SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fv4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ALA A 173
ALA A 170
LEU A 177
ALA A 175
HIS A 188
 None
None
None
None
CD  A 403 ( 3.6A)
 0.96A 1fm6U-6fv4A:
undetectable		 1fm6U-6fv4A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FWE_C_HAEC989_1
(UREASE)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		5 / 6 HIS A  56
HIS A  58
HIS A 134
HIS A 188
HIS A 209
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.2A)
16G  A 402 (-4.0A)
CD  A 403 ( 3.6A)
CD  A 403 ( 3.7A)
 1.11A 1fweC-6fv4A:
19.8		 1fweC-6fv4A:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ITU_A_CILA451_1
(RENAL DIPEPTIDASE)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLU A 122
HIS A 134
HIS A 188
HIS A 209
ASN A 212
 CD  A 403 (-2.4A)
16G  A 402 (-4.0A)
CD  A 403 ( 3.6A)
CD  A 403 ( 3.7A)
16G  A 402 (-3.6A)
 1.17A 1ituA-6fv4A:
14.4		 1ituA-6fv4A:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_1
(MINERALOCORTICOID
RECEPTOR)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A 126
LEU A 138
ALA A  95
LEU A 284
THR A 162
 None
 1.18A 1ya3A-6fv4A:
undetectable		 1ya3A-6fv4A:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_E_H4BE1004_1
(HYPOTHETICAL PROTEIN
PH0634)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		5 / 11 HIS A 188
HIS A 134
THR A 208
GLU A 237
GLU A 122
 CD  A 403 ( 3.6A)
16G  A 402 (-4.0A)
None
None
CD  A 403 (-2.4A)
 1.47A 2dttD-6fv4A:
undetectable
2dttE-6fv4A:
undetectable		 2dttD-6fv4A:
17.54
2dttE-6fv4A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLN A 103
LEU A  57
ASP A 117
VAL A 111
ALA A  68
 None
 1.43A 2g70A-6fv4A:
undetectable		 2g70A-6fv4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACTB601_0
(ACETYLCHOLINESTERASE)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		4 / 7 GLY A  63
GLY A  62
ALA A 270
HIS A  80
 None
 0.66A 2ha4B-6fv4A:
undetectable		 2ha4B-6fv4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A 126
LEU A 138
ALA A  95
LEU A 284
THR A 162
 None
 1.21A 2oaxB-6fv4A:
undetectable		 2oaxB-6fv4A:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q9R_A_BEZA203_0
(PROTEIN OF UNKNOWN
FUNCTION)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		5 / 5 LEU A 171
GLY A 169
PRO A 142
ILE A 163
ILE A 174
 None
 1.43A 2q9rA-6fv4A:
undetectable		 2q9rA-6fv4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_B_SALB1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 THR A 162
GLY A 123
HIS A  58
THR A 208
HIS A 209
 None
None
ZN  A 401 ( 3.2A)
None
CD  A 403 ( 3.7A)
 1.12A 2y7wB-6fv4A:
undetectable		 2y7wB-6fv4A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_B_CRNB304_1
(CREATININE
AMIDOHYDROLASE)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		5 / 7 GLU A 122
HIS A 120
HIS A 188
HIS A  56
GLU A 237
 CD  A 403 (-2.4A)
None
CD  A 403 ( 3.6A)
ZN  A 401 ( 3.3A)
None
 1.20A 3a6jB-6fv4A:
undetectable		 3a6jB-6fv4A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_C_CRNC305_1
(CREATININE
AMIDOHYDROLASE)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		5 / 8 GLU A 122
HIS A 120
HIS A 188
HIS A  56
GLU A 237
 CD  A 403 (-2.4A)
None
CD  A 403 ( 3.6A)
ZN  A 401 ( 3.3A)
None
 1.20A 3a6jC-6fv4A:
undetectable		 3a6jC-6fv4A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_E_CRNE306_1
