SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fuw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_A_CUA1599_0
(NITROUS OXIDE
REDUCTASE)		 6fuw CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 4
(Homo
sapiens) 		3 / 3 CYH C  82
CYH C  68
HIS C  86
 ZN  C 202 (-2.2A)
ZN  C 202 (-2.3A)
ZN  C 202 (-3.3A)
 0.87A 2iwkA-6fuwC:
undetectable		 2iwkA-6fuwC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_A_CUA1599_0
(NITROUS OXIDE
REDUCTASE)		 6fuw CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 4
(Homo
sapiens) 		3 / 3 CYH C 110
CYH C  96
HIS C 114
 ZN  C 203 (-2.4A)
ZN  C 203 (-2.2A)
ZN  C 203 (-3.1A)
 0.87A 2iwkA-6fuwC:
undetectable		 2iwkA-6fuwC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_B_CUB1599_0
(NITROUS OXIDE
REDUCTASE)		 6fuw CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 4
(Homo
sapiens) 		3 / 3 CYH C  82
CYH C  68
HIS C  86
 ZN  C 202 (-2.2A)
ZN  C 202 (-2.3A)
ZN  C 202 (-3.3A)
 0.85A 2iwkB-6fuwC:
undetectable		 2iwkB-6fuwC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_B_CUB1599_0
(NITROUS OXIDE
REDUCTASE)		 6fuw CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 4
(Homo
sapiens) 		3 / 3 CYH C 110
CYH C  96
HIS C 114
 ZN  C 203 (-2.4A)
ZN  C 203 (-2.2A)
ZN  C 203 (-3.1A)
 0.86A 2iwkB-6fuwC:
undetectable		 2iwkB-6fuwC:
undetectable