SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fos'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		4 / 8 GLY B 586
HIS B 593
THR B 589
ILE B 585
 None
 0.81A 1c9sI-6fosB:
undetectable
1c9sJ-6fosB:
undetectable		 1c9sI-6fosB:
undetectable
1c9sJ-6fosB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		4 / 8 GLY B 586
HIS B 593
THR B 589
ILE B 585
 None
 0.81A 1c9sU-6fosB:
undetectable
1c9sV-6fosB:
undetectable		 1c9sU-6fosB:
undetectable
1c9sV-6fosB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_1
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		4 / 7 TYR B 123
THR B 365
SER B 116
TYR B 119
 None
 1.48A 1eiiA-6fosB:
undetectable		 1eiiA-6fosB:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JB0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		8 / 9 MET A 681
PHE A 682
GLY A 686
ARG A 687
TRP A 690
ALA A 714
LEU A 715
GLY A 720
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
PQN  A2001 ( 3.9A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
None
 0.79A 1jb0A-6fosA:
47.2		 1jb0A-6fosA:
81.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JB0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		8 / 9 MET A 681
PHE A 682
SER A 685
GLY A 686
ARG A 687
TRP A 690
ALA A 714
LEU A 715
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
PQN  A2001 (-4.4A)
PQN  A2001 ( 3.9A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.87A 1jb0A-6fosA:
47.2		 1jb0A-6fosA:
81.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		7 / 9 MET B 660
PHE B 661
SER B 664
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.84A 1jb0A-6fosB:
27.3		 1jb0A-6fosB:
6.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		8 / 11 TRP A  46
MET A 681
PHE A 682
ARG A 687
TRP A 690
ILE A 694
ALA A 714
LEU A 715
 None
PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
None
PQN  A2001 ( 3.2A)
None
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.70A 1jb0B-6fosA:
31.4		 1jb0B-6fosA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		8 / 11 TRP A  46
PHE A 682
SER A 685
ARG A 687
TRP A 690
ILE A 694
ALA A 714
LEU A 715
 None
PQN  A2001 (-4.3A)
PQN  A2001 (-4.4A)
None
PQN  A2001 ( 3.2A)
None
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.77A 1jb0B-6fosA:
31.4		 1jb0B-6fosA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		9 / 11 TRP B  22
MET B 660
PHE B 661
SER B 664
ARG B 666
TRP B 669
ILE B 673
ALA B 697
LEU B 698
 None
PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
None
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.76A 1jb0B-6fosB:
32.3		 1jb0B-6fosB:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		9 / 11 TRP B  22
MET B 660
PHE B 661
SER B 664
TRP B 669
ILE B 673
ALA B 697
LEU B 698
ALA B 703
 None
PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
PQN  B2002 (-3.3A)
None
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 0.65A 1jb0B-6fosB:
32.3		 1jb0B-6fosB:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		8 / 11 TRP B  22
PHE B 661
TRP B 665
ARG B 666
TRP B 669
ILE B 673
ALA B 697
LEU B 698
 None
PQN  B2002 ( 4.3A)
None
None
PQN  B2002 (-3.3A)
None
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 1.07A 1jb0B-6fosB:
32.3		 1jb0B-6fosB:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		8 / 11 TRP B  22
PHE B 661
TRP B 665
TRP B 669
ILE B 673
ALA B 697
LEU B 698
ALA B 703
 None
PQN  B2002 ( 4.3A)
None
PQN  B2002 (-3.3A)
None
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 0.96A 1jb0B-6fosB:
32.3		 1jb0B-6fosB:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC1200_1
(PROTEIN (METHIONINE
REPRESSOR))		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		4 / 4 HIS B 387
ALA B 386
PHE B 385
GLY B 333
 CLA  B1226 (-4.1A)
CLA  B1226 ( 4.4A)
BCR  B4008 (-4.8A)
BCR  B4008 ( 4.6A)
 1.39A 1mj2D-6fosB:
undetectable		 1mj2D-6fosB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA141_0
(LYSOZYME C)		 6fos PHOTOSYSTEM I
REACTION CENTER
SUBUNIT II
(Cyanidioschyzon
merolae) 		4 / 6 GLY F  88
THR F  32
PRO F  33
SER F  37
 None
 0.89A 1n4fA-6fosF:
undetectable		 1n4fA-6fosF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA502_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		4 / 6 PHE B 607
ASN B 608
ILE B 510
GLY B 511
 None
 1.02A 1oniA-6fosB:
undetectable
1oniB-6fosB:
undetectable		 1oniA-6fosB:
undetectable
1oniB-6fosB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		4 / 6 PHE B 607
ASN B 608
ILE B 510
GLY B 511
 None
 1.04A 1oniD-6fosB:
undetectable
1oniF-6fosB:
undetectable		 1oniD-6fosB:
undetectable
1oniF-6fosB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		3 / 3 VAL B 280
ALA B 277
HIS B 274
 None
CLA  B1214 (-3.4A)
CLA  B1215 (-3.4A)
 0.74A 1q23G-6fosB:
undetectable		 1q23G-6fosB:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		3 / 3 VAL B 280
ALA B 277
HIS B 274
 None
CLA  B1214 (-3.4A)
CLA  B1215 (-3.4A)
 0.77A 1q23L-6fosB:
undetectable		 1q23L-6fosB:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_2
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		3 / 3 LEU A 359
HIS A 390
ILE A 393
 CLA  A1117 ( 4.7A)
CLA  A1127 (-4.0A)
CLA  A1127 (-4.3A)
 0.72A 1s9pB-6fosA:
undetectable		 1s9pB-6fosA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_2
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		3 / 3 LEU B 180
HIS B 275
ILE B 278
 CLA  B1210 (-3.6A)
CLA  B1215 (-4.0A)
CLA  B1215 ( 4.9A)
 0.69A 1s9pB-6fosB:
undetectable		 1s9pB-6fosB:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA502_1
(YKOF)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		4 / 6 ALA B 232
LEU B 253
ILE B 252
SER B 234
 None
 0.90A 1sbrA-6fosB:
undetectable
1sbrB-6fosB:
undetectable		 1sbrA-6fosB:
17.74
1sbrB-6fosB:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB503_1
(YKOF)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		4 / 7 PHE A 606
SER A 607
ILE A 745
ILE A 744
 None
 0.98A 1sbrB-6fosA:
undetectable		 1sbrB-6fosA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_1
(SUN PROTEIN)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		3 / 3 PRO B 546
ASP B 558
ASP B 550
 None
 0.58A 1sqfA-6fosB:
undetectable		 1sqfA-6fosB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_1
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		3 / 3 GLY A 336
GLU A 323
ASN A 418
 None
 0.69A 1zq9A-6fosA:
undetectable		 1zq9A-6fosA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA602_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		4 / 5 ILE A 136
LYS A 108
PRO A 381
ASP A 379
 CLA  A1106 (-3.4A)
None
None
None
 0.97A 2f7fA-6fosA:
undetectable		 2f7fA-6fosA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		5 / 12 GLN A 634
PHE A 529
VAL A 531
HIS A 532
ALA A 633
 None
None
None
CLA  A1135 (-4.3A)
None
 1.16A 2g70B-6fosA:
undetectable		 2g70B-6fosA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		5 / 12 GLN A 634
PHE A 529
VAL A 531
HIS A 532
ALA A 633
 None
None
None
CLA  A1135 (-4.3A)
None
 1.23A 2g72B-6fosA:
undetectable		 2g72B-6fosA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		5 / 8 MET A 681
PHE A 682
SER A 685
TRP A 690
ALA A 714
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
PQN  A2001 (-4.4A)
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
 0.90A 2o01A-6fosA:
39.6		 2o01A-6fosA:
82.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		5 / 8 MET A 681
PHE A 682
TRP A 690
ALA A 714
LEU A 715
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 1.12A 2o01A-6fosA:
39.6		 2o01A-6fosA:
82.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		5 / 8 TRP A  46
MET A 681
PHE A 682
TRP A 690
LEU A 715
 None
PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.7A)
 1.27A 2o01A-6fosA:
39.6		 2o01A-6fosA:
82.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		6 / 8 TRP B  22
MET B 660
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 None
PQN  B2002 ( 3.2A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 1.41A 2o01A-6fosB:
24.5		 2o01A-6fosB:
7.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		6 / 8 TRP B  22
MET B 660
PHE B 661
SER B 664
TRP B 669
ALA B 697
 None
PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
 1.11A 2o01A-6fosB:
24.5		 2o01A-6fosB:
7.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		6 / 8 TRP B  22
MET B 660
PHE B 661
TRP B 669
ALA B 697
LEU B 698
 None
PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 1.13A 2o01A-6fosB:
24.5		 2o01A-6fosB:
7.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		7 / 9 MET B 660
PHE B 661
SER B 664
ARG B 666
TRP B 669
ALA B 697
ALA B 703
 PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.4A)
 1.01A 2o01B-6fosB:
23.4		 2o01B-6fosB:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		8 / 9 PHE B 661
SER B 664
TRP B 665
ARG B 666
TRP B 669
ALA B 697
LEU B 698
ALA B 703
 PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
None
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 1.32A 2o01B-6fosB:
23.4		 2o01B-6fosB:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN1_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		4 / 6 LEU B 173
SER B 327
PHE B 330
ASP B 395
 None
None
BCR  B4008 (-4.5A)
None
 1.33A 2vn1B-6fosB:
undetectable		 2vn1B-6fosB:
