SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fuy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD8_0
(GRAMICIDIN A)		 6fuy VINCULIN
(Homo
sapiens) 		3 / 3 VAL A 706
VAL A 665
TRP A 702
 None
 0.78A 1av2C-6fuyA:
undetectable
1av2D-6fuyA:
undetectable		 1av2C-6fuyA:
undetectable
1av2D-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B02_A_C2FA281_0
(PROTEIN (THYMIDYLATE
SYNTHASE))		 6fuy VINCULIN
(Homo
sapiens) 		5 / 11 ALA A 353
ILE A 299
LEU A 328
GLY A 329
ALA A 306
 None
 0.85A 1b02A-6fuyA:
undetectable		 1b02A-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.22A 1c9sA-6fuyA:
undetectable
1c9sK-6fuyA:
undetectable		 1c9sA-6fuyA:
undetectable
1c9sK-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.21A 1c9sA-6fuyA:
undetectable
1c9sB-6fuyA:
undetectable		 1c9sA-6fuyA:
undetectable
1c9sB-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.22A 1c9sB-6fuyA:
undetectable
1c9sC-6fuyA:
undetectable		 1c9sB-6fuyA:
undetectable
1c9sC-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.22A 1c9sC-6fuyA:
undetectable
1c9sD-6fuyA:
undetectable		 1c9sC-6fuyA:
undetectable
1c9sD-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 1c9sD-6fuyA:
undetectable
1c9sE-6fuyA:
undetectable		 1c9sD-6fuyA:
undetectable
1c9sE-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.22A 1c9sE-6fuyA:
undetectable
1c9sF-6fuyA:
undetectable		 1c9sE-6fuyA:
undetectable
1c9sF-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.22A 1c9sF-6fuyA:
undetectable
1c9sG-6fuyA:
undetectable		 1c9sF-6fuyA:
undetectable
1c9sG-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.22A 1c9sG-6fuyA:
undetectable
1c9sH-6fuyA:
undetectable		 1c9sG-6fuyA:
undetectable
1c9sH-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.24A 1c9sH-6fuyA:
undetectable
1c9sI-6fuyA:
undetectable		 1c9sH-6fuyA:
undetectable
1c9sI-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.20A 1c9sJ-6fuyA:
undetectable
1c9sK-6fuyA:
undetectable		 1c9sJ-6fuyA:
undetectable
1c9sK-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXH_B_PACB1001_0
(PENICILLIN ACYLASE)		 6fuy VINCULIN
(Homo
sapiens) 		4 / 7 PHE A 779
PHE A 835
SER A 787
ALA A 782
 None
 0.83A 1fxhA-6fuyA:
undetectable
1fxhB-6fuyA:
2.1		 1fxhA-6fuyA:
undetectable
1fxhB-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.22A 1gtfA-6fuyA:
undetectable
1gtfK-6fuyA:
undetectable		 1gtfA-6fuyA:
undetectable
1gtfK-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.20A 1gtfA-6fuyA:
undetectable
1gtfB-6fuyA:
undetectable		 1gtfA-6fuyA:
undetectable
1gtfB-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.22A 1gtfB-6fuyA:
undetectable
1gtfC-6fuyA:
undetectable		 1gtfB-6fuyA:
undetectable
1gtfC-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.22A 1gtfC-6fuyA:
undetectable
1gtfD-6fuyA:
undetectable		 1gtfC-6fuyA:
undetectable
1gtfD-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 1gtfE-6fuyA:
undetectable
1gtfF-6fuyA:
undetectable		 1gtfE-6fuyA:
undetectable
1gtfF-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.22A 1gtfF-6fuyA:
undetectable
1gtfG-6fuyA:
undetectable		 1gtfF-6fuyA:
undetectable
1gtfG-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.21A 1gtfG-6fuyA:
undetectable
1gtfH-6fuyA:
undetectable		 1gtfG-6fuyA:
undetectable
1gtfH-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.21A 1gtfH-6fuyA:
undetectable
1gtfI-6fuyA:
undetectable		 1gtfH-6fuyA:
undetectable
1gtfI-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.20A 1gtfI-6fuyA:
undetectable
1gtfJ-6fuyA:
undetectable		 1gtfI-6fuyA:
undetectable
1gtfJ-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.22A 1gtnB-6fuyA:
undetectable
1gtnC-6fuyA:
undetectable		 1gtnB-6fuyA:
undetectable
1gtnC-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.20A 1gtnG-6fuyA:
undetectable
1gtnH-6fuyA:
undetectable		 1gtnG-6fuyA:
undetectable
1gtnH-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 ARG A 520
ALA A 518
ALA A 500
THR A 552
ILE A 504
 None
 1.22A 1gtnH-6fuyA:
undetectable
1gtnI-6fuyA:
undetectable		 1gtnH-6fuyA:
undetectable
1gtnI-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.22A 1gtnH-6fuyA:
undetectable
1gtnI-6fuyA:
undetectable		 1gtnH-6fuyA:
undetectable
1gtnI-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_B_HISB450_0
(HISTIDYL-TRNA
SYNTHETASE)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 12 GLU A 305
GLN A 301
GLU A 645
GLY A 638
GLY A 641
 None
 1.07A 1httB-6fuyA:
undetectable		 1httB-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_C_HISC450_0
(HISTIDYL-TRNA
SYNTHETASE)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 12 GLU A 305
GLN A 301
GLU A 645
GLY A 638
GLY A 641
 None
 1.09A 1httC-6fuyA:
undetectable		 1httC-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_D_HISD450_0
(HISTIDYL-TRNA
SYNTHETASE)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 12 GLU A 305
GLN A 301
GLU A 645
GLY A 638
GLY A 641
 None
 1.06A 1httD-6fuyA:
undetectable		 1httD-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JFF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 12 VAL A  24
GLU A  28
LEU A1023
THR A1020
GLY A1007
 None
 1.11A 1jffB-6fuyA:
undetectable		 1jffB-6fuyA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 1utdA-6fuyA:
undetectable
1utdB-6fuyA:
undetectable		 1utdA-6fuyA:
undetectable
1utdB-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.24A 1utdC-6fuyA:
undetectable
1utdD-6fuyA:
undetectable		 1utdC-6fuyA:
undetectable
1utdD-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.21A 1utdD-6fuyA:
undetectable
1utdE-6fuyA:
undetectable		 1utdD-6fuyA:
undetectable
1utdE-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.20A 1utdG-6fuyA:
undetectable
1utdH-6fuyA:
undetectable		 1utdG-6fuyA:
undetectable
1utdH-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_K_TRPK81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.21A 1utdA-6fuyA:
undetectable
1utdK-6fuyA:
undetectable		 1utdA-6fuyA:
undetectable
1utdK-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.20A 1utdN-6fuyA:
undetectable
1utdO-6fuyA:
undetectable		 1utdN-6fuyA:
undetectable
1utdO-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_D_DVAD8_0
(GRAMICIDIN D)		 6fuy VINCULIN
(Homo
sapiens) 		3 / 3 VAL A 706
VAL A 665
TRP A 702
 None
 0.71A 1w5uC-6fuyA:
undetectable
1w5uD-6fuyA:
undetectable		 1w5uC-6fuyA:
undetectable
1w5uD-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_2
(RETINOIC ACID
RECEPTOR, BETA)		 6fuy VINCULIN
(Homo
sapiens) 		3 / 3 LEU A 818
PHE A 817
ARG A 759
 None
 0.83A 1xdkF-6fuyA:
undetectable		 1xdkF-6fuyA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 12 HIS A  22
ILE A  20
LEU A 108
ASP A  33
VAL A  32
 None
 1.19A 1zq9A-6fuyA:
undetectable		 1zq9A-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_A_THRA401_0
(ASPARTOKINASE)		 6fuy VINCULIN
(Homo
sapiens) 		4 / 8 GLU A1042
ALA A1041
ASN A 917
ILE A 919
 None
 0.77A 2dtjA-6fuyA:
undetectable
2dtjB-6fuyA:
undetectable		 2dtjA-6fuyA:
undetectable
2dtjB-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 12 VAL A  24
GLU A  28
LEU A1023
THR A1020
GLY A1007
 None
 1.11A 2hxfB-6fuyA:
undetectable		 2hxfB-6fuyA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXH_B_TA1B601_1
(TUBULIN BETA CHAIN)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 12 VAL A  24
GLU A  28
LEU A1023
THR A1020
GLY A1007
 None
 1.11A 2hxhB-6fuyA:
undetectable		 2hxhB-6fuyA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA8_0
(GRAMICIDIN D)		 6fuy VINCULIN
(Homo
sapiens) 		3 / 3 VAL A 665
TRP A 702
VAL A 706
 None
 0.79A 2izqA-6fuyA:
undetectable
2izqB-6fuyA:
undetectable		 2izqA-6fuyA:
undetectable
2izqB-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J7X_A_ESTA1454_1
(ESTROGEN RECEPTOR
BETA)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 12 LEU A 277
LEU A 270
ILE A 321
GLY A 307
LEU A 303
 None
 1.30A 2j7xA-6fuyA:
undetectable		 2j7xA-6fuyA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 12 VAL A 131
THR A 125
LEU A 182
THR A   6
HIS A   5
 None
 1.29A 2jn3A-6fuyA:
undetectable		 2jn3A-6fuyA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KUH_A_HLTA150_1
(CALMODULIN)		 6fuy VINCULIN
(Homo
sapiens) 		4 / 6 MET A 168
LEU A 202
MET A 237
GLU A 240
 None
 1.24A 2kuhA-6fuyA:
undetectable		 2kuhA-6fuyA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P4N_B_TA1B601_1
(TUBULIN BETA CHAIN)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 12 VAL A  24
GLU A  28
LEU A1023
THR A1020
GLY A1007
 None
 1.11A 2p4nB-6fuyA:
undetectable		 2p4nB-6fuyA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_A_RBFA200_1
(DODECIN)		 6fuy VINCULIN
(Homo
sapiens) 		4 / 8 TRP A 253
GLN A 994
ARG A 987
HIS A 187
 None
 1.31A 2vxaA-6fuyA:
undetectable
2vxaC-6fuyA:
undetectable
2vxaE-6fuyA:
undetectable		 2vxaA-6fuyA:
24.71
2vxaC-6fuyA:
24.71
2vxaE-6fuyA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_B_RBFB200_1
