SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6g1o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_G_AG2G7003_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 6g1o -
(-) 		5 / 6 LEU A 348
ASP A 347
GLY A 345
ILE A 240
ARG A 244
 None
 1.50A 1mt1G-6g1oA:
undetectable
1mt1J-6g1oA:
undetectable		 1mt1G-6g1oA:
undetectable
1mt1J-6g1oA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_B_BEZB143_0
(PUTATIVE REDOX
PROTEIN)		 6g1o -
(-) 		4 / 6 THR A 230
ALA A 266
ARG A 333
PRO A 232
 None
 1.33A 2ql8A-6g1oA:
undetectable
2ql8B-6g1oA:
undetectable		 2ql8A-6g1oA:
undetectable
2ql8B-6g1oA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)		 6g1o -
(-) 		4 / 6 LEU A 145
LEU A 148
ILE A  35
ARG A  32
 None
 0.92A 2rlfC-6g1oA:
undetectable
2rlfD-6g1oA:
undetectable		 2rlfC-6g1oA:
undetectable
2rlfD-6g1oA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		 6g1o -
(-) 		4 / 6 THR A 340
ASN A 344
GLY A 345
ILE A 212
 None
 0.90A 3w9tF-6g1oA:
undetectable		 3w9tF-6g1oA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3Q_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 6g1o -
(-) 		4 / 7 LEU A 449
VAL A 258
TYR A 379
TYR A  99
 None
 1.13A 4b3qA-6g1oA:
1.0		 4b3qA-6g1oA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 6g1o -
(-) 		5 / 11 SER A 101
GLY A 102
ALA A 107
LEU A 108
ALA A 466
 None
CA  A 501 ( 4.6A)
None
None
None
 1.03A 4l6v1-6g1oA:
undetectable
4l6v6-6g1oA:
undetectable		 4l6v1-6g1oA:
undetectable
4l6v6-6g1oA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_D_ACTD403_0
(PROTON-GATED ION
CHANNEL)		 6g1o -
(-) 		4 / 4 ILE A 171
ARG A 156
TYR A   4
GLU A  28
 None
 1.28A 4zzbD-6g1oA:
undetectable		 4zzbD-6g1oA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_E_ACTE406_0
(PROTON-GATED ION
CHANNEL)		 6g1o -
(-) 		4 / 5 ILE A 171
ARG A 156
TYR A   4
GLU A  28
 None
 1.25A 4zzcE-6g1oA:
undetectable		 4zzcE-6g1oA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 6g1o -
(-) 		5 / 12 GLN A 211
ILE A 257
VAL A 256
VAL A 365
LEU A 377
 CA  A 501 ( 4.7A)
None
None
None
None
 1.20A 5ergB-6g1oA:
undetectable		 5ergB-6g1oA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 6g1o -
(-) 		5 / 12 ILE A 257
VAL A 256
GLY A 345
VAL A 365
LEU A 377
 None
 1.16A 5ergB-6g1oA:
undetectable		 5ergB-6g1oA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 6g1o -
(-) 		5 / 12 ILE A 445
HIS A 448
GLU A 352
ALA A 375
ILE A 182
 None
 1.00A 5ih0A-6g1oA:
undetectable		 5ih0A-6g1oA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_D_ACTD305_0
(CARBONIC ANHYDRASE 4)		 6g1o -
(-) 		4 / 5 ALA A 346
ALA A 259
ILE A 240
LEU A 237
 None
 0.57A 5jncD-6g1oA:
undetectable		 5jncD-6g1oA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_C_SAMC201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 6g1o -
(-) 		5 / 12 ILE A  78
GLY A  76
LEU A 133
SER A 101
LEU A 108
 None
 1.12A 5twjC-6g1oA:
undetectable		 5twjC-6g1oA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_2
(ADENOSYLHOMOCYSTEINA
SE)		 6g1o -
(-) 		4 / 5 THR A 451
GLU A 352
THR A 353
HIS A 357
 None
 1.29A 5utuH-6g1oA:
2.1		 5utuH-6g1oA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ESM_A_PZEA307_1
(MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9)		 6g1o -
(-) 		3 / 3 TYR A 379
HIS A 448
PHE A 435
 None
 0.83A 6esmA-6g1oA:
undetectable		 6esmA-6g1oA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_Q_PCFQ202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 6g1o -
(-) 		4 / 6 TYR A   4
ILE A  35
ALA A  30
ARG A  32
 None
 0.96A 6hu9m-6g1oA:
undetectable
6hu9q-6g1oA:
undetectable		 6hu9m-6g1oA:
undetectable
6hu9q-6g1oA:
undetectable