SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fra'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 6fra HUMAN T-CELL
RECEPTOR F11 ALPHA
CHAIN
(Homo
sapiens) 		3 / 3 PRO A 112
LEU A 111
GLN A 143
 None
EDO  A 305 (-4.0A)
None
 0.60A 4pevB-6fraA:
undetectable		 4pevB-6fraA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		 6fra HUMAN T-CELL
RECEPTOR F11 ALPHA
CHAIN
(Homo
sapiens) 		4 / 6 LEU A  44
PHE A  90
ILE A 101
PHE A 102
 EDO  A 304 (-4.9A)
None
None
EDO  A 306 ( 4.1A)
 1.26A 4y4dA-6fraA:
undetectable		 4y4dA-6fraA:
14.85