(DODECIN)		 6fuy VINCULIN
(Homo
sapiens) 		4 / 8 GLN A 994
TRP A 253
ARG A 987
HIS A 187
 None
 1.30A 2vxaA-6fuyA:
undetectable
2vxaB-6fuyA:
undetectable
2vxaK-6fuyA:
undetectable		 2vxaA-6fuyA:
24.71
2vxaB-6fuyA:
24.71
2vxaK-6fuyA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_C_RBFC200_1
(DODECIN)		 6fuy VINCULIN
(Homo
sapiens) 		4 / 8 GLN A 994
TRP A 253
ARG A 987
HIS A 187
 None
 1.30A 2vxaB-6fuyA:
undetectable
2vxaC-6fuyA:
undetectable
2vxaG-6fuyA:
undetectable		 2vxaB-6fuyA:
24.71
2vxaC-6fuyA:
24.71
2vxaG-6fuyA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_D_RBFD200_1
(DODECIN)		 6fuy VINCULIN
(Homo
sapiens) 		4 / 8 TRP A 253
GLN A 994
ARG A 987
HIS A 187
 None
 1.33A 2vxaD-6fuyA:
undetectable
2vxaF-6fuyA:
undetectable
2vxaI-6fuyA:
undetectable		 2vxaD-6fuyA:
24.71
2vxaF-6fuyA:
24.71
2vxaI-6fuyA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_E_RBFE200_1
(DODECIN)		 6fuy VINCULIN
(Homo
sapiens) 		4 / 8 GLN A 994
TRP A 253
ARG A 987
HIS A 187
 None
 1.31A 2vxaD-6fuyA:
undetectable
2vxaE-6fuyA:
undetectable
2vxaL-6fuyA:
undetectable		 2vxaD-6fuyA:
24.71
2vxaE-6fuyA:
24.71
2vxaL-6fuyA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_G_RBFG200_1
(DODECIN)		 6fuy VINCULIN
(Homo
sapiens) 		4 / 8 ARG A 987
HIS A 187
TRP A 253
GLN A 994
 None
 1.28A 2vxaF-6fuyA:
undetectable
2vxaG-6fuyA:
undetectable
2vxaI-6fuyA:
undetectable		 2vxaF-6fuyA:
24.71
2vxaG-6fuyA:
24.71
2vxaI-6fuyA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_H_RBFH200_1
(DODECIN)		 6fuy VINCULIN
(Homo
sapiens) 		4 / 8 ARG A 987
HIS A 187
GLN A 994
TRP A 253
 None
 1.31A 2vxaB-6fuyA:
undetectable
2vxaG-6fuyA:
undetectable
2vxaH-6fuyA:
undetectable		 2vxaB-6fuyA:
24.71
2vxaG-6fuyA:
24.71
2vxaH-6fuyA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_I_RBFI200_1
(DODECIN)		 6fuy VINCULIN
(Homo
sapiens) 		4 / 8 GLN A 994
TRP A 253
ARG A 987
HIS A 187
 None
 1.28A 2vxaH-6fuyA:
undetectable
2vxaI-6fuyA:
undetectable
2vxaJ-6fuyA:
undetectable		 2vxaH-6fuyA:
24.71
2vxaI-6fuyA:
24.71
2vxaJ-6fuyA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_J_RBFJ200_1
(DODECIN)		 6fuy VINCULIN
(Homo
sapiens) 		4 / 8 ARG A 987
HIS A 187
TRP A 253
GLN A 994
 None
 1.33A 2vxaD-6fuyA:
undetectable
2vxaJ-6fuyA:
undetectable
2vxaL-6fuyA:
undetectable		 2vxaD-6fuyA:
24.71
2vxaJ-6fuyA:
24.71
2vxaL-6fuyA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_K_RBFK200_1
(DODECIN)		 6fuy VINCULIN
(Homo
sapiens) 		4 / 8 ARG A 987
HIS A 187
GLN A 994
TRP A 253
 None
 1.28A 2vxaH-6fuyA:
undetectable
2vxaJ-6fuyA:
undetectable
2vxaK-6fuyA:
undetectable		 2vxaH-6fuyA:
24.71
2vxaJ-6fuyA:
24.71
2vxaK-6fuyA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_L_RBFL200_1
(DODECIN)		 6fuy VINCULIN
(Homo
sapiens) 		4 / 8 ARG A 987
HIS A 187
GLN A 994
TRP A 253
 None
 1.29A 2vxaA-6fuyA:
undetectable
2vxaK-6fuyA:
undetectable
2vxaL-6fuyA:
undetectable		 2vxaA-6fuyA:
24.71
2vxaK-6fuyA:
24.71
2vxaL-6fuyA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WBE_B_TA1B1439_1
(TUBULIN BETA-2B
CHAIN)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 12 VAL A  24
GLU A  28
LEU A1023
THR A1020
GLY A1007
 None
 1.11A 2wbeB-6fuyA:
undetectable		 2wbeB-6fuyA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_2
(ANGIOTENSIN
CONVERTING ENZYME)		 6fuy VINCULIN
(Homo
sapiens) 		3 / 3 SER A 112
THR A 119
PHE A   4
 None
 0.65A 2x91A-6fuyA:
undetectable		 2x91A-6fuyA:
8.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCO_B_TA1B601_1
(BOVINE BETA TUBULIN)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 12 VAL A  24
GLU A  28
LEU A1023
THR A1020
GLY A1007
 None
 1.11A 3dcoB-6fuyA:
undetectable		 3dcoB-6fuyA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EDL_B_TA1B601_1
(BETA TUBULIN)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 12 VAL A  24
GLU A  28
LEU A1023
THR A1020
GLY A1007
 None
 1.10A 3edlB-6fuyA:
undetectable		 3edlB-6fuyA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IZ0_B_TA1B820_1
(BETA TUBULIN, CHAIN
B FROM PDB 1JFF)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 12 VAL A  24
GLU A  28
LEU A1023
THR A1020
GLY A1007
 None
 1.11A 3iz0B-6fuyA:
undetectable		 3iz0B-6fuyA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB8_0
(GRAMICIDIN D)		 6fuy VINCULIN
(Homo
sapiens) 		3 / 3 VAL A 706
VAL A 665
TRP A 702
 None
 0.86A 3l8lA-6fuyA:
undetectable
3l8lB-6fuyA:
undetectable		 3l8lA-6fuyA:
undetectable
3l8lB-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD8_0
(GRAMICIDIN D)		 6fuy VINCULIN
(Homo
sapiens) 		3 / 3 VAL A 706
VAL A 665
TRP A 702
 None
 0.62A 3l8lC-6fuyA:
undetectable
3l8lD-6fuyA:
undetectable		 3l8lC-6fuyA:
undetectable
3l8lD-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXV_D_MTXD2000_2
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 6fuy VINCULIN
(Homo
sapiens) 		3 / 3 LEU A 609
ARG A 684
ASN A 229
 None
 0.62A 3qxvD-6fuyA:
undetectable		 3qxvD-6fuyA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1480_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 6fuy VINCULIN
(Homo
sapiens) 		4 / 4 LYS A 386
GLU A 414
ILE A 384
SER A 383
 None
 1.35A 4acbC-6fuyA:
undetectable		 4acbC-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H1N_A_CGEA505_1
(CYTOCHROME P450 2B4)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 11 ILE A 273
ILE A 302
THR A 324
ILE A 321
VAL A 367
 None
 1.09A 4h1nA-6fuyA:
0.1		 4h1nA-6fuyA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7A_A_MXDA1002_1
(ANDROGEN RECEPTOR)		 6fuy VINCULIN
(Homo
sapiens) 		3 / 3 GLU A1042
TRP A 912
LYS A1047
 None
 1.42A 4k7aA-6fuyA:
0.4		 4k7aA-6fuyA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_MTLA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6fuy VINCULIN
(Homo
sapiens) 		4 / 6 GLU A 884
ARG A 910
ASP A 907
ARG A 903
 None
 1.18A 4kcnA-6fuyA:
undetectable		 4kcnA-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6fuy VINCULIN
(Homo
sapiens) 		4 / 6 GLU A 884
ARG A 910
ASP A 907
ARG A 903
 None
 1.15A 4kcnB-6fuyA:
undetectable		 4kcnB-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA208_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 6fuy VINCULIN
(Homo
sapiens) 		4 / 4 ALA A  42
ALA A  45
ALA A  46
ALA A  49
 None
 0.13A 4oaeA-6fuyA:
undetectable		 4oaeA-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)		 6fuy VINCULIN
(Homo
sapiens) 		3 / 3 MET A  94
MET A  26
TYR A 107
 None
 1.16A 4p6xI-6fuyA:
undetectable		 4p6xI-6fuyA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V20_A_ACTA1444_0
(CELLOBIOHYDROLASE)		 6fuy VINCULIN
(Homo
sapiens) 		4 / 5 GLY A 942
THR A 943
GLY A1007
GLU A  28
 None
 0.72A 4v20A-6fuyA:
undetectable		 4v20A-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WCX_C_SAMC503_1
(BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED)		 6fuy VINCULIN
(Homo
sapiens) 		4 / 6 ASN A 705
LEU A 671
GLU A 670
LYS A 236
 None
 1.39A 4wcxC-6fuyA:
undetectable		 4wcxC-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 6fuy VINCULIN
(Homo
sapiens) 		4 / 6 ARG A 136
ASP A  67
LYS A  71
ARG A  72
 None
 1.38A 5a06A-6fuyA:
undetectable		 5a06A-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 6fuy VINCULIN
(Homo
sapiens) 		4 / 5 ARG A 502
HIS A 492
ALA A 490
GLU A 498
 None
 1.23A 5a06C-6fuyA:
undetectable
5a06D-6fuyA:
undetectable		 5a06C-6fuyA:
undetectable
5a06D-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E3I_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 12 GLU A 305
GLN A 301
GLU A 645
GLY A 638
GLY A 641
 None
 1.16A 5e3iA-6fuyA:
undetectable		 5e3iA-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E3I_B_HISB502_0
(HISTIDINE--TRNA
LIGASE)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 11 GLU A 305
GLN A 301
GLU A 645
GLY A 638
GLY A 641
 None
 1.17A 5e3iB-6fuyA:
undetectable		 5e3iB-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.21A 5eeuA-6fuyA:
undetectable
5eeuB-6fuyA:
undetectable		 5eeuA-6fuyA:
undetectable
5eeuB-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.21A 5eeuB-6fuyA:
undetectable
5eeuC-6fuyA:
undetectable		 5eeuB-6fuyA:
undetectable
5eeuC-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5eeuC-6fuyA:
undetectable
5eeuD-6fuyA:
undetectable		 5eeuC-6fuyA:
undetectable
5eeuD-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.21A 5eeuD-6fuyA:
undetectable
5eeuE-6fuyA:
undetectable		 5eeuD-6fuyA:
undetectable
5eeuE-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5eeuE-6fuyA:
undetectable
5eeuF-6fuyA:
undetectable		 5eeuE-6fuyA:
undetectable
5eeuF-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5eeuG-6fuyA:
undetectable
5eeuH-6fuyA:
undetectable		 5eeuG-6fuyA:
undetectable
5eeuH-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.22A 5eeuH-6fuyA:
undetectable
5eeuI-6fuyA:
undetectable		 5eeuH-6fuyA:
undetectable
5eeuI-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5eeuJ-6fuyA:
undetectable
5eeuK-6fuyA:
undetectable		 5eeuJ-6fuyA:
undetectable
5eeuK-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5eeuA-6fuyA:
undetectable
5eeuK-6fuyA:
undetectable		 5eeuA-6fuyA:
undetectable
5eeuK-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5eeuS-6fuyA:
undetectable
5eeuT-6fuyA:
undetectable		 5eeuS-6fuyA:
undetectable
5eeuT-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.24A 5eeuT-6fuyA:
undetectable
5eeuU-6fuyA:
undetectable		 5eeuT-6fuyA:
undetectable
5eeuU-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.21A 5eevB-6fuyA:
undetectable
5eevC-6fuyA:
undetectable		 5eevB-6fuyA:
undetectable
5eevC-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5eevC-6fuyA:
undetectable
5eevD-6fuyA:
undetectable		 5eevC-6fuyA:
undetectable
5eevD-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.21A 5eevD-6fuyA:
undetectable
5eevE-6fuyA:
undetectable		 5eevD-6fuyA:
undetectable
5eevE-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5eevE-6fuyA:
undetectable
5eevF-6fuyA:
undetectable		 5eevE-6fuyA:
undetectable
5eevF-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.22A 5eevG-6fuyA:
undetectable
5eevH-6fuyA:
undetectable		 5eevG-6fuyA:
undetectable
5eevH-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.22A 5eevH-6fuyA:
undetectable
5eevI-6fuyA:
undetectable		 5eevH-6fuyA:
undetectable
5eevI-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5eevJ-6fuyA:
undetectable
5eevK-6fuyA:
undetectable		 5eevJ-6fuyA:
undetectable
5eevK-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5eevA-6fuyA:
undetectable
5eevK-6fuyA:
undetectable		 5eevA-6fuyA:
undetectable
5eevK-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5eevS-6fuyA:
undetectable
5eevT-6fuyA:
undetectable		 5eevS-6fuyA:
undetectable
5eevT-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.24A 5eevT-6fuyA:
undetectable
5eevU-6fuyA:
undetectable		 5eevT-6fuyA:
undetectable
5eevU-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.21A 5eewB-6fuyA:
undetectable
5eewC-6fuyA:
undetectable		 5eewB-6fuyA:
undetectable
5eewC-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5eewC-6fuyA:
undetectable
5eewD-6fuyA:
undetectable		 5eewC-6fuyA:
undetectable
5eewD-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.20A 5eewD-6fuyA:
undetectable
5eewE-6fuyA:
undetectable		 5eewD-6fuyA:
undetectable
5eewE-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5eewE-6fuyA:
undetectable
5eewF-6fuyA:
undetectable		 5eewE-6fuyA:
undetectable
5eewF-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5eewG-6fuyA:
undetectable
5eewH-6fuyA:
undetectable		 5eewG-6fuyA:
undetectable
5eewH-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.22A 5eewH-6fuyA:
undetectable
5eewI-6fuyA:
undetectable		 5eewH-6fuyA:
undetectable
5eewI-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.24A 5eewJ-6fuyA:
undetectable
5eewK-6fuyA:
undetectable		 5eewJ-6fuyA:
undetectable
5eewK-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5eewA-6fuyA:
undetectable
5eewK-6fuyA:
undetectable		 5eewA-6fuyA:
undetectable
5eewK-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5eewS-6fuyA:
undetectable
5eewT-6fuyA:
undetectable		 5eewS-6fuyA:
undetectable
5eewT-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.24A 5eewT-6fuyA:
undetectable
5eewU-6fuyA:
undetectable		 5eewT-6fuyA:
undetectable
5eewU-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.21A 5eexB-6fuyA:
undetectable
5eexC-6fuyA:
undetectable		 5eexB-6fuyA:
undetectable
5eexC-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5eexC-6fuyA:
undetectable
5eexD-6fuyA:
undetectable		 5eexC-6fuyA:
undetectable
5eexD-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.21A 5eexD-6fuyA:
undetectable
5eexE-6fuyA:
undetectable		 5eexD-6fuyA:
undetectable
5eexE-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5eexE-6fuyA:
undetectable
5eexF-6fuyA:
undetectable		 5eexE-6fuyA:
undetectable
5eexF-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.22A 5eexG-6fuyA:
undetectable
5eexH-6fuyA:
undetectable		 5eexG-6fuyA:
undetectable
5eexH-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.22A 5eexH-6fuyA:
undetectable
5eexI-6fuyA:
undetectable		 5eexH-6fuyA:
undetectable
5eexI-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 11 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.21A 5eexI-6fuyA:
undetectable
5eexJ-6fuyA:
undetectable		 5eexI-6fuyA:
undetectable
5eexJ-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.24A 5eexJ-6fuyA:
undetectable
5eexK-6fuyA:
undetectable		 5eexJ-6fuyA:
undetectable
5eexK-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5eexA-6fuyA:
undetectable
5eexK-6fuyA:
undetectable		 5eexA-6fuyA:
undetectable
5eexK-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5eexS-6fuyA:
undetectable
5eexT-6fuyA:
undetectable		 5eexS-6fuyA:
undetectable
5eexT-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.24A 5eexT-6fuyA:
undetectable
5eexU-6fuyA:
undetectable		 5eexT-6fuyA:
undetectable
5eexU-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.21A 5eeyB-6fuyA:
undetectable
5eeyC-6fuyA:
undetectable		 5eeyB-6fuyA:
undetectable
5eeyC-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5eeyC-6fuyA:
undetectable
5eeyD-6fuyA:
undetectable		 5eeyC-6fuyA:
undetectable
5eeyD-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.20A 5eeyD-6fuyA:
undetectable
5eeyE-6fuyA:
undetectable		 5eeyD-6fuyA:
undetectable
5eeyE-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5eeyE-6fuyA:
undetectable
5eeyF-6fuyA:
undetectable		 5eeyE-6fuyA:
undetectable
5eeyF-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.22A 5eeyG-6fuyA:
undetectable
5eeyH-6fuyA:
undetectable		 5eeyG-6fuyA:
undetectable
5eeyH-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.22A 5eeyH-6fuyA:
undetectable
5eeyI-6fuyA:
undetectable		 5eeyH-6fuyA:
undetectable
5eeyI-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 11 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.22A 5eeyI-6fuyA:
undetectable
5eeyJ-6fuyA:
undetectable		 5eeyI-6fuyA:
undetectable
5eeyJ-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5eeyJ-6fuyA:
undetectable
5eeyK-6fuyA:
undetectable		 5eeyJ-6fuyA:
undetectable
5eeyK-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5eeyA-6fuyA:
undetectable
5eeyK-6fuyA:
undetectable		 5eeyA-6fuyA:
undetectable
5eeyK-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5eeyS-6fuyA:
undetectable
5eeyT-6fuyA:
undetectable		 5eeyS-6fuyA:
undetectable
5eeyT-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.24A 5eeyT-6fuyA:
undetectable
5eeyU-6fuyA:
undetectable		 5eeyT-6fuyA:
undetectable
5eeyU-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.21A 5eezB-6fuyA:
undetectable
5eezC-6fuyA:
undetectable		 5eezB-6fuyA:
undetectable
5eezC-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5eezC-6fuyA:
undetectable
5eezD-6fuyA:
undetectable		 5eezC-6fuyA:
undetectable
5eezD-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.20A 5eezD-6fuyA:
undetectable
5eezE-6fuyA:
undetectable		 5eezD-6fuyA:
undetectable
5eezE-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.22A 5eezE-6fuyA:
undetectable
5eezF-6fuyA:
undetectable		 5eezE-6fuyA:
undetectable
5eezF-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5eezG-6fuyA:
undetectable
5eezH-6fuyA:
undetectable		 5eezG-6fuyA:
undetectable
5eezH-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.22A 5eezH-6fuyA:
undetectable
5eezI-6fuyA:
undetectable		 5eezH-6fuyA:
undetectable
5eezI-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 11 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.22A 5eezI-6fuyA:
undetectable
5eezJ-6fuyA:
undetectable		 5eezI-6fuyA:
undetectable
5eezJ-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.24A 5eezJ-6fuyA:
undetectable
5eezK-6fuyA:
undetectable		 5eezJ-6fuyA:
undetectable
5eezK-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5eezA-6fuyA:
undetectable
5eezK-6fuyA:
undetectable		 5eezA-6fuyA:
undetectable
5eezK-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.24A 5eezS-6fuyA:
undetectable
5eezT-6fuyA:
undetectable		 5eezS-6fuyA:
undetectable
5eezT-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.24A 5eezT-6fuyA:
undetectable
5eezU-6fuyA:
undetectable		 5eezT-6fuyA:
undetectable
5eezU-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.21A 5ef0B-6fuyA:
undetectable
5ef0C-6fuyA:
undetectable		 5ef0B-6fuyA:
undetectable
5ef0C-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5ef0C-6fuyA:
undetectable
5ef0D-6fuyA:
undetectable		 5ef0C-6fuyA:
undetectable
5ef0D-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.21A 5ef0D-6fuyA:
undetectable
5ef0E-6fuyA:
undetectable		 5ef0D-6fuyA:
undetectable
5ef0E-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5ef0E-6fuyA:
undetectable
5ef0F-6fuyA:
undetectable		 5ef0E-6fuyA:
undetectable
5ef0F-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.22A 5ef0G-6fuyA:
undetectable
5ef0H-6fuyA:
undetectable		 5ef0G-6fuyA:
undetectable
5ef0H-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.22A 5ef0H-6fuyA:
undetectable
5ef0I-6fuyA:
undetectable		 5ef0H-6fuyA:
undetectable
5ef0I-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 11 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.21A 5ef0I-6fuyA:
undetectable
5ef0J-6fuyA:
undetectable		 5ef0I-6fuyA:
undetectable
5ef0J-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5ef0J-6fuyA:
undetectable
5ef0K-6fuyA:
undetectable		 5ef0J-6fuyA:
undetectable
5ef0K-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5ef0A-6fuyA:
undetectable
5ef0K-6fuyA:
undetectable		 5ef0A-6fuyA:
undetectable
5ef0K-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5ef0S-6fuyA:
undetectable
5ef0T-6fuyA:
undetectable		 5ef0S-6fuyA:
undetectable
5ef0T-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5ef0T-6fuyA:
undetectable
5ef0U-6fuyA:
undetectable		 5ef0T-6fuyA:
undetectable
5ef0U-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.21A 5ef1B-6fuyA:
undetectable
5ef1C-6fuyA:
undetectable		 5ef1B-6fuyA:
undetectable
5ef1C-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5ef1C-6fuyA:
undetectable
5ef1D-6fuyA:
undetectable		 5ef1C-6fuyA:
undetectable
5ef1D-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.21A 5ef1D-6fuyA:
undetectable
5ef1E-6fuyA:
undetectable		 5ef1D-6fuyA:
undetectable
5ef1E-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5ef1E-6fuyA:
undetectable
5ef1F-6fuyA:
undetectable		 5ef1E-6fuyA:
undetectable
5ef1F-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5ef1G-6fuyA:
undetectable
5ef1H-6fuyA:
undetectable		 5ef1G-6fuyA:
undetectable
5ef1H-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.22A 5ef1H-6fuyA:
undetectable
5ef1I-6fuyA:
undetectable		 5ef1H-6fuyA:
undetectable
5ef1I-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 11 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.21A 5ef1I-6fuyA:
undetectable
5ef1J-6fuyA:
undetectable		 5ef1I-6fuyA:
undetectable
5ef1J-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.24A 5ef1J-6fuyA:
undetectable
5ef1K-6fuyA:
undetectable		 5ef1J-6fuyA:
undetectable
5ef1K-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5ef1A-6fuyA:
undetectable
5ef1K-6fuyA:
undetectable		 5ef1A-6fuyA:
undetectable
5ef1K-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5ef1S-6fuyA:
undetectable
5ef1T-6fuyA:
undetectable		 5ef1S-6fuyA:
undetectable
5ef1T-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5ef1T-6fuyA:
undetectable
5ef1U-6fuyA:
undetectable		 5ef1T-6fuyA:
undetectable
5ef1U-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.21A 5ef2B-6fuyA:
undetectable
5ef2C-6fuyA:
undetectable		 5ef2B-6fuyA:
undetectable
5ef2C-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5ef2C-6fuyA:
undetectable
5ef2D-6fuyA:
undetectable		 5ef2C-6fuyA:
undetectable
5ef2D-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.21A 5ef2D-6fuyA:
undetectable
5ef2E-6fuyA:
undetectable		 5ef2D-6fuyA:
undetectable
5ef2E-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5ef2E-6fuyA:
undetectable
5ef2F-6fuyA:
undetectable		 5ef2E-6fuyA:
undetectable
5ef2F-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5ef2G-6fuyA:
undetectable
5ef2H-6fuyA:
undetectable		 5ef2G-6fuyA:
undetectable
5ef2H-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.22A 5ef2H-6fuyA:
undetectable
5ef2I-6fuyA:
undetectable		 5ef2H-6fuyA:
undetectable
5ef2I-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 11 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.21A 5ef2I-6fuyA:
undetectable
5ef2J-6fuyA:
undetectable		 5ef2I-6fuyA:
undetectable
5ef2J-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5ef2J-6fuyA:
undetectable
5ef2K-6fuyA:
undetectable		 5ef2J-6fuyA:
undetectable
5ef2K-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5ef2A-6fuyA:
undetectable
5ef2K-6fuyA:
undetectable		 5ef2A-6fuyA:
undetectable
5ef2K-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5ef2S-6fuyA:
undetectable
5ef2T-6fuyA:
undetectable		 5ef2S-6fuyA:
undetectable
5ef2T-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.24A 5ef2T-6fuyA:
undetectable
5ef2U-6fuyA:
undetectable		 5ef2T-6fuyA:
undetectable
5ef2U-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.21A 5ef3B-6fuyA:
undetectable
5ef3C-6fuyA:
undetectable		 5ef3B-6fuyA:
undetectable
5ef3C-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5ef3C-6fuyA:
undetectable
5ef3D-6fuyA:
undetectable		 5ef3C-6fuyA:
undetectable
5ef3D-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.21A 5ef3D-6fuyA:
undetectable
5ef3E-6fuyA:
undetectable		 5ef3D-6fuyA:
undetectable
5ef3E-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.22A 5ef3E-6fuyA:
undetectable
5ef3F-6fuyA:
undetectable		 5ef3E-6fuyA:
undetectable
5ef3F-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.22A 5ef3G-6fuyA:
undetectable
5ef3H-6fuyA:
undetectable		 5ef3G-6fuyA:
undetectable
5ef3H-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.22A 5ef3H-6fuyA:
undetectable
5ef3I-6fuyA:
undetectable		 5ef3H-6fuyA:
undetectable
5ef3I-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 11 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.21A 5ef3I-6fuyA:
undetectable
5ef3J-6fuyA:
undetectable		 5ef3I-6fuyA:
undetectable
5ef3J-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 9 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.24A 5ef3J-6fuyA:
undetectable
5ef3K-6fuyA:
undetectable		 5ef3J-6fuyA:
undetectable
5ef3K-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5ef3A-6fuyA:
undetectable
5ef3K-6fuyA:
undetectable		 5ef3A-6fuyA:
undetectable
5ef3K-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5ef3S-6fuyA:
undetectable
5ef3T-6fuyA:
undetectable		 5ef3S-6fuyA:
undetectable
5ef3T-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 10 GLY A 222
ALA A 691
THR A 214
THR A 215
ILE A 681
 None
 1.23A 5ef3T-6fuyA:
undetectable
5ef3U-6fuyA:
undetectable		 5ef3T-6fuyA:
undetectable
5ef3U-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 12 LEU A 248
LEU A 201
MET A 171
GLU A 240
CYH A 138
 None
 1.47A 5emlA-6fuyA:
undetectable		 5emlA-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 6fuy VINCULIN
(Homo
sapiens) 		4 / 4 SER A 207
ALA A 208
GLN A 674
THR A 233
 None
 1.37A 5n0rA-6fuyA:
undetectable		 5n0rA-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 6fuy VINCULIN
(Homo
sapiens) 		4 / 4 SER A 207
ALA A 208
GLN A 674
THR A 233
 None
 1.34A 5n0sA-6fuyA:
undetectable		 5n0sA-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 6fuy VINCULIN
(Homo
sapiens) 		4 / 5 SER A 207
ALA A 208
GLN A 674
THR A 233
 None
 1.39A 5n0tA-6fuyA:
undetectable		 5n0tA-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 6fuy VINCULIN
(Homo
sapiens) 		4 / 4 SER A 207
ALA A 208
GLN A 674
THR A 233
 None
 1.33A 5n0wA-6fuyA:
undetectable		 5n0wA-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 6fuy VINCULIN
(Homo
sapiens) 		4 / 5 SER A 207
ALA A 208
GLN A 674
THR A 233
 None
 1.33A 5n0wB-6fuyA:
undetectable		 5n0wB-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 6fuy VINCULIN
(Homo
sapiens) 		4 / 4 SER A 207
ALA A 208
GLN A 674
THR A 233
 None
 1.36A 5n0xA-6fuyA:
undetectable		 5n0xA-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 6fuy VINCULIN
(Homo
sapiens) 		4 / 5 SER A 207
ALA A 208
GLN A 674
THR A 233
 None
 1.35A 5n4iA-6fuyA:
undetectable		 5n4iA-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_C_SAMC201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 12 LEU A 936
GLY A 940
LEU A1006
LYS A1002
SER A 934
 None
 1.16A 5twjC-6fuyA:
undetectable		 5twjC-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA502_1
(CYTOCHROME P450 2C9)		 6fuy VINCULIN
(Homo
sapiens) 		5 / 12 LEU A 529
VAL A 532
ASP A 597
THR A 710
LEU A 722
 None
 1.20A 5x24A-6fuyA:
undetectable		 5x24A-6fuyA:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW2_A_ACTA511_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 6fuy VINCULIN
(Homo
sapiens) 		3 / 3 ARG A 759
ILE A 730
SER A 726
 None
 0.77A 5zw2A-6fuyA:
3.4		 5zw2A-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EF6_A_ACTA405_0
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 6fuy VINCULIN
(Homo
sapiens) 		4 / 6 THR A 993
PRO A  15
GLN A  18
ILE A 997
 None
 1.34A 6ef6A-6fuyA:
1.6		 6ef6A-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA813_0
(GEPHYRIN)		 6fuy VINCULIN
(Homo
sapiens) 		3 / 3 THR A 215
ALA A 226
LYS A 228
 None
 0.68A 6fgcA-6fuyA:
undetectable		 6fgcA-6fuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA817_0
(GEPHYRIN)		 6fuy VINCULIN
(Homo
sapiens) 		3 / 3 THR A 215
ALA A 226
LYS A 228
 None
 0.68A 6fgdA-6fuyA:
undetectable		 6fgdA-6fuyA:
undetectable