SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6g2j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
11, MITOCHONDRIAL
NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		4 / 5 LEU M  36
LEU M  39
LEU M 453
GLY g  71
 3PE  M 504 (-4.2A)
None
3PE  M 503 ( 4.2A)
None
 0.97A 1a4lC-6g2jM:
undetectable		 1a4lC-6g2jM:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EUP_A_ASDA452_1
(CYTOCHROME P450ERYF)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		4 / 8 SER M 157
ILE M 158
LEU M 154
GLU M 123
 None
 0.89A 1eupA-6g2jM:
undetectable		 1eupA-6g2jM:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA8_0
(GRAMICIDIN A)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		3 / 4 VAL M  27
TRP M  16
TRP M  24
 None
3PE  M 505 ( 4.3A)
None
 1.39A 1gmkA-6g2jM:
undetectable
1gmkB-6g2jM:
undetectable		 1gmkA-6g2jM:
undetectable
1gmkB-6g2jM:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IA0_B_TXLB502_1
(TUBULIN BETA CHAIN)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
3, MITOCHONDRIAL
(Mus
musculus) 		5 / 12 HIS C  67
SER C 103
PHE C  72
THR C  60
GLY C  26
 None
 1.40A 1ia0B-6g2jC:
undetectable		 1ia0B-6g2jC:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_C_NIOC708_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 1,
MITOCHONDRIAL
(Mus
musculus) 		4 / 5 SER F 302
PHE F 353
GLU F 101
GLY F 100
 None
None
None
FMN  F 501 ( 4.1A)
 1.15A 1icvC-6g2jF:
undetectable
1icvD-6g2jF:
undetectable		 1icvC-6g2jF:
17.39
1icvD-6g2jF:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_D_NIOD706_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 1,
MITOCHONDRIAL
(Mus
musculus) 		4 / 5 GLU F 101
GLY F 100
SER F 302
PHE F 353
 None
FMN  F 501 ( 4.1A)
None
None
 1.16A 1icvC-6g2jF:
undetectable
1icvD-6g2jF:
undetectable		 1icvC-6g2jF:
17.39
1icvD-6g2jF:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JFF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		5 / 12 VAL M 297
LEU M 321
SER M 240
LEU M  68
GLY M 456
 None
None
None
3PE  M 503 ( 4.2A)
None
 1.18A 1jffB-6g2jM:
undetectable		 1jffB-6g2jM:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_0
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 12 GLN L 309
THR L 306
GLY L 311
THR L 288
ALA L 289
 None
 1.13A 1jg4A-6g2jL:
undetectable		 1jg4A-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHR_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 9 THR L 221
GLY L 228
GLY L 311
SER L 307
GLY L 281
 None
3PE  L 701 (-3.9A)
None
None
None
 1.30A 1jhrA-6g2jL:
undetectable		 1jhrA-6g2jL:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHY_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 9 THR L 221
GLY L 228
GLY L 311
SER L 307
GLY L 281
 None
3PE  L 701 (-3.9A)
None
None
None
 1.32A 1jhyA-6g2jL:
undetectable		 1jhyA-6g2jL:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTV_A_TESA500_1
(17
BETA-HYDROXYSTEROID
DEHYDROGENASE TYPE 1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4L
NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
6
(Mus
musculus) 		4 / 8 LEU J  19
PRO J  25
VAL J  66
GLU K  34
 None
 1.11A 1jtvA-6g2jJ:
undetectable		 1jtvA-6g2jJ:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L4N_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 9 THR L 221
GLY L 228
GLY L 311
SER L 307
GLY L 281
 None
3PE  L 701 (-3.9A)
None
None
None
 1.29A 1l4nA-6g2jL:
undetectable		 1l4nA-6g2jL:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5K_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 9 THR L 221
GLY L 228
GLY L 311
SER L 307
GLY L 281
 None
3PE  L 701 (-3.9A)
None
None
None
 1.27A 1l5kA-6g2jL:
undetectable		 1l5kA-6g2jL:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5M_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 9 THR L 221
GLY L 228
GLY L 311
SER L 307
GLY L 281
 None
3PE  L 701 (-3.9A)
None
None
None
 1.28A 1l5mA-6g2jL:
undetectable		 1l5mA-6g2jL:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 1,
MITOCHONDRIAL
(Mus
musculus) 		3 / 3 ARG F 112
ARG F  28
ARG F 108
 None
 0.78A 1l7fA-6g2jF:
undetectable		 1l7fA-6g2jF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_1
(NEURAMINIDASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 1,
MITOCHONDRIAL
(Mus
musculus) 		3 / 3 ARG F 112
ARG F  28
ARG F 108
 None
 0.80A 1l7hA-6g2jF:
undetectable		 1l7hA-6g2jF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA732_1
(ALPHA AMYLASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 1,
MITOCHONDRIAL
(Mus
musculus) 		5 / 9 GLY F 252
GLY F  64
GLY F  67
GLY F  72
ARG F  68
 None
None
FMN  F 501 (-3.1A)
FMN  F 501 ( 4.9A)
None
 0.92A 1mxdA-6g2jF:
undetectable		 1mxdA-6g2jF:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA442_1
(ALPHA AMYLASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 1,
MITOCHONDRIAL
(Mus
musculus) 		5 / 11 GLY F 252
GLY F  64
GLY F  67
GLY F  72
ARG F  68
 None
None
FMN  F 501 (-3.1A)
FMN  F 501 ( 4.9A)
None
 0.92A 1mxgA-6g2jF:
undetectable		 1mxgA-6g2jF:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_H_BEZH515_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
3, MITOCHONDRIAL
NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT 5
(Mus
musculus;
Mus
musculus) 		4 / 6 PHE C  63
ALA C  70
TYR C  28
ILE V  50
 None
 0.77A 1oniH-6g2jC:
undetectable
1oniI-6g2jC:
undetectable		 1oniH-6g2jC:
undetectable
1oniI-6g2jC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OT7_B_IU5B1002_1
(BILE ACID RECEPTOR)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		5 / 12 LEU M 216
HIS M 293
SER M 323
ILE M 286
PHE M 327
 None
 1.23A 1ot7B-6g2jM:
undetectable		 1ot7B-6g2jM:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P5Z_B_AR3B304_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		5 / 12 ILE O  31
GLU O  53
LEU O  79
GLN O  97
PHE O 134
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
None
ADP  O 401 (-3.5A)
ADP  O 401 (-3.6A)
 0.91A 1p5zB-6g2jO:
undetectable		 1p5zB-6g2jO:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P5Z_B_AR3B304_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		6 / 12 ILE O  31
GLU O  53
LEU O  79
TYR O  83
ARG O 126
PHE O 134
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
None
ADP  O 401 (-4.9A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
 1.03A 1p5zB-6g2jO:
undetectable		 1p5zB-6g2jO:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P5Z_B_AR3B304_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		5 / 12 ILE O  31
LEU O  79
GLN O  97
PHE O 134
GLU O 191
 ADP  O 401 (-4.0A)
None
ADP  O 401 (-3.5A)
ADP  O 401 (-3.6A)
ADP  O 401 (-3.2A)
 1.00A 1p5zB-6g2jO:
undetectable		 1p5zB-6g2jO:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P5Z_B_AR3B304_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		6 / 12 ILE O  31
LEU O  79
TYR O  83
ARG O 126
ASP O 131
PHE O 134
 ADP  O 401 (-4.0A)
None
ADP  O 401 (-4.9A)
ADP  O 401 ( 4.3A)
None
ADP  O 401 (-3.6A)
 0.97A 1p5zB-6g2jO:
undetectable		 1p5zB-6g2jO:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P5Z_B_AR3B304_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		6 / 12 ILE O  31
LEU O  79
TYR O  83
ARG O 126
PHE O 134
GLU O 191
 ADP  O 401 (-4.0A)
None
ADP  O 401 (-4.9A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
ADP  O 401 (-3.2A)
 0.94A 1p5zB-6g2jO:
undetectable		 1p5zB-6g2jO:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P62_B_GEOB302_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		5 / 11 ILE O  31
GLU O  53
TYR O  83
ARG O 126
PHE O 134
