SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6ft1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))
6ft1 FLAVODOXIN
(Bacillus
cereus)
4 / 7 ASN A  14
THR A  59
ASP A  93
TYR A  96
FMN  A1001 (-3.6A)
FMN  A1001 (-3.8A)
FMN  A1001 (-4.8A)
FMN  A1001 (-3.5A)
0.42A 1bu5A-6ft1A:
24.2
1bu5A-6ft1A:
29.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))
6ft1 FLAVODOXIN
(Bacillus
cereus)
4 / 8 ASN A  14
THR A  59
ASP A  93
TYR A  96
FMN  A1001 (-3.6A)
FMN  A1001 (-3.8A)
FMN  A1001 (-4.8A)
FMN  A1001 (-3.5A)
0.40A 1bu5B-6ft1A:
24.1
1bu5B-6ft1A:
29.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D0V_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
4 / 8 GLY A  13
GLY A  56
PHE A   8
GLY A  90
FMN  A1001 (-4.0A)
None
None
None
0.76A 1d0vA-6ft1A:
undetectable
1d0vA-6ft1A:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHI_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.85A 1dhiA-6ft1A:
undetectable
1dhiA-6ft1A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHI_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 11 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.87A 1dhiB-6ft1A:
2.7
1dhiB-6ft1A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHJ_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.88A 1dhjA-6ft1A:
2.9
1dhjA-6ft1A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHJ_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.87A 1dhjB-6ft1A:
2.7
1dhjB-6ft1A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRA_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.85A 1draA-6ft1A:
2.8
1draA-6ft1A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRA_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.87A 1draB-6ft1A:
2.7
1draB-6ft1A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRB_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.84A 1drbA-6ft1A:
2.7
1drbA-6ft1A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRB_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.87A 1drbB-6ft1A:
2.7
1drbB-6ft1A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.91A 1ra2A-6ft1A:
undetectable
1ra2A-6ft1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.88A 1ra3A-6ft1A:
2.7
1ra3A-6ft1A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA8_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.91A 1ra8A-6ft1A:
undetectable
1ra8A-6ft1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.91A 1rb2A-6ft1A:
undetectable
1rb2A-6ft1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB3_B_MTXB161_1
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.95A 1rb3B-6ft1A:
2.8
1rb3B-6ft1A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RD7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.89A 1rd7A-6ft1A:
2.5
1rd7A-6ft1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RD7_B_FOLB361_0
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
1.03A 1rd7B-6ft1A:
2.5
1rd7B-6ft1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.96A 1rx2A-6ft1A:
undetectable
1rx2A-6ft1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.91A 1rx7A-6ft1A:
2.7
1rx7A-6ft1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_B_SAMB500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 11 VAL A   5
ALA A  87
ILE A 107
ALA A 115
PHE A 139
None
1.29A 2admB-6ft1A:
undetectable
2admB-6ft1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D0K_B_FOLB2161_0
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
6 / 12 ILE A  38
ALA A  57
PHE A  72
ILE A  53
LEU A  47
ILE A   7
None
1.24A 2d0kB-6ft1A:
2.7
2d0kB-6ft1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRC_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.88A 2drcA-6ft1A:
undetectable
2drcA-6ft1A:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRC_B_MTXB161_1
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.88A 2drcB-6ft1A:
2.7
2drcB-6ft1A:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO6_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 LEU A  81
ILE A  79
LEU A  47
ALA A  86
VAL A 117
None
1.18A 2qo6A-6ft1A:
undetectable
2qo6A-6ft1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DRC_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.87A 3drcA-6ft1A:
undetectable
3drcA-6ft1A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DRC_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.88A 3drcB-6ft1A:
2.7
3drcB-6ft1A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FZG_A_SAMA300_0
(16S RRNA METHYLASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 PHE A 143
GLY A  56
ILE A  53
LEU A 122
VAL A 117
None
1.06A 3fzgA-6ft1A:
undetectable
3fzgA-6ft1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQ9_A_MTXA2001_1
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.88A 3tq9A-6ft1A:
undetectable
3tq9A-6ft1A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 PRO A  42
PHE A  72
LEU A 110
VAL A  88
ALA A   9
None
1.42A 4a84A-6ft1A:
undetectable
4a84A-6ft1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ASD_A_BAXA1500_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)
6ft1 FLAVODOXIN
(Bacillus
cereus)
4 / 6 ILE A  33
VAL A  25
LEU A 137
ILE A  22
None
0.92A 4asdA-6ft1A:
undetectable
4asdA-6ft1A:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DFR_B_MTXB162_1
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.87A 4dfrB-6ft1A:
2.6
4dfrB-6ft1A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJ1_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.94A 4ej1A-6ft1A:
undetectable
4ej1A-6ft1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FHB_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.98A 4fhbA-6ft1A:
undetectable
4fhbA-6ft1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I13_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.94A 4i13A-6ft1A:
undetectable
4i13A-6ft1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.88A 4kjjA-6ft1A:
undetectable
4kjjA-6ft1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJK_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.95A 4kjkA-6ft1A:
2.8
4kjkA-6ft1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJL_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.93A 4kjlA-6ft1A:
undetectable
4kjlA-6ft1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3Q_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.89A 4p3qA-6ft1A:
undetectable
4p3qA-6ft1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3R_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.89A 4p3rA-6ft1A:
undetectable
4p3rA-6ft1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTH_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.91A 4pthA-6ft1A:
2.2
4pthA-6ft1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5G_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.90A 4x5gB-6ft1A:
2.4
4x5gB-6ft1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.94A 4x5iA-6ft1A:
2.9
4x5iA-6ft1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.90A 5eajA-6ft1A:
undetectable
5eajA-6ft1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M24_A_9CRA501_1
(RETINOIC ACID
RECEPTOR GAMMA)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ALA A  44
ILE A  36
GLY A  52
LEU A 110
ILE A  79
None
1.11A 5m24A-6ft1A:
undetectable
5m24A-6ft1A:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UJX_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.91A 5ujxA-6ft1A:
undetectable
5ujxA-6ft1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6J_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.89A 5z6jA-6ft1A:
undetectable
5z6jA-6ft1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6K_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
0.91A 5z6kA-6ft1A:
undetectable
5z6kA-6ft1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)
6ft1 FLAVODOXIN
(Bacillus
cereus)
5 / 12 ILE A  38
ALA A  57
ILE A  53
LEU A  47
ILE A   7
None
1.04A 7dfrA-6ft1A:
undetectable
7dfrA-6ft1A:
undetectable