SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fpc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_A_LPRA801_1
(ANGIOTENSIN
CONVERTING ENZYME)		 6fpc PRO-PRO
ENDOPEPTIDASE
(Paenibacillus
alvei) 		5 / 12 HIS A 137
GLU A 138
HIS A 141
GLU A 181
TYR A 174
 ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.3A)
ZN  A 301 ( 3.4A)
ZN  A 301 ( 2.1A)
ZN  A 301 ( 4.8A)
 0.82A 1j36A-6fpcA:
3.6		 1j36A-6fpcA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_B_LPRB802_1
(ANGIOTENSIN
CONVERTING ENZYME)		 6fpc PRO-PRO
ENDOPEPTIDASE
(Paenibacillus
alvei) 		5 / 12 HIS A 137
GLU A 138
HIS A 141
GLU A 181
TYR A 174
 ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.3A)
ZN  A 301 ( 3.4A)
ZN  A 301 ( 2.1A)
ZN  A 301 ( 4.8A)
 0.82A 1j36B-6fpcA:
3.6		 1j36B-6fpcA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J37_A_X8ZA801_1
(ANGIOTENSIN
CONVERTING ENZYME)		 6fpc PRO-PRO
ENDOPEPTIDASE
(Paenibacillus
alvei) 		5 / 11 HIS A 137
GLU A 138
HIS A 141
GLU A 181
TYR A 174
 ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.3A)
ZN  A 301 ( 3.4A)
ZN  A 301 ( 2.1A)
ZN  A 301 ( 4.8A)
 0.81A 1j37A-6fpcA:
3.8		 1j37A-6fpcA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J37_B_X8ZB802_1
(ANGIOTENSIN
CONVERTING ENZYME)		 6fpc PRO-PRO
ENDOPEPTIDASE
(Paenibacillus
alvei) 		5 / 11 HIS A 137
GLU A 138
HIS A 141
GLU A 181
TYR A 174
 ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.3A)
ZN  A 301 ( 3.4A)
ZN  A 301 ( 2.1A)
ZN  A 301 ( 4.8A)
 0.81A 1j37B-6fpcA:
undetectable		 1j37B-6fpcA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O86_A_LPRA702_1
(ANGIOTENSIN
CONVERTING ENZYME)		 6fpc PRO-PRO
ENDOPEPTIDASE
(Paenibacillus
alvei) 		5 / 12 HIS A 137
GLU A 138
HIS A 141
GLU A 181
TYR A 174
 ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.3A)
ZN  A 301 ( 3.4A)
ZN  A 301 ( 2.1A)
ZN  A 301 ( 4.8A)
 0.74A 1o86A-6fpcA:
3.2		 1o86A-6fpcA:
8.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_A_CRNA401_1
(CREATININE
AMIDOHYDROLASE)		 6fpc PRO-PRO
ENDOPEPTIDASE
(Paenibacillus
alvei) 		4 / 8 GLU A 181
HIS A 137
HIS A 141
GLU A 138
 ZN  A 301 ( 2.1A)
ZN  A 301 ( 3.4A)
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.3A)
 0.91A 1v7zA-6fpcA:
2.3		 1v7zA-6fpcA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_B_CRNB3401_1
(CREATININE
AMIDOHYDROLASE)		 6fpc PRO-PRO
ENDOPEPTIDASE
(Paenibacillus
alvei) 		4 / 8 GLU A 181
HIS A 137
HIS A 141
GLU A 138
 ZN  A 301 ( 2.1A)
ZN  A 301 ( 3.4A)
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.3A)
 0.92A 1v7zB-6fpcA:
2.2		 1v7zB-6fpcA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_C_CRNC4401_1
(CREATININE
AMIDOHYDROLASE)		 6fpc PRO-PRO
ENDOPEPTIDASE
(Paenibacillus
alvei) 		4 / 8 GLU A 181
HIS A 137
HIS A 141
GLU A 138
 ZN  A 301 ( 2.1A)
ZN  A 301 ( 3.4A)
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.3A)
 0.93A 1v7zC-6fpcA:
2.2		 1v7zC-6fpcA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ1_A_HLTA2001_1
(FERRITIN LIGHT CHAIN)		 6fpc PRO-PRO
ENDOPEPTIDASE
(Paenibacillus
alvei) 		4 / 4 LEU A  67
SER A  69
TYR A  68
LEU A  36
 None
 1.22A 1xz1A-6fpcA:
undetectable		 1xz1A-6fpcA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ3_A_ICFA201_1
(FERRITIN LIGHT CHAIN)		 6fpc PRO-PRO
ENDOPEPTIDASE
(Paenibacillus
alvei) 		4 / 4 LEU A  67
SER A  69
TYR A  68
LEU A  36
 None
 1.22A 1xz3A-6fpcA:
undetectable		 1xz3A-6fpcA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_A_LPRA705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 6fpc PRO-PRO
ENDOPEPTIDASE
(Paenibacillus
alvei) 		5 / 12 HIS A 137
GLU A 138
HIS A 141
GLU A 181
TYR A 174
 ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.3A)
ZN  A 301 ( 3.4A)
ZN  A 301 ( 2.1A)
ZN  A 301 ( 4.8A)
 0.75A 2c6nA-6fpcA:
4.1		 2c6nA-6fpcA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 6fpc PRO-PRO
ENDOPEPTIDASE
(Paenibacillus
alvei) 		5 / 12 HIS A 137
GLU A 138
HIS A 141
GLU A 181
TYR A 174
 ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.3A)
ZN  A 301 ( 3.4A)
ZN  A 301 ( 2.1A)
ZN  A 301 ( 4.8A)
 0.84A 2c6nB-6fpcA:
undetectable		 2c6nB-6fpcA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X8Z_A_X8ZA1615_1
(ANGIOTENSIN
CONVERTING ENZYME)		 6fpc PRO-PRO
ENDOPEPTIDASE
(Paenibacillus
alvei) 		5 / 11 HIS A 137
GLU A 138
HIS A 141
GLU A 181
TYR A 174
 ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.3A)
ZN  A 301 ( 3.4A)
ZN  A 301 ( 2.1A)
ZN  A 301 ( 4.8A)
 0.68A 2x8zA-6fpcA:
3.6		 2x8zA-6fpcA:
8.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_1
(ANGIOTENSIN
CONVERTING ENZYME)		 6fpc PRO-PRO
ENDOPEPTIDASE
(Paenibacillus
alvei) 		5 / 12 HIS A 137
GLU A 138
HIS A 141
GLU A 181
TYR A 174
 ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.3A)
ZN  A 301 ( 3.4A)
ZN  A 301 ( 2.1A)
ZN  A 301 ( 4.8A)
 0.70A 2x91A-6fpcA:
3.1		 2x91A-6fpcA:
8.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_A_CRNA303_1
(CREATININE
AMIDOHYDROLASE)		 6fpc PRO-PRO
ENDOPEPTIDASE
(Paenibacillus
alvei) 		4 / 8 GLU A 181
HIS A 137
HIS A 141
GLU A 138
 ZN  A 301 ( 2.1A)
ZN  A 301 ( 3.4A)
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.3A)
 0.93A 3a6jA-6fpcA:
2.2		 3a6jA-6fpcA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_B_CRNB304_1
(CREATININE
AMIDOHYDROLASE)		 6fpc PRO-PRO
ENDOPEPTIDASE
(Paenibacillus
alvei) 		4 / 7 GLU A 181
HIS A 137
HIS A 141
GLU A 138
 ZN  A 301 ( 2.1A)
ZN  A 301 ( 3.4A)
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.3A)
 0.90A 3a6jB-6fpcA:
2.3		 3a6jB-6fpcA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_C_CRNC305_1
(CREATININE
AMIDOHYDROLASE)		 6fpc PRO-PRO
ENDOPEPTIDASE
(Paenibacillus
alvei) 		4 / 8 GLU A 181
HIS A 137
HIS A 141
GLU A 138
 ZN  A 301 ( 2.1A)
ZN  A 301 ( 3.4A)
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.3A)
 0.91A 3a6jC-6fpcA:
2.3		 3a6jC-6fpcA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_E_CRNE306_1
(CREATININE
AMIDOHYDROLASE)		 6fpc PRO-PRO
ENDOPEPTIDASE
(Paenibacillus
alvei) 		4 / 8 GLU A 181
HIS A 137
HIS A 141
GLU A 138
 ZN  A 301 ( 2.1A)
ZN  A 301 ( 3.4A)
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.3A)
 0.94A 3a6jE-6fpcA:
2.1		 3a6jE-6fpcA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_F_CRNF307_1
(CREATININE
AMIDOHYDROLASE)		 6fpc PRO-PRO
ENDOPEPTIDASE
(Paenibacillus
alvei) 		4 / 8 GLU A 181
HIS A 137
HIS A 141
GLU A 138
 ZN  A 301 ( 2.1A)
ZN  A 301 ( 3.4A)
ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.3A)
 0.91A 3a6jF-6fpcA:
2.3		 3a6jF-6fpcA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_1
(MODIFICATION
METHYLASE HHAI)		 6fpc PRO-PRO
ENDOPEPTIDASE
(Paenibacillus
alvei) 		3 / 3 GLU A 181
SER A 112
VAL A 116
 ZN  A 301 ( 2.1A)
None
None
 0.82A 3eeoA-6fpcA:
undetectable		 3eeoA-6fpcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_B_HAEB271_1
(COLLAGENASE 3)		 6fpc PRO-PRO
ENDOPEPTIDASE
(Paenibacillus
alvei) 		3 / 3 HIS A 137
GLU A 138
HIS A 141
 ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.3A)
ZN  A 301 ( 3.4A)
 0.18A 3kecB-6fpcA:
2.6		 3kecB-6fpcA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C2P_A_X8ZA709_1
(ANGIOTENSIN-CONVERTI
NG ENZYME)		 6fpc PRO-PRO
ENDOPEPTIDASE
(Paenibacillus
alvei) 		5 / 11 HIS A 137
GLU A 138
HIS A 141
GLU A 181
TYR A 174
 ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.3A)
ZN  A 301 ( 3.4A)
ZN  A 301 ( 2.1A)
ZN  A 301 ( 4.8A)
 0.79A 4c2pA-6fpcA:
3.7		 4c2pA-6fpcA:
8.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7L_A_SHHA709_1
(LEUKOTRIENE A-4
HYDROLASE)		 6fpc PRO-PRO
ENDOPEPTIDASE
(Paenibacillus
alvei) 		5 / 12 HIS A 137
GLU A 138
HIS A 141
GLU A 181
TYR A 174
 ZN  A 301 ( 3.4A)
ZN  A 301 ( 4.3A)
ZN  A 301 ( 3.4A)
ZN  A 301 ( 2.1A)
ZN  A 301 ( 4.8A)
 0.76A 4r7lA-6fpcA:
4.0		 4r7lA-6fpcA:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_B_HFGB703_0
(AMINOACYL-TRNA
SYNTHETASE)		 6fpc PRO-PRO
ENDOPEPTIDASE
(Paenibacillus
alvei) 		5 / 12 PHE A 183
SER A 152
GLU A 150
VAL A 151
GLY A  71
 None
 1.28A 5f9zB-6fpcA:
undetectable		 5f9zB-6fpcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_1
(CDL2.2)		 6fpc PRO-PRO
ENDOPEPTIDASE
(Paenibacillus
alvei) 		5 / 10 LEU A  36
VAL A 143
ILE A 136
LEU A 140
LEU A  76
 None
 1.19A 5ienB-6fpcA:
undetectable		 5ienB-6fpcA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZP_A_CFFA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 6fpc PRO-PRO
ENDOPEPTIDASE
(Paenibacillus
alvei) 		5 / 9 ILE A 136
VAL A 143
GLU A  57
LEU A  36
ILE A  74
 None
 1.26A 5mzpA-6fpcA:
undetectable		 5mzpA-6fpcA:
11.27