SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fwv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 6fwv -
(-) 		5 / 11 THR A 238
THR A 237
ALA A  38
ARG A 243
GLY A  57
 None
 1.13A 2f162-6fwvA:
undetectable		 2f162-6fwvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 6fwv -
(-) 		5 / 11 THR A 238
THR A 237
ALA A  38
ARG A 243
GLY A  57
 None
 1.12A 2f16N-6fwvA:
undetectable		 2f16N-6fwvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		 6fwv -
(-) 		4 / 6 TYR A  89
ALA A  90
LEU A  93
ALA A 109
 None
None
None
ZN  A 601 ( 4.4A)
 0.80A 3b6hA-6fwvA:
undetectable		 3b6hA-6fwvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FSU_E_C2FE995_0
(5,10-METHYLENETETRAH
YDROFOLATE REDUCTASE)		 6fwv -
(-) 		5 / 11 GLN A  73
LEU A  67
THR A 238
LEU A 121
ARG A 120
 None
 1.44A 3fsuE-6fwvA:
undetectable		 3fsuE-6fwvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 6fwv -
(-) 		5 / 11 THR A 238
THR A 237
ALA A  38
ARG A 243
GLY A  57
 None
 1.12A 3mg0N-6fwvA:
undetectable		 3mg0N-6fwvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA301_1
(CHITOSANASE)		 6fwv -
(-) 		3 / 3 TYR A  71
GLY A  75
PRO A  76
 None
 0.51A 4qwpA-6fwvA:
undetectable		 4qwpA-6fwvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA305_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 6fwv -
(-) 		4 / 6 LEU A 300
LEU A 262
GLU A 299
ILE A 264
 None
 0.97A 4ww7A-6fwvA:
1.8		 4ww7A-6fwvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Q1S_A_AWYA1103_0
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 6fwv -
(-) 		4 / 6 VAL A 281
LYS A 311
ILE A 264
LYS A 326
 None
 1.13A 5q1sA-6fwvA:
undetectable		 5q1sA-6fwvA:
undetectable