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
ADP  O 401 (-4.9A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
 0.79A 1p62B-6g2jO:
undetectable		 1p62B-6g2jO:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P62_B_GEOB302_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		5 / 11 ILE O  31
TYR O  83
ARG O 126
ASP O 131
PHE O 134
 ADP  O 401 (-4.0A)
ADP  O 401 (-4.9A)
ADP  O 401 ( 4.3A)
None
ADP  O 401 (-3.6A)
 1.01A 1p62B-6g2jO:
undetectable		 1p62B-6g2jO:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P62_B_GEOB302_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		5 / 11 ILE O  31
TYR O  83
ARG O 126
PHE O 134
GLU O 191
 ADP  O 401 (-4.0A)
ADP  O 401 (-4.9A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
ADP  O 401 (-3.2A)
 0.76A 1p62B-6g2jO:
undetectable		 1p62B-6g2jO:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT 5
NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
3, MITOCHONDRIAL
NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
4, MITOCHONDRIAL
(Mus
musculus) 		3 / 3 GLU C  91
TRP V 111
LYS Q 108
 None
 1.31A 1qu2A-6g2jC:
undetectable		 1qu2A-6g2jC:
5.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVT_A_PRLA311_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus;
Mus
musculus) 		4 / 8 LEU L 558
THR M 153
TYR M 152
ILE L 562
 None
None
3PE  M 501 ( 4.4A)
3PE  M 501 (-4.0A)
 1.11A 1qvtA-6g2jL:
undetectable		 1qvtA-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_1
(DNA TOPOISOMERASE II)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
9, MITOCHONDRIAL
(Mus
musculus) 		4 / 7 THR P 339
TYR P 236
TYR P 244
LEU P 241
 None
 1.07A 1qzrA-6g2jP:
undetectable		 1qzrA-6g2jP:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_2
(DNA TOPOISOMERASE II)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
9, MITOCHONDRIAL
(Mus
musculus) 		4 / 7 THR P 339
TYR P 236
TYR P 244
LEU P 241
 None
 1.08A 1qzrB-6g2jP:
undetectable		 1qzrB-6g2jP:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RV7_B_AB1B1001_1
(PROTEASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 11 ALA L 464
ILE L 329
THR L 251
ALA L  93
VAL L  96
 None
 1.15A 1rv7A-6g2jL:
undetectable
1rv7B-6g2jL:
undetectable		 1rv7A-6g2jL:
16.04
1rv7B-6g2jL:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T46_A_STIA3_2
(HOMO SAPIENS V-KIT
HARDY-ZUCKERMAN 4
FELINE SARCOMA VIRAL
ONCOGENE HOMOLOG)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 1,
MITOCHONDRIAL
(Mus
musculus) 		4 / 7 VAL F 124
VAL F 175
TYR F 137
CYH F 235
 None
 1.16A 1t46A-6g2jF:
undetectable		 1t46A-6g2jF:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUB_B_TXLB501_1
(TUBULIN)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
3, MITOCHONDRIAL
(Mus
musculus) 		5 / 12 HIS C  67
SER C 103
PHE C  72
THR C  60
GLY C  26
 None
 1.41A 1tubB-6g2jC:
undetectable		 1tubB-6g2jC:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 1,
MITOCHONDRIAL
(Mus
musculus) 		4 / 7 TYR F 137
THR F 104
GLU F 226
THR F 331
 None
 1.08A 1tv8B-6g2jF:
undetectable		 1tv8B-6g2jF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 12 LEU L 233
ALA L 236
ILE L 155
MET L 252
ILE L 100
 None
 1.08A 1tw4A-6g2jL:
undetectable		 1tw4A-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_B_CHDB1130_0
(FATTY ACID-BINDING
PROTEIN)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		5 / 12 TYR M  95
LEU M  99
LEU M 102
ILE M 225
ILE M 131
 None
 1.16A 1tw4B-6g2jM:
undetectable		 1tw4B-6g2jM:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_A_NCTA1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		4 / 8 TYR O  94
THR O 273
TYR O 101
LEU O 158
 None
 1.42A 1uw6A-6g2jO:
undetectable
1uw6B-6g2jO:
undetectable		 1uw6A-6g2jO:
12.21
1uw6B-6g2jO:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_D_NCTD1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		4 / 8 TYR O  94
THR O 273
TYR O 101
LEU O 158
 None
 1.42A 1uw6D-6g2jO:
undetectable
1uw6E-6g2jO:
undetectable		 1uw6D-6g2jO:
12.21
1uw6E-6g2jO:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_G_NCTG1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		4 / 8 TYR O  94
THR O 273
TYR O 101
LEU O 158
 None
 1.43A 1uw6G-6g2jO:
undetectable
1uw6H-6g2jO:
undetectable		 1uw6G-6g2jO:
12.21
1uw6H-6g2jO:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_P_NCTP1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		4 / 8 TYR O  94
THR O 273
TYR O 101
LEU O 158
 None
 1.42A 1uw6P-6g2jO:
undetectable
1uw6Q-6g2jO:
undetectable		 1uw6P-6g2jO:
12.21
1uw6Q-6g2jO:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_T_NCTT1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		4 / 8 LEU O 158
TYR O  94
THR O 273
TYR O 101
 None
 1.43A 1uw6P-6g2jO:
undetectable
1uw6T-6g2jO:
undetectable		 1uw6P-6g2jO:
12.21
1uw6T-6g2jO:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V2X_A_SAMA400_0
(TRNA (GM18)
METHYLTRANSFERASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 1,
MITOCHONDRIAL
(Mus
musculus) 		5 / 12 GLY F 260
ILE F 343
LEU F 295
VAL F 297
ALA F 296
 None
 0.98A 1v2xA-6g2jF:
undetectable		 1v2xA-6g2jF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_0
(VP39)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
9, MITOCHONDRIAL
(Mus
musculus) 		5 / 12 ILE P 214
GLY P 213
VAL P  34
VAL P 210
LEU P  30
 None
None
None
None
NDP  P 501 ( 4.6A)
 1.00A 1vptA-6g2jP:
undetectable		 1vptA-6g2jP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOT_A_VDNA101_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		5 / 12 LEU M 160
SER M  62
SER M 240
PHE M 203
ILE M 246
 None
 1.13A 1xotA-6g2jM:
undetectable		 1xotA-6g2jM:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XQL_B_4AXB505_1
(ALANINE RACEMASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
10
NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
5, MITOCHONDRIAL
(Mus
musculus) 		4 / 8 TYR h  59
ARG h  73
TYR p  63
TYR h  66
 None
 1.42A 1xqlA-6g2jh:
undetectable
1xqlB-6g2jh:
undetectable		 1xqlA-6g2jh:
14.24
1xqlB-6g2jh:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_1
(ANDROGEN RECEPTOR)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		5 / 12 LEU M 238
GLY M 239
MET M 294
MET M 243
ILE M 301
 None
 1.48A 1z95A-6g2jM:
undetectable		 1z95A-6g2jM:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_A_IMNA379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		5 / 12 TYR O 272
THR O 159
PRO O 161
TYR O 101
ILE O 155
 None
 1.34A 1z9hA-6g2jO:
undetectable		 1z9hA-6g2jO:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_B_IMNB381_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		5 / 12 TYR O 272
THR O 159
PRO O 161
TYR O 101
ILE O 155
 None
 1.34A 1z9hB-6g2jO:
undetectable		 1z9hB-6g2jO:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_C_IMNC379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		5 / 12 TYR O 272
THR O 159
PRO O 161
TYR O 101
ILE O 155
 None
 1.35A 1z9hC-6g2jO:
undetectable		 1z9hC-6g2jO:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A69_M_RPTM8002_1
(DNA-DIRECTED RNA
POLYMERASE BETA
CHAIN)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
3, MITOCHONDRIAL
NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
4, MITOCHONDRIAL
(Mus
musculus) 		5 / 12 ARG C 150
HIS C 160
ARG C 163
ASN Q  99
GLU Q  27
 None
 1.39A 2a69M-6g2jC:
undetectable		 2a69M-6g2jC:
5.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A7Q_A_CFBA328_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		5 / 12 GLU O  53
TYR O  83
ARG O 126
PHE O 134
TYR O 198
 ADP  O 401 ( 4.7A)
