
3
(Homo
sapiens) 		4 / 4 ARG C 162
GLU C 165
GLU C 184
ARG C 186
 LAT  C 301 (-2.7A)
LAT  C 301 ( 4.7A)
LAT  C 301 ( 2.8A)
LAT  C 301 (-4.0A)
 0.22A 6fk2A-6fofC:
27.9		 6fk2A-6fofC:
undetectable