SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6g1i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1873_0
(FPRA)		 6g1i -
(-) 		3 / 3 ASP A 141
ASP A 258
LYS A 265
 MN  A 409 (-2.6A)
None
OHI  A 264 ( 3.0A)
 0.94A 1lqtB-6g1iA:
undetectable		 1lqtB-6g1iA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1430_0
(FPRA)		 6g1i -
(-) 		3 / 3 ASP A 141
ASP A 258
LYS A 265
 MN  A 409 (-2.6A)
None
OHI  A 264 ( 3.0A)
 0.93A 1lquB-6g1iA:
undetectable		 1lquB-6g1iA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA602_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 6g1i -
(-) 		4 / 7 ASN A 344
ALA A 316
ALA A 315
ALA A 319
 None
 0.89A 3a2qA-6g1iA:
undetectable		 3a2qA-6g1iA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 6g1i -
(-) 		4 / 5 ILE A 261
TYR A 230
ARG A 268
GLY A 266
 None
None
None
OHI  A 264 ( 4.4A)
 1.24A 3b9mA-6g1iA:
undetectable		 3b9mA-6g1iA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA1001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 6g1i -
(-) 		4 / 5 LEU A 291
GLY A 290
PHE A 270
PHE A 195
 None
 0.84A 3smtA-6g1iA:
1.0		 3smtA-6g1iA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_D_CAMD502_0
(CAMPHOR
5-MONOOXYGENASE)		 6g1i -
(-) 		4 / 5 PHE A 186
LEU A 291
GLY A 290
VAL A 183
 None
 0.99A 3wrkD-6g1iA:
undetectable		 3wrkD-6g1iA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_E_PARE500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 6g1i -
(-) 		5 / 12 PHE A 220
LEU A 223
GLU A 175
TYR A 143
GLY A 260
 None
None
MN  A 409 (-2.7A)
None
None
 1.47A 4qb9E-6g1iA:
undetectable		 4qb9E-6g1iA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_A_AG2A506_1
(HOMOSPERMIDINE
SYNTHASE)		 6g1i -
(-) 		4 / 6 ARG A 284
ASP A 285
VAL A 308
ASP A 312
 None
 0.98A 4xqeA-6g1iA:
undetectable		 4xqeA-6g1iA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 6g1i -
(-) 		4 / 6 ARG A 284
ASP A 285
VAL A 308
ASP A 312
 None
 0.95A 4xqeB-6g1iA:
undetectable		 4xqeB-6g1iA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_A_AG2A505_1
(HOMOSPERMIDINE
SYNTHASE)		 6g1i -
(-) 		4 / 8 ARG A 284
ASP A 285
VAL A 308
ASP A 312
 None
 0.96A 4xqgA-6g1iA:
undetectable		 4xqgA-6g1iA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 6g1i -
(-) 		4 / 8 ARG A 284
ASP A 285
VAL A 308
ASP A 312
 None
 0.95A 4xqgB-6g1iA:
undetectable		 4xqgB-6g1iA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 6g1i -
(-) 		5 / 12 GLU A 175
LYS A 171
GLY A 260
LEU A 223
ALA A 200
 MN  A 409 (-2.7A)
None
None
None
None
 1.19A 5kbwA-6g1iA:
undetectable		 5kbwA-6g1iA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)		 6g1i -
(-) 		4 / 7 PRO A 222
ILE A 168
ILE A 169
ILE A 267
 None
None
None
OHI  A 264 ( 4.0A)
 0.84A 5murB-6g1iA:
undetectable		 5murB-6g1iA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_2
(-)		 6g1i -
(-) 		5 / 12 GLY A 198
GLY A 318
LEU A 317
GLY A 293
PRO A 345
 None
 1.03A 6gngB-6g1iA:
undetectable		 6gngB-6g1iA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IEY_A_CLMA401_0
(ESTERASE)		 6g1i -
(-) 		5 / 11 ILE A 267
ALA A 274
LEU A 291
GLY A 293
ALA A 229
 OHI  A 264 ( 4.0A)
None
None
None
None
 1.25A 6ieyA-6g1iA:
undetectable
6ieyB-6g1iA:
undetectable		 6ieyA-6g1iA:
undetectable
6ieyB-6g1iA:
undetectable