SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fu4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)		 6fu4 PROBABLE CHEMOTAXIS
TRANSDUCER
(Pseudomonas
aeruginosa) 		5 / 12 ALA A 101
ASP A 100
LEU A  99
GLY A 148
LEU A 147
 None
 1.08A 2jfaB-6fu4A:
undetectable		 2jfaB-6fu4A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_A_TOPA200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 6fu4 PROBABLE CHEMOTAXIS
TRANSDUCER
(Pseudomonas
aeruginosa) 		5 / 10 ALA A 327
ALA A  66
ILE A  69
LEU A 245
PHE A  73
 None
 1.21A 3fl9A-6fu4A:
undetectable		 3fl9A-6fu4A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_C_AICC375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 6fu4 PROBABLE CHEMOTAXIS
TRANSDUCER
(Pseudomonas
aeruginosa) 		6 / 11 GLY A  62
LEU A 318
SER A 306
LEU A 308
LEU A 333
LEU A 334
 None
 1.49A 3ndvC-6fu4A:
undetectable
3ndvD-6fu4A:
undetectable		 3ndvC-6fu4A:
12.64
3ndvD-6fu4A:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_D_AICD374_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 6fu4 PROBABLE CHEMOTAXIS
TRANSDUCER
(Pseudomonas
aeruginosa) 		6 / 11 LEU A 333
LEU A 334
GLY A  62
LEU A 318
SER A 306
LEU A 308
 None
 1.50A 3ndvC-6fu4A:
undetectable
3ndvD-6fu4A:
undetectable		 3ndvC-6fu4A:
12.64
3ndvD-6fu4A:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA402_1
(HIV-1 PROTEASE)		 6fu4 PROBABLE CHEMOTAXIS
TRANSDUCER
(Pseudomonas
aeruginosa) 		4 / 5 ARG A  61
LEU A 334
PRO A 337
VAL A 336
 None
 1.01A 3ufnA-6fu4A:
undetectable
3ufnB-6fu4A:
undetectable		 3ufnA-6fu4A:
15.31
3ufnB-6fu4A:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_CQAB303_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 6fu4 PROBABLE CHEMOTAXIS
TRANSDUCER
(Pseudomonas
aeruginosa) 		4 / 8 GLY A 148
GLY A 153
GLU A 139
LEU A 140
 None
 0.76A 4mwzB-6fu4A:
undetectable		 4mwzB-6fu4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_A_AG2A506_1
(HOMOSPERMIDINE
SYNTHASE)		 6fu4 PROBABLE CHEMOTAXIS
TRANSDUCER
(Pseudomonas
aeruginosa) 		4 / 6 ARG A 105
ARG A  91
ASP A 135
VAL A 127
 None
 1.40A 4xqeA-6fu4A:
undetectable		 4xqeA-6fu4A:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 6fu4 PROBABLE CHEMOTAXIS
TRANSDUCER
(Pseudomonas
aeruginosa) 		4 / 6 ARG A 105
ARG A  91
ASP A 135
VAL A 127
 None
 1.40A 4xqeB-6fu4A:
undetectable		 4xqeB-6fu4A:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_E_SAME301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 6fu4 PROBABLE CHEMOTAXIS
TRANSDUCER
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 274
GLY A 331
LEU A 266
ALA A 247
LEU A 282
 None
 1.09A 5c0oE-6fu4A:
undetectable		 5c0oE-6fu4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 6fu4 PROBABLE CHEMOTAXIS
TRANSDUCER
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 200
PHE A 224
SER A  84
PHE A 129
GLU A 130
 None
 1.16A 5cprB-6fu4A:
undetectable		 5cprB-6fu4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 6fu4 PROBABLE CHEMOTAXIS
TRANSDUCER
(Pseudomonas
aeruginosa) 		4 / 8 THR A 194
ALA A 187
ASP A 206
SER A 185
 None
 1.07A 5l5fY-6fu4A:
undetectable
5l5fZ-6fu4A:
0.6		 5l5fY-6fu4A:
12.80
5l5fZ-6fu4A:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_1_PQN1842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 6fu4 PROBABLE CHEMOTAXIS
TRANSDUCER
(Pseudomonas
aeruginosa) 		5 / 10 PHE A 272
ALA A 287
LEU A 286
GLY A 270
LEU A 341
 None
 1.27A 5oy01-6fu4A:
undetectable
5oy07-6fu4A:
undetectable		 5oy01-6fu4A:
20.51
5oy07-6fu4A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_1_PQN1842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 6fu4 PROBABLE CHEMOTAXIS
TRANSDUCER
(Pseudomonas
aeruginosa) 		5 / 10 PHE A 272
ALA A 294
LEU A 286
GLY A 270
LEU A 341
 None
 1.17A 5oy01-6fu4A:
undetectable
5oy07-6fu4A:
undetectable		 5oy01-6fu4A:
20.51
5oy07-6fu4A:
22.37