SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fsf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRQ_A_STRA501_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 6fsf GTPASE-ACTIVATING
PROTEIN BEM3
(Saccharomyces
cerevisiae) 		5 / 11 LEU A 596
VAL A 556
ILE A 553
GLU A 724
LEU A 580
 None
 1.02A 1mrqA-6fsfA:
undetectable		 1mrqA-6fsfA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 6fsf GTPASE-ACTIVATING
PROTEIN BEM3
(Saccharomyces
cerevisiae) 		4 / 7 ILE A 661
GLN A 668
GLY A 660
ARG A 658
 None
 0.92A 3bjwF-6fsfA:
undetectable		 3bjwF-6fsfA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I71_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 6fsf GTPASE-ACTIVATING
PROTEIN BEM3
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 537
ALA A 536
PHE A 512
GLY A 513
VAL A 507
 None
 0.79A 5i71A-6fsfA:
undetectable		 5i71A-6fsfA:
9.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA511_1
(PROTON-GATED ION
CHANNEL)		 6fsf GTPASE-ACTIVATING
PROTEIN BEM3
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 517
ALA A 536
ILE A 537
GLU A 545
 None
 0.75A 5mvmA-6fsfA:
undetectable
5mvmB-6fsfA:
undetectable		 5mvmA-6fsfA:
21.84
5mvmB-6fsfA:
21.84