ADP  O 401 (-4.9A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
None
 0.79A 2a7qA-6g2jO:
undetectable		 2a7qA-6g2jO:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A7Q_A_CFBA328_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		5 / 12 GLU O  53
TYR O  83
GLN O  97
PHE O 134
TYR O 198
 ADP  O 401 ( 4.7A)
ADP  O 401 (-4.9A)
ADP  O 401 (-3.5A)
ADP  O 401 (-3.6A)
None
 1.06A 2a7qA-6g2jO:
undetectable		 2a7qA-6g2jO:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A7Q_A_CFBA328_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		5 / 12 TYR O  83
ARG O 126
PHE O 134
GLU O 191
TYR O 198
 ADP  O 401 (-4.9A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
ADP  O 401 (-3.2A)
None
 0.77A 2a7qA-6g2jO:
undetectable		 2a7qA-6g2jO:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A7Q_A_CFBA328_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		5 / 12 TYR O  83
GLN O  97
PHE O 134
GLU O 191
TYR O 198
 ADP  O 401 (-4.9A)
ADP  O 401 (-3.5A)
ADP  O 401 (-3.6A)
ADP  O 401 (-3.2A)
None
 0.92A 2a7qA-6g2jO:
undetectable		 2a7qA-6g2jO:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_F_SPMF1433_1
(NITROALKANE OXIDASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		5 / 11 GLN M 103
LEU M  77
LEU M  12
SER M  97
LEU M  99
 None
None
3PE  M 505 ( 4.9A)
3PE  M 505 (-3.4A)
None
 1.29A 2c12F-6g2jM:
undetectable		 2c12F-6g2jM:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1320_0
(CHLOROPEROXIDASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
4, MITOCHONDRIAL
(Mus
musculus) 		4 / 6 PHE Q  86
ILE Q  37
VAL Q  35
PHE Q  59
 None
 0.71A 2cizA-6g2jQ:
undetectable		 2cizA-6g2jQ:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
4, MITOCHONDRIAL
(Mus
musculus) 		4 / 5 ASP Q  77
LEU Q  79
MET Q  82
ARG Q  33
 None
 1.32A 2gj5A-6g2jQ:
undetectable		 2gj5A-6g2jQ:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		5 / 12 VAL M 297
LEU M 321
SER M 240
LEU M  68
GLY M 456
 None
None
None
3PE  M 503 ( 4.2A)
None
 1.19A 2hxfB-6g2jM:
undetectable		 2hxfB-6g2jM:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXH_B_TA1B601_1
(TUBULIN BETA CHAIN)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		5 / 12 VAL M 297
LEU M 321
SER M 240
LEU M  68
GLY M 456
 None
None
None
3PE  M 503 ( 4.2A)
None
 1.19A 2hxhB-6g2jM:
undetectable		 2hxhB-6g2jM:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_C_ACTC1120_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus;
Mus
musculus) 		3 / 3 LYS L 564
TYR M 148
PRO L 563
 3PE  M 501 (-2.5A)
3PE  M 501 ( 4.9A)
3PE  M 501 ( 4.6A)
 1.46A 2j9cC-6g2jL:
undetectable		 2j9cC-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_B_AZZB1211_1
(DEOXYNUCLEOSIDE
KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		6 / 12 GLU O  53
LEU O  79
TYR O  83
ARG O 126
PHE O 134
MET O 138
 ADP  O 401 ( 4.7A)
None
ADP  O 401 (-4.9A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
None
 1.07A 2jj8B-6g2jO:
undetectable		 2jj8B-6g2jO:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_B_AZZB1211_1
(DEOXYNUCLEOSIDE
KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		6 / 12 GLU O  53
LEU O  79
TYR O  83
GLN O  97
PHE O 134
MET O 138
 ADP  O 401 ( 4.7A)
None
ADP  O 401 (-4.9A)
ADP  O 401 (-3.5A)
ADP  O 401 (-3.6A)
None
 1.23A 2jj8B-6g2jO:
undetectable		 2jj8B-6g2jO:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_B_AZZB1211_1
(DEOXYNUCLEOSIDE
KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		5 / 12 LEU O  79
TYR O  83
ARG O 104
PHE O 134
MET O 138
 None
ADP  O 401 (-4.9A)
ADP  O 401 (-4.5A)
ADP  O 401 (-3.6A)
None
 1.36A 2jj8B-6g2jO:
undetectable		 2jj8B-6g2jO:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		5 / 12 GLU O  53
LEU O  79
ARG O 126
PHE O 134
MET O 138
 ADP  O 401 ( 4.7A)
None
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
None
 1.07A 2jj8C-6g2jO:
undetectable		 2jj8C-6g2jO:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		5 / 12 GLU O  53
LEU O  79
GLN O  97
PHE O 134
MET O 138
 ADP  O 401 ( 4.7A)
None
ADP  O 401 (-3.5A)
ADP  O 401 (-3.6A)
None
 1.22A 2jj8C-6g2jO:
undetectable		 2jj8C-6g2jO:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB502_1
(CYTOCHROME P450 2C8)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 10 ILE L 414
ILE L 411
ASN L 400
VAL L 315
ILE L 396
 None
 1.19A 2nnhB-6g2jL:
undetectable		 2nnhB-6g2jL:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO0_A_GEOA302_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		6 / 12 ILE O  31
GLU O  53
LEU O  79
GLN O  97
ARG O 126
PHE O 134
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
None
ADP  O 401 (-3.5A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
 0.94A 2no0A-6g2jO:
undetectable		 2no0A-6g2jO:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO0_A_GEOA302_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		6 / 12 ILE O  31
GLU O  53
LEU O  79
TYR O  83
ARG O 126
PHE O 134
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
None
ADP  O 401 (-4.9A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
 0.97A 2no0A-6g2jO:
undetectable		 2no0A-6g2jO:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO0_A_GEOA302_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		6 / 12 ILE O  31
LEU O  79
GLN O  97
ARG O 126
PHE O 134
GLU O 191
 ADP  O 401 (-4.0A)
None
ADP  O 401 (-3.5A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
ADP  O 401 (-3.2A)
 1.01A 2no0A-6g2jO:
undetectable		 2no0A-6g2jO:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO0_A_GEOA302_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		6 / 12 ILE O  31
LEU O  79
TYR O  83
ARG O 126
PHE O 134
GLU O 191
 ADP  O 401 (-4.0A)
None
ADP  O 401 (-4.9A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
ADP  O 401 (-3.2A)
 0.86A 2no0A-6g2jO:
undetectable		 2no0A-6g2jO:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO0_B_GEOB302_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		6 / 12 ILE O  31
GLU O  53
LEU O  79
GLN O  97
ARG O 126
PHE O 134
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
None
ADP  O 401 (-3.5A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
 0.96A 2no0B-6g2jO:
undetectable		 2no0B-6g2jO:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO0_B_GEOB302_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		6 / 12 ILE O  31
GLU O  53
LEU O  79
TYR O  83
ARG O 126
PHE O 134
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
None
ADP  O 401 (-4.9A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
 0.98A 2no0B-6g2jO:
undetectable		 2no0B-6g2jO:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO0_B_GEOB302_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		6 / 12 ILE O  31
LEU O  79
GLN O  97
ARG O 126
PHE O 134
GLU O 191
 ADP  O 401 (-4.0A)
None
ADP  O 401 (-3.5A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
ADP  O 401 (-3.2A)
 1.01A 2no0B-6g2jO:
undetectable		 2no0B-6g2jO:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO0_B_GEOB302_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		6 / 12 ILE O  31
LEU O  79
TYR O  83
ARG O 126
PHE O 134
GLU O 191
 ADP  O 401 (-4.0A)
None
ADP  O 401 (-4.9A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
ADP  O 401 (-3.2A)
 0.83A 2no0B-6g2jO:
undetectable		 2no0B-6g2jO:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO6_A_ETVA302_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		8 / 12 ILE O  31
GLU O  53
LEU O  79
TYR O  83
ARG O 126
ASP O 131
PHE O 134
TYR O 198
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
