SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fzv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_F_FUAF704_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6fzv PROCOLLAGEN
C-ENDOPEPTIDASE
ENHANCER 1
(Homo
sapiens) 		5 / 11 SER D 192
SER D 160
LEU D  95
VAL D  72
PHE D  86
 None
 1.39A 1q23F-6fzvD:
undetectable		 1q23F-6fzvD:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6fzv PROCOLLAGEN
C-ENDOPEPTIDASE
ENHANCER 1
(Homo
sapiens) 		5 / 11 SER D 192
SER D 160
LEU D  95
VAL D  72
PHE D  86
 None
 1.30A 1q23J-6fzvD:
undetectable		 1q23J-6fzvD:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_A_FLPA1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 6fzv PROCOLLAGEN
C-ENDOPEPTIDASE
ENHANCER 1
(Homo
sapiens) 		5 / 12 VAL D 228
LEU D 227
LEU D 175
GLY D 136
LEU D 145
 None
 1.08A 2aylA-6fzvD:
undetectable		 2aylA-6fzvD:
9.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_B_FLPB2701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 6fzv PROCOLLAGEN
C-ENDOPEPTIDASE
ENHANCER 1
(Homo
sapiens) 		5 / 12 VAL D 228
LEU D 227
LEU D 175
GLY D 136
LEU D 145
 None
 1.02A 2aylB-6fzvD:
undetectable		 2aylB-6fzvD:
9.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 6fzv PROCOLLAGEN
C-ENDOPEPTIDASE
ENHANCER 1
(Homo
sapiens) 		3 / 3 ARG D 189
ASP D 233
ASP D 185
 None
CA  D 302 (-3.1A)
None
 0.84A 3jb2A-6fzvD:
undetectable		 3jb2A-6fzvD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 6fzv PROCOLLAGEN
C-ENDOPEPTIDASE
ENHANCER 1
(Homo
sapiens) 		3 / 3 ARG D 189
ASP D 233
ASP D 185
 None
CA  D 302 (-3.1A)
None
 0.86A 3jb3A-6fzvD:
undetectable		 3jb3A-6fzvD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 6fzv PROCOLLAGEN
C-ENDOPEPTIDASE
ENHANCER 1
(Homo
sapiens) 		4 / 8 GLU D 225
ASN D 197
ASN D 224
ILE D 173
 None
 1.23A 3kp6A-6fzvD:
undetectable
3kp6B-6fzvD:
undetectable		 3kp6A-6fzvD:
19.21
3kp6B-6fzvD:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8W_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 6fzv PROCOLLAGEN
C-ENDOPEPTIDASE
ENHANCER 1
(Homo
sapiens) 		5 / 12 VAL D 228
LEU D 227
LEU D 175
GLY D 136
LEU D 145
 None
 1.01A 3n8wA-6fzvD:
undetectable		 3n8wA-6fzvD:
9.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_D_FLPD701_1
(CYCLOOXYGENASE-2)		 6fzv PROCOLLAGEN
C-ENDOPEPTIDASE
ENHANCER 1
(Homo
sapiens) 		5 / 12 VAL D 228
LEU D 227
LEU D 175
GLY D 136
LEU D 145
 None
 1.06A 3pghD-6fzvD:
undetectable		 3pghD-6fzvD:
9.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RS0_A_IBPA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6fzv PROCOLLAGEN
C-ENDOPEPTIDASE
ENHANCER 1
(Homo
sapiens) 		5 / 9 VAL D 228
LEU D 227
LEU D 175
GLY D 136
LEU D 145
 None
 0.93A 4rs0A-6fzvD:
undetectable		 4rs0A-6fzvD:
9.96