SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fwf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		5 / 12 THR A 196
ALA A 200
ILE A 619
LEU A 621
LEU A 703
 None
None
None
HEM  A1001 (-4.8A)
None
 1.25A 1eiiA-6fwfA:
undetectable		 1eiiA-6fwfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_A_115A2_2
(HMG-COA REDUCTASE)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		4 / 8 GLU A  68
HIS A 335
ALA A 634
LEU A 638
 None
HEM  A1002 (-3.2A)
HEM  A1002 ( 3.8A)
HEM  A1002 ( 4.2A)
 1.06A 1hwiB-6fwfA:
undetectable		 1hwiB-6fwfA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		5 / 12 GLY A 547
VAL A  29
ALA A 200
SER A 199
TRP A 215
 None
 1.33A 1kiaD-6fwfA:
undetectable		 1kiaD-6fwfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		3 / 3 TRP A 215
TYR A 623
LEU A 627
 None
 0.76A 1kxhA-6fwfA:
undetectable		 1kxhA-6fwfA:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		5 / 12 GLY A 547
VAL A  29
ALA A 200
SER A 199
TRP A 215
 None
 1.33A 1nbhA-6fwfA:
undetectable		 1nbhA-6fwfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		5 / 12 GLY A 547
VAL A  29
ALA A 200
SER A 199
TRP A 215
 None
 1.33A 1nbhC-6fwfA:
undetectable		 1nbhC-6fwfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		5 / 12 GLY A 547
VAL A  29
ALA A 200
SER A 199
TRP A 215
 None
 1.33A 1nbhD-6fwfA:
undetectable		 1nbhD-6fwfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		4 / 8 ILE A  21
LEU A 540
GLY A 538
PHE A 559
 None
 0.85A 1rtsA-6fwfA:
undetectable		 1rtsA-6fwfA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V3E_A_ZMRA1200_1
(HEMAGGLUTININ-NEURAM
INIDASE GLYCOPROTEIN)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		5 / 10 THR A  99
GLU A  91
TYR A 127
PHE A 194
GLU A 126
 None
 1.47A 1v3eA-6fwfA:
undetectable		 1v3eA-6fwfA:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V3E_B_ZMRB2200_1
(HEMAGGLUTININ-NEURAM
INIDASE GLYCOPROTEIN)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		5 / 10 THR A  99
GLU A  91
TYR A 127
PHE A 194
GLU A 126
 None
 1.44A 1v3eB-6fwfA:
undetectable		 1v3eB-6fwfA:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		4 / 8 LEU A 567
HIS A 490
GLU A 563
HIS A 541
 HEM  A1001 (-4.8A)
FE  A1004 ( 2.4A)
HEM  A1001 ( 4.7A)
FE  A1004 (-3.0A)
 0.91A 2bnnA-6fwfA:
undetectable
2bnnB-6fwfA:
undetectable		 2bnnA-6fwfA:
18.69
2bnnB-6fwfA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_B_GBNB914_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		5 / 10 PHE A 531
TYR A 642
GLY A 612
GLY A 607
ALA A 637
 None
HEM  A1001 (-3.9A)
HEM  A1001 (-3.2A)
None
HEM  A1001 (-3.8A)
 1.11A 2ej3B-6fwfA:
undetectable		 2ej3B-6fwfA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_B_IBPB1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		4 / 8 GLY A 416
GLY A 409
GLN A  62
THR A  63
 None
 0.72A 2wd9B-6fwfA:
undetectable		 2wd9B-6fwfA:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		4 / 5 PHE A 500
PHE A 347
LEU A 645
PHE A 597
 None
 1.36A 2y69C-6fwfA:
2.6
2y69J-6fwfA:
undetectable		 2y69C-6fwfA:
undetectable
2y69J-6fwfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_P_CHDP1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		4 / 5 PHE A 500
PHE A 347
LEU A 645
PHE A 597
 None
 1.33A 2y69P-6fwfA:
2.6
2y69W-6fwfA:
undetectable		 2y69P-6fwfA:
undetectable
2y69W-6fwfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		3 / 3 GLU A 218
ASP A  86
TYR A 155
 None
 0.85A 2yvlB-6fwfA:
undetectable		 2yvlB-6fwfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		4 / 5 PHE A 500
PHE A 347
LEU A 645
PHE A 597
 None
 1.34A 3abmP-6fwfA:
2.6
3abmW-6fwfA:
undetectable		 3abmP-6fwfA:
undetectable
3abmW-6fwfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_2
(GLUCOSYLTRANSFERASE-
SI)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		3 / 3 LEU A 627
TRP A 704
TYR A 623
 None
 0.97A 3aicA-6fwfA:
undetectable		 3aicA-6fwfA:
6.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_2
(GLUCOSYLTRANSFERASE-
SI)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		3 / 3 LEU A 627
TRP A 704
TYR A 623
 None
 1.01A 3aicB-6fwfA:
undetectable		 3aicB-6fwfA:
6.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_2
(GLUCOSYLTRANSFERASE-
SI)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		3 / 3 LEU A 627
TRP A 704
TYR A 623
 None
 0.99A 3aicE-6fwfA:
undetectable		 3aicE-6fwfA:
6.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_2
(GLUCOSYLTRANSFERASE-
SI)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		3 / 3 LEU A 627
TRP A 704
TYR A 623
 None
 0.96A 3aicF-6fwfA:
undetectable		 3aicF-6fwfA:
6.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_2
(GLUCOSYLTRANSFERASE-
SI)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		3 / 3 LEU A 627
TRP A 704
TYR A 623
 None
 0.99A 3aicH-6fwfA:
undetectable		 3aicH-6fwfA:
6.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D9L_A_ACTA501_0
(CTD-PEPTIDE
RNA-BINDING PROTEIN
16)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		4 / 5 PRO A 618
ILE A 619
PRO A 225
TYR A 230
 None
 0.93A 3d9lA-6fwfA:
undetectable
3d9lY-6fwfA:
undetectable		 3d9lA-6fwfA:
undetectable
3d9lY-6fwfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		4 / 8 TYR A 104
SER A  93
LEU A  96
ASP A  97
 None
 0.92A 3lsfH-6fwfA:
undetectable		 3lsfH-6fwfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_C_OBNC1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		5 / 11 LEU A 431
VAL A 460
ALA A 457
PHE A 455
PHE A 507
 None
 1.26A 3n23C-6fwfA:
undetectable		 3n23C-6fwfA:
7.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S38_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		3 / 3 HIS A 490
HIS A 541
HIS A 542
 FE  A1004 ( 2.4A)
FE  A1004 (-3.0A)
FE  A1004 ( 3.0A)
 0.76A 3s38A-6fwfA:
0.0		 3s38A-6fwfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3C_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		3 / 3 HIS A 490
HIS A 541
HIS A 542
 FE  A1004 ( 2.4A)
FE  A1004 (-3.0A)
FE  A1004 ( 3.0A)
 0.79A 3s3cA-6fwfA:
17.0		 3s3cA-6fwfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		4 / 5 ASP A 315
GLU A 316
GLY A 319
ASP A 324
 None
 1.16A 3w9tD-6fwfA:
undetectable		 3w9tD-6fwfA:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3Q_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		4 / 7 LEU A 352
LYS A 276
LEU A 374
TYR A 283
 None
 1.16A 4b3qA-6fwfA:
undetectable		 4b3qA-6fwfA:
10.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_0U9A601_1
(CHOLESTEROL
24-HYDROXYLASE)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		5 / 12 PHE A 455
ALA A 646
TRP A 430
ALA A 350
THR A 349
 None
 1.16A 4fiaA-6fwfA:
undetectable		 4fiaA-6fwfA:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_198A602_1
(CHOLESTEROL
24-HYDROXYLASE)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		5 / 12 PHE A 455
ALA A 646
TRP A 430
ALA A 350
THR A 349
 None
 1.16A 4fiaA-6fwfA:
undetectable		 4fiaA-6fwfA:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQI_A_NIOA403_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		5 / 9 GLY A  76
GLY A 409
GLU A 411
ARG A 332
GLY A  66
 CA  A1003 ( 3.8A)
None
CA  A1003 (-2.0A)
HEM  A1002 (-3.5A)
None
 1.34A 4kqiA-6fwfA:
undetectable		 4kqiA-6fwfA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLF_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		5 / 12 VAL A 381
PHE A 403
THR A  63
TRP A  61
GLY A  65
 None
 1.06A 4olfA-6fwfA:
undetectable		 4olfA-6fwfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAH_A_LNRA600_1
(PHENYLALANINE
HYDROXYLASE)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		4 / 6 LEU A 645
PHE A 505
HIS A 577
GLU A 573
 None
 1.14A 4pahA-6fwfA:
undetectable		 4pahA-6fwfA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_A_ML1A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		4 / 8 TYR A 312
PHE A 311
GLY A 299
ILE A 732
 None
None
HEM  A1002 (-3.6A)
HEM  A1002 (-4.5A)
 0.87A 4qoiA-6fwfA:
undetectable
4qoiB-6fwfA:
undetectable		 4qoiA-6fwfA:
23.96
4qoiB-6fwfA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		4 / 5 LEU A  92
SER A  93
ASP A  86
ASP A 163
 None
 1.20A 4qtuD-6fwfA:
undetectable		 4qtuD-6fwfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		5 / 9 ALA A 501
THR A 502
ALA A 504
VAL A 493
GLY A 495
 None
 1.24A 4qvnY-6fwfA:
undetectable
4qvnZ-6fwfA:
undetectable		 4qvnY-6fwfA:
18.87
4qvnZ-6fwfA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		5 / 10 HIS A 490
VAL A 493
VAL A 489
LEU A 638
ALA A 637
 FE  A1004 ( 2.4A)
None
None
HEM  A1002 ( 4.2A)
HEM  A1001 (-3.8A)
 1.46A 4yhaB-6fwfA:
undetectable		 4yhaB-6fwfA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		4 / 8 ASN A 229
PRO A 225
PHE A 622
SER A 620
 None
 1.14A 5amiB-6fwfA:
undetectable		 5amiB-6fwfA:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		4 / 6 PHE A 193
SER A 138
VAL A  40
ASP A  53
 None
 1.29A 5hesA-6fwfA:
undetectable		 5hesA-6fwfA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_E_EDTE301_0
(BETA-2-MICROGLOBULIN
TCRBETA CHAIN)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		4 / 8 THR A 210
THR A 212
PRO A 219
ILE A 221
 None
 1.13A 5jhdE-6fwfA:
undetectable
5jhdG-6fwfA:
undetectable		 5jhdE-6fwfA:
undetectable
5jhdG-6fwfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		5 / 12 HIS A 577
ALA A 601
THR A 502
GLY A 648
LEU A 645
 None
 1.29A 5m54E-6fwfA:
undetectable		 5m54E-6fwfA:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MXB_A_ML1A222_1
(CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		6 / 10 THR A 349
LEU A 354
PHE A 353
GLY A 648
ALA A 646
PHE A 649
 None
 1.11A 5mxbA-6fwfA:
undetectable		 5mxbA-6fwfA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		4 / 7 ILE A  21
LEU A 540
GLY A 538
PHE A 559
 None
 0.85A 5x5qC-6fwfA:
undetectable		 5x5qC-6fwfA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		4 / 8 ILE A  21
LEU A 540
GLY A 538
PHE A 559
 None
 0.85A 5x5qD-6fwfA:
undetectable		 5x5qD-6fwfA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_F_D16F402_1
(THYMIDYLATE SYNTHASE)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		4 / 8 ILE A  21
LEU A 540
GLY A 538
PHE A 559
 None
 0.84A 5x5qF-6fwfA:
undetectable		 5x5qF-6fwfA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_2
(PROTEIN CYP51)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		4 / 7 VAL A 488
LEU A 433
PHE A 496
LEU A 348
 None
 1.20A 6aycA-6fwfA:
0.4		 6aycA-6fwfA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		3 / 3 HIS A 490
HIS A 541
HIS A 542
 FE  A1004 ( 2.4A)
FE  A1004 (-3.0A)
FE  A1004 ( 3.0A)
 0.49A 6giqa-6fwfA:
17.3		 6giqa-6fwfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_1
(-)		 6fwf NITRIC-OXIDE
REDUCTASE
(Neisseria
meningitidis) 		5 / 12 THR A 301
GLY A 298
LEU A 297
VAL A 293
GLY A  70
 HEM  A1002 (-4.4A)
HEM  A1002 (-3.4A)
None
None
None
 1.17A 6gngA-6fwfA:
undetectable		 6gngA-6fwfA:
9.15