None
ADP  O 401 (-4.9A)
ADP  O 401 ( 4.3A)
None
ADP  O 401 (-3.6A)
None
 1.23A 2no6A-6g2jO:
undetectable		 2no6A-6g2jO:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO6_A_ETVA302_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		7 / 12 ILE O  31
GLU O  53
LEU O  79
TYR O  83
GLN O  97
PHE O 134
TYR O 198
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
None
ADP  O 401 (-4.9A)
ADP  O 401 (-3.5A)
ADP  O 401 (-3.6A)
None
 1.07A 2no6A-6g2jO:
undetectable		 2no6A-6g2jO:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO6_A_ETVA302_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		6 / 12 ILE O  31
GLU O  53
TYR O  83
ARG O 104
ARG O 126
ASP O 131
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
ADP  O 401 (-4.9A)
ADP  O 401 (-4.5A)
ADP  O 401 ( 4.3A)
None
 1.27A 2no6A-6g2jO:
undetectable		 2no6A-6g2jO:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO6_B_ETVB302_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		7 / 11 ILE O  31
GLU O  53
LEU O  79
TYR O  83
ARG O 126
ASP O 131
PHE O 134
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
None
ADP  O 401 (-4.9A)
ADP  O 401 ( 4.3A)
None
ADP  O 401 (-3.6A)
 1.12A 2no6B-6g2jO:
undetectable		 2no6B-6g2jO:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO6_B_ETVB302_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		7 / 11 ILE O  31
GLU O  53
LEU O  79
TYR O  83
GLN O  97
ARG O 126
PHE O 134
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
None
ADP  O 401 (-4.9A)
ADP  O 401 (-3.5A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
 1.01A 2no6B-6g2jO:
undetectable		 2no6B-6g2jO:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO6_B_ETVB302_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		6 / 11 ILE O  31
GLU O  53
TYR O  83
ARG O 104
ARG O 126
ASP O 131
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
ADP  O 401 (-4.9A)
ADP  O 401 (-4.5A)
ADP  O 401 ( 4.3A)
None
 1.25A 2no6B-6g2jO:
undetectable		 2no6B-6g2jO:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOA_A_3TCA302_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		6 / 12 ILE O  31
GLU O  53
LEU O  79
TYR O  83
ARG O 126
PHE O 134
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
None
ADP  O 401 (-4.9A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
 0.99A 2noaA-6g2jO:
undetectable		 2noaA-6g2jO:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOA_A_3TCA302_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		6 / 12 ILE O  31
GLU O  53
LEU O  79
TYR O  83
GLN O  97
PHE O 134
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
None
ADP  O 401 (-4.9A)
ADP  O 401 (-3.5A)
ADP  O 401 (-3.6A)
 1.01A 2noaA-6g2jO:
undetectable		 2noaA-6g2jO:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOA_A_3TCA302_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		5 / 12 ILE O  31
GLU O  53
TYR O  83
ARG O 104
ARG O 126
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
ADP  O 401 (-4.9A)
ADP  O 401 (-4.5A)
ADP  O 401 ( 4.3A)
 1.08A 2noaA-6g2jO:
undetectable		 2noaA-6g2jO:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOA_B_3TCB302_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		6 / 11 ILE O  31
GLU O  53
LEU O  79
GLN O  97
ARG O 126
PHE O 134
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
None
ADP  O 401 (-3.5A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
 0.94A 2noaB-6g2jO:
undetectable		 2noaB-6g2jO:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOA_B_3TCB302_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		6 / 11 ILE O  31
GLU O  53
LEU O  79
TYR O  83
ARG O 126
PHE O 134
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
None
ADP  O 401 (-4.9A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
 0.97A 2noaB-6g2jO:
undetectable		 2noaB-6g2jO:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOA_B_3TCB302_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		5 / 11 ILE O  31
GLU O  53
TYR O  83
ARG O 104
ARG O 126
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
ADP  O 401 (-4.9A)
ADP  O 401 (-4.5A)
ADP  O 401 ( 4.3A)
 1.10A 2noaB-6g2jO:
undetectable		 2noaB-6g2jO:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOA_B_3TCB302_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		6 / 11 ILE O  31
LEU O  79
TYR O  83
ARG O 126
ASP O 131
PHE O 134
 ADP  O 401 (-4.0A)
None
ADP  O 401 (-4.9A)
ADP  O 401 ( 4.3A)
None
ADP  O 401 (-3.6A)
 0.98A 2noaB-6g2jO:
undetectable		 2noaB-6g2jO:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOA_B_3TCB302_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		5 / 11 ILE O  31
TYR O  83
ARG O 104
ARG O 126
ASP O 131
 ADP  O 401 (-4.0A)
ADP  O 401 (-4.9A)
ADP  O 401 (-4.5A)
ADP  O 401 ( 4.3A)
None
 1.09A 2noaB-6g2jO:
undetectable		 2noaB-6g2jO:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
11, MITOCHONDRIAL
NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
5, MITOCHONDRIAL
(Mus
musculus;
Mus
musculus) 		3 / 3 PHE h  21
PHE g  60
PHE g  64
 None
 0.87A 2od9A-6g2jh:
undetectable		 2od9A-6g2jh:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P4N_B_TA1B601_1
(TUBULIN BETA CHAIN)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		5 / 12 VAL M 297
LEU M 321
SER M 240
LEU M  68
GLY M 456
 None
None
None
3PE  M 503 ( 4.2A)
None
 1.18A 2p4nB-6g2jM:
undetectable		 2p4nB-6g2jM:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA701_0
(FERROCHELATASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 1,
MITOCHONDRIAL
(Mus
musculus) 		4 / 8 MET F 111
LEU F 149
VAL F 228
GLY F 121
 None
 0.88A 2qd5A-6g2jF:
undetectable		 2qd5A-6g2jF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1103_0
(FERROCHELATASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 1,
MITOCHONDRIAL
(Mus
musculus) 		4 / 8 MET F 111
LEU F 149
VAL F 228
GLY F 121
 None
 0.87A 2qd5B-6g2jF:
undetectable		 2qd5B-6g2jF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
11, MITOCHONDRIAL
NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
5, MITOCHONDRIAL
(Mus
musculus;
Mus
musculus) 		3 / 3 PHE h  21
PHE g  60
PHE g  64
 None
 0.87A 2qqgA-6g2jh:
undetectable		 2qqgA-6g2jh:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXO_B_TACB1211_1
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 1,
MITOCHONDRIAL
(Mus
musculus) 		5 / 11 LEU F 306
LEU F 322
CYH F 312
VAL F 334
ILE F 335
 None
 1.21A 2uxoB-6g2jF:
undetectable		 2uxoB-6g2jF:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		4 / 8 THR L 241
PRO L 242
VAL L 243
SER L 244
 None
 0.92A 2v32C-6g2jL:
undetectable
2v32D-6g2jL:
undetectable		 2v32C-6g2jL:
undetectable
2v32D-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VPP_A_GEOA1210_1
(DEOXYNUCLEOSIDE
KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		5 / 12 ILE O  31
GLU O  53
GLN O  97
ARG O 126
PHE O 134
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
ADP  O 401 (-3.5A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
 1.02A 2vppA-6g2jO:
undetectable		 2vppA-6g2jO:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VPP_A_GEOA1210_1
(DEOXYNUCLEOSIDE
KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		5 / 12 ILE O  31
GLU O  53
TYR O  83
ARG O 126
PHE O 134
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
ADP  O 401 (-4.9A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
 0.87A 2vppA-6g2jO:
undetectable		 2vppA-6g2jO:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VPP_B_GEOB1207_1
(DEOXYNUCLEOSIDE
KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		5 / 12 ILE O  31