17.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WSC_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		6 / 9 MET A 681
SER A 685
ARG A 687
TRP A 690
ALA A 714
GLY A 720
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.4A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
None
 0.85A 2wscA-6fosA:
13.9		 2wscA-6fosA:
82.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WSC_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		6 / 9 MET A 681
SER A 685
TRP A 690
ALA A 714
LEU A 715
GLY A 720
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.4A)
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
None
 0.68A 2wscA-6fosA:
13.9		 2wscA-6fosA:
82.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WSC_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		6 / 9 PHE A 682
SER A 685
TRP A 690
ALA A 714
LEU A 715
GLY A 720
 PQN  A2001 (-4.3A)
PQN  A2001 (-4.4A)
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
None
 0.64A 2wscA-6fosA:
13.9		 2wscA-6fosA:
82.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSC_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		5 / 9 MET B 660
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 PQN  B2002 ( 3.2A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.83A 2wscA-6fosB:
13.7		 2wscA-6fosB:
7.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSC_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		5 / 9 MET B 660
SER B 664
TRP B 669
ALA B 697
LEU B 698
 PQN  B2002 ( 3.2A)
CLA  B1023 (-4.5A)
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.73A 2wscA-6fosB:
13.7		 2wscA-6fosB:
7.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSC_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		5 / 9 PHE B 661
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 PQN  B2002 ( 4.3A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.86A 2wscA-6fosB:
13.7		 2wscA-6fosB:
7.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSC_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		5 / 9 PHE B 661
SER B 664
TRP B 669
ALA B 697
LEU B 698
 PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.77A 2wscA-6fosB:
13.7		 2wscA-6fosB:
7.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSC_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		7 / 10 TRP A  46
MET A 681
PHE A 682
ARG A 687
TRP A 690
ALA A 714
LEU A 715
 None
PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.79A 2wscB-6fosA:
12.3		 2wscB-6fosA:
6.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSC_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		7 / 10 TRP A  46
PHE A 682
SER A 685
ARG A 687
TRP A 690
ALA A 714
LEU A 715
 None
PQN  A2001 (-4.3A)
PQN  A2001 (-4.4A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.91A 2wscB-6fosA:
12.3		 2wscB-6fosA:
6.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSC_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		7 / 10 MET B 660
PHE B 661
SER B 664
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 1.00A 2wscB-6fosB:
12.2		 2wscB-6fosB:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSC_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		6 / 10 SER B 664
TRP B 665
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 CLA  B1023 (-4.5A)
None
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 1.34A 2wscB-6fosB:
12.2		 2wscB-6fosB:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSC_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		8 / 10 TRP B  22
MET B 660
PHE B 661
SER B 664
TRP B 669
ALA B 697
LEU B 698
ALA B 703
 None
PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 0.87A 2wscB-6fosB:
12.2		 2wscB-6fosB:
11.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WSE_A_PQNA1801_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		6 / 9 MET A 681
SER A 685
ARG A 687
TRP A 690
ALA A 714
GLY A 720
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.4A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
None
 0.85A 2wseA-6fosA:
14.0		 2wseA-6fosA:
82.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WSE_A_PQNA1801_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		6 / 9 MET A 681
SER A 685
TRP A 690
ALA A 714
LEU A 715
GLY A 720
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.4A)
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
None
 0.69A 2wseA-6fosA:
14.0		 2wseA-6fosA:
82.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WSE_A_PQNA1801_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		6 / 9 PHE A 682
SER A 685
TRP A 690
ALA A 714
LEU A 715
GLY A 720
 PQN  A2001 (-4.3A)
PQN  A2001 (-4.4A)
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
None
 0.66A 2wseA-6fosA:
14.0		 2wseA-6fosA:
82.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSE_A_PQNA1801_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		6 / 9 MET B 660
PHE B 661
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.88A 2wseA-6fosB:
11.4		 2wseA-6fosB:
7.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSE_A_PQNA1801_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		6 / 9 MET B 660
PHE B 661
SER B 664
TRP B 669
ALA B 697
LEU B 698
 PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.81A 2wseA-6fosB:
11.4		 2wseA-6fosB:
7.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSE_B_PQNB1774_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		7 / 10 TRP A  46
MET A 681
PHE A 682
ARG A 687
TRP A 690
ALA A 714
LEU A 715
 None
PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.79A 2wseB-6fosA:
12.6		 2wseB-6fosA:
6.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSE_B_PQNB1774_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		7 / 10 TRP A  46
PHE A 682
SER A 685
ARG A 687
TRP A 690
ALA A 714
LEU A 715
 None
PQN  A2001 (-4.3A)
PQN  A2001 (-4.4A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.91A 2wseB-6fosA:
12.6		 2wseB-6fosA:
6.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSE_B_PQNB1774_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		7 / 10 MET B 660
PHE B 661
SER B 664
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 1.00A 2wseB-6fosB:
12.1		 2wseB-6fosB:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSE_B_PQNB1774_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		6 / 10 SER B 664
TRP B 665
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 CLA  B1023 (-4.5A)
None
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 1.33A 2wseB-6fosB:
12.1		 2wseB-6fosB:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSE_B_PQNB1774_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		8 / 10 TRP B  22
MET B 660
PHE B 661
SER B 664
TRP B 669
ALA B 697
LEU B 698
ALA B 703
 None
PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 0.87A 2wseB-6fosB:
12.1		 2wseB-6fosB:
11.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WSF_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		6 / 9 MET A 681
SER A 685
ARG A 687
TRP A 690
ALA A 714
GLY A 720
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.4A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
None
 0.87A 2wsfA-6fosA:
25.2		 2wsfA-6fosA:
82.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WSF_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		6 / 9 MET A 681
SER A 685
TRP A 690
ALA A 714
LEU A 715
GLY A 720
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.4A)
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
None
 0.71A 2wsfA-6fosA:
25.2		 2wsfA-6fosA:
82.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WSF_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		6 / 9 PHE A 682
SER A 685
TRP A 690
ALA A 714
LEU A 715
GLY A 720
 PQN  A2001 (-4.3A)
PQN  A2001 (-4.4A)
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
None
 0.65A 2wsfA-6fosA:
25.2		 2wsfA-6fosA:
82.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		5 / 9 MET B 660
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 PQN  B2002 ( 3.2A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.82A 2wsfA-6fosB:
27.7		 2wsfA-6fosB:
7.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		5 / 9 MET B 660
SER B 664
TRP B 669
ALA B 697
LEU B 698
 PQN  B2002 ( 3.2A)
CLA  B1023 (-4.5A)
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.77A 2wsfA-6fosB:
27.7		 2wsfA-6fosB:
7.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		5 / 9 PHE B 661
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 PQN  B2002 ( 4.3A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.84A 2wsfA-6fosB:
27.7		 2wsfA-6fosB:
7.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		5 / 9 PHE B 661
SER B 664
TRP B 669
ALA B 697
LEU B 698
 PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.77A 2wsfA-6fosB:
27.7		 2wsfA-6fosB:
7.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		6 / 9 MET A 681
PHE A 682
ARG A 687
TRP A 690
ALA A 714
LEU A 715
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.78A 2wsfB-6fosA:
15.9		 2wsfB-6fosA:
6.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		6 / 9 PHE A 682
SER A 685
ARG A 687
TRP A 690
ALA A 714
LEU A 715
 PQN  A2001 (-4.3A)
PQN  A2001 (-4.4A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.92A 2wsfB-6fosA:
15.9		 2wsfB-6fosA:
6.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		7 / 9 MET B 660
PHE B 661
SER B 664
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.99A 2wsfB-6fosB:
