SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fsw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1321_0
(CHLOROPEROXIDASE)		 6fsw RIBOSOME MATURATION
PROTEIN SDO1-LIKE
PROTEIN
(Archaeoglobus
fulgidus) 		4 / 5 LEU A  45
PHE A  51
VAL A  74
ALA A  78
 None
 1.20A 2cizA-6fswA:
undetectable		 2cizA-6fswA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNP_A_ROCA401_2
(PROTEASE)		 6fsw RIBOSOME MATURATION
PROTEIN SDO1-LIKE
PROTEIN
(Archaeoglobus
fulgidus) 		5 / 11 LEU A  45
VAL A  10
ILE A  89
VAL A  23
VAL A  25
 None
 0.93A 2nnpB-6fswA:
undetectable		 2nnpB-6fswA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA502_0
(FERROCHELATASE)		 6fsw RIBOSOME MATURATION
PROTEIN SDO1-LIKE
PROTEIN
(Archaeoglobus
fulgidus) 		4 / 8 PRO A 121
SER A 110
GLY A 213
MET A 211
 None
 0.99A 2qd3A-6fswA:
undetectable		 2qd3A-6fswA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6fsw RIBOSOME MATURATION
PROTEIN SDO1-LIKE
PROTEIN
(Archaeoglobus
fulgidus) 		4 / 7 PRO A 121
SER A 110
GLY A 213
MET A 211
 None
 1.04A 3hcrB-6fswA:
undetectable		 3hcrB-6fswA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 6fsw RIBOSOME MATURATION
PROTEIN SDO1-LIKE
PROTEIN
(Archaeoglobus
fulgidus) 		3 / 3 ASP A  73
PHE A  41
ARG A  79
 None
 1.02A 5yw0A-6fswA:
undetectable		 5yw0A-6fswA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_B_TRPB403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)		 6fsw RIBOSOME MATURATION
PROTEIN SDO1-LIKE
PROTEIN
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 129
GLU A 128
ARG A 126
PRO A 124
 None
 1.08A 6a4iB-6fswA:
undetectable		 6a4iB-6fswA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 6fsw RIBOSOME MATURATION
PROTEIN SDO1-LIKE
PROTEIN
(Archaeoglobus
fulgidus) 		4 / 7 ALA A  30
TYR A  28
GLN A  88
VAL A  87
 None
 0.93A 6cduA-6fswA:
undetectable
6cduE-6fswA:
undetectable		 6cduA-6fswA:
undetectable
6cduE-6fswA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_H_EY4H500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 6fsw RIBOSOME MATURATION
PROTEIN SDO1-LIKE
PROTEIN
(Archaeoglobus
fulgidus) 		4 / 7 GLN A  88
VAL A  87
ALA A  30
TYR A  28
 None
 0.94A 6cduH-6fswA:
1.2
6cduI-6fswA:
undetectable		 6cduH-6fswA:
undetectable
6cduI-6fswA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_0
(PROTEASE)		 6fsw RIBOSOME MATURATION
PROTEIN SDO1-LIKE
PROTEIN
(Archaeoglobus
fulgidus) 		6 / 12 LEU A  45
ALA A  30
VAL A  10
ILE A  89
VAL A  23
VAL A  25
 None
 1.31A 6dh0A-6fswA:
undetectable		 6dh0A-6fswA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_D_GLYD713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 6fsw RIBOSOME MATURATION
PROTEIN SDO1-LIKE
PROTEIN
(Archaeoglobus
fulgidus) 		3 / 3 ARG A 126
HIS A 122
ARG A 117
 None
 1.17A 6dwdD-6fswA:
undetectable		 6dwdD-6fswA:
undetectable