GLU O  53
GLN O  97
ARG O 126
PHE O 134
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
ADP  O 401 (-3.5A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
 1.00A 2vppB-6g2jO:
undetectable		 2vppB-6g2jO:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VPP_B_GEOB1207_1
(DEOXYNUCLEOSIDE
KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		5 / 12 ILE O  31
GLU O  53
TYR O  83
ARG O 126
PHE O 134
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
ADP  O 401 (-4.9A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
 0.87A 2vppB-6g2jO:
undetectable		 2vppB-6g2jO:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W1B_A_DXCA2034_0
(ACRIFLAVIN
RESISTANCE PROTEIN B)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		3 / 3 PHE L  32
SER L  24
LEU L  20
 None
 0.78A 2w1bA-6g2jL:
undetectable		 2w1bA-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WBE_B_TA1B1439_1
(TUBULIN BETA-2B
CHAIN)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		5 / 12 VAL M 297
LEU M 321
SER M 240
LEU M  68
GLY M 456
 None
None
None
3PE  M 503 ( 4.2A)
None
 1.19A 2wbeB-6g2jM:
undetectable		 2wbeB-6g2jM:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
10
(Mus
musculus;
Mus
musculus) 		5 / 12 HIS L 323
THR L 475
GLU p 118
GLU L  60
ASP L  83
 None
 1.22A 2xinA-6g2jL:
undetectable		 2xinA-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_B_SORB397_0
(D-XYLOSE ISOMERASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
10
(Mus
musculus;
Mus
musculus) 		5 / 12 HIS L 323
THR L 475
GLU p 118
GLU L  60
ASP L  83
 None
 1.22A 2xinB-6g2jL:
undetectable		 2xinB-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_C_SORC397_0
(D-XYLOSE ISOMERASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
10
(Mus
musculus;
Mus
musculus) 		5 / 12 HIS L 323
THR L 475
GLU p 118
GLU L  60
ASP L  83
 None
 1.19A 2xinC-6g2jL:
undetectable		 2xinC-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
10
(Mus
musculus;
Mus
musculus) 		5 / 12 HIS L 323
THR L 475
GLU p 118
GLU L  60
ASP L  83
 None
 1.22A 2xinD-6g2jL:
undetectable		 2xinD-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRL_A_DXTA1211_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 12 SER L 249
PRO L 240
VAL L 243
LEU L 121
ILE L 100
 None
 1.07A 2xrlA-6g2jL:
undetectable		 2xrlA-6g2jL:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_B_CTCB1385_0
(TETX2 PROTEIN)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 1,
MITOCHONDRIAL
(Mus
musculus) 		4 / 8 GLY F 417
PRO F 299
GLY F 301
MET F 337
 None
 0.95A 2y6rB-6g2jF:
undetectable		 2y6rB-6g2jF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
9, MITOCHONDRIAL
(Mus
musculus) 		5 / 12 ILE P 164
GLY P 213
ALA P 208
VAL P 207
VAL P 215
 None
 0.85A 2yvlA-6g2jP:
undetectable		 2yvlA-6g2jP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
9, MITOCHONDRIAL
(Mus
musculus) 		5 / 12 ILE P 164
GLY P 213
ALA P 208
VAL P 207
VAL P 215
 None
 0.88A 2yvlB-6g2jP:
undetectable		 2yvlB-6g2jP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_D_SAMD603_0
(HYPOTHETICAL PROTEIN)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
9, MITOCHONDRIAL
(Mus
musculus) 		5 / 12 ILE P 164
GLY P 213
ALA P 208
VAL P 207
VAL P 215
 None
 0.84A 2yvlD-6g2jP:
undetectable		 2yvlD-6g2jP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZI9_A_CL9A401_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		6 / 12 ILE O  31
GLU O  53
TYR O  83
ARG O 104
ARG O 126
GLU O 191
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
ADP  O 401 (-4.9A)
ADP  O 401 (-4.5A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.2A)
 0.96A 2zi9A-6g2jO:
undetectable		 2zi9A-6g2jO:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZI9_A_CL9A401_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		6 / 12 ILE O  31
GLU O  53
TYR O  83
ARG O 126
GLU O 191
TYR O 198
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
ADP  O 401 (-4.9A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.2A)
None
 0.89A 2zi9A-6g2jO:
undetectable		 2zi9A-6g2jO:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZI9_A_CL9A401_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		6 / 12 ILE O  31
GLU O  53
TYR O  83
GLN O  97
GLU O 191
TYR O 198
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
ADP  O 401 (-4.9A)
ADP  O 401 (-3.5A)
ADP  O 401 (-3.2A)
None
 0.94A 2zi9A-6g2jO:
undetectable		 2zi9A-6g2jO:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZI9_B_CL9B401_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		5 / 12 ILE O  31
GLU O  53
TYR O  83
ARG O 104
GLU O 191
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
ADP  O 401 (-4.9A)
ADP  O 401 (-4.5A)
ADP  O 401 (-3.2A)
 1.14A 2zi9B-6g2jO:
undetectable		 2zi9B-6g2jO:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZI9_B_CL9B401_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		7 / 12 ILE O  31
GLU O  53
TYR O  83
GLN O  97
PHE O 134
GLU O 191
TYR O 198
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
ADP  O 401 (-4.9A)
ADP  O 401 (-3.5A)
ADP  O 401 (-3.6A)
ADP  O 401 (-3.2A)
None
 1.09A 2zi9B-6g2jO:
undetectable		 2zi9B-6g2jO:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIA_A_CL9A401_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		7 / 12 ILE O  31
GLU O  53
LEU O  79
TYR O  83
ARG O 104
ARG O 126
GLU O 191
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
None
ADP  O 401 (-4.9A)
ADP  O 401 (-4.5A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.2A)
 1.01A 2ziaA-6g2jO:
undetectable		 2ziaA-6g2jO:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIA_A_CL9A401_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		8 / 12 ILE O  31
GLU O  53
LEU O  79
TYR O  83
ARG O 126
PHE O 134
GLU O 191
TYR O 198
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
None
ADP  O 401 (-4.9A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
ADP  O 401 (-3.2A)
None
 0.98A 2ziaA-6g2jO:
undetectable		 2ziaA-6g2jO:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIA_A_CL9A401_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		8 / 12 ILE O  31
GLU O  53
LEU O  79
TYR O  83
GLN O  97
PHE O 134
GLU O 191
TYR O 198
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
None
ADP  O 401 (-4.9A)
ADP  O 401 (-3.5A)
ADP  O 401 (-3.6A)
ADP  O 401 (-3.2A)
None
 1.03A 2ziaA-6g2jO:
undetectable		 2ziaA-6g2jO:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIA_B_CL9B401_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		6 / 12 ILE O  31
GLU O  53
LEU O  79
TYR O  83
ARG O 104
GLU O 191
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
None
ADP  O 401 (-4.9A)
ADP  O 401 (-4.5A)
ADP  O 401 (-3.2A)
 1.06A 2ziaB-6g2jO:
undetectable		 2ziaB-6g2jO:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIA_B_CL9B401_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		8 / 12 ILE O  31
GLU O  53
LEU O  79
TYR O  83
GLN O  97
PHE O 134
GLU O 191
TYR O 198
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
None
ADP  O 401 (-4.9A)
ADP  O 401 (-3.5A)
ADP  O 401 (-3.6A)
ADP  O 401 (-3.2A)
None
 1.01A 2ziaB-6g2jO:
undetectable		 2ziaB-6g2jO:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A7E_A_SAMA216_1
(CATECHOL
O-METHYLTRANSFERASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 1,
MITOCHONDRIAL
(Mus
musculus) 		4 / 6 GLY F 368
ILE F 399
ILE F 395
ASP F 370
 None
 0.96A 3a7eA-6g2jF:
undetectable		 3a7eA-6g2jF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_3
(PHOSPHOLIPASE A2)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