11.7		 2wsfB-6fosB:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		7 / 9 MET B 660
PHE B 661
SER B 664
TRP B 669
ALA B 697
LEU B 698
ALA B 703
 PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 0.88A 2wsfB-6fosB:
11.7		 2wsfB-6fosB:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		6 / 9 SER B 664
TRP B 665
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 CLA  B1023 (-4.5A)
None
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 1.34A 2wsfB-6fosB:
11.7		 2wsfB-6fosB:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1162_1
(ALLERGEN ARG R 1)		 6fos PHOTOSYSTEM I
REACTION CENTER
SUBUNIT II
(Cyanidioschyzon
merolae) 		3 / 3 GLU F  47
HIS F  76
GLU F  44
 None
 0.83A 2x45B-6fosF:
undetectable		 2x45B-6fosF:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_E_GCSE710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		4 / 8 HIS A 605
ILE A 522
HIS A 532
ASP A 528
 CLA  A1135 (-4.3A)
CLA  A1135 ( 4.9A)
CLA  A1135 (-4.3A)
None
 0.98A 2xadA-6fosA:
undetectable		 2xadA-6fosA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_F_GCSF710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		4 / 8 HIS A 605
ILE A 522
HIS A 532
ASP A 528
 CLA  A1135 (-4.3A)
CLA  A1135 ( 4.9A)
CLA  A1135 (-4.3A)
None
 1.00A 2xadB-6fosA:
undetectable		 2xadB-6fosA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_G_GCSG710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		4 / 8 HIS A 605
ILE A 522
HIS A 532
ASP A 528
 CLA  A1135 (-4.3A)
CLA  A1135 ( 4.9A)
CLA  A1135 (-4.3A)
None
 1.00A 2xadC-6fosA:
undetectable		 2xadC-6fosA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_H_GCSH710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		4 / 8 HIS A 605
ILE A 522
HIS A 532
ASP A 528
 CLA  A1135 (-4.3A)
CLA  A1135 ( 4.9A)
CLA  A1135 (-4.3A)
None
 0.97A 2xadD-6fosA:
undetectable		 2xadD-6fosA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_D_TC9D1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		4 / 8 THR B  27
GLN B 702
ASP B  30
SER B  33
 None
None
CLA  B1226 (-3.4A)
None
 1.13A 2xytE-6fosB:
undetectable		 2xytE-6fosB:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		4 / 7 THR B  27
GLN B 702
ASP B  30
SER B  33
 None
None
CLA  B1226 (-3.4A)
None
 1.11A 2xytI-6fosB:
undetectable		 2xytI-6fosB:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		4 / 8 THR B  27
GLN B 702
ASP B  30
SER B  33
 None
None
CLA  B1226 (-3.4A)
None
 1.09A 2xz5C-6fosB:
undetectable
2xz5D-6fosB:
undetectable		 2xz5C-6fosB:
undetectable
2xz5D-6fosB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		4 / 8 THR B  27
GLN B 702
SER B  33
SER B 554
 None
 1.25A 2xz5C-6fosB:
undetectable
2xz5D-6fosB:
undetectable		 2xz5C-6fosB:
undetectable
2xz5D-6fosB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_D_SAMD603_0
(HYPOTHETICAL PROTEIN)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae;
Cyanidioschyzon
merolae) 		5 / 12 ILE A 559
GLY A 573
GLY A 575
ASP B 558
ASP A 572
 None
SF4  A3001 ( 4.0A)
None
None
None
 0.98A 2yvlD-6fosA:
undetectable		 2yvlD-6fosA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZI9_A_CL9A401_2
(DEOXYCYTIDINE KINASE)		 6fos PSAM
(Cyanidioschyzon
merolae) 		3 / 3 ASP O 118
PHE O 121
LEU O 125
 None
None
CLA  O1602 (-3.9A)
 0.30A 2zi9A-6fosO:
undetectable		 2zi9A-6fosO:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_A_SAMA298_0
(PUTATIVE
MODIFICATION
METHYLASE)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		5 / 12 SER B 664
GLY B 658
THR B 657
LEU B 708
VAL B 709
 CLA  B1023 (-4.5A)
None
CLA  B1239 ( 4.4A)
None
CLA  B1226 (-4.4A)
 1.13A 2zifA-6fosB:
undetectable		 2zifA-6fosB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_0
(PUTATIVE
MODIFICATION
METHYLASE)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		5 / 12 SER B 664
GLY B 658
THR B 657
LEU B 708
VAL B 709
 CLA  B1023 (-4.5A)
None
CLA  B1239 ( 4.4A)
None
CLA  B1226 (-4.4A)
 1.12A 2zifB-6fosB:
undetectable		 2zifB-6fosB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		4 / 6 ILE A 407
TYR A 408
LEU A 184
PHE A 187
 None
BCR  A4007 (-4.5A)
None
None
 1.06A 3adsA-6fosA:
undetectable		 3adsA-6fosA:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA607_1
(CHITINASE A)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		4 / 7 VAL B 604
SER B 598
THR B 509
LEU B 508
 None
 1.22A 3arrA-6fosB:
undetectable		 3arrA-6fosB:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID5_B_SAMB301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		5 / 11 GLY B 511
THR B 612
GLU B 454
ALA B 458
ILE B 510
 None
 1.34A 3id5B-6fosB:
undetectable		 3id5B-6fosB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID5_F_SAMF301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		5 / 11 GLY B 511
THR B 612
GLU B 454
ALA B 458
ILE B 510
 None
 1.34A 3id5F-6fosB:
undetectable		 3id5F-6fosB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		3 / 3 PRO B 354
PHE B 259
ALA B 360
 None
 0.68A 3itaD-6fosB:
undetectable		 3itaD-6fosB:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		3 / 3 ASN A 311
ASN A 189
GLU A 191
 None
 0.93A 3kpdC-6fosA:
undetectable		 3kpdC-6fosA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LW5_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		6 / 9 MET A 681
SER A 685
ARG A 687
TRP A 690
ALA A 714
GLY A 720
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.4A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
None
 0.84A 3lw5A-6fosA:
38.6		 3lw5A-6fosA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LW5_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		6 / 9 MET A 681
SER A 685
TRP A 690
ALA A 714
LEU A 715
GLY A 720
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.4A)
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
None
 0.68A 3lw5A-6fosA:
38.6		 3lw5A-6fosA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LW5_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		6 / 9 PHE A 682
SER A 685
TRP A 690
ALA A 714
LEU A 715
GLY A 720
 PQN  A2001 (-4.3A)
PQN  A2001 (-4.4A)
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
None
 0.61A 3lw5A-6fosA:
38.6		 3lw5A-6fosA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LW5_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		6 / 9 TRP A  46
MET A 681
SER A 685
TRP A 690
LEU A 715
GLY A 720
 None
PQN  A2001 ( 3.3A)
PQN  A2001 (-4.4A)
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.7A)
None
 1.41A 3lw5A-6fosA:
38.6		 3lw5A-6fosA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LW5_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		6 / 9 TRP A  46
PHE A 682
SER A 685
TRP A 690
LEU A 715
GLY A 720
 None
PQN  A2001 (-4.3A)
PQN  A2001 (-4.4A)
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.7A)
None
 1.39A 3lw5A-6fosA:
38.6		 3lw5A-6fosA:
80.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		6 / 9 MET B 660
PHE B 661
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.86A 3lw5A-6fosB:
28.5		 3lw5A-6fosB:
7.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		6 / 9 MET B 660
PHE B 661
SER B 664
TRP B 669
ALA B 697
LEU B 698
 PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.79A 3lw5A-6fosB:
28.5		 3lw5A-6fosB:
7.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		6 / 9 TRP B  22
MET B 660
PHE B 661
ARG B 666
TRP B 669
LEU B 698
 None
PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.6A)
 1.48A 3lw5A-6fosB:
28.5		 3lw5A-6fosB:
7.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		6 / 9 TRP B  22
MET B 660
PHE B 661
SER B 664
TRP B 669
LEU B 698
 None
PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
PQN  B2002 (-3.3A)
PQN  B2002 (-3.6A)
 1.41A 3lw5A-6fosB:
28.5		 3lw5A-6fosB:
7.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		6 / 10 MET A 681
PHE A 682
ARG A 687
TRP A 690
ALA A 714
LEU A 715
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.77A 3lw5B-6fosA:
11.4		 3lw5B-6fosA:
7.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		6 / 10 PHE A 682
SER A 685
ARG A 687
TRP A 690
ALA A 714
LEU A 715
 PQN  A2001 (-4.3A)
PQN  A2001 (-4.4A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.94A 3lw5B-6fosA:
11.4		 3lw5B-6fosA:
7.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		5 / 10 ILE B  21
MET B 660
PHE B 661
SER B 664
ALA B 703
 None
PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
PQN  B2002 (-3.4A)
 1.34A 3lw5B-6fosB:
11.5		 3lw5B-6fosB:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		8 / 10 ILE B  25
MET B 660
PHE B 661
SER B 664
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 CLA  B1201 ( 4.6A)
PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.96A 3lw5B-6fosB:
11.5		 3lw5B-6fosB:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		8 / 10 ILE B  25
MET B 660
PHE B 661
SER B 664
TRP B 669
ALA B 697
LEU B 698
ALA B 703
 CLA  B1201 ( 4.6A)
PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 0.86A 3lw5B-6fosB:
11.5		 3lw5B-6fosB:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		5 / 10 SER B 664
TRP B 665
ARG B 666
TRP B 669
ALA B 697
 CLA  B1023 (-4.5A)
None
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
 1.40A 3lw5B-6fosB:
11.5		 3lw5B-6fosB:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA206_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		4 / 4 ASP D  80
