SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fxn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HW2_A_RFPA1200_1
(RIFAMPIN ADP-RIBOSYL
TRANSFERASE)		 6fxn BELIMUMAB HEAVY
CHAIN
(Homo
sapiens) 		5 / 12 ALA D  72
GLY D  77
ASN D  32
GLY D 114
LEU D   4
 None
 1.09A 2hw2A-6fxnD:
undetectable		 2hw2A-6fxnD:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HDL_A_DXCA75_0
(PPCA)		 6fxn BELIMUMAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 8 ILE D  70
ILE D  52
PHE D  29
GLY D  77
 None
 0.97A 4hdlA-6fxnD:
undetectable		 4hdlA-6fxnD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 6fxn BELIMUMAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 ALA D  92
THR D  91
VAL D 119
GLU D  89
 None
 0.74A 5ecmD-6fxnD:
undetectable		 5ecmD-6fxnD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 6fxn BELIMUMAB HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 ALA D  92
THR D  91
VAL D 119
GLU D  89
 None
 0.80A 5ecoD-6fxnD:
undetectable		 5ecoD-6fxnD:
undetectable