SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fuz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC8_0
(ACTINOMYCIN D)		 6fuz KINESIN LIGHT CHAIN
1,KINESIN LIGHT
CHAIN
1,C-JUN-AMINO-TERMIN
AL
KINASE-INTERACTING
PROTEIN 1
(Homo
sapiens;
Mus
musculus) 		3 / 3 THR A 462
THR A 464
PRO A 461
 None
 0.80A 1dscC-6fuzA:
undetectable		 1dscC-6fuzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)		 6fuz KINESIN LIGHT CHAIN
1,KINESIN LIGHT
CHAIN
1,C-JUN-AMINO-TERMIN
AL
KINASE-INTERACTING
PROTEIN 1
(Homo
sapiens;
Mus
musculus) 		4 / 6 ALA A 239
SER A 225
ARG A 214
LEU A 243
 None
 1.17A 1gahA-6fuzA:
3.8		 1gahA-6fuzA:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)		 6fuz KINESIN LIGHT CHAIN
1,KINESIN LIGHT
CHAIN
1,C-JUN-AMINO-TERMIN
AL
KINASE-INTERACTING
PROTEIN 1
(Homo
sapiens;
Mus
musculus) 		5 / 12 LEU A 470
ASN A 469
LEU A 467
ALA A 388
LEU A 392
 None
 1.18A 1gs4A-6fuzA:
undetectable		 1gs4A-6fuzA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_B_HSMB402_1
(NITROPHORIN 1)		 6fuz KINESIN LIGHT CHAIN
1,KINESIN LIGHT
CHAIN
1,C-JUN-AMINO-TERMIN
AL
KINASE-INTERACTING
PROTEIN 1
(Homo
sapiens;
Mus
musculus) 		4 / 5 GLU A 487
THR A 466
LEU A 470
LEU A 467
 None
 0.85A 1u18B-6fuzA:
undetectable		 1u18B-6fuzA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_2
(PROTEASE RETROPEPSIN)		 6fuz KINESIN LIGHT CHAIN
1,KINESIN LIGHT
CHAIN
1,C-JUN-AMINO-TERMIN
AL
KINASE-INTERACTING
PROTEIN 1
(Homo
sapiens;
Mus
musculus) 		3 / 3 ARG A 410
THR A 383
VAL A 380
 None
 0.94A 2q64A-6fuzA:
undetectable		 2q64A-6fuzA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 6fuz KINESIN LIGHT CHAIN
1,KINESIN LIGHT
CHAIN
1,C-JUN-AMINO-TERMIN
AL
KINASE-INTERACTING
PROTEIN 1
(Homo
sapiens;
Mus
musculus) 		3 / 3 ARG A 410
THR A 383
VAL A 380
 None
 0.99A 2qakA-6fuzA:
undetectable		 2qakA-6fuzA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 6fuz KINESIN LIGHT CHAIN
1,KINESIN LIGHT
CHAIN
1,C-JUN-AMINO-TERMIN
AL
KINASE-INTERACTING
PROTEIN 1
(Homo
sapiens;
Mus
musculus) 		4 / 7 GLY A 308
GLY A 311
GLU A 711
ALA A 316
 None
 0.87A 3fpjB-6fuzA:
undetectable		 3fpjB-6fuzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_C_PM6C1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 6fuz KINESIN LIGHT CHAIN
1,KINESIN LIGHT
CHAIN
1,C-JUN-AMINO-TERMIN
AL
KINASE-INTERACTING
PROTEIN 1
(Homo
sapiens;
Mus
musculus) 		4 / 6 GLU A 434
ARG A 475
ALA A 482
ALA A 483
 None
 1.22A 3ns1C-6fuzA:
undetectable		 3ns1C-6fuzA:
8.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_A_IL2A901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 6fuz KINESIN LIGHT CHAIN
1,KINESIN LIGHT
CHAIN
1,C-JUN-AMINO-TERMIN
AL
KINASE-INTERACTING
PROTEIN 1
NANOBODY
(Homo
sapiens;
Lama;
Mus
musculus) 		5 / 12 PHE N  27
THR N  53
ILE N  51
LEU A 366
VAL A 380
 None
 0.90A 3sp9A-6fuzN:
undetectable		 3sp9A-6fuzN:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_B_IL2B901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 6fuz KINESIN LIGHT CHAIN
1,KINESIN LIGHT
CHAIN
1,C-JUN-AMINO-TERMIN
AL
KINASE-INTERACTING
PROTEIN 1
NANOBODY
(Homo
sapiens;
Lama;
Mus
musculus) 		5 / 12 PHE N  27
THR N  53
ILE N  51
LEU A 366
VAL A 380
 None
 0.87A 3sp9B-6fuzN:
undetectable		 3sp9B-6fuzN:
12.37