SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fyd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		4 / 6 ASN A 375
ALA A 431
GLY A 433
TYR A 432
 None
 1.05A 1c8lA-6fydA:
undetectable		 1c8lA-6fydA:
8.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		4 / 6 ASN A 375
ALA A 431
GLY A 433
TYR A 432
 None
 1.08A 1gfzA-6fydA:
undetectable		 1gfzA-6fydA:
8.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_4
(HIV-1 PROTEASE)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		4 / 4 GLY A 149
ASP A 162
GLY A 360
THR A 245
 FAD  A 600 (-3.6A)
None
None
None
 1.08A 1hxbB-6fydA:
undetectable		 1hxbB-6fydA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IOL_A_ESTA400_1
(ESTROGENIC 17-BETA
HYDROXYSTEROID
DEHYDROGENASE)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		5 / 11 VAL A 145
GLY A 148
TYR A 416
GLY A 143
TYR A 432
 None
None
FAD  A 600 (-4.4A)
FAD  A 600 (-3.2A)
None
 1.26A 1iolA-6fydA:
undetectable		 1iolA-6fydA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHR_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		5 / 9 GLY A 360
PHE A 150
LEU A 159
ARG A 155
GLY A 158
 None
FAD  A 600 (-3.7A)
None
None
None
 1.22A 1jhrA-6fydA:
undetectable		 1jhrA-6fydA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		4 / 6 ASN A 375
ALA A 431
GLY A 433
TYR A 432
 None
 1.09A 1l5qA-6fydA:
undetectable		 1l5qA-6fydA:
6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		4 / 6 ASN A 375
ALA A 431
GLY A 433
TYR A 432
 None
 1.11A 1l5qB-6fydA:
undetectable		 1l5qB-6fydA:
6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		4 / 6 ASN A 375
ALA A 431
GLY A 433
TYR A 432
 None
 1.08A 1l7xA-6fydA:
undetectable		 1l7xA-6fydA:
6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		4 / 6 ASN A 375
ALA A 431
GLY A 433
TYR A 432
 None
 1.07A 1l7xB-6fydA:
undetectable		 1l7xB-6fydA:
6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_C_AG2C7004_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		4 / 6 ALA A 232
LEU A 332
LEU A 248
LEU A 341
 None
 0.90A 1mt1D-6fydA:
undetectable
1mt1E-6fydA:
undetectable		 1mt1D-6fydA:
16.81
1mt1E-6fydA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NHZ_A_486A800_1
(GLUCOCORTICOID
RECEPTOR)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		5 / 12 GLY A 193
VAL A 191
LEU A 159
ARG A 376
LEU A 144
 None
None
None
None
FAD  A 600 (-3.7A)
 1.36A 1nhzA-6fydA:
undetectable		 1nhzA-6fydA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		5 / 9 GLY A 404
ALA A 344
THR A 339
HIS A 411
THR A 382
 None
 1.48A 1utdD-6fydA:
undetectable
1utdE-6fydA:
1.0		 1utdD-6fydA:
undetectable
1utdE-6fydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		4 / 8 TRP A  24
PHE A  63
ALA A  46
LEU A  47
 None
 0.85A 2o01A-6fydA:
undetectable		 2o01A-6fydA:
7.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		4 / 6 PHE A 204
PHE A 206
GLY A 148
GLY A 149
 None
None
None
FAD  A 600 (-3.6A)
 0.95A 2qr2A-6fydA:
undetectable
2qr2B-6fydA:
undetectable		 2qr2A-6fydA:
18.23
2qr2B-6fydA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		4 / 5 GLY A 148
GLY A 149
PHE A 204
PHE A 206
 None
FAD  A 600 (-3.6A)
None
None
 0.98A 2qr2A-6fydA:
undetectable
2qr2B-6fydA:
undetectable		 2qr2A-6fydA:
18.23
2qr2B-6fydA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		4 / 6 GLY A 149
GLY A 195
PHE A 204
PHE A 206
 FAD  A 600 (-3.6A)
None
None
None
 0.89A 2qx6A-6fydA:
undetectable
2qx6B-6fydA:
undetectable		 2qx6A-6fydA:
18.23