(CREATININE
AMIDOHYDROLASE)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		5 / 8 GLU A 122
HIS A 120
HIS A 188
HIS A  56
GLU A 237
 CD  A 403 (-2.4A)
None
CD  A 403 ( 3.6A)
ZN  A 401 ( 3.3A)
None
 1.20A 3a6jE-6fv4A:
undetectable		 3a6jE-6fv4A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_A_ADNA438_2
(ADENOSYLHOMOCYSTEINA
SE)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		4 / 4 GLN A 195
THR A 196
THR A 162
HIS A 188
 None
None
None
CD  A 403 ( 3.6A)
 1.49A 3g1uA-6fv4A:
undetectable		 3g1uA-6fv4A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_2
(ADENOSYLHOMOCYSTEINA
SE)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		4 / 5 GLN A 195
THR A 196
THR A 162
HIS A 188
 None
None
None
CD  A 403 ( 3.6A)
 1.47A 3g1uC-6fv4A:
2.6		 3g1uC-6fv4A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_2
(ADENOSYLHOMOCYSTEINA
SE)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		4 / 5 GLN A 195
THR A 196
THR A 162
HIS A 188
 None
None
None
CD  A 403 ( 3.6A)
 1.46A 3glqB-6fv4A:
2.7		 3glqB-6fv4A:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_B_ADNB438_1
(ADENOSYLHOMOCYSTEINA
SE)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 HIS A 188
THR A 162
THR A 208
LEU A 126
GLY A 123
 CD  A 403 ( 3.6A)
None
None
None
None
 1.40A 3h9uB-6fv4A:
2.7		 3h9uB-6fv4A:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 HIS A 188
THR A 162
THR A 208
LEU A 126
GLY A 123
 CD  A 403 ( 3.6A)
None
None
None
None
 1.41A 3h9uC-6fv4A:
2.8		 3h9uC-6fv4A:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 LEU A  57
THR A 307
THR A 266
LEU A  79
GLY A 273
 None
 1.47A 3h9uC-6fv4A:
2.8		 3h9uC-6fv4A:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 HIS A 188
THR A 162
THR A 208
LEU A 126
GLY A 123
 CD  A 403 ( 3.6A)
None
None
None
None
 1.41A 3h9uD-6fv4A:
undetectable		 3h9uD-6fv4A:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 LEU A  57
THR A 307
THR A 266
LEU A  79
GLY A 273
 None
 1.47A 3h9uD-6fv4A:
undetectable		 3h9uD-6fv4A:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGX_A_SALA102_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		4 / 7 VAL A 240
ILE A 253
TYR A 250
ILE A 249
 None
 0.68A 3hgxA-6fv4A:
undetectable		 3hgxA-6fv4A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_2
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		3 / 3 CYH A 319
PRO A 259
ASP A 325
 None
 0.86A 3hlwB-6fv4A:
undetectable		 3hlwB-6fv4A:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_C_BEZC264_0
(ECHA1_1)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		4 / 5 ALA A 213
GLU A 122
ALA A 133
MET A 139
 16G  A 402 (-4.6A)
CD  A 403 (-2.4A)
16G  A 402 (-3.8A)
None
 1.17A 3r9tC-6fv4A:
undetectable		 3r9tC-6fv4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_C_ACTC4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		4 / 4 GLY A  33
GLY A  18
THR A   4
LEU A   2
 None
 0.77A 3si7C-6fv4A:
undetectable
3si7D-6fv4A:
undetectable		 3si7C-6fv4A:
undetectable
3si7D-6fv4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_B_HAEB1270_1
(COLLAGENASE 3)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		4 / 5 LEU A 281
HIS A 209
GLU A 122
HIS A 188
 None
CD  A 403 ( 3.7A)
CD  A 403 (-2.4A)
CD  A 403 ( 3.6A)
 1.23A 4a7bB-6fv4A:
undetectable		 4a7bB-6fv4A:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVR_A_SALA203_1
(3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		4 / 7 HIS A 209
GLU A 122
HIS A  56
VAL A  93
 CD  A 403 ( 3.7A)
CD  A 403 (-2.4A)
ZN  A 401 ( 3.3A)
None
 0.93A 4hvrA-6fv4A:
undetectable		 4hvrA-6fv4A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		4 / 7 LEU A 357
THR A 378
ALA A 368
THR A 367
 None
 0.92A 4pwjB-6fv4A:
undetectable		 4pwjB-6fv4A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7L_A_SHHA709_1
(LEUKOTRIENE A-4
HYDROLASE)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ALA A 164
HIS A  56
GLU A 237
HIS A 209
GLU A 122
 None
ZN  A 401 ( 3.3A)
None
CD  A 403 ( 3.7A)
CD  A 403 (-2.4A)
 0.97A 4r7lA-6fv4A:
undetectable		 4r7lA-6fv4A:
9.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBP_C_HAEC800_1
(PROTEIN (UREASE
(CHAIN C)))		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		5 / 6 HIS A  56
HIS A  58
HIS A 134
HIS A 188
HIS A 209
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.2A)
16G  A 402 (-4.0A)
CD  A 403 ( 3.6A)
CD  A 403 ( 3.7A)
 1.12A 4ubpC-6fv4A:
19.7		 4ubpC-6fv4A:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XR4_B_AG2B511_1
(HOMOSPERMIDINE
SYNTHASE)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		3 / 3 VAL A 358
PHE A 312
ARG A 313
 None
 0.98A 4xr4B-6fv4A:
2.4		 4xr4B-6fv4A:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_A_STRA604_1
(CYTOCHROME P450
21-HYDROXYLASE)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 VAL A 104
LEU A 107
ILE A 119
GLY A 118
LEU A  57
 None
 1.07A 4y8wA-6fv4A:
undetectable		 4y8wA-6fv4A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_B_STRB603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 VAL A 104
LEU A 107
ILE A 119
GLY A 118
LEU A  57
 None
 1.09A 4y8wB-6fv4A:
undetectable		 4y8wB-6fv4A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		4 / 7 VAL A 104
ALA A 108
GLY A 156
VAL A 158
 None
 0.88A 5fpdA-6fv4A:
undetectable		 5fpdA-6fv4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_0
(METHYLTRANSFERASE)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A  79
ALA A  78
VAL A  77
PHE A  65
ALA A 270
 None
 1.15A 5n5dB-6fv4A:
undetectable		 5n5dB-6fv4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		5 / 9 GLY A 156
VAL A 150
ILE A 119
GLY A 118
ILE A 163
 None
 0.96A 5vkqC-6fv4A:
2.2
5vkqD-6fv4A:
2.2		 5vkqC-6fv4A:
undetectable
5vkqD-6fv4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 VAL A  53
SER A  85
THR A  86
LEU A 262
VAL A 311
 None
 1.11A 6a93B-6fv4A:
undetectable		 6a93B-6fv4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 HIS A 209
ILE A 239
ALA A 267
HIS A  56
HIS A 120
 CD  A 403 ( 3.7A)
None
CL  A 405 (-3.5A)
ZN  A 401 ( 3.3A)
None
 1.05A 6n91A-6fv4A:
14.9		 6n91A-6fv4A:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ILE A 239
SER A 304
ALA A 267
HIS A  56
HIS A 120
 None
None
CL  A 405 (-3.5A)
ZN  A 401 ( 3.3A)
None
 1.33A 6n91A-6fv4A:
14.9		 6n91A-6fv4A:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 6fv4 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 HIS A 209
ILE A 239
ALA A 267
HIS A  56
HIS A 120
 CD  A 403 ( 3.7A)
None
CL  A 405 (-3.5A)
ZN  A 401 ( 3.3A)
None
 1.05A 6n91B-6fv4A:
14.9		 6n91B-6fv4A:
19.54