SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fur'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_B_CCSB417_0
(ESTROGEN RECEPTOR)		 6fur HUMAN F11 T-CELL
RECEPTOR
(Homo
sapiens) 		4 / 6 PRO B 119
PHE B 210
GLU B 152
GLN B 229
 None
 1.07A 1l2iB-6furB:
undetectable		 1l2iB-6furB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)		 6fur HUMAN F11 T-CELL
RECEPTOR
(Homo
sapiens) 		4 / 6 ILE B  18
PRO B 148
LEU B 113
ILE B  11
 None
None
SO4  B 305 (-4.1A)
GOL  B 307 (-4.4A)
 1.03A 2q83B-6furB:
undetectable		 2q83B-6furB:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 6fur HUMAN F11 T-CELL
RECEPTOR
(Homo
sapiens) 		5 / 12 HIS B 150
ILE B  11
THR B  12
VAL B 110
PRO B 148
 None
GOL  B 307 (-4.4A)
None
None
None
 1.20A 3kpbC-6furB:
undetectable		 3kpbC-6furB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_A_P1BA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 6fur HUMAN F11 T-CELL
RECEPTOR
(Homo
sapiens) 		5 / 12 PRO B   7
LEU B  75
ILE B  18
GLN B  84
TYR B  88
 GOL  B 306 ( 4.8A)
None
None
None
None
 1.46A 4a79A-6furB:
undetectable		 4a79A-6furB:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_B_P1BB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 6fur HUMAN F11 T-CELL
RECEPTOR
(Homo
sapiens) 		5 / 12 PRO B   7
LEU B  75
ILE B  18
GLN B  84
TYR B  88
 GOL  B 306 ( 4.8A)
None
None
None
None
 1.44A 4a79B-6furB:
undetectable		 4a79B-6furB:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_J_EDTJ301_0
(TCRBETA CHAIN)		 6fur HUMAN F11 T-CELL
RECEPTOR
(Homo
sapiens) 		4 / 5 TYR B  46
LYS B  56
GLY B  62
SER B  64
 None
None
None
EDO  B 302 (-3.3A)
 0.62A 5jhdJ-6furB:
29.4		 5jhdJ-6furB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 6fur HUMAN F11 T-CELL
RECEPTOR
(Homo
sapiens) 		4 / 5 TYR B  63
SER B  79
ALA B  80
THR B  12
 None
 1.37A 5n0wB-6furB:
undetectable		 5n0wB-6furB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 6fur HUMAN F11 T-CELL
RECEPTOR
(Homo
sapiens) 		4 / 5 TYR B  63
SER B  79
ALA B  80
THR B  12
 None
 1.39A 5n4iA-6furB:
undetectable		 5n4iA-6furB:
undetectable