SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fv5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H9Z_A_RWFA3001_1
(SERUM ALBUMIN)		 6fv5 QUEUINE
TRNA-RIBOSYLTRANSFER
ASE ACCESSORY
SUBUNIT 2
(Mus
musculus) 		5 / 11 ALA A 135
LEU A  74
LEU A 136
LEU A  62
ALA A  68
 None
 1.15A 1h9zA-6fv5A:
undetectable		 1h9zA-6fv5A:
7.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_B_CCSB417_0
(ESTROGEN RECEPTOR)		 6fv5 QUEUINE
TRNA-RIBOSYLTRANSFER
ASE ACCESSORY
SUBUNIT 2
(Mus
musculus) 		4 / 6 PRO A 276
PHE A 275
GLN A 278
VAL A 254
 None
 1.25A 1l2iB-6fv5A:
undetectable		 1l2iB-6fv5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LBD_A_REAA500_1
(RETINOIC ACID
RECEPTOR GAMMA)		 6fv5 QUEUINE
TRNA-RIBOSYLTRANSFER
ASE ACCESSORY
SUBUNIT 2
(Mus
musculus) 		5 / 12 LEU A 218
ILE A 193
ARG A 202
GLY A 215
LEU A 175
 None
 1.26A 2lbdA-6fv5A:
undetectable		 2lbdA-6fv5A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 6fv5 QUEUINE
TRNA-RIBOSYLTRANSFER
ASE ACCESSORY
SUBUNIT 2
(Mus
musculus) 		4 / 5 SER A 163
GLY A 195
ASP A 225
ASP A 220
 None
 1.06A 2oxtB-6fv5A:
undetectable		 2oxtB-6fv5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 6fv5 QUEUINE
TRNA-RIBOSYLTRANSFER
ASE ACCESSORY
SUBUNIT 2
(Mus
musculus) 		3 / 3 VAL A 164
ASP A 165
GLU A 201
 None
 0.59A 2qeuA-6fv5A:
undetectable		 2qeuA-6fv5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_C_ACTC141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 6fv5 QUEUINE
TRNA-RIBOSYLTRANSFER
ASE ACCESSORY
SUBUNIT 2
(Mus
musculus) 		3 / 3 VAL A 164
ASP A 165
GLU A 201
 None
 0.58A 2qeuC-6fv5A:
undetectable		 2qeuC-6fv5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RK8_B_PPFB3969_1
(PHOSPHOENOLPYRUVATE
CARBOXYKINASE,
CYTOSOLIC [GTP])		 6fv5 QUEUINE
TRNA-RIBOSYLTRANSFER
ASE ACCESSORY
SUBUNIT 2
(Mus
musculus) 		4 / 7 ARG A 232
SER A 150
ASP A 220
ARG A 202
 None
 1.37A 2rk8B-6fv5A:
undetectable		 2rk8B-6fv5A:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W1B_A_DXCA2034_0
(ACRIFLAVIN
RESISTANCE PROTEIN B)		 6fv5 QUEUINE
TRNA-RIBOSYLTRANSFER
ASE ACCESSORY
SUBUNIT 2
(Mus
musculus) 		3 / 3 PHE A 141
SER A 181
LEU A 177
 None
 0.53A 2w1bA-6fv5A:
undetectable		 2w1bA-6fv5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_D_SALD1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 6fv5 QUEUINE
TRNA-RIBOSYLTRANSFER
ASE ACCESSORY
SUBUNIT 2
(Mus
musculus) 		5 / 12 ILE A  30
GLY A  32
PHE A 271
LEU A 398
ILE A 264
 None
 1.14A 2y7kD-6fv5A:
undetectable		 2y7kD-6fv5A:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)		 6fv5 QUEUINE
TRNA-RIBOSYLTRANSFER
ASE ACCESSORY
SUBUNIT 2
(Mus
musculus) 		5 / 10 GLY A 283
GLU A 332
LEU A 335
LEU A 368
ILE A 364
 None
 1.31A 3kvrA-6fv5A:
undetectable		 3kvrA-6fv5A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 6fv5 QUEUINE
TRNA-RIBOSYLTRANSFER
ASE ACCESSORY
SUBUNIT 2
(Mus
musculus) 		5 / 10 GLY A 283
GLU A 332
LEU A 335
LEU A 368
ILE A 364
 None
 1.29A 3kvrB-6fv5A:
undetectable		 3kvrB-6fv5A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_B_VORB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 6fv5 QUEUINE
TRNA-RIBOSYLTRANSFER
ASE ACCESSORY
SUBUNIT 2
(Mus
musculus) 		5 / 11 LEU A 219
PHE A 222
ILE A 193
ALA A 241
ALA A 206
 None
 1.08A 3mdtB-6fv5A:
undetectable		 3mdtB-6fv5A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_A_URFA400_1
(URIDINE
PHOSPHORYLASE 1)		 6fv5 QUEUINE