3, MITOCHONDRIAL
(Mus
musculus) 		3 / 3 PRO C 167
PHE C 162
LYS C 164
 None
 1.10A 3bjwG-6g2jC:
undetectable		 3bjwG-6g2jC:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CD2_A_MTXA307_1
(DIHYDROFOLATE
REDUCTASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		6 / 12 ILE L 298
LEU L 350
ILE L 362
SER L 370
PRO L 435
ILE L 356
 None
 1.30A 3cd2A-6g2jL:
undetectable		 3cd2A-6g2jL:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCM_X_SAMX5452_0
(UNCHARACTERIZED
PROTEIN TM_1570)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 1,
MITOCHONDRIAL
(Mus
musculus) 		5 / 11 GLY F 260
ILE F 343
LEU F 295
VAL F 297
ALA F 296
 None
 0.96A 3dcmX-6g2jF:
undetectable		 3dcmX-6g2jF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCO_B_TA1B601_1
(BOVINE BETA TUBULIN)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		5 / 12 VAL M 297
LEU M 321
SER M 240
LEU M  68
GLY M 456
 None
None
None
3PE  M 503 ( 4.2A)
None
 1.18A 3dcoB-6g2jM:
undetectable		 3dcoB-6g2jM:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_B_V2HB602_0
(CYTOCHROME P450 2R1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 12 VAL L 315
ALA L 398
THR L 284
ILE L 257
MET L 277
 None
 1.20A 3dl9B-6g2jL:
undetectable		 3dl9B-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EDL_B_TA1B601_1
(BETA TUBULIN)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		5 / 12 VAL M 297
LEU M 321
SER M 240
LEU M  68
GLY M 456
 None
None
None
3PE  M 503 ( 4.2A)
None
 1.18A 3edlB-6g2jM:
undetectable		 3edlB-6g2jM:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FZG_A_SAMA300_0
(16S RRNA METHYLASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
6
NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT 1
(Mus
musculus;
Mus
musculus) 		5 / 12 GLY J  45
LEU J 124
MET J 125
VAL J 128
GLN a  42
 None
 1.24A 3fzgA-6g2jJ:
undetectable		 3fzgA-6g2jJ:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWW_A_SFXA801_1
(TRANSPORTER)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
10
NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		5 / 12 LEU M  61
GLY M 456
LEU M 457
ILE M 244
ALA p 147
 None
 1.10A 3gwwA-6g2jM:
undetectable		 3gwwA-6g2jM:
10.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 1,
MITOCHONDRIAL
NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
4, MITOCHONDRIAL
(Mus
musculus) 		5 / 12 CYH F 405
THR F 403
ILE F 185
LEU F 205
TYR Q 118
 SF4  F 502 (-2.2A)
SF4  F 502 ( 4.0A)
SF4  F 502 ( 4.2A)
None
None
 1.11A 3gwxA-6g2jF:
undetectable		 3gwxA-6g2jF:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 12 THR L 284
THR L 285
THR L 288
LEU L 310
ILE L 395
 None
 1.16A 3gwxA-6g2jL:
undetectable		 3gwxA-6g2jL:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_A_SAMA270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
6
NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4L
(Mus
musculus;
Mus
musculus) 		5 / 12 LEU K  64
ILE K  61
MET K  57
SER K  45
LEU J  51
 None
 1.35A 3gyqA-6g2jK:
undetectable
3gyqB-6g2jK:
undetectable		 3gyqA-6g2jK:
undetectable
3gyqB-6g2jK:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_A_MTXA605_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 12 ALA L 219
LEU L 260
THR L 276
ILE L 273
LEU L 210
 None
 1.15A 3hj3A-6g2jL:
undetectable		 3hj3A-6g2jL:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I9J_B_NCAB302_0
(ADP-RIBOSYL CYCLASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		4 / 6 LEU L  51
ASN L 471
SER L  91
PHE L  44
 None
 1.35A 3i9jB-6g2jL:
undetectable		 3i9jB-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_0
(UNCHARACTERIZED
PROTEIN)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
5, MITOCHONDRIAL
(Mus
musculus;
Mus
musculus) 		5 / 12 LEU M 115
VAL M 171
GLY M 172
LEU h 105
LEU M 176
 None
 0.97A 3ijdB-6g2jM:
undetectable		 3ijdB-6g2jM:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IZ0_B_TA1B820_1
(BETA TUBULIN, CHAIN
B FROM PDB 1JFF)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		5 / 12 VAL M 297
LEU M 321
SER M 240
LEU M  68
GLY M 456
 None
None
None
3PE  M 503 ( 4.2A)
None
 1.15A 3iz0B-6g2jM:
undetectable		 3iz0B-6g2jM:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 1,
MITOCHONDRIAL
(Mus
musculus) 		5 / 12 ALA F 223
PRO F 219
ALA F 211
ALA F 128
ASN F  83
 FMN  F 501 ( 4.7A)
None
None
None
None
 1.01A 3jb3A-6g2jF:
undetectable		 3jb3A-6g2jF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECLA600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		4 / 8 LEU M 360
THR M 357
ALA M 438
ILE M 445
 None
CDL  L 702 (-4.1A)
None
3PE  M 503 (-4.2A)
 0.77A 3jusA-6g2jM:
undetectable		 3jusA-6g2jM:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		4 / 8 LEU M 360
THR M 357
ALA M 438
ILE M 445
 None
CDL  L 702 (-4.1A)
None
3PE  M 503 (-4.2A)
 0.77A 3jusA-6g2jM:
undetectable		 3jusA-6g2jM:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECNB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 9 LEU L 274
THR L 275
ALA L 408
THR L 412
ILE L 399
 None
 1.42A 3jusB-6g2jL:
undetectable		 3jusB-6g2jL:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_A_ACRA720_1
(ALPHA-AMYLASE, SUSG)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		4 / 7 TYR O 198
GLU O 136
LEU O 199
ASN O  30
 None
 1.19A 3k8mA-6g2jO:
undetectable		 3k8mA-6g2jO:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_A_PNNA5001_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		4 / 8 ASN M 366
THR M 322
LEU M 444
SER M 372
 None
None
None
3PE  M 503 ( 4.3A)
 1.16A 3kp2A-6g2jM:
undetectable
3kp2B-6g2jM:
undetectable		 3kp2A-6g2jM:
undetectable
3kp2B-6g2jM:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M7R_A_VDXA425_1
(VITAMIN D3 RECEPTOR)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4L
NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
6
(Mus
musculus) 		5 / 12 LEU K  75
LEU K  78
VAL K  79
SER K  82
VAL J  65
 None
 1.31A 3m7rA-6g2jK:
undetectable		 3m7rA-6g2jK:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_B_VORB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 11 VAL L  92
SER L  91
ILE L 472
ALA L 464
THR L 387
 None
 1.13A 3mdtB-6g2jL:
undetectable		 3mdtB-6g2jL:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_A_AC2A301_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		6 / 9 ILE O  31
GLU O  53
GLN O  97
ARG O 126
PHE O 134
TYR O 198
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
ADP  O 401 (-3.5A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
None
 0.88A 3mjrA-6g2jO:
undetectable		 3mjrA-6g2jO:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_B_AC2B401_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		5 / 9 ILE O  31
GLU O  53
ARG O 126
ASP O 131
PHE O 134
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
ADP  O 401 ( 4.3A)
None
ADP  O 401 (-3.6A)
 1.14A 3mjrB-6g2jO:
undetectable		 3mjrB-6g2jO:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_D_AC2D601_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		4 / 8 GLU O  53
ARG O 126
ASP O 131
PHE O 134
 ADP  O 401 ( 4.7A)
ADP  O 401 ( 4.3A)
None
ADP  O 401 (-3.6A)
 1.09A 3mjrD-6g2jO:
undetectable		 3mjrD-6g2jO:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_D_AC2D601_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		4 / 8 GLU O  53
GLN O  97
ASP O 131
PHE O 134
 ADP  O 401 ( 4.7A)
ADP  O 401 (-3.5A)
None
ADP  O 401 (-3.6A)
 1.08A 3mjrD-6g2jO:
undetectable		 3mjrD-6g2jO:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_D_AC2D601_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		4 / 8 GLU O  53