2qx6B-6fydA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCD_A_RAPA138_1
(OUTER MEMBRANE
PROTEIN MIP)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		5 / 11 PHE A 453
PHE A 204
VAL A 167
ILE A 169
VAL A  58
 None
 1.33A 2vcdA-6fydA:
undetectable		 2vcdA-6fydA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		4 / 5 ASN A 375
ALA A 431
GLY A 433
TYR A 432
 None
 1.08A 3bcrA-6fydA:
undetectable		 3bcrA-6fydA:
8.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		4 / 6 ASN A 375
ALA A 431
GLY A 433
TYR A 432
 None
 1.07A 3dd1A-6fydA:
undetectable		 3dd1A-6fydA:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		4 / 6 ASN A 375
ALA A 431
GLY A 433
TYR A 432
 None
 1.06A 3dd1B-6fydA:
undetectable		 3dd1B-6fydA:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		4 / 6 ASN A 375
ALA A 431
GLY A 433
TYR A 432
 None
 1.09A 3ddsA-6fydA:
undetectable		 3ddsA-6fydA:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		4 / 6 ASN A 375
ALA A 431
GLY A 433
TYR A 432
 None
 1.08A 3ddsB-6fydA:
undetectable		 3ddsB-6fydA:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		4 / 6 ASN A 375
ALA A 431
GLY A 433
TYR A 432
 None
 1.08A 3ddwA-6fydA:
undetectable		 3ddwA-6fydA:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		4 / 6 ASN A 375
ALA A 431
GLY A 433
TYR A 432
 None
 1.07A 3ddwB-6fydA:
undetectable		 3ddwB-6fydA:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_D_486D2_1
(GLUCOCORTICOID
RECEPTOR)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		5 / 12 GLY A 193
VAL A 191
LEU A 159
ARG A 376
LEU A 144
 None
None
None
None
FAD  A 600 (-3.7A)
 1.42A 3h52D-6fydA:
undetectable		 3h52D-6fydA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_2
(HIV-1 PROTEASE)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		4 / 4 GLY A 149
ASP A 162
GLY A 360
THR A 245
 FAD  A 600 (-3.6A)
None
None
None
 1.06A 3k4vC-6fydA:
undetectable		 3k4vC-6fydA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_B_SAMB6735_0
(16S RRNA METHYLASE)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		5 / 12 GLY A 114
GLY A  75
ALA A 203
GLU A 168
THR A  54
 None
FAD  A 600 (-3.4A)
None
None
None
 1.15A 3p2kB-6fydA:
undetectable		 3p2kB-6fydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7V_A_SAMA992_0
(METHYLORNITHINE
SYNTHASE PYLB)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		5 / 12 GLY A 414
GLU A 424
ARG A 427
MET A  80
ALA A 385
 None
None
None
FAD  A 600 (-4.9A)
None
 1.14A 3t7vA-6fydA:
undetectable		 3t7vA-6fydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_B_SAMB1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		5 / 12 HIS A  83
GLY A  77
GLY A  82
HIS A 138
GLY A 114
 FAD  A 600 ( 4.7A)
FAD  A 600 (-3.5A)
None
None
None
 1.16A 4blvB-6fydA:
undetectable		 4blvB-6fydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_B_SAMB301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		5 / 12 GLY A 149
GLY A 148
GLY A 147
GLN A 309
VAL A 135
 FAD  A 600 (-3.6A)
None
None
None
FAD  A 600 (-3.3A)
 0.96A 4htfB-6fydA:
undetectable		 4htfB-6fydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_A_LURA201_1
(TRANSTHYRETIN)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		3 / 3 LYS A 300
LEU A 298
ALA A 217
 None
 0.49A 4iizA-6fydA:
undetectable		 4iizA-6fydA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA407_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		3 / 3 GLU A 393
ARG A 396
HIS A 397
 None
 0.81A 4kf9A-6fydA:
undetectable		 4kf9A-6fydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM9_A_FVXA603_1
(TRANSPORTER)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		5 / 11 VAL A  85
GLY A  39
SER A  79
GLY A  77
ASP A  87
 None
None
FAD  A 600 (-4.3A)
FAD  A 600 (-3.5A)
None
 1.27A 4mm9A-6fydA:
undetectable		 4mm9A-6fydA:
9.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		5 / 12 VAL A 145
ILE A 161
GLY A 199
VAL A  57
LEU A  94
 None
None
None
None
FAD  A 600 (-4.7A)
 1.02A 4y8wC-6fydA:
undetectable		 4y8wC-6fydA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		5 / 9 THR A 382
GLY A 404
ALA A 344
THR A 339
HIS A 411
 None
 1.47A 5eezJ-6fydA:
0.8
5eezK-6fydA:
0.8		 5eezJ-6fydA:
undetectable
5eezK-6fydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		5 / 9 THR A 382
GLY A 404
ALA A 344
THR A 339
HIS A 411
 None
 1.47A 5ef0J-6fydA:
0.8
5ef0K-6fydA:
0.9		 5ef0J-6fydA:
undetectable
5ef0K-6fydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		5 / 9 THR A 382
GLY A 404
ALA A 344
THR A 339
HIS A 411
 None
 1.47A 5ef1J-6fydA:
0.7
5ef1K-6fydA:
0.9		 5ef1J-6fydA:
undetectable
5ef1K-6fydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		5 / 9 THR A 382
GLY A 404
ALA A 344
THR A 339
HIS A 411
 None
 1.48A 5ef2J-6fydA:
0.7
5ef2K-6fydA:
0.9		 5ef2J-6fydA:
undetectable
5ef2K-6fydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		5 / 9 THR A 382
GLY A 404
ALA A 344
THR A 339
HIS A 411
 None
 1.48A 5ef3J-6fydA:
0.8
5ef3K-6fydA:
0.9		 5ef3J-6fydA:
undetectable
5ef3K-6fydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA605_1
(CHITINASE)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		3 / 3 TRP A 275
ILE A 289
SER A 288
 None
 1.02A 5gqbA-6fydA:
undetectable		 5gqbA-6fydA:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_1
(RIBOFLAVIN LYASE)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		6 / 12 ALA A  60
ALA A  64
GLY A 113
PHE A 453
VAL A 200
THR A  54
 None
None
FAD  A 600 (-3.8A)
None
FAD  A 600 (-3.9A)
None
 1.32A 5w4zA-6fydA:
undetectable		 5w4zA-6fydA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		5 / 11 GLY A 423
GLN A 457
GLU A 424
THR A 324
GLY A  82
 None
 1.27A 5w97A-6fydA:
undetectable
5w97B-6fydA:
undetectable
5w97g-6fydA:
undetectable		 5w97A-6fydA:
undetectable
5w97B-6fydA:
undetectable
5w97g-6fydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_C_RFPC502_1
(RIFAMPIN
MONOOXYGENASE)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		5 / 12 VAL A 139
GLY A 195
VAL A 191
THR A 202
GLY A 113
 FAD  A 600 (-4.4A)
None
None
None
FAD  A 600 (-3.8A)
 1.17A 6brdC-6fydA:
0.9		 6brdC-6fydA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_1
(NS3 PROTEASE)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		5 / 9 HIS A  83
LEU A  47
ARG A  74
ALA A  49
ASP A  93
 FAD  A 600 ( 4.7A)
None
None
None
None
 1.28A 6c2mB-6fydA:
undetectable		 6c2mB-6fydA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_B_REAB601_1
(RETINOIC ACID
RECEPTOR)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		5 / 10 LEU A 159
SER A 160
LEU A 117
GLY A 195
GLY A 140
 None
None
None
None
FAD  A 600 (-3.2A)
 1.09A 6eu9B-6fydA:
undetectable		 6eu9B-6fydA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_2
(-)		 6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM
(Streptomyces
maritimus) 		5 / 12 GLY A 193
GLY A 147
LEU A 146
GLY A 442
ASN A 456
 None
None
FAD  A 600 (-4.9A)
None
None
 0.91A 6gngB-6fydA:
undetectable		 6gngB-6fydA:
7.84