SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6ftx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		 6ftx -
(-) 		4 / 7 TYR W 211
ASP W 253
GLU W 252
PHE W 213
 None
 1.43A 1b2iA-6ftxW:
undetectable		 1b2iA-6ftxW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_2
(TRANSTHYRETIN)		 6ftx -
(-) 		4 / 8 MET W 815
LEU W 819
THR W 785
VAL W 714
 None
 0.62A 1sn5C-6ftxW:
undetectable		 1sn5C-6ftxW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 6ftx -
(-) 		5 / 12 TYR W1052
LEU W1017
LEU W1127
MET W1055
LEU W1139
 None
 1.46A 1zgyA-6ftxW:
undetectable		 1zgyA-6ftxW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O5Y_H_STRH249_1
(CHIMERIC ANTIBODY
FAB 1E9-DB3)		 6ftx -
(-) 		4 / 7 ASN W 315
GLY W 458
MET W 457
SER W 747
 None
 1.02A 2o5yH-6ftxW:
undetectable
2o5yL-6ftxW:
undetectable		 2o5yH-6ftxW:
undetectable
2o5yL-6ftxW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 6ftx -
(-) 		4 / 7 PHE W 361
ALA W 421
LEU W 418
ALA W 388
 None
 1.16A 2vcvA-6ftxW:
undetectable		 2vcvA-6ftxW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZI9_A_CL9A401_2
(DEOXYCYTIDINE KINASE)		 6ftx -
(-) 		3 / 3 ASP W 764
PHE W 767
LEU W 715
 None
 0.64A 2zi9A-6ftxW:
undetectable		 2zi9A-6ftxW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_2
(PHOSPHOLIPASE A2)		 6ftx -
(-) 		4 / 5 VAL W 412
VAL W 409
PHE W 370
ARG W 597
 None
 1.28A 3bjwB-6ftxW:
undetectable		 3bjwB-6ftxW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_D_SAMD301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 6ftx -
(-) 		5 / 12 GLY W 774
ILE W 778
ASP W 742
ARG W 740
LEU W 741
 None
 1.05A 3iv6D-6ftxW:
2.7		 3iv6D-6ftxW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_2
(HIV-1 PROTEASE)		 6ftx -
(-) 		5 / 12 ALA W 448
ILE W 371
GLY W 373
THR W 408
VAL W 412
 None
 0.84A 3so9B-6ftxW:
undetectable		 3so9B-6ftxW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6ftx -
(-) 		4 / 4 PRO W 607
LEU W 606
ILE W 808
ARG W 807
 None
None
None
ADP  W1302 (-2.8A)
 1.27A 3w1wA-6ftxW:
2.6		 3w1wA-6ftxW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1479_0
(MJ0495-LIKE PROTEIN)		 6ftx -
(-) 		4 / 5 THR W 631
ILE W 629
GLU W 624
PHE W 646
 None
 1.44A 4ac9C-6ftxW:
undetectable		 4ac9C-6ftxW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 6ftx -
(-) 		4 / 5 THR W 631
ILE W 629
GLU W 624
PHE W 646
 None
 1.44A 4acaC-6ftxW:
undetectable		 4acaC-6ftxW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HXY_B_ACAB502_1
(PLM1)		 6ftx -
(-) 		4 / 7 VAL W 335
SER W 293
GLN W 339
ASP W1200
 None
 0.91A 4hxyB-6ftxW:
undetectable		 4hxyB-6ftxW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_1
(METHYLTRANSFERASE
MPPJ)		 6ftx -
(-) 		3 / 3 ARG W 804
ASP W 798
ASP W 790
 BEF  W1301 (-3.6A)
None
None
 0.80A 4kicB-6ftxW:
undetectable		 4kicB-6ftxW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3U_B_SVRB101_1
(CHROMOBOX PROTEIN
HOMOLOG 7)		 6ftx -
(-) 		5 / 9 LEU W 214
TRP W 217
THR W 226
TRP W 227
LEU W 239
 None
 0.76A 4x3uA-6ftxW:
4.7		 4x3uA-6ftxW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3U_B_SVRB101_2
(CHROMOBOX PROTEIN
HOMOLOG 7)		 6ftx -
(-) 		5 / 10 LEU W 214
TRP W 217
THR W 226
TRP W 227
LEU W 239
 None
 0.71A 4x3uB-6ftxW:
7.9		 4x3uB-6ftxW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_A_1FLA1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 6ftx -
(-) 		4 / 8 PRO W1201
ILE W 327
PRO W 287
LEU W 330
 None
 0.89A 5g48A-6ftxW:
undetectable		 5g48A-6ftxW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		 6ftx -
(-) 		4 / 8 ASP W 450
PRO W 449
PHE W 370
SER W 416
 None
 1.00A 5l1fA-6ftxW:
undetectable
5l1fB-6ftxW:
undetectable		 5l1fA-6ftxW:
undetectable
5l1fB-6ftxW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_A_ACTA701_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 6ftx -
(-) 		3 / 3 LYS W 696
LYS W 822
SER W 821
 None
 1.19A 5odiA-6ftxW:
undetectable		 5odiA-6ftxW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 6ftx -
(-) 		5 / 12 HIS W 185
TYR W 245
LEU W 242
ILE W 233
LEU W 278
 None
 1.24A 5ycpA-6ftxW:
undetectable		 5ycpA-6ftxW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YN6_A_SAMA401_0
(NSP16 PROTEIN)		 6ftx -
(-) 		5 / 12 GLY W 178
ASN W 225
LEU W 223
ASP W 180
PHE W 284
 None
 1.29A 5yn6A-6ftxW:
undetectable		 5yn6A-6ftxW:
undetectable