TRNA-RIBOSYLTRANSFER
ASE ACCESSORY
SUBUNIT 2
(Mus
musculus) 		5 / 9 GLY A 283
GLU A 332
LEU A 335
LEU A 368
ILE A 364
 None
 1.26A 3nbqA-6fv5A:
undetectable		 3nbqA-6fv5A:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)		 6fv5 QUEUINE
TRNA-RIBOSYLTRANSFER
ASE ACCESSORY
SUBUNIT 2
(Mus
musculus) 		4 / 8 GLY A 283
LEU A 335
LEU A 368
ILE A 364
 None
 0.87A 3nbqB-6fv5A:
undetectable		 3nbqB-6fv5A:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)		 6fv5 QUEUINE
TRNA-RIBOSYLTRANSFER
ASE ACCESSORY
SUBUNIT 2
(Mus
musculus) 		4 / 8 GLY A 376
LEU A 378
LEU A 379
ILE A 364
 None
 0.82A 3nbqB-6fv5A:
undetectable		 3nbqB-6fv5A:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_C_URFC400_1
(URIDINE
PHOSPHORYLASE 1)		 6fv5 QUEUINE
TRNA-RIBOSYLTRANSFER
ASE ACCESSORY
SUBUNIT 2
(Mus
musculus) 		4 / 8 GLY A 283
LEU A 335
LEU A 368
ILE A 364
 None
 0.78A 3nbqC-6fv5A:
undetectable		 3nbqC-6fv5A:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_C_URFC400_1
(URIDINE
PHOSPHORYLASE 1)		 6fv5 QUEUINE
TRNA-RIBOSYLTRANSFER
ASE ACCESSORY
SUBUNIT 2
(Mus
musculus) 		4 / 8 GLY A 376
LEU A 378
LEU A 379
ILE A 364
 None
 0.86A 3nbqC-6fv5A:
undetectable		 3nbqC-6fv5A:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA502_0
(RNA POLYMERASE
3D-POL)		 6fv5 QUEUINE
TRNA-RIBOSYLTRANSFER
ASE ACCESSORY
SUBUNIT 2
(Mus
musculus) 		3 / 3 ARG A 161
LYS A 162
LYS A 158
 None
 1.40A 4k50A-6fv5A:
undetectable		 4k50A-6fv5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE502_0
(RNA POLYMERASE
3D-POL)		 6fv5 QUEUINE
TRNA-RIBOSYLTRANSFER
ASE ACCESSORY
SUBUNIT 2
(Mus
musculus) 		3 / 3 ARG A 161
LYS A 162
LYS A 158
 None
 1.42A 4k50E-6fv5A:
undetectable		 4k50E-6fv5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7I_A_STIA1001_2
(MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR)		 6fv5 QUEUINE
TRNA-RIBOSYLTRANSFER
ASE ACCESSORY
SUBUNIT 2
(Mus
musculus) 		4 / 5 LEU A 378
VAL A 348
TYR A 354
ARG A 256
 None
 1.09A 4r7iA-6fv5A:
undetectable		 4r7iA-6fv5A:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 6fv5 QUEUINE
TRNA-RIBOSYLTRANSFER
ASE ACCESSORY
SUBUNIT 2
(Mus
musculus) 		5 / 12 GLN A 133
ILE A 189
VAL A 188
GLY A 191
HIS A  97
 None
 0.97A 5ergB-6fv5A:
undetectable		 5ergB-6fv5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_2
(CDL2.2)		 6fv5 QUEUINE
TRNA-RIBOSYLTRANSFER
ASE ACCESSORY
SUBUNIT 2
(Mus
musculus) 		5 / 12 LEU A  64
PHE A 129
LEU A 171
LEU A  96
ILE A 193
 None
 1.17A 5ienB-6fv5A:
undetectable		 5ienB-6fv5A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA612_1
(SERUM ALBUMIN)		 6fv5 QUEUINE
TRNA-RIBOSYLTRANSFER
ASE ACCESSORY
SUBUNIT 2
(Mus
musculus) 		5 / 12 LYS A 128
LEU A  74
LEU A 136
LEU A  62
ALA A  68
 None
 1.07A 5v0vA-6fv5A:
undetectable		 5v0vA-6fv5A:
9.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_D_ACTD404_0
(L-LYSINE
3-HYDROXYLASE)		 6fv5 QUEUINE
TRNA-RIBOSYLTRANSFER
ASE ACCESSORY
SUBUNIT 2
(Mus
musculus) 		4 / 6 GLN A 137
GLU A 134
HIS A  71
ALA A  75
 None
 1.24A 6f6jC-6fv5A:
undetectable
6f6jD-6fv5A:
undetectable		 6f6jC-6fv5A:
undetectable
6f6jD-6fv5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GQI_A_ACTA604_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 6fv5 QUEUINE
TRNA-RIBOSYLTRANSFER
ASE ACCESSORY
SUBUNIT 2
(Mus
musculus) 		4 / 6 PRO A  57
ILE A  53
GLY A  55
GLU A 385
 None
 1.13A 6gqiA-6fv5A:
undetectable		 6gqiA-6fv5A:
undetectable