ARG D  73
THR D  70
ALA D  69
 None
 1.47A 3mbgA-6fosD:
undetectable		 3mbgA-6fosD:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PCQ_A_PQNA847_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		8 / 9 MET A 681
PHE A 682
GLY A 686
ARG A 687
TRP A 690
ALA A 714
LEU A 715
GLY A 720
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
PQN  A2001 ( 3.9A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
None
 0.80A 3pcqA-6fosA:
47.3		 3pcqA-6fosA:
81.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PCQ_A_PQNA847_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		8 / 9 MET A 681
PHE A 682
SER A 685
GLY A 686
ARG A 687
TRP A 690
ALA A 714
LEU A 715
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
PQN  A2001 (-4.4A)
PQN  A2001 ( 3.9A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.88A 3pcqA-6fosA:
47.3		 3pcqA-6fosA:
81.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_A_PQNA847_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		7 / 9 MET B 660
PHE B 661
SER B 664
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.84A 3pcqA-6fosB:
27.3		 3pcqA-6fosB:
6.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		8 / 11 TRP A  46
MET A 681
PHE A 682
ARG A 687
TRP A 690
ILE A 694
ALA A 714
LEU A 715
 None
PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
None
PQN  A2001 ( 3.2A)
None
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.70A 3pcqB-6fosA:
31.4		 3pcqB-6fosA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		8 / 11 TRP A  46
PHE A 682
SER A 685
ARG A 687
TRP A 690
ILE A 694
ALA A 714
LEU A 715
 None
PQN  A2001 (-4.3A)
PQN  A2001 (-4.4A)
None
PQN  A2001 ( 3.2A)
None
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.77A 3pcqB-6fosA:
31.4		 3pcqB-6fosA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		9 / 11 TRP B  22
MET B 660
PHE B 661
SER B 664
ARG B 666
TRP B 669
ILE B 673
ALA B 697
LEU B 698
 None
PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
None
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.76A 3pcqB-6fosB:
32.3		 3pcqB-6fosB:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		9 / 11 TRP B  22
MET B 660
PHE B 661
SER B 664
TRP B 669
ILE B 673
ALA B 697
LEU B 698
ALA B 703
 None
PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
PQN  B2002 (-3.3A)
None
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 0.64A 3pcqB-6fosB:
32.3		 3pcqB-6fosB:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		8 / 11 TRP B  22
PHE B 661
TRP B 665
ARG B 666
TRP B 669
ILE B 673
ALA B 697
LEU B 698
 None
PQN  B2002 ( 4.3A)
None
None
PQN  B2002 (-3.3A)
None
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 1.07A 3pcqB-6fosB:
32.3		 3pcqB-6fosB:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		8 / 11 TRP B  22
PHE B 661
TRP B 665
TRP B 669
ILE B 673
ALA B 697
LEU B 698
ALA B 703
 None
PQN  B2002 ( 4.3A)
None
PQN  B2002 (-3.3A)
None
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 0.96A 3pcqB-6fosB:
32.3		 3pcqB-6fosB:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PEO_F_CU9F301_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		4 / 6 THR A 158
TYR A  88
GLN A 154
ILE A 149
 CLA  A1112 (-3.7A)
None
CLA  A1114 (-4.4A)
None
 1.17A 3peoG-6fosA:
undetectable		 3peoG-6fosA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA601_0
(LACCASE-1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		4 / 5 HIS A 404
ILE A 407
HIS A 346
LEU A 349
 CLA  A1128 (-4.1A)
None
CLA  A1103 (-3.2A)
CLA  A1103 ( 3.6A)
 1.32A 3qpkA-6fosA:
undetectable		 3qpkA-6fosA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		5 / 12 PHE B 293
LEU B 173
GLY B 179
LEU B 180
ALA B 285
 None
None
CLA  B1210 ( 4.7A)
CLA  B1210 (-3.6A)
None
 1.13A 3tbgD-6fosB:
undetectable		 3tbgD-6fosB:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_1
(HIV-1 PROTEASE)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		5 / 10 ASP B 236
GLY B 249
ALA B 248
GLY B 202
ILE B 197
 None
 0.91A 3ttpA-6fosB:
undetectable		 3ttpA-6fosB:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_1
(METHYLTRANSFERASE
WBDD)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		3 / 3 GLN D  79
ASP D  99
GLN D  93
 None
 0.87A 4aztA-6fosD:
undetectable		 4aztA-6fosD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_C_SAMC800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		5 / 11 ILE B 278
GLY B 182
GLY B 190
HIS B 274
TRP B 188
 CLA  B1215 ( 4.9A)
None
None
CLA  B1215 (-3.4A)
CLA  B1215 (-4.0A)
 1.26A 4e47C-6fosB:
undetectable		 4e47C-6fosB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		4 / 7 ILE B 127
ARG B 128
VAL B  78
TRP B  77
 None
 1.32A 4f4dA-6fosB:
undetectable		 4f4dA-6fosB:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FE1_A_PQNA846_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX
(Cyanidioschyzon
merolae) 		7 / 10 MET A 681
PHE A 682
ARG A 687
TRP A 690
ALA A 714
LEU A 715
ALA J  14
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
PQN  A2001 ( 4.0A)
 0.79A 4fe1A-6fosA:
47.0
4fe1J-6fosA:
undetectable		 4fe1A-6fosA:
81.25
4fe1J-6fosA:
18.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FE1_A_PQNA846_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX
(Cyanidioschyzon
merolae) 		7 / 10 MET A 681
PHE A 682
TRP A 690
ALA A 714
LEU A 715
GLY A 720
ALA J  14
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
None
PQN  A2001 ( 4.0A)
 0.59A 4fe1A-6fosA:
47.0
4fe1J-6fosA:
undetectable		 4fe1A-6fosA:
81.25
4fe1J-6fosA:
18.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FE1_A_PQNA846_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX
(Cyanidioschyzon
merolae) 		6 / 10 MET A 681
PHE A 682
TRP A 690
LEU A 715
GLY A 720
ALA J  10
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.7A)
None
CLA  A1101 ( 4.6A)
 1.06A 4fe1A-6fosA:
47.0
4fe1J-6fosA:
undetectable		 4fe1A-6fosA:
81.25
4fe1J-6fosA:
18.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FE1_A_PQNA846_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX
(Cyanidioschyzon
merolae) 		7 / 10 MET A 681
SER A 685
ARG A 687
TRP A 690
ALA A 714
LEU A 715
ALA J  14
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.4A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
PQN  A2001 ( 4.0A)
 1.02A 4fe1A-6fosA:
47.0
4fe1J-6fosA:
undetectable		 4fe1A-6fosA:
81.25
4fe1J-6fosA:
18.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FE1_A_PQNA846_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX
(Cyanidioschyzon
merolae) 		5 / 10 MET A 681
SER A 685
TRP A 690
LEU A 715
ALA J  10
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.4A)
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.7A)
CLA  A1101 ( 4.6A)
 1.34A 4fe1A-6fosA:
47.0
4fe1J-6fosA:
undetectable		 4fe1A-6fosA:
81.25
4fe1J-6fosA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_A_PQNA846_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		7 / 10 MET B 660
PHE B 661
SER B 664
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.87A 4fe1A-6fosB:
27.2
4fe1J-6fosB:
undetectable		 4fe1A-6fosB:
6.81
4fe1J-6fosB:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_B_PQNB840_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		6 / 9 MET A 681
ARG A 687
TRP A 690
ILE A 694
ALA A 714
LEU A 715
 PQN  A2001 ( 3.3A)
None
PQN  A2001 ( 3.2A)
None
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.77A 4fe1B-6fosA:
31.2		 4fe1B-6fosA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_B_PQNB840_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		6 / 9 SER A 685
ARG A 687
TRP A 690
ILE A 694
ALA A 714
LEU A 715
 PQN  A2001 (-4.4A)
None
PQN  A2001 ( 3.2A)
None
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.91A 4fe1B-6fosA:
31.2		 4fe1B-6fosA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_B_PQNB840_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		8 / 9 MET B 660
SER B 664
ARG B 666
TRP B 669
ILE B 673
ALA B 697
LEU B 698
ALA B 703
 PQN  B2002 ( 3.2A)
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
None
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 0.87A 4fe1B-6fosB:
32.3		 4fe1B-6fosB:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_B_PQNB840_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		7 / 9 TRP B 665
ARG B 666
TRP B 669
ILE B 673
ALA B 697
LEU B 698
ALA B 703
 None
None
PQN  B2002 (-3.3A)
None
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 1.14A 4fe1B-6fosB:
32.3		 4fe1B-6fosB:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		4 / 6 ILE A 733
THR A 736
VAL A 725
SER A 600
 CLA  A1126 ( 3.8A)
CLA  A1011 (-3.1A)
None
CLA  A1011 ( 4.3A)
 1.09A 4iaqA-6fosA:
2.9		 4iaqA-6fosA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_C_SAMC401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		5 / 11 ILE B 278
GLY B 182
GLY B 190
HIS B 274
TRP B 188
 CLA  B1215 ( 4.9A)
None
None
CLA  B1215 (-3.4A)
CLA  B1215 (-4.0A)
 1.25A 4jdsC-6fosB:
undetectable		 4jdsC-6fosB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLG_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		5 / 12 ILE B 278
GLY B 182
GLY B 190
HIS B 274
TRP B 188
 CLA  B1215 ( 4.9A)
None
None
CLA  B1215 (-3.4A)
CLA  B1215 (-4.0A)
 1.20A 4jlgA-6fosB:
undetectable		 4jlgA-6fosB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMM_A_CHDA503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		4 / 7 ARG B 128
SER B 116
VAL B  78
TRP B  77
 None
 1.01A 4kmmA-6fosB:
undetectable		 4kmmA-6fosB:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KT0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		8 / 11 MET A 681
PHE A 682
SER A 685
GLY A 686
ARG A 687
TRP A 690
ALA A 714
LEU A 715
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
PQN  A2001 (-4.4A)
PQN  A2001 ( 3.9A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.88A 4kt0A-6fosA:
46.8
4kt0J-6fosA:
1.4		 4kt0A-6fosA:
69.23
4kt0J-6fosA:
17.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KT0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX
(Cyanidioschyzon
merolae) 		9 / 11 MET A 681
PHE A 682
GLY A 686
ARG A 687
TRP A 690
ALA A 714
LEU A 715
GLY A 720
LEU J  18
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
PQN  A2001 ( 3.9A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
None
None
 0.82A 4kt0A-6fosA:
46.8
4kt0J-6fosA:
1.4		 4kt0A-6fosA:
69.23
4kt0J-6fosA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		7 / 11 MET B 660
PHE B 661
SER B 664
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.89A 4kt0A-6fosB:
27.3
4kt0J-6fosB:
undetectable		 4kt0A-6fosB:
19.42
4kt0J-6fosB:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		6 / 9 MET A 681
SER A 685
ARG A 687
TRP A 690
ALA A 714
LEU A 715
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.4A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.91A 4kt0B-6fosA:
35.2		 4kt0B-6fosA:
8.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		6 / 9 TRP A  46
SER A 685
ARG A 687
TRP A 690
ALA A 714
LEU A 715
 None
PQN  A2001 (-4.4A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.81A 4kt0B-6fosA:
35.2		 4kt0B-6fosA:
8.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		8 / 9 TRP B  22
MET B 660
SER B 664
ARG B 666
TRP B 669
ALA B 697
LEU B 698
ALA B 703
 None
PQN  B2002 ( 3.2A)
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 0.82A 4kt0B-6fosB:
32.8		 4kt0B-6fosB:
10.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		8 / 9 TRP B  22
SER B 664
TRP B 665
ARG B 666
TRP B 669
ALA B 697
LEU B 698
ALA B 703
 None
CLA  B1023 (-4.5A)
None
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 1.05A 4kt0B-6fosB:
32.8		 4kt0B-6fosB:
10.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		8 / 11 MET A 681
PHE A 682
SER A 685
GLY A 686
ARG A 687
TRP A 690
ALA A 714
LEU A 715
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
PQN  A2001 (-4.4A)
PQN  A2001 ( 3.9A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.85A 4l6v1-6fosA:
40.0
4l6v6-6fosA:
2.3		 4l6v1-6fosA:
69.23
4l6v6-6fosA:
18.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		8 / 11 TRP A  46
PHE A 682
SER A 685
GLY A 686
ARG A 687
TRP A 690
ALA A 714
LEU A 715
 None
PQN  A2001 (-4.3A)
PQN  A2001 (-4.4A)
PQN  A2001 ( 3.9A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.82A 4l6v1-6fosA:
40.0
4l6v6-6fosA:
2.3		 4l6v1-6fosA:
69.23
4l6v6-6fosA:
18.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX
(Cyanidioschyzon
merolae) 		9 / 11 MET A 681
PHE A 682
GLY A 686
ARG A 687
TRP A 690
ALA A 714
LEU A 715
GLY A 720
ALA J  14
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
PQN  A2001 ( 3.9A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
None
PQN  A2001 ( 4.0A)
 0.85A 4l6v1-6fosA:
40.0
4l6v6-6fosA:
2.3		 4l6v1-6fosA:
69.23
4l6v6-6fosA:
18.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX
(Cyanidioschyzon
merolae) 		8 / 11 MET A 681
PHE A 682
GLY A 686
TRP A 690
ALA A 714
LEU A 715
GLY A 720
ALA J  10
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
PQN  A2001 ( 3.9A)
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
None
CLA  A1101 ( 4.6A)
 1.41A 4l6v1-6fosA:
40.0
4l6v6-6fosA:
2.3		 4l6v1-6fosA:
69.23
4l6v6-6fosA:
18.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX
(Cyanidioschyzon
merolae) 		9 / 11 TRP A  46
PHE A 682
GLY A 686
ARG A 687
TRP A 690
ALA A 714
LEU A 715
GLY A 720
ALA J  14
 None
PQN  A2001 (-4.3A)
PQN  A2001 ( 3.9A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
None
PQN  A2001 ( 4.0A)
 0.96A 4l6v1-6fosA:
40.0
4l6v6-6fosA:
2.3		 4l6v1-6fosA:
69.23
4l6v6-6fosA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		8 / 11 TRP B  22
MET B 660
PHE B 661
SER B 664
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 None
PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.90A 4l6v1-6fosB:
27.2
4l6v6-6fosB:
1.4		 4l6v1-6fosB:
19.42
4l6v6-6fosB:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_2_PQN22002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		5 / 9 MET A 681
ARG A 687
TRP A 690
ALA A 714
LEU A 715
 PQN  A2001 ( 3.3A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.73A 4l6v2-6fosA:
34.7		 4l6v2-6fosA:
8.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_2_PQN22002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		6 / 9 TRP A  46
SER A 685
ARG A 687
TRP A 690
ALA A 714
LEU A 715
 None
PQN  A2001 (-4.4A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.80A 4l6v2-6fosA:
34.7		 4l6v2-6fosA:
8.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_2_PQN22002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		6 / 9 MET B 660
SER B 664
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 PQN  B2002 ( 3.2A)
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.88A 4l6v2-6fosB:
32.7		 4l6v2-6fosB:
10.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_2_PQN22002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		6 / 9 MET B 660
SER B 664
TRP B 669
ALA B 697
LEU B 698
ALA B 703
 PQN  B2002 ( 3.2A)
CLA  B1023 (-4.5A)
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 0.73A 4l6v2-6fosB:
32.7		 4l6v2-6fosB:
10.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_2_PQN22002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		7 / 9 TRP B  22
SER B 664
TRP B 665
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 None
CLA  B1023 (-4.5A)
None
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 1.00A 4l6v2-6fosB:
32.7		 4l6v2-6fosB:
10.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_2_PQN22002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		7 / 9 TRP B  22
SER B 664
TRP B 665
TRP B 669
ALA B 697
LEU B 698
ALA B 703
 None
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 0.82A 4l6v2-6fosB:
32.7		 4l6v2-6fosB:
10.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4L6V_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		7 / 9 TRP A  46
MET A 681
PHE A 682
SER A 685
TRP A 690
ALA A 714
LEU A 715
 None
PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
PQN  A2001 (-4.4A)
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.86A 4l6va-6fosA:
40.0
4l6vf-6fosA:
1.2		 4l6va-6fosA:
69.23
4l6vf-6fosA:
18.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4L6V_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX
(Cyanidioschyzon
merolae) 		8 / 9 TRP A  46
MET A 681
PHE A 682
TRP A 690
ALA A 714
LEU A 715
GLY A 720
ALA J  14
 None
PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
None
PQN  A2001 ( 4.0A)
 1.02A 4l6va-6fosA:
40.0
4l6vf-6fosA:
1.2		 4l6va-6fosA:
69.23
4l6vf-6fosA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		7 / 9 TRP B  22
MET B 660
PHE B 661
SER B 664
TRP B 669
ALA B 697
LEU B 698
 None
PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.67A 4l6va-6fosB:
27.2
4l6vf-6fosB:
undetectable		 4l6va-6fosB:
19.42
4l6vf-6fosB:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		5 / 9 MET A 681
ARG A 687
TRP A 690
ALA A 714
LEU A 715
 PQN  A2001 ( 3.3A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.71A 4l6vB-6fosA:
31.7		 4l6vB-6fosA:
8.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		6 / 9 TRP A  46
SER A 685
ARG A 687
TRP A 690
ALA A 714
LEU A 715
 None
PQN  A2001 (-4.4A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.81A 4l6vB-6fosA:
31.7		 4l6vB-6fosA:
8.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		6 / 9 MET B 660
SER B 664
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 PQN  B2002 ( 3.2A)
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.84A 4l6vB-6fosB:
32.7		 4l6vB-6fosB:
10.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		6 / 9 MET B 660
SER B 664
TRP B 669
ALA B 697
LEU B 698
ALA B 703
 PQN  B2002 ( 3.2A)
CLA  B1023 (-4.5A)
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 0.70A 4l6vB-6fosB:
32.7		 4l6vB-6fosB:
10.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		7 / 9 TRP B  22
SER B 664
TRP B 665
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 None
CLA  B1023 (-4.5A)
None
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.99A 4l6vB-6fosB:
32.7		 4l6vB-6fosB:
10.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		7 / 9 TRP B  22
SER B 664
TRP B 665
TRP B 669
ALA B 697
LEU B 698
ALA B 703
 None
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 0.84A 4l6vB-6fosB:
32.7		 4l6vB-6fosB:
10.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A303_1
(ANCESTRAL STEROID
RECEPTOR 2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		5 / 9 THR A 512
ALA A 518
GLN A 142
TYR A 375
THR A 282
 None
 1.32A 4ltwA-6fosA:
undetectable		 4ltwA-6fosA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A303_1
(ANCESTRAL STEROID
RECEPTOR 2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		5 / 9 THR A 512
LEU A 278
ALA A 518
GLN A 142
TYR A 375
 None
 1.23A 4ltwA-6fosA:
undetectable		 4ltwA-6fosA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_A_ASCA303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
IRON-SULFUR CENTER
SUBUNIT VII
(Cyanidioschyzon
merolae;
Cyanidioschyzon
merolae) 		4 / 7 PHE E  40
TYR E  45
ASN A 702
ARG A 713
 None
 1.26A 4o7gA-6fosE:
undetectable
4o7gB-6fosE:
undetectable		 4o7gA-6fosE:
undetectable
4o7gB-6fosE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA304_1
(TYROSINASE)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		4 / 5 ASN A 455
LEU A 451
HIS A 454
THR A 471
 None
CLA  A1132 (-4.5A)
CLA  A1132 (-3.6A)
None
 1.42A 4p6sA-6fosA:
undetectable		 4p6sA-6fosA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_E_PARE500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		5 / 12 PHE A 740
SER A 600
PHE A 604
TYR A 728
GLY A 732
 None
CLA  A1011 ( 4.3A)
CLA  A1011 (-4.6A)
None
CLA  A1011 (-3.9A)
 1.31A 4qb9E-6fosA:
undetectable		 4qb9E-6fosA:
10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		5 / 12 GLY B 383
GLY B 333
ILE B 381
ILE B 390
ALA B 386
 CLA  B1226 (-3.4A)
BCR  B4008 ( 4.6A)
CLA  B1222 (-3.7A)
CLA  B1226 (-4.3A)
CLA  B1226 ( 4.4A)
 1.07A 4qtuD-6fosB:
undetectable		 4qtuD-6fosB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_D_ACTD201_0
(RETINOL-BINDING
PROTEIN 2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		3 / 3 ASP D  80
HIS D  96
LYS D  82
 None
 0.82A 4qzuD-6fosD:
undetectable		 4qzuD-6fosD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RKU_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		6 / 9 TRP A  46
MET A 681
ARG A 687
TRP A 690
ALA A 714
LEU A 715
 None
PQN  A2001 ( 3.3A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.64A 4rkuB-6fosA:
32.6		 4rkuB-6fosA:
7.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RKU_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		6 / 9 TRP A  46
SER A 685
ARG A 687
TRP A 690
ALA A 714
LEU A 715
 None
PQN  A2001 (-4.4A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.84A 4rkuB-6fosA:
32.6		 4rkuB-6fosA:
7.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RKU_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		7 / 9 TRP B  22
MET B 660
SER B 664
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 None
PQN  B2002 ( 3.2A)
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.82A 4rkuB-6fosB:
32.8		 4rkuB-6fosB:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RKU_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		7 / 9 TRP B  22
MET B 660
SER B 664
TRP B 669
ALA B 697
LEU B 698
ALA B 703
 None
PQN  B2002 ( 3.2A)
CLA  B1023 (-4.5A)
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 0.68A 4rkuB-6fosB:
32.8		 4rkuB-6fosB:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RKU_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		7 / 9 TRP B  22
SER B 664
TRP B 665
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 None
CLA  B1023 (-4.5A)
None
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 1.08A 4rkuB-6fosB:
32.8		 4rkuB-6fosB:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RKU_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		7 / 9 TRP B  22
SER B 664
TRP B 665
TRP B 669
ALA B 697
LEU B 698
ALA B 703
 None
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 0.95A 4rkuB-6fosB:
32.8		 4rkuB-6fosB:
11.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XK8_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		7 / 7 MET A 681
PHE A 682
SER A 685
ARG A 687
TRP A 690
ALA A 714
LEU A 715
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
PQN  A2001 (-4.4A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.91A 4xk8A-6fosA:
42.2		 4xk8A-6fosA:
82.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		7 / 7 MET B 660
PHE B 661
SER B 664
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.83A 4xk8A-6fosB:
27.3		 4xk8A-6fosB:
7.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XK8_A_PQNA845_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		5 / 8 MET A 681
PHE A 682
ARG A 687
TRP A 690
ALA A 714
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
 0.70A 4xk8a-6fosA:
42.2		 4xk8a-6fosA:
82.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XK8_A_PQNA845_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		6 / 8 MET A 681
PHE A 682
TRP A 690
ALA A 714
LEU A 715
GLY A 720
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
None
 0.58A 4xk8a-6fosA:
42.2		 4xk8a-6fosA:
82.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XK8_A_PQNA845_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		4 / 8 SER A 685
ARG A 687
TRP A 690
ALA A 714
 PQN  A2001 (-4.4A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
 0.89A 4xk8a-6fosA:
42.2		 4xk8a-6fosA:
82.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA845_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		7 / 8 MET B 660
PHE B 661
SER B 664
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.82A 4xk8a-6fosB:
27.3		 4xk8a-6fosB:
7.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		6 / 10 MET A 681
ARG A 687
TRP A 690
ILE A 694
ALA A 714
LEU A 715
 PQN  A2001 ( 3.3A)
None
PQN  A2001 ( 3.2A)
None
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.71A 4xk8B-6fosA:
35.2		 4xk8B-6fosA:
7.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		7 / 10 TRP A  46
SER A 685
ARG A 687
TRP A 690
ILE A 694
ALA A 714
LEU A 715
 None
PQN  A2001 (-4.4A)
None
PQN  A2001 ( 3.2A)
None
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.79A 4xk8B-6fosA:
35.2		 4xk8B-6fosA:
7.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		8 / 10 MET B 660
SER B 664
ARG B 666
TRP B 669
ILE B 673
ALA B 697
LEU B 698
ALA B 703
 PQN  B2002 ( 3.2A)
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
None
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 0.87A 4xk8B-6fosB:
32.7		 4xk8B-6fosB:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		8 / 10 TRP B  22
SER B 664
ARG B 666
TRP B 669
ILE B 673
ALA B 697
LEU B 698
ALA B 703
 None
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
None
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 0.80A 4xk8B-6fosB:
32.7		 4xk8B-6fosB:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		8 / 10 TRP B  22
TRP B 665
ARG B 666
TRP B 669
ILE B 673
ALA B 697
LEU B 698
ALA B 703
 None
None
None
PQN  B2002 (-3.3A)
None
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 1.11A 4xk8B-6fosB:
32.7		 4xk8B-6fosB:
10.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y28_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		7 / 9 MET A 681
PHE A 682
ARG A 687
TRP A 690
ALA A 714
LEU A 715
GLY A 720
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
None
 0.76A 4y28A-6fosA:
42.8
4y28J-6fosA:
undetectable		 4y28A-6fosA:
81.25
4y28J-6fosA:
21.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y28_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		7 / 9 MET A 681
PHE A 682
SER A 685
ARG A 687
TRP A 690
ALA A 714
LEU A 715
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
PQN  A2001 (-4.4A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.87A 4y28A-6fosA:
42.8
4y28J-6fosA:
undetectable		 4y28A-6fosA:
81.25
4y28J-6fosA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y28_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		7 / 9 MET B 660
PHE B 661
SER B 664
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.83A 4y28A-6fosB:
28.0
4y28J-6fosB:
undetectable		 4y28A-6fosB:
7.16
4y28J-6fosB:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y28_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		6 / 9 TRP A  46
MET A 681
ARG A 687
TRP A 690
ALA A 714
LEU A 715
 None
PQN  A2001 ( 3.3A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.74A 4y28B-6fosA:
31.8		 4y28B-6fosA:
6.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y28_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		6 / 9 TRP A  46
SER A 685
ARG A 687
TRP A 690
ALA A 714
LEU A 715
 None
PQN  A2001 (-4.4A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.81A 4y28B-6fosA:
31.8		 4y28B-6fosA:
6.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y28_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		8 / 9 TRP B  22
MET B 660
SER B 664
ARG B 666
TRP B 669
ALA B 697
LEU B 698
ALA B 703
 None
PQN  B2002 ( 3.2A)
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 0.83A 4y28B-6fosB:
32.7		 4y28B-6fosB:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y28_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		7 / 9 TRP B  22
TRP B 665
ARG B 666
TRP B 669
ALA B 697
LEU B 698
ALA B 703
 None
None
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 1.14A 4y28B-6fosB:
32.7		 4y28B-6fosB:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_B_DESB600_1
(ESTROGEN RECEPTOR)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		5 / 11 ALA A 347
LEU A 337
LEU A 341
LEU A 423
MET A 426
 BCR  A4007 ( 4.9A)
CLA  A1122 ( 4.4A)
CLA  A1123 (-3.8A)
BCR  A4007 ( 4.7A)
CLA  A1129 (-3.4A)
 1.36A 4zn7B-6fosA:
1.9		 4zn7B-6fosA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDP_H_EVPH2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		4 / 6 SER A 716
GLY A 573
ASP A 572
GLY B 559
 None
SF4  A3001 ( 4.0A)
None
None
 0.72A 5cdpA-6fosA:
undetectable
5cdpB-6fosA:
undetectable		 5cdpA-6fosA:
9.84
5cdpB-6fosA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		3 / 3 GLU B 497
TRP B 495
ASN B 504
 None
 1.14A 5dv4A-6fosB:
undetectable		 5dv4A-6fosB:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HUA_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		5 / 11 ASP A 572
ARG A 576
ILE A 717
PHE A 569
LEU A 565
 None
 1.47A 5huaA-6fosA:
undetectable		 5huaA-6fosA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		3 / 3 VAL B 588
SER B 344
MET B 350
 None
CLA  B1222 (-3.3A)
None
 0.80A 5ikqA-6fosB:
0.0		 5ikqA-6fosB:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_B_ACTB713_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		3 / 3 GLY B 316
GLN B 322
LYS B 300
 None
 0.83A 5imsB-6fosB:
undetectable		 5imsB-6fosB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 6fos PHOTOSYSTEM I
REACTION CENTER
SUBUNIT X
(Cyanidioschyzon
merolae) 		4 / 6 ILE K  45
GLY K  20
ASN K  17
ILE K  46
 None
 0.98A 5j4nB-6fosK:
undetectable		 5j4nB-6fosK:
8.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L8R_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		8 / 9 MET A 681
PHE A 682
GLY A 686
ARG A 687
TRP A 690
ALA A 714
LEU A 715
GLY A 720
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
PQN  A2001 ( 3.9A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
None
 0.78A 5l8rA-6fosA:
40.6		 5l8rA-6fosA:
82.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L8R_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		8 / 9 MET A 681
PHE A 682
SER A 685
GLY A 686
ARG A 687
TRP A 690
ALA A 714
LEU A 715
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
PQN  A2001 (-4.4A)
PQN  A2001 ( 3.9A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.84A 5l8rA-6fosA:
40.6		 5l8rA-6fosA:
82.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8R_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		7 / 9 MET B 660
PHE B 661
SER B 664
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.85A 5l8rA-6fosB:
28.3		 5l8rA-6fosB:
7.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8R_B_PQNB841_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		7 / 9 TRP A  46
MET A 681
SER A 685
ARG A 687
TRP A 690
ALA A 714
LEU A 715
 None
PQN  A2001 ( 3.3A)
PQN  A2001 (-4.4A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.89A 5l8rB-6fosA:
31.9		 5l8rB-6fosA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8R_B_PQNB841_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		7 / 9 TRP B  22
MET B 660
SER B 664
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 None
PQN  B2002 ( 3.2A)
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.82A 5l8rB-6fosB:
32.7		 5l8rB-6fosB:
9.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8R_B_PQNB841_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		7 / 9 TRP B  22
MET B 660
SER B 664
TRP B 669
ALA B 697
LEU B 698
ALA B 703
 None
PQN  B2002 ( 3.2A)
CLA  B1023 (-4.5A)
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 0.67A 5l8rB-6fosB:
32.7		 5l8rB-6fosB:
9.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8R_B_PQNB841_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		6 / 9 TRP B  22
TRP B 665
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 None
None
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 1.16A 5l8rB-6fosB:
32.7		 5l8rB-6fosB:
9.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8R_B_PQNB841_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		6 / 9 TRP B  22
TRP B 665
TRP B 669
ALA B 697
LEU B 698
ALA B 703
 None
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 1.03A 5l8rB-6fosB:
32.7		 5l8rB-6fosB:
9.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		3 / 3 SER B 340
SER B 344
PHE B 385
 None
CLA  B1222 (-3.3A)
BCR  B4008 (-4.8A)
 0.93A 5mugA-6fosB:
undetectable		 5mugA-6fosB:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OY0_1_PQN1842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		7 / 10 MET A 681
PHE A 682
SER A 685
ARG A 687
TRP A 690
ALA A 714
LEU A 715
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
PQN  A2001 (-4.4A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.83A 5oy01-6fosA:
41.0
5oy07-6fosA:
1.6		 5oy01-6fosA:
73.75
5oy07-6fosA:
17.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OY0_1_PQN1842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX
(Cyanidioschyzon
merolae) 		8 / 10 MET A 681
PHE A 682
ARG A 687
TRP A 690
ALA A 714
LEU A 715
GLY A 720
LEU J  18
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
None
None
 0.76A 5oy01-6fosA:
41.0
5oy07-6fosA:
1.6		 5oy01-6fosA:
73.75
5oy07-6fosA:
17.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OY0_1_PQN1842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		7 / 10 MET B 660
PHE B 661
SER B 664
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.76A 5oy01-6fosB:
27.7
5oy07-6fosB:
undetectable		 5oy01-6fosB:
33.33
5oy07-6fosB:
14.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OY0_2_PQN2843_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		9 / 12 TRP A  46
MET A 681
PHE A 682
SER A 685
ARG A 687
TRP A 690
ILE A 694
ALA A 714
LEU A 715
 None
PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
PQN  A2001 (-4.4A)
None
PQN  A2001 ( 3.2A)
None
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.83A 5oy02-6fosA:
31.9		 5oy02-6fosA:
34.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OY0_2_PQN2843_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		11 / 12 TRP B  22
ILE B  25
MET B 660
PHE B 661
SER B 664
ARG B 666
TRP B 669
ILE B 673
ALA B 697
LEU B 698
ALA B 703
 None
CLA  B1201 ( 4.6A)
PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
None
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 0.74A 5oy02-6fosB:
32.6		 5oy02-6fosB:
85.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OY0_2_PQN2843_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		10 / 12 TRP B  22
ILE B  25
PHE B 661
TRP B 665
ARG B 666
TRP B 669
ILE B 673
ALA B 697
LEU B 698
ALA B 703
 None
CLA  B1201 ( 4.6A)
PQN  B2002 ( 4.3A)
None
None
PQN  B2002 (-3.3A)
None
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 1.04A 5oy02-6fosB:
32.6		 5oy02-6fosB:
85.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OY0_B_PQNB1844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		7 / 10 MET A 681
PHE A 682
SER A 685
ARG A 687
TRP A 690
ILE A 694
ALA A 714
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
PQN  A2001 (-4.4A)
None
PQN  A2001 ( 3.2A)
None
PQN  A2001 (-3.2A)
 0.81A 5oy0b-6fosA:
32.1		 5oy0b-6fosA:
33.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OY0_B_PQNB1844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		7 / 10 MET A 681
PHE A 682
SER A 685
TRP A 690
ILE A 694
ALA A 714
LEU A 715
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
PQN  A2001 (-4.4A)
PQN  A2001 ( 3.2A)
None
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.71A 5oy0b-6fosA:
32.1		 5oy0b-6fosA:
33.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OY0_B_PQNB1844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		9 / 10 MET B 660
PHE B 661
SER B 664
ARG B 666
TRP B 669
ILE B 673
ALA B 697
LEU B 698
ALA B 703
 PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
None
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 0.66A 5oy0b-6fosB:
32.7		 5oy0b-6fosB:
85.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OY0_B_PQNB1844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		9 / 10 PHE B 661
SER B 664
TRP B 665
ARG B 666
TRP B 669
ILE B 673
ALA B 697
LEU B 698
ALA B 703
 PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
None
None
PQN  B2002 (-3.3A)
None
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 0.96A 5oy0b-6fosB:
32.7		 5oy0b-6fosB:
85.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		4 / 9 LYS A  40
ILE A 710
ILE A  45
LEU A  48
 None
None
CLA  A1101 ( 4.3A)
CLA  A1101 ( 4.4A)
 0.79A 5vkqB-6fosA:
2.6
5vkqC-6fosA:
2.6		 5vkqB-6fosA:
undetectable
5vkqC-6fosA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZGB_B_PQNB844_1
(PSAB)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		7 / 9 ILE A  45
TRP A  46
MET A 681
ARG A 687
TRP A 690
ALA A 714
LEU A 715
 CLA  A1101 ( 4.3A)
None
PQN  A2001 ( 3.3A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 1.41A 5zgbB-6fosA:
34.9		 5zgbB-6fosA:
36.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZGB_B_PQNB844_1
(PSAB)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		7 / 9 ILE B  21
TRP B  22
MET B 660
ARG B 666
ALA B 697
LEU B 698
ALA B 703
 None
None
PQN  B2002 ( 3.2A)
None
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 0.79A 5zgbB-6fosB:
31.7		 5zgbB-6fosB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZGB_B_PQNB844_1
(PSAB)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		7 / 9 ILE B  21
TRP B  22
MET B 660
TRP B 669
ALA B 697
LEU B 698
ALA B 703
 None
None
PQN  B2002 ( 3.2A)
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 1.19A 5zgbB-6fosB:
31.7		 5zgbB-6fosB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZGB_B_PQNB844_1
(PSAB)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		7 / 9 ILE B  21
TRP B  22
TRP B 665
ARG B 666
ALA B 697
LEU B 698
ALA B 703
 None
None
None
None
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 1.09A 5zgbB-6fosB:
31.7		 5zgbB-6fosB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZGH_B_PQNB843_1
(PSAB)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		7 / 9 ILE A  45
TRP A  46
MET A 681
ARG A 687
TRP A 690
ALA A 714
LEU A 715
 CLA  A1101 ( 4.3A)
None
PQN  A2001 ( 3.3A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 1.41A 5zghB-6fosA:
31.6		 5zghB-6fosA:
36.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZGH_B_PQNB843_1
(PSAB)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		6 / 9 ILE B  21
MET B 660
ARG B 666
ALA B 697
LEU B 698
ALA B 703
 None
PQN  B2002 ( 3.2A)
None
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 0.81A 5zghB-6fosB:
31.6		 5zghB-6fosB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZGH_B_PQNB843_1
(PSAB)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		7 / 9 ILE B  21
TRP B  22
MET B 660
TRP B 669
ALA B 697
LEU B 698
ALA B 703
 None
None
PQN  B2002 ( 3.2A)
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 1.19A 5zghB-6fosB:
31.6		 5zghB-6fosB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZGH_B_PQNB843_1
(PSAB)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		6 / 9 ILE B  21
TRP B  22
TRP B 665
ALA B 697
LEU B 698
ALA B 703
 None
None
None
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 0.96A 5zghB-6fosB:
31.6		 5zghB-6fosB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZGH_B_PQNB843_1
(PSAB)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		6 / 9 ILE B  21
TRP B 665
ARG B 666
ALA B 697
LEU B 698
ALA B 703
 None
None
None
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 1.11A 5zghB-6fosB:
31.6		 5zghB-6fosB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZJI_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		8 / 10 MET A 681
PHE A 682
GLY A 686
ARG A 687
TRP A 690
ILE A 694
ALA A 714
LEU A 715
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.3A)
PQN  A2001 ( 3.9A)
None
PQN  A2001 ( 3.2A)
None
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.57A 5zjiA-6fosA:
47.3
5zjiJ-6fosA:
undetectable		 5zjiA-6fosA:
78.87
5zjiJ-6fosA:
19.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZJI_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		7 / 10 MET A 681
SER A 685
GLY A 686
ARG A 687
TRP A 690
ILE A 694
ALA A 714
 PQN  A2001 ( 3.3A)
PQN  A2001 (-4.4A)
PQN  A2001 ( 3.9A)
None
PQN  A2001 ( 3.2A)
None
PQN  A2001 (-3.2A)
 0.80A 5zjiA-6fosA:
47.3
5zjiJ-6fosA:
undetectable		 5zjiA-6fosA:
78.87
5zjiJ-6fosA:
19.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZJI_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		8 / 10 MET B 660
PHE B 661
SER B 664
ARG B 666
TRP B 669
ILE B 673
ALA B 697
LEU B 698
 PQN  B2002 ( 3.2A)
PQN  B2002 ( 4.3A)
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
None
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.82A 5zjiA-6fosB:
28.3
5zjiJ-6fosB:
undetectable		 5zjiA-6fosB:
50.00
5zjiJ-6fosB:
18.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		5 / 10 MET A 681
ARG A 687
TRP A 690
ILE A 694
ALA A 714
 PQN  A2001 ( 3.3A)
None
PQN  A2001 ( 3.2A)
None
PQN  A2001 (-3.2A)
 0.78A 5zjiB-6fosA:
34.2		 5zjiB-6fosA:
34.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		5 / 10 MET A 681
TRP A 690
ILE A 694
ALA A 714
LEU A 715
 PQN  A2001 ( 3.3A)
PQN  A2001 ( 3.2A)
None
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.65A 5zjiB-6fosA:
34.2		 5zjiB-6fosA:
34.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		5 / 10 TRP A  46
ARG A 687
TRP A 690
ILE A 694
ALA A 714
 None
None
PQN  A2001 ( 3.2A)
None
PQN  A2001 (-3.2A)
 0.74A 5zjiB-6fosA:
34.2		 5zjiB-6fosA:
34.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		5 / 10 TRP A  46
TRP A 690
ILE A 694
ALA A 714
LEU A 715
 None
PQN  A2001 ( 3.2A)
None
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.51A 5zjiB-6fosA:
34.2		 5zjiB-6fosA:
34.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		8 / 10 ILE B  25
MET B 660
ARG B 666
TRP B 669
ILE B 673
ALA B 697
LEU B 698
ALA B 703
 CLA  B1201 ( 4.6A)
PQN  B2002 ( 3.2A)
None
PQN  B2002 (-3.3A)
None
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 0.68A 5zjiB-6fosB:
32.7		 5zjiB-6fosB:
83.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		5 / 10 ILE B 125
TRP B  70
ALA B 137
LEU B 133
ALA B  69
 None
 1.43A 5zjiB-6fosB:
32.7		 5zjiB-6fosB:
83.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		9 / 10 TRP B  22
ILE B  25
TRP B 665
ARG B 666
TRP B 669
ILE B 673
ALA B 697
LEU B 698
ALA B 703
 None
CLA  B1201 ( 4.6A)
None
None
PQN  B2002 (-3.3A)
None
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 0.94A 5zjiB-6fosB:
32.7		 5zjiB-6fosB:
83.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW2_A_ACTA511_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		3 / 3 ARG B 201
ILE B 197
SER B 200
 None
 0.85A 5zw2A-6fosB:
undetectable		 5zw2A-6fosB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB303_1
(BIFUNCTIONAL PROTEIN
FOLD)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		4 / 5 TYR A 368
GLN A 383
GLY A 507
ILE A 522
 None
None
None
CLA  A1135 ( 4.9A)
 1.45A 6debB-6fosA:
undetectable		 6debB-6fosA:
21.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HQB_A_PQNA2001_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		7 / 10 TRP A  46
MET A 681
SER A 685
GLY A 686
ARG A 687
TRP A 690
ALA A 714
 None
PQN  A2001 ( 3.3A)
PQN  A2001 (-4.4A)
PQN  A2001 ( 3.9A)
None
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
 1.08A 6hqbA-6fosA:
44.6
6hqbJ-6fosA:
1.6		 6hqbA-6fosA:
68.75
6hqbJ-6fosA:
17.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HQB_A_PQNA2001_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		7 / 10 TRP A  46
MET A 681
SER A 685
GLY A 686
TRP A 690
ALA A 714
LEU A 715
 None
PQN  A2001 ( 3.3A)
PQN  A2001 (-4.4A)
PQN  A2001 ( 3.9A)
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.91A 6hqbA-6fosA:
44.6
6hqbJ-6fosA:
1.6		 6hqbA-6fosA:
68.75
6hqbJ-6fosA:
17.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HQB_A_PQNA2001_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		5 / 10 TRP B  22
GLY B 667
TRP B 669
ALA B 697
LEU B 698
 None
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 1.41A 6hqbA-6fosB:
28.4
6hqbJ-6fosB:
undetectable		 6hqbA-6fosB:
47.92
6hqbJ-6fosB:
14.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HQB_A_PQNA2001_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		7 / 10 TRP B  22
MET B 660
SER B 664
ARG B 666
TRP B 669
ALA B 697
LEU B 698
 None
PQN  B2002 ( 3.2A)
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
 0.84A 6hqbA-6fosB:
28.4
6hqbJ-6fosB:
undetectable		 6hqbA-6fosB:
47.92
6hqbJ-6fosB:
14.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HQB_A_PQNA2001_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX
(Cyanidioschyzon
merolae;
Cyanidioschyzon
merolae) 		8 / 10 TRP A  46
MET A 681
GLY A 686
TRP A 690
ALA A 714
LEU A 715
GLY A 720
LEU J  18
 None
PQN  A2001 ( 3.3A)
PQN  A2001 ( 3.9A)
PQN  A2001 ( 3.2A)
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
None
None
 0.73A 6hqbA-6fosA:
44.6
6hqbJ-6fosA:
1.6		 6hqbA-6fosA:
68.75
6hqbJ-6fosA:
17.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HQB_B_PQNB2002_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		6 / 9 MET A 681
ARG A 687
TRP A 690
ILE A 694
ALA A 714
LEU A 715
 PQN  A2001 ( 3.3A)
None
PQN  A2001 ( 3.2A)
None
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.67A 6hqbB-6fosA:
31.5		 6hqbB-6fosA:
34.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HQB_B_PQNB2002_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		6 / 9 SER A 685
ARG A 687
TRP A 690
ILE A 694
ALA A 714
LEU A 715
 PQN  A2001 (-4.4A)
None
PQN  A2001 ( 3.2A)
None
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.85A 6hqbB-6fosA:
31.5		 6hqbB-6fosA:
34.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HQB_B_PQNB2002_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		8 / 9 MET B 660
SER B 664
ARG B 666
TRP B 669
ILE B 673
ALA B 697
LEU B 698
ALA B 703
 PQN  B2002 ( 3.2A)
CLA  B1023 (-4.5A)
None
PQN  B2002 (-3.3A)
None
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 0.85A 6hqbB-6fosB:
32.7		 6hqbB-6fosB:
85.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HQB_B_PQNB2002_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		8 / 9 SER B 664
TRP B 665
ARG B 666
TRP B 669
ILE B 673
ALA B 697
LEU B 698
ALA B 703
 CLA  B1023 (-4.5A)
None
None
PQN  B2002 (-3.3A)
None
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 1.09A 6hqbB-6fosB:
32.7		 6hqbB-6fosB:
85.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_S_PCFS603_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		4 / 7 GLY B 658
PHE B 711
HIS B 710
VAL B 713
 None
None
CLA  B1239 (-4.1A)
None
 0.98A 6hu9S-6fosB:
undetectable
6hu9q-6fosB:
undetectable		 6hu9S-6fosB:
undetectable
6hu9q-6fosB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		3 / 3 THR A 343
GLU A 323
ASN A 418
 None
 0.85A 6nj9K-6fosA:
undetectable		 6nj9K-6fosA:
undetectable