SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6g21'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)		 6g21 PROBABLE FERULOYL
ESTERASE B-2
(Aspergillus
oryzae) 		4 / 7 PHE A 469
GLY A 427
ILE A 416
GLY A 424
 None
 0.80A 11gsB-6g21A:
undetectable		 11gsB-6g21A:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 6g21 PROBABLE FERULOYL
ESTERASE B-2
(Aspergillus
oryzae) 		4 / 8 GLY A  91
TYR A 320
SER A 169
HIS A 421
 None
 1.00A 1ax9A-6g21A:
12.5		 1ax9A-6g21A:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JFF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 6g21 PROBABLE FERULOYL
ESTERASE B-2
(Aspergillus
oryzae) 		5 / 12 VAL A  55
ASP A  54
SER A 105
LEU A  37
GLY A  32
 None
 1.04A 1jffB-6g21A:
undetectable		 1jffB-6g21A:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)		 6g21 PROBABLE FERULOYL
ESTERASE B-2
(Aspergillus
oryzae) 		4 / 8 GLY A  91
TYR A 320
SER A 169
HIS A 421
 None
 0.95A 1maaD-6g21A:
10.0		 1maaD-6g21A:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA1_1
(CES1 PROTEIN)		 6g21 PROBABLE FERULOYL
ESTERASE B-2
(Aspergillus
oryzae) 		5 / 12 GLY A  90
GLY A  91
SER A 169
LEU A  92
HIS A 421
 None
 0.86A 1ya4A-6g21A:
12.5		 1ya4A-6g21A:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_1
(CES1 PROTEIN)		 6g21 PROBABLE FERULOYL
ESTERASE B-2
(Aspergillus
oryzae) 		5 / 12 GLY A  90
GLY A  91
SER A 169
LEU A  92
HIS A 421
 None
 0.81A 1ya4B-6g21A:
10.0		 1ya4B-6g21A:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 6g21 PROBABLE FERULOYL
ESTERASE B-2
(Aspergillus
oryzae) 		4 / 7 GLY A  91
TYR A 320
SER A 169
HIS A 421
 None
 1.05A 2ackA-6g21A:
12.7		 2ackA-6g21A:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AKE_A_TRPA479_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 6g21 PROBABLE FERULOYL
ESTERASE B-2
(Aspergillus
oryzae) 		5 / 12 TYR A 165
THR A  87
GLY A  88
GLY A  90
THR A 170
 None
 1.23A 2akeA-6g21A:
undetectable		 2akeA-6g21A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA601_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 6g21 PROBABLE FERULOYL
ESTERASE B-2
(Aspergillus
oryzae) 		5 / 12 TYR A 165
THR A  87
GLY A  88
GLY A  90
THR A 170
 None
 1.23A 2azxA-6g21A:
undetectable		 2azxA-6g21A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)		 6g21 PROBABLE FERULOYL
ESTERASE B-2
(Aspergillus
oryzae) 		4 / 8 TYR A 327
ASP A 323
SER A 122
HIS A 118
 None
 1.34A 2bteA-6g21A:
undetectable		 2bteA-6g21A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 6g21 PROBABLE FERULOYL
ESTERASE B-2
(Aspergillus
oryzae) 		5 / 12 VAL A  55
ASP A  54
SER A 105
LEU A  37
GLY A  32
 None
 1.04A 2hxfB-6g21A:
undetectable		 2hxfB-6g21A:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXH_B_TA1B601_1
(TUBULIN BETA CHAIN)		 6g21 PROBABLE FERULOYL
ESTERASE B-2
(Aspergillus
oryzae) 		5 / 12 VAL A  55
ASP A  54
SER A 105
LEU A  37
GLY A  32
 None
 1.04A 2hxhB-6g21A:
undetectable		 2hxhB-6g21A:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P4N_B_TA1B601_1
(TUBULIN BETA CHAIN)		 6g21 PROBABLE FERULOYL
ESTERASE B-2
(Aspergillus
oryzae) 		5 / 12 VAL A  55
ASP A  54
SER A 105
LEU A  37
GLY A  32
 None
 1.04A 2p4nB-6g21A:
1.7		 2p4nB-6g21A:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_A_LEUA1887_0
(AMINOACYL-TRNA
SYNTHETASE)		 6g21 PROBABLE FERULOYL
ESTERASE B-2
(Aspergillus
oryzae) 		4 / 8 TYR A 327
ASP A 323
SER A 122
HIS A 118
 None
 1.22A 2v0gA-6g21A:
undetectable		 2v0gA-6g21A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN1_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 6g21 PROBABLE FERULOYL
ESTERASE B-2
(Aspergillus
oryzae) 		4 / 6 LEU A  72
SER A 163
PHE A 186
ASP A 187
 None
 0.81A 2vn1B-6g21A:
undetectable		 2vn1B-6g21A:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WBE_B_TA1B1439_1
(TUBULIN BETA-2B
CHAIN)		 6g21 PROBABLE FERULOYL
ESTERASE B-2
(Aspergillus
oryzae) 		5 / 12 VAL A  55
ASP A  54
SER A 105
LEU A  37
GLY A  32
 None
 1.04A 2wbeB-6g21A:
1.7		 2wbeB-6g21A:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCO_B_TA1B601_1
(BOVINE BETA TUBULIN)		 6g21 PROBABLE FERULOYL
ESTERASE B-2
(Aspergillus
oryzae) 		5 / 12 VAL A  55
ASP A  54
SER A 105
LEU A  37
GLY A  32
 None
 1.04A 3dcoB-6g21A:
undetectable		 3dcoB-6g21A:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EDL_B_TA1B601_1
(BETA TUBULIN)		 6g21 PROBABLE FERULOYL
ESTERASE B-2
(Aspergillus
oryzae) 		5 / 12 VAL A  55
ASP A  54
SER A 105
LEU A  37
GLY A  32
 None
 1.04A 3edlB-6g21A:
1.7		 3edlB-6g21A:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_1
(PUTATIVE RRNA
METHYLASE)		 6g21 PROBABLE FERULOYL
ESTERASE B-2
(Aspergillus
oryzae) 		3 / 3 ASN A 332
ASP A 323
GLN A 319
 None
 0.73A 3eeyC-6g21A:
undetectable		 3eeyC-6g21A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_1
(PUTATIVE RRNA
METHYLASE)		 6g21 PROBABLE FERULOYL
ESTERASE B-2
(Aspergillus
oryzae) 		3 / 3 ASN A 332
ASP A 323
GLN A 319
 None
 0.74A 3eeyD-6g21A:
undetectable		 3eeyD-6g21A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_1
(PUTATIVE RRNA
METHYLASE)		 6g21 PROBABLE FERULOYL
ESTERASE B-2
(Aspergillus
oryzae) 		3 / 3 ASN A 332
ASP A 323
GLN A 319
 None
 0.72A 3eeyE-6g21A:
undetectable		 3eeyE-6g21A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IZ0_B_TA1B820_1
(BETA TUBULIN, CHAIN
B FROM PDB 1JFF)		 6g21 PROBABLE FERULOYL
ESTERASE B-2
(Aspergillus
oryzae) 		5 / 12 VAL A  55
ASP A  54
SER A 105
LEU A  37
GLY A  32
 None
 1.02A 3iz0B-6g21A:
undetectable		 3iz0B-6g21A:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_B_BEZB999_0
(CHOLINESTERASE)		 6g21 PROBABLE FERULOYL
ESTERASE B-2
(Aspergillus
oryzae) 		4 / 6 GLY A  90
GLY A  91
SER A 169
HIS A 421
 None
 0.77A 3o9mB-6g21A:
12.2		 3o9mB-6g21A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 6g21 PROBABLE FERULOYL
ESTERASE B-2
(Aspergillus
oryzae) 		4 / 7 TYR A 411
ILE A 363
GLY A 371
PHE A 410
 None
 0.82A 4iqqC-6g21A:
undetectable		 4iqqC-6g21A:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JVL_A_ESTA702_1
(ESTROGEN
SULFOTRANSFERASE)		 6g21 PROBABLE FERULOYL
ESTERASE B-2
(Aspergillus
oryzae) 		4 / 9 PHE A 126
HIS A 118
ILE A 199
MET A 198
 None
 1.22A 4jvlA-6g21A:
undetectable		 4jvlA-6g21A:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_A_SALA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6g21 PROBABLE FERULOYL
ESTERASE B-2
(Aspergillus
oryzae) 		4 / 8 LEU A 101
TYR A  98
GLY A 113
ALA A 114
 None
 0.69A 5f1aA-6g21A:
undetectable		 5f1aA-6g21A:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_B_SALB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6g21 PROBABLE FERULOYL
ESTERASE B-2
(Aspergillus
oryzae) 		4 / 7 LEU A 101
TYR A  98
GLY A 113
ALA A 114
 None
 0.67A 5f1aB-6g21A:
undetectable		 5f1aB-6g21A:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 6g21 PROBABLE FERULOYL
ESTERASE B-2
(Aspergillus
oryzae) 		5 / 12 TYR A 325
LEU A  92
LEU A 133
PRO A 353
PHE A 136
 None
 1.24A 5ljcA-6g21A:
undetectable		 5ljcA-6g21A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 6g21 PROBABLE FERULOYL
ESTERASE B-2
(Aspergillus
oryzae) 		4 / 7 TYR A 411
ILE A 363
GLY A 371
PHE A 410
 None
 0.76A 5nooA-6g21A:
undetectable		 5nooA-6g21A:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 6g21 PROBABLE FERULOYL
ESTERASE B-2
(Aspergillus
oryzae) 		4 / 7 TYR A 411
ILE A 363
GLY A 371
PHE A 410
 None
 0.77A 5nooB-6g21A:
undetectable		 5nooB-6g21A:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_A_ACTA703_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 6g21 PROBABLE FERULOYL
ESTERASE B-2
(Aspergillus
oryzae) 		4 / 6 ARG A  83
ALA A 110
PRO A  77
GLU A 158
 None
 1.40A 5odqA-6g21A:
2.8		 5odqA-6g21A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6g21 PROBABLE FERULOYL
ESTERASE B-2
(Aspergillus
oryzae) 		4 / 7 ILE A  16
LEU A  18
THR A  71
LEU A  72
 None
None
NAG  A 603 (-3.8A)
None
 0.92A 6nmpA-6g21A:
undetectable
6nmpJ-6g21A:
undetectable		 6nmpA-6g21A:
undetectable
6nmpJ-6g21A:
undetectable