SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fpe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6fpe TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE
(Thermotoga
maritima) 		5 / 10 THR B 138
PHE B 207
ALA B 160
LEU B 271
VAL B 275
 None
 1.26A 1claA-6fpeB:
undetectable		 1claA-6fpeB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRE_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 6fpe ATPASE YJEE,
PREDICTED TO HAVE
ESSENTIAL ROLE IN
CELL WALL
BIOSYNTHESIS
(Thermotoga
maritima) 		5 / 12 ALA E  39
LEU E  33
PHE E  44
ILE E 138
LEU E  21
 APC  E 201 (-4.3A)
None
None
None
None
 1.20A 1dreA-6fpeE:
undetectable		 1dreA-6fpeE:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_E_ACTE3005_0
(BETA-CARBONIC
ANHYDRASE)		 6fpe TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE
(Thermotoga
maritima) 		4 / 7 ASP B 182
GLY B 178
GLY B 177
GLN B 236
 None
PEG  B 402 (-3.4A)
None
None
 0.98A 1ekjE-6fpeB:
undetectable
1ekjF-6fpeB:
undetectable		 1ekjE-6fpeB:
undetectable
1ekjF-6fpeB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 6fpe TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE
(Thermotoga
maritima) 		4 / 6 GLY B  89
THR B  13
THR B   8
ILE B   6
 None
 0.73A 1gtnD-6fpeB:
undetectable
1gtnE-6fpeB:
undetectable		 1gtnD-6fpeB:
undetectable
1gtnE-6fpeB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6fpe TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE
(Thermotoga
maritima) 		5 / 12 THR B 138
PHE B 207
LEU B 271
VAL B 275
PHE B 288
 None
 1.23A 1q23C-6fpeB:
undetectable		 1q23C-6fpeB:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6fpe TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE
(Thermotoga
maritima) 		5 / 11 THR B 138
PHE B 207
LEU B 271
VAL B 275
PHE B 288
 None
 1.26A 1q23L-6fpeB:
undetectable		 1q23L-6fpeB:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_B_BEZB12_0
(CES1 PROTEIN)		 6fpe TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN TSAB
TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE
(Thermotoga
maritima;
Thermotoga
maritima) 		4 / 4 GLY A  79
SER B  99
VAL B  74
LEU B  59
 None
 1.00A 1yajB-6fpeA:
undetectable		 1yajB-6fpeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 6fpe TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE
(Thermotoga
maritima) 		4 / 5 GLY B 161
PRO B 179
VAL B 180
ILE B 181
 PEG  B 402 ( 3.8A)
PEG  B 402 (-3.4A)
None
None
 0.93A 2aoiA-6fpeB:
undetectable		 2aoiA-6fpeB:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2L8M_A_CAMA415_0
(CAMPHOR
5-MONOOXYGENASE)		 6fpe TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN TSAB
(Thermotoga
maritima) 		5 / 9 LEU A  50
VAL A  57
ASP A  56
ILE A  86
VAL A  58
 None
 1.39A 2l8mA-6fpeA:
undetectable		 2l8mA-6fpeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 6fpe TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE
(Thermotoga
maritima) 		5 / 12 SER B   9
ASN B 108
VAL B 107
GLY B 106
ALA B  76
 None
 1.27A 2x2iC-6fpeB:
undetectable		 2x2iC-6fpeB:
6.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_1
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT)		 6fpe TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE
(Thermotoga
maritima) 		5 / 10 VAL B  17
VAL B  15
LEU B  55
GLY B   5
VAL B  74
 None
 1.24A 3ls4H-6fpeB:
undetectable		 3ls4H-6fpeB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_2
(CYTOCHROME P450 3A4)		 6fpe ATPASE YJEE,
PREDICTED TO HAVE
ESSENTIAL ROLE IN
CELL WALL
BIOSYNTHESIS
(Thermotoga
maritima) 		5 / 9 ILE E  76
LEU E  33
PHE E  44
THR E  63
GLY E  40
 None
None
None
None
APC  E 201 (-3.6A)
 1.47A 3nxuB-6fpeE:
undetectable		 3nxuB-6fpeE:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6fpe TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE
(Thermotoga
maritima) 		5 / 10 THR B 138
PHE B 207
LEU B 271
VAL B 275
PHE B 288
 None
 1.23A 3u9fE-6fpeB:
undetectable		 3u9fE-6fpeB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6fpe TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE
(Thermotoga
maritima) 		5 / 10 THR B 138
PHE B 207
LEU B 271
VAL B 275
PHE B 288
 None
 1.22A 3u9fI-6fpeB:
undetectable		 3u9fI-6fpeB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6fpe TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE
(Thermotoga
maritima) 		5 / 10 THR B 138
PHE B 207
LEU B 271
VAL B 275
PHE B 288
 None
 1.34A 3u9fK-6fpeB:
undetectable		 3u9fK-6fpeB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_L_CLML221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6fpe TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE
(Thermotoga
maritima) 		5 / 12 THR B 138
PHE B 207
LEU B 271
VAL B 275
PHE B 288
 None
 1.36A 3u9fJ-6fpeB:
undetectable
3u9fL-6fpeB:
undetectable		 3u9fJ-6fpeB:
undetectable
3u9fL-6fpeB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_N_CLMN221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6fpe TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE
(Thermotoga
maritima) 		5 / 11 THR B 138
PHE B 207
LEU B 271
VAL B 275
PHE B 288
 None
 1.29A 3u9fN-6fpeB:
undetectable
3u9fO-6fpeB:
undetectable		 3u9fN-6fpeB:
undetectable
3u9fO-6fpeB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_P_CLMP221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6fpe TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE
(Thermotoga
maritima) 		5 / 9 THR B 138
PHE B 207
LEU B 271
VAL B 275
PHE B 288
 None
 1.30A 3u9fP-6fpeB:
undetectable		 3u9fP-6fpeB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_S_CLMS221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6fpe TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE
(Thermotoga
maritima) 		5 / 12 THR B 138
PHE B 207
LEU B 271
VAL B 275
PHE B 288
 None
 1.29A 3u9fP-6fpeB:
undetectable
3u9fS-6fpeB:
undetectable		 3u9fP-6fpeB:
undetectable
3u9fS-6fpeB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 6fpe TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE
(Thermotoga
maritima) 		3 / 3 ASN B  27
ASP B 296
ASN B 297
 None
 0.81A 4agaA-6fpeB:
undetectable		 4agaA-6fpeB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_A_CAMA423_0
(CYTOCHROME P450)		 6fpe TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN TSAB
(Thermotoga
maritima) 		5 / 12 ILE A  25
THR A   8
LEU A   4
THR A  76
ILE A  12
 None
 1.03A 4c9oA-6fpeA:
undetectable		 4c9oA-6fpeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_B_CAMB423_0
(CYTOCHROME P450)		 6fpe TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN TSAB
(Thermotoga
maritima) 		5 / 12 ILE A  25
THR A   8
LEU A   4
THR A  76
ILE A  12
 None
 1.03A 4c9oB-6fpeA:
undetectable		 4c9oB-6fpeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KM2_A_TOPA202_1
(DIHYDROFOLATE
REDUCTASE)		 6fpe TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN TSAB
(Thermotoga
maritima) 		5 / 12 ILE A  25
LEU A  80
VAL A  52
LEU A   4
ILE A  14
 None
 1.06A 4km2A-6fpeA:
undetectable		 4km2A-6fpeA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM8_A_RFXA603_1
(TRANSPORTER)		 6fpe TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE
(Thermotoga
maritima) 		5 / 12 VAL B 239
ALA B 238
GLY B 178
PHE B 164
SER B 234
 None
None
PEG  B 402 (-3.4A)
PEG  B 402 ( 4.8A)
None
 1.21A 4mm8A-6fpeB:
undetectable		 4mm8A-6fpeB:
9.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 6fpe TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN TSAB
(Thermotoga
maritima) 		5 / 12 ALA A 110
PRO A  64
GLY A  65
LEU A  91
ASN A  92
 None
 1.02A 4n49A-6fpeA:
undetectable		 4n49A-6fpeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 6fpe TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE
(Thermotoga
maritima) 		5 / 12 VAL B 167
SER B 159
PHE B 209
PHE B 164
GLY B 161
 None
None
None
PEG  B 402 ( 4.8A)
PEG  B 402 ( 3.8A)
 1.42A 4pevB-6fpeB:
undetectable		 4pevB-6fpeB:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 6fpe TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE
(Thermotoga
maritima) 		5 / 12 VAL B 167
SER B 159
PHE B 209
PHE B 164
GLY B 161
 None
None
None
PEG  B 402 ( 4.8A)
PEG  B 402 ( 3.8A)
 1.44A 4pevC-6fpeB:
undetectable		 4pevC-6fpeB:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 6fpe TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE
TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN TSAB
(Thermotoga
maritima) 		4 / 5 GLU B   7
THR B  13
HIS A  33
LEU B  87
 None
 1.24A 5axaA-6fpeB:
undetectable		 5axaA-6fpeB:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 6fpe TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE
TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN TSAB
(Thermotoga
maritima) 		4 / 5 GLU B   7
THR B  13
HIS A  33
LEU B  87
 None
 1.28A 5axaC-6fpeB:
undetectable		 5axaC-6fpeB:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_A_BEZA301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 6fpe TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN TSAB
TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE
(Thermotoga
maritima;
Thermotoga
maritima) 		5 / 10 GLY A  66
GLY A  69
LEU A  67
LEU B  52
ARG A  71
 None
 1.15A 5hwkA-6fpeA:
undetectable		 5hwkA-6fpeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_B_BEZB301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 6fpe TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN TSAB
TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE
(Thermotoga
maritima;
Thermotoga
maritima) 		5 / 10 GLY A  66
GLY A  69
LEU A  67
LEU B  52
ARG A  71
 None
 1.14A 5hwkB-6fpeA:
undetectable		 5hwkB-6fpeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_A_EPAA502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 6fpe TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN TSAB
(Thermotoga
maritima) 		5 / 10 LEU A 156
ILE A 154
PRO A 102
ALA A 103
VAL A 122
 None
 1.38A 5m0oA-6fpeA:
undetectable		 5m0oA-6fpeA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 6fpe TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN TSAB
(Thermotoga
maritima) 		5 / 12 VAL A  57
ASP A  56
ALA A   5
SER A 171
LEU A  22
 None
 1.42A 5m54B-6fpeA:
undetectable		 5m54B-6fpeA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 6fpe ATPASE YJEE,
PREDICTED TO HAVE
ESSENTIAL ROLE IN
CELL WALL
BIOSYNTHESIS
(Thermotoga
maritima) 		5 / 12 ILE E 104
ILE E 126
LEU E  17
VAL E 136
ILE E 138
 None
 1.05A 5mugA-6fpeE:
undetectable		 5mugA-6fpeE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA503_1
(-)		 6fpe TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE
(Thermotoga
maritima) 		5 / 9 LEU B 243
LEU B 271
ILE B 259
LEU B 140
PRO B 289
 None
 1.17A 5og9A-6fpeB:
undetectable		 5og9A-6fpeB:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_1
(REGULATORY PROTEIN
TETR)		 6fpe ATPASE YJEE,
PREDICTED TO HAVE
ESSENTIAL ROLE IN
CELL WALL
BIOSYNTHESIS
(Thermotoga
maritima) 		4 / 7 GLY E 110
TYR E  70
ASP E  80
TYR E  82
 None
None
APC  E 201 ( 4.7A)
None
 1.20A 5vlmG-6fpeE:
undetectable		 5vlmG-6fpeE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6fpe TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE
(Thermotoga
maritima) 		4 / 5 TYR B 284
ARG B 278
THR B 247
LEU B 250
 None
 1.38A 5x19J-6fpeB:
undetectable		 5x19J-6fpeB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6fpe TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE
(Thermotoga
maritima) 		4 / 5 TYR B 284
ARG B 278
THR B 247
LEU B 250
 None
 1.39A 5x1fW-6fpeB:
undetectable		 5x1fW-6fpeB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZNI_A_YMZA302_0
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6fpe TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN TSAB
(Thermotoga
maritima) 		5 / 9 VAL A  40
GLY A  59
VAL A  58
ASP A   7
GLY A  61
 None
 1.34A 5zniA-6fpeA:
undetectable		 5zniA-6fpeA:
22.35