TYR O  83
GLN O  97
ASP O 131
 ADP  O 401 ( 4.7A)
ADP  O 401 (-4.9A)
ADP  O 401 (-3.5A)
None
 1.12A 3mjrD-6g2jO:
undetectable		 3mjrD-6g2jO:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
9, MITOCHONDRIAL
(Mus
musculus) 		4 / 7 LYS P 283
VAL P 242
ILE P 287
ARG P 186
 None
 1.21A 3ms9B-6g2jP:
undetectable		 3ms9B-6g2jP:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_2
(PROTEASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		4 / 6 ILE M 412
ASP L 179
ILE M 400
GLY M 404
 None
 0.99A 3n3iA-6g2jM:
undetectable		 3n3iA-6g2jM:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_G_ACTG601_0
(CHOLINE OXIDASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
9, MITOCHONDRIAL
(Mus
musculus) 		4 / 6 ALA P 118
ILE P 117
HIS P 131
ASN P  93
 None
 1.14A 3nneG-6g2jP:
undetectable		 3nneG-6g2jP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_1
(CYTOCHROME P450 3A4)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		5 / 12 PHE M 149
LEU M 238
ILE M 230
ALA M 233
ALA M 287
 None
 1.08A 3nxuA-6g2jM:
undetectable		 3nxuA-6g2jM:
10.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_1
(CYTOCHROME P450 3A4)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		5 / 12 PHE M 149
LEU M 238
ILE M 230
ALA M 233
ALA M 287
 None
 1.08A 3nxuB-6g2jM:
undetectable		 3nxuB-6g2jM:
10.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA271_0
(PROTEIN SSM1)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 1,
MITOCHONDRIAL
(Mus
musculus) 		4 / 5 GLY F 121
GLU F 120
GLY F 125
PRO F 232
 None
 1.06A 3onnA-6g2jF:
undetectable		 3onnA-6g2jF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_2
(PROTEASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
5, MITOCHONDRIAL
NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		3 / 3 ARG h  20
LEU h  24
THR M 435
 None
 0.82A 3oxcA-6g2jh:
undetectable		 3oxcA-6g2jh:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_B_STIB4_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
9, MITOCHONDRIAL
(Mus
musculus) 		4 / 5 LYS P 283
VAL P 242
ILE P 287
ARG P 186
 None
 1.23A 3pyyB-6g2jP:
undetectable		 3pyyB-6g2jP:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_A_LLTA261_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		5 / 10 GLU O  53
LEU O  79
GLN O  97
ARG O 126
GLU O 191
 ADP  O 401 ( 4.7A)
None
ADP  O 401 (-3.5A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.2A)
 1.23A 3qeoA-6g2jO:
undetectable		 3qeoA-6g2jO:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL3_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 12 ALA L 289
LEU L 312
ILE L 493
ILE L 414
THR L 288
 None
 1.10A 3ql3A-6g2jL:
undetectable		 3ql3A-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
10
(Mus
musculus;
Mus
musculus) 		4 / 8 PHE L  55
ASN L  58
ILE p  29
PHE L   4
 None
 1.06A 3rqwI-6g2jL:
undetectable
3rqwJ-6g2jL:
undetectable		 3rqwI-6g2jL:
undetectable
3rqwJ-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
10
NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		5 / 9 SER M 180
THR M 183
THR M 182
GLY p  79
ASP p  80
 None
 1.39A 3sfuA-6g2jM:
undetectable		 3sfuA-6g2jM:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_2
(HIV-1 PROTEASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 12 LEU L 283
ALA L 408
VAL L 315
ILE L 399
ILE L 414
 None
 1.01A 3spkB-6g2jL:
undetectable		 3spkB-6g2jL:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_3
(NS3 PROTEASE, NS4A
PROTEIN)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
NADH DEHYDROGENASE
[UBIQUINONE] 1
SUBUNIT C2
(Mus
musculus) 		4 / 5 ARG d  51
PRO d  52
TYR O 308
VAL d  53
 None
None
None
3PE  M 506 (-4.3A)
 1.33A 3sufC-6g2jd:
undetectable		 3sufC-6g2jd:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_2
(HIV-1 PROTEASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
9, MITOCHONDRIAL
NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
6, MITOCHONDRIAL
(Mus
musculus) 		5 / 10 ASP R  30
VAL R  26
ILE P  46
ILE P  81
VAL R  29
 None
 0.96A 3t3cB-6g2jR:
undetectable		 3t3cB-6g2jR:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQ8_A_TOPA2001_1
(DIHYDROFOLATE
REDUCTASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 9 ALA L 289
SER L 494
ILE L 493
ILE L 414
THR L 288
 None
 1.04A 3tq8A-6g2jL:
undetectable		 3tq8A-6g2jL:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U88_A_CHDA611_0
(MENIN)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		3 / 3 SER M 157
PHE M 203
LYS M 206
 None
 0.93A 3u88A-6g2jM:
undetectable		 3u88A-6g2jM:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UM5_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 10 ILE L 468
THR L 475
SER L 476
ILE L 472
THR L 331
 None
 1.35A 3um5A-6g2jL:
undetectable		 3um5A-6g2jL:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UM5_B_CP6B709_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 10 ILE L 468
THR L 475
SER L 476
ILE L 472
THR L 331
 None
 1.36A 3um5B-6g2jL:
undetectable		 3um5B-6g2jL:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		4 / 6 ILE M 411
ARG M 346
MET M 342
LEU M 282
 None
 1.01A 3wg7N-6g2jM:
undetectable
3wg7W-6g2jM:
2.0		 3wg7N-6g2jM:
undetectable
3wg7W-6g2jM:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		4 / 6 ILE L 149
MET L 252
THR L 251
LEU L 247
 None
 1.05A 3wg7N-6g2jL:
undetectable
3wg7W-6g2jL:
undetectable		 3wg7N-6g2jL:
undetectable
3wg7W-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
10
(Mus
musculus;
Mus
musculus) 		5 / 12 HIS L 323
THR L 475
GLU p 118
GLU L  60
ASP L  83
 None
 1.26A 3ximB-6g2jL:
undetectable		 3ximB-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
10
(Mus
musculus;
Mus
musculus) 		5 / 12 HIS L 323
THR L 475
GLU p 118
GLU L  60
ASP L  83
 None
 1.28A 3ximD-6g2jL:
undetectable		 3ximD-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		4 / 4 LEU M 367
ILE M 411
GLY M 404
PHE L 152
 None
 1.00A 4dc3A-6g2jM:
undetectable		 4dc3A-6g2jM:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT 7
(Mus
musculus;
Mus
musculus) 		4 / 6 PHE o  76
ILE L 472
PRO L 473
PHE L  55
 None
 1.27A 4fgkA-6g2jo:
undetectable		 4fgkA-6g2jo:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQI_A_NIOA403_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 9 THR L 221
GLY L 228
GLY L 311
SER L 307
GLY L 281
 None
3PE  L 701 (-3.9A)
None
None
None
 1.34A 4kqiA-6g2jL:
undetectable		 4kqiA-6g2jL:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_A_MRVA1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		4 / 7 LEU M  65
THR M  69
THR M 455
MET M 310
 None
 1.14A 4mbsA-6g2jM:
undetectable		 4mbsA-6g2jM:
9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MS4_A_2C0A501_1
(GAMMA-AMINOBUTYRIC
ACID TYPE B RECEPTOR
SUBUNIT 1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		4 / 8 SER M 292
HIS M 293
ILE M 402
GLU M 378
 None
 1.14A 4ms4A-6g2jM:
undetectable		 4ms4A-6g2jM:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_2
(ADENOSINE KINASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		4 / 4 LEU M 106
SER M 101
LEU M  73
LEU M 235
 None
3PE  M 505 ( 3.8A)
None
None
 0.88A 4n09A-6g2jM:
undetectable		 4n09A-6g2jM:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_2
(ADENOSINE KINASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		4 / 5 LEU M 106
SER M 101
LEU M  73
LEU M 235
 None
3PE  M 505 ( 3.8A)
None
None
 0.86A 4n09B-6g2jM:
undetectable		 4n09B-6g2jM:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_2
(ADENOSINE KINASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		4 / 5 LEU M 106
SER M 101
LEU M  73
LEU M 235
 None
3PE  M 505 ( 3.8A)
None
None
 0.88A 4n09D-6g2jM:
undetectable		 4n09D-6g2jM:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 1,
MITOCHONDRIAL
(Mus
musculus) 		5 / 12 ALA F 223
GLY F 121
GLY F 125
ILE F 153
LEU F 149
 FMN  F 501 ( 4.7A)
None
None
None
None
 0.98A 4n49A-6g2jF:
undetectable		 4n49A-6g2jF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJG_A_SAMA302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
10
(Mus
musculus;
Mus
musculus) 		5 / 12 GLU p 127
GLU L  75
ASN p 103
VAL p 134
GLN p 130
 None
 1.41A 4njgA-6g2jp:
undetectable		 4njgA-6g2jp:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJG_B_SAMB302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
10
(Mus
musculus;
Mus
musculus) 		5 / 12 GLU p 127
GLU L  75
ASN p 103
VAL p 134
GLN p 130
 None
 1.41A 4njgB-6g2jp:
undetectable		 4njgB-6g2jp:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJH_A_SAMA302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
10
(Mus
musculus;
Mus
musculus) 		5 / 12 GLU p 127
GLU L  75
ASN p 103
VAL p 134
GLN p 130
 None
 1.48A 4njhA-6g2jp:
undetectable		 4njhA-6g2jp:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJH_B_SAMB302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
10
(Mus
musculus;
Mus
musculus) 		5 / 12 GLU p 127
GLU L  75
ASN p 103
VAL p 134
GLN p 130
 None
 1.49A 4njhB-6g2jp:
undetectable		 4njhB-6g2jp:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJI_A_SAMA302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
10
(Mus
musculus;
Mus
musculus) 		5 / 12 GLU p 127
GLU L  75
ASN p 103
VAL p 134
GLN p 130
 None
 1.48A 4njiA-6g2jp:
undetectable		 4njiA-6g2jp:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJI_B_SAMB302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
10
(Mus
musculus;
Mus
musculus) 		5 / 12 GLU p 127
GLU L  75
ASN p 103
VAL p 134
GLN p 130
 None
 1.49A 4njiB-6g2jp:
undetectable		 4njiB-6g2jp:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJJ_B_SAMB302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
10
(Mus
musculus;
Mus
musculus) 		5 / 12 GLU p 127
GLU L  75
ASN p 103
VAL p 134
GLN p 130
 None
 1.49A 4njjB-6g2jp:
undetectable		 4njjB-6g2jp:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJK_A_SAMA302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
10
(Mus
musculus;
Mus
musculus) 		5 / 12 GLU p 127
GLU L  75
ASN p 103
VAL p 134
GLN p 130
 None
 1.49A 4njkA-6g2jp:
undetectable		 4njkA-6g2jp:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJK_B_SAMB302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
10
(Mus
musculus;
Mus
musculus) 		5 / 12 GLU p 127
GLU L  75
ASN p 103
VAL p 134
GLN p 130
 None
 1.49A 4njkB-6g2jp:
undetectable		 4njkB-6g2jp:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_1
(PROTEASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 12 LEU L 283
ALA L 408
VAL L 315
ILE L 399
ILE L 414
 None
 0.94A 4njuA-6g2jL:
undetectable		 4njuA-6g2jL:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_1
(PROTEASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 12 LEU L 283
ALA L 408
VAL L 315
ILE L 399
ILE L 414
 None
 0.95A 4njuC-6g2jL:
undetectable		 4njuC-6g2jL:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_2
(ANDROGEN RECEPTOR)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		4 / 6 MET L 421
ILE L 395
ILE L 399
VAL L 315
 None
 0.91A 4olmA-6g2jL:
undetectable		 4olmA-6g2jL:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAE_A_NIZA804_1
(CATALASE-PEROXIDASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
9, MITOCHONDRIAL
(Mus
musculus) 		4 / 6 PHE P 182
LEU P 193
HIS P 288
THR P 200
 None
 1.06A 4paeA-6g2jP:
undetectable		 4paeA-6g2jP:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4L
NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
6
(Mus
musculus) 		4 / 7 GLU J  76
LEU J  87
ASN J  85
SER K  28
 None
 1.11A 4pfjA-6g2jJ:
undetectable		 4pfjA-6g2jJ:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 11 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.18A 4qvlV-6g2jL:
undetectable
4qvlb-6g2jL:
undetectable		 4qvlV-6g2jL:
17.05
4qvlb-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 11 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.18A 4qvlH-6g2jL:
undetectable
4qvlN-6g2jL:
undetectable		 4qvlH-6g2jL:
17.05
4qvlN-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 11 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.19A 4qvmV-6g2jL:
undetectable
4qvmb-6g2jL:
undetectable		 4qvmV-6g2jL:
17.05
4qvmb-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 11 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.19A 4qvmH-6g2jL:
undetectable
4qvmN-6g2jL:
undetectable		 4qvmH-6g2jL:
17.05
4qvmN-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 12 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.20A 4qvnV-6g2jL:
undetectable
4qvnb-6g2jL:
undetectable		 4qvnV-6g2jL:
17.05
4qvnb-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 12 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.19A 4qvnH-6g2jL:
undetectable
4qvnN-6g2jL:
undetectable		 4qvnH-6g2jL:
17.05
4qvnN-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 11 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.19A 4qvpV-6g2jL:
undetectable
4qvpb-6g2jL:
undetectable		 4qvpV-6g2jL:
17.05
4qvpb-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 11 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.20A 4qvpH-6g2jL:
undetectable
4qvpN-6g2jL:
undetectable		 4qvpH-6g2jL:
17.05
4qvpN-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 11 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.20A 4qvqV-6g2jL:
undetectable
4qvqb-6g2jL:
undetectable		 4qvqV-6g2jL:
17.05
4qvqb-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 11 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.21A 4qvqH-6g2jL:
undetectable
4qvqN-6g2jL:
undetectable		 4qvqH-6g2jL:
17.05
4qvqN-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 10 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.20A 4qvvV-6g2jL:
undetectable
4qvvb-6g2jL:
undetectable		 4qvvV-6g2jL:
17.05
4qvvb-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 10 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.20A 4qvvH-6g2jL:
undetectable
4qvvN-6g2jL:
undetectable		 4qvvH-6g2jL:
17.05
4qvvN-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 11 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.19A 4qvwV-6g2jL:
undetectable
4qvwb-6g2jL:
undetectable		 4qvwV-6g2jL:
17.05
4qvwb-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 11 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.20A 4qvwH-6g2jL:
undetectable
4qvwN-6g2jL:
undetectable		 4qvwH-6g2jL:
17.05
4qvwN-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 11 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.17A 4qvyV-6g2jL:
undetectable
4qvyb-6g2jL:
undetectable		 4qvyV-6g2jL:
17.05
4qvyb-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 11 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.17A 4qvyH-6g2jL:
undetectable
4qvyN-6g2jL:
undetectable		 4qvyH-6g2jL:
17.05
4qvyN-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 11 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.18A 4qw0V-6g2jL:
undetectable
4qw0b-6g2jL:
undetectable		 4qw0V-6g2jL:
17.05
4qw0b-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 11 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.18A 4qw0H-6g2jL:
undetectable
4qw0N-6g2jL:
undetectable		 4qw0H-6g2jL:
