SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6frv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AGM_A_ACRA495_1
(GLUCOAMYLASE-471)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		12 / 12 ALA A  63
TYR A  72
TRP A  76
ARG A  78
ASP A  79
TRP A 144
GLY A 145
GLU A 204
ARG A 329
TYR A 335
TRP A 341
GLU A 424
 None
 0.19A 1agmA-6frvA:
68.5		 1agmA-6frvA:
83.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AGM_A_ACRA495_2
(GLUCOAMYLASE-471)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		4 / 4 TRP A 202
GLU A 203
LEU A 439
TRP A 441
 None
 0.26A 1agmA-6frvA:
68.5		 1agmA-6frvA:
83.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AGM_A_ACRA496_1
(GLUCOAMYLASE-471)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		12 / 12 ALA A  63
TYR A  72
TRP A  76
ARG A  78
ASP A  79
TRP A 144
GLY A 145
GLU A 204
ARG A 329
TYR A 335
TRP A 341
GLU A 424
 None
 0.19A 1agmA-6frvA:
68.5		 1agmA-6frvA:
83.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AGM_A_ACRA496_2
(GLUCOAMYLASE-471)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		5 / 5 SER A 143
TRP A 202
GLU A 203
LEU A 439
TRP A 441
 None
 0.27A 1agmA-6frvA:
68.5		 1agmA-6frvA:
83.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GAH_A_ACRA497_1
(GLUCOAMYLASE-471)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		12 / 12 TYR A  72
TRP A  76
ARG A  78
ASP A  79
TRP A 144
GLY A 145
TYR A 199
GLU A 203
GLU A 204
TYR A 335
TRP A 341
GLU A 424
 None
 0.25A 1gahA-6frvA:
68.4		 1gahA-6frvA:
83.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		6 / 6 ALA A  63
SER A 143
TRP A 202
ARG A 329
LEU A 439
TRP A 441
 None
 0.53A 1gahA-6frvA:
68.4		 1gahA-6frvA:
83.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_A_ACRA700_1
(GLUCOAMYLASE)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		9 / 12 ALA A  63
TYR A  72
TRP A  76
ARG A  78
ASP A  79
GLU A 204
ARG A 329
TYR A 335
TRP A 441
 None
 0.38A 1lf9A-6frvA:
5.4		 1lf9A-6frvA:
9.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_A_ACRA700_1
(GLUCOAMYLASE)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		5 / 12 ALA A  63
TYR A  72
TRP A 144
GLU A 204
TYR A 335
 None
 0.99A 1lf9A-6frvA:
5.4		 1lf9A-6frvA:
9.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_A_ACRA700_2
(GLUCOAMYLASE)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		4 / 4 TRP A 202
GLU A 203
TRP A 341
LEU A 439
 None
 0.40A 1lf9A-6frvA:
5.4		 1lf9A-6frvA:
9.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_B_ACRB701_1
(GLUCOAMYLASE)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		9 / 12 ALA A  63
TYR A  72
TRP A  76
ARG A  78
ASP A  79
GLU A 204
ARG A 329
TYR A 335
TRP A 341
 None
 0.46A 1lf9B-6frvA:
5.4		 1lf9B-6frvA:
9.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_B_ACRB701_1
(GLUCOAMYLASE)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		5 / 12 ALA A  63
TYR A  72
TRP A 144
GLU A 204
TYR A 335
 None
 0.98A 1lf9B-6frvA:
5.4		 1lf9B-6frvA:
9.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_B_ACRB701_1
(GLUCOAMYLASE)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		5 / 12 ASP A  79
GLN A 148
GLU A 204
TYR A 335
TRP A 341
 None
 1.34A 1lf9B-6frvA:
5.4		 1lf9B-6frvA:
9.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_B_ACRB701_2
(GLUCOAMYLASE)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		4 / 4 TRP A 202
GLU A 203
LEU A 439
TRP A 441
 None
 0.43A 1lf9B-6frvA:
5.4		 1lf9B-6frvA:
9.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_1
(ADENOSINE KINASE)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		5 / 12 ILE A  46
LEU A  98
GLY A  47
THR A 101
LEU A  87
 None
 1.05A 1liiA-6frvA:
undetectable		 1liiA-6frvA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ME7_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		4 / 8 ASP A 238
SER A 235
GLY A 231
GLY A 223
 None
 0.75A 1me7A-6frvA:
undetectable		 1me7A-6frvA:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA8_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		5 / 12 ALA A  56
THR A 440
ILE A  42
ARG A  39
LEU A  87
 None
 0.98A 1ra8A-6frvA:
undetectable		 1ra8A-6frvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_B_SAMB500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		4 / 8 PHE A 211
ASN A 271
TRP A 202
ALA A 259
 None
 1.17A 1rqpC-6frvA:
undetectable		 1rqpC-6frvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_C_SAMC500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		4 / 8 PHE A 211
ASN A 271
TRP A 202
ALA A 259
 None
 1.14A 1rqpA-6frvA:
undetectable		 1rqpA-6frvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		4 / 6 GLY A 163
ILE A 160
GLN A 164
VAL A  88
 None
 0.95A 1rs7B-6frvA:
undetectable		 1rs7B-6frvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ULV_A_ACRA3000_1
(GLUCODEXTRANASE)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		9 / 12 ALA A  63
TYR A  72
TRP A  76
ARG A  78
ASP A  79
GLU A 204
ARG A 329
TYR A 335
TRP A 341
 None
 0.51A 1ulvA-6frvA:
31.5		 1ulvA-6frvA:
6.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ULV_A_ACRA3000_2
(GLUCODEXTRANASE)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		4 / 5 GLN A 148
GLU A 203
LEU A 343
TRP A 341
 None
 1.45A 1ulvA-6frvA:
31.4		 1ulvA-6frvA:
6.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ULV_A_ACRA3000_2
(GLUCODEXTRANASE)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		4 / 5 TRP A 202
GLU A 203
LEU A 439
TRP A 441
 None
 0.28A 1ulvA-6frvA:
31.4		 1ulvA-6frvA:
6.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_ACTB294_0
(GLYCINE
N-METHYLTRANSFERASE)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		4 / 6 ALA A  63
TYR A 443
ILE A  42
LEU A 439
 None
 1.04A 1xvaA-6frvA:
undetectable
1xvaB-6frvA:
undetectable		 1xvaA-6frvA:
undetectable
1xvaB-6frvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA995_1
(GLUCOAMYLASE GLU1)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		12 / 12 ALA A  63
TYR A  72
TRP A  76
ARG A  78
ASP A  79
TRP A 144
GLY A 145
GLU A 204
ARG A 329
TYR A 335
TRP A 341
GLU A 424
 None
 0.24A 2f6dA-6frvA:
46.0		 2f6dA-6frvA:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA995_2
(GLUCOAMYLASE GLU1)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		4 / 4 TRP A 202
GLU A 203
LEU A 439
TRP A 441
 None
 0.27A 2f6dA-6frvA:
46.0		 2f6dA-6frvA:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_0
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		5 / 12 ILE A 244
ALA A 214
THR A 157
VAL A 183
GLN A 164
 None
 1.31A 2rctA-6frvA:
undetectable		 2rctA-6frvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_A_SAMA1299_0
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		4 / 8 PHE A 211
ASN A 271
TRP A 202
ALA A 259
 None
 1.15A 2v7uA-6frvA:
undetectable		 2v7uA-6frvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		5 / 9 PHE A 211
SER A 209
ALA A 270
LEU A 274
GLY A 275
 None
 1.39A 2wsfA-6frvA:
undetectable		 2wsfA-6frvA:
8.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_X_CPFX1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		4 / 4 ARG A 146
GLY A 129
GLU A 130
SER A 209
 None
 1.28A 2xctS-6frvA:
undetectable
2xctU-6frvA:
undetectable		 2xctS-6frvA:
9.47
2xctU-6frvA:
9.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_A_CE3A303_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		4 / 4 ASN A 339
SER A 423
SER A  64
ARG A 437
 None
 1.37A 3hlwA-6frvA:
undetectable		 3hlwA-6frvA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B304_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		4 / 5 ASN A 339
SER A 423
SER A  64
ARG A 437
 None
 1.39A 3hlwB-6frvA:
undetectable		 3hlwB-6frvA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2U_A_ELVA397_1
(INTEGRASE)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		4 / 5 ASP A 430
ASP A 427
TYR A 336
GLU A 432
 None
 1.47A 3l2uA-6frvA:
undetectable		 3l2uA-6frvA:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		5 / 11 THR A 176
GLN A 164
GLY A 231
THR A 228
ALA A 227
 None
 1.31A 3mg0H-6frvA:
undetectable
3mg0I-6frvA:
undetectable		 3mg0H-6frvA:
15.98
3mg0I-6frvA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		5 / 11 GLU A 424
GLY A 328
PHE A 342
ALA A 326
ASP A 333
 None
 1.23A 3nmuB-6frvA:
undetectable
3nmuJ-6frvA:
undetectable		 3nmuB-6frvA:
undetectable
3nmuJ-6frvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		4 / 6 GLY A 163
ILE A 160
GLN A 164
VAL A  88
 None
 0.89A 4d39B-6frvA:
undetectable		 4d39B-6frvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DFR_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		5 / 12 ALA A  56
THR A 440
ILE A  42
ARG A  39
LEU A  87
 None
 0.95A 4dfrA-6frvA:
undetectable		 4dfrA-6frvA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		4 / 8 ASP A 333
ASP A 200
GLU A 424
ASP A 269
 None
 1.00A 4feuD-6frvA:
undetectable		 4feuD-6frvA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		4 / 7 ASP A 333
ASP A 200
GLU A 424
ASP A 269
 None
 1.05A 4fevB-6frvA:
undetectable		 4fevB-6frvA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		4 / 7 ASP A 333
ASP A 200
GLU A 424
ASP A 269
 None
 1.05A 4fewB-6frvA:
undetectable		 4fewB-6frvA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		4 / 8 ASP A 333
ASP A 200
GLU A 424
ASP A 269
 None
 1.05A 4gkhD-6frvA:
undetectable		 4gkhD-6frvA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		4 / 7 ILE A 244
LEU A 248
PHE A 210
GLY A 275
 None
 0.90A 4hbfA-6frvA:
undetectable		 4hbfA-6frvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK6_A_LURA201_1
(TRANSTHYRETIN)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		4 / 4 LYS A 402
LEU A 356
ALA A 405
VAL A 409
 None
 0.93A 4ik6A-6frvA:
undetectable		 4ik6A-6frvA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_ACTA803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		4 / 6 GLY A 163
ILE A 160
GLN A 164
VAL A  88
 None
 0.98A 4kcnA-6frvA:
undetectable		 4kcnA-6frvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		5 / 12 GLY A  50
VAL A 135
THR A 440
ILE A  42
VAL A  83
 None
 1.31A 4okwA-6frvA:
undetectable		 4okwA-6frvA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA306_1
(CHITOSANASE)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		3 / 3 SER A  64
ASP A 438
GLN A 433
 None
NAG  A 703 (-3.1A)
None
 0.87A 4oltA-6frvA:
undetectable
4oltB-6frvA:
undetectable		 4oltA-6frvA:
17.67
4oltB-6frvA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLE_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		5 / 12 ALA A  56
THR A 440
ILE A  42
ARG A  39
LEU A  87
 None
 1.02A 4qleA-6frvA:
undetectable		 4qleA-6frvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB304_1
(CHITOSANASE)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		3 / 3 GLN A 433
SER A  64
ASP A 438
 None
None
NAG  A 703 (-3.1A)
 0.88A 4qwpA-6frvA:
undetectable
4qwpB-6frvA:
undetectable		 4qwpA-6frvA:
17.34
4qwpB-6frvA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		5 / 12 ALA A 466
SER A 465
GLY A 462
ALA A 227
GLY A 223
 None
 1.27A 4r29A-6frvA:
undetectable		 4r29A-6frvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5F_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		5 / 12 ALA A  56
THR A 440
ILE A  42
ARG A  39
LEU A  87
 None
 1.03A 4x5fA-6frvA:
undetectable		 4x5fA-6frvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5F_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		5 / 12 ALA A  56
THR A 440
ILE A  42
ARG A  39
LEU A  87
 None
 1.03A 4x5fB-6frvA:
undetectable		 4x5fB-6frvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5G_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		5 / 12 ALA A  56
THR A 440
ILE A  42
ARG A  39
LEU A  87
 None
 1.02A 4x5gA-6frvA:
undetectable		 4x5gA-6frvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		5 / 10 ASP A 307
HIS A 302
VAL A 306
VAL A 327
ALA A 405
 None
 1.02A 4yhaB-6frvA:
undetectable		 4yhaB-6frvA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A6I_A_TCWA1124_1
(TRANSTHYRETIN)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		4 / 6 LYS A 402
LEU A 356
ALA A 405
VAL A 409
 None
 1.10A 5a6iA-6frvA:
undetectable		 5a6iA-6frvA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		4 / 5 SER A 209
ARG A 146
GLY A 129
GLU A 130
 None
 1.06A 5btiA-6frvA:
undetectable
5btiB-6frvA:
undetectable		 5btiA-6frvA:
10.46
5btiB-6frvA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_1
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		3 / 3 ASP A 287
GLU A 366
SER A 460
 None
 0.78A 5bw4B-6frvA:
undetectable		 5bw4B-6frvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		5 / 11 THR A 176
GLN A 164
GLY A 231
THR A 228
ALA A 227
 None
 1.21A 5bxnH-6frvA:
undetectable
5bxnI-6frvA:
undetectable		 5bxnH-6frvA:
15.98
5bxnI-6frvA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		5 / 11 THR A 176
GLN A 164
GLY A 231
THR A 228
ALA A 227
 None
 1.19A 5bxnV-6frvA:
undetectable
5bxnW-6frvA:
undetectable		 5bxnV-6frvA:
15.98
5bxnW-6frvA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C6P_A_4YHA601_1
(PROTEIN C)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		4 / 6 ALA A 191
SER A 188
SER A 233
ASP A 238
 None
 1.20A 5c6pA-6frvA:
undetectable		 5c6pA-6frvA:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_E_MFXE2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		4 / 5 SER A 209
ARG A 146
GLY A 129
GLU A 130
 None
 0.97A 5cdqA-6frvA:
undetectable
5cdqB-6frvA:
undetectable
5cdqC-6frvA:
undetectable		 5cdqA-6frvA:
12.36
5cdqB-6frvA:
23.53
5cdqC-6frvA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_V_MFXV2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		4 / 5 SER A 209
ARG A 146
GLY A 129
GLU A 130
 None
 0.97A 5cdqR-6frvA:
undetectable
5cdqS-6frvA:
undetectable
5cdqT-6frvA:
undetectable		 5cdqR-6frvA:
12.36
5cdqS-6frvA:
23.53
5cdqT-6frvA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_LCRA612_1
(SERUM ALBUMIN)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		5 / 9 LEU A 201
LEU A 273
LEU A 274
LEU A 343
ALA A 347
 None
 0.99A 5dqfA-6frvA:
undetectable		 5dqfA-6frvA:
10.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		5 / 12 VAL A 183
ASP A 186
THR A 101
GLY A  81
LEU A  84
 None
 0.96A 5m50B-6frvA:
undetectable		 5m50B-6frvA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		5 / 12 VAL A 183
ASP A 186
THR A 101
GLY A  81
LEU A  84
 None
 0.96A 5m50E-6frvA:
undetectable		 5m50E-6frvA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		5 / 12 VAL A 183
ASP A 186
THR A 101
GLY A  81
LEU A  84
 None
 1.02A 5m5cB-6frvA:
undetectable		 5m5cB-6frvA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		5 / 10 VAL A 183
ASP A 186
THR A 101
GLY A  81
LEU A  84
 None
 1.01A 5m5cE-6frvA:
undetectable		 5m5cE-6frvA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UJX_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		5 / 12 ALA A  56
THR A 440
ILE A  42
ARG A  39
LEU A  87
 None
 0.98A 5ujxA-6frvA:
undetectable		 5ujxA-6frvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_1
(REGULATORY PROTEIN
TETR)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		4 / 7 GLY A  81
TRP A 441
ASP A 150
ASP A 186
 None
 1.06A 5vlmE-6frvA:
0.6		 5vlmE-6frvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		4 / 6 LEU A 446
ASP A 354
GLN A 292
GLU A 350
 None
 1.48A 6djzC-6frvA:
undetectable		 6djzC-6frvA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6FHW_A_ACRA801_1
(GLUCOAMYLASE P)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		12 / 12 ALA A  63
TYR A  72
TRP A  76
ARG A  78
ASP A  79
TRP A 144
GLY A 145
GLU A 204
ARG A 329
TYR A 335
TRP A 341
TRP A 441
 None
 0.33A 6fhwA-6frvA:
60.8		 6fhwA-6frvA:
41.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6FHW_A_ACRA801_2
(GLUCOAMYLASE P)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		3 / 3 TRP A 202
GLU A 203
GLU A 424
 None
 0.25A 6fhwA-6frvA:
60.8		 6fhwA-6frvA:
41.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6FHW_A_ACRA801_2
(GLUCOAMYLASE P)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		3 / 3 TRP A 441
GLU A 424
GLU A 203
 None
 0.84A 6fhwA-6frvA:
60.8		 6fhwA-6frvA:
41.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6FHW_B_ACRB801_1
(GLUCOAMYLASE P)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		12 / 12 ALA A  63
TYR A  72
TRP A  76
ARG A  78
ASP A  79
TRP A 144
GLY A 145
GLU A 204
ARG A 329
TYR A 335
TRP A 341
TRP A 441
 None
 0.34A 6fhwB-6frvA:
61.1		 6fhwB-6frvA:
41.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6FHW_B_ACRB801_2
(GLUCOAMYLASE P)		 6frv GLUCOAMYLASE
(Aspergillus
niger) 		4 / 4 TRP A 202
GLU A 203
GLU A 424
LEU A 439
 None
 0.27A 6fhwB-6frvA:
61.1		 6fhwB-6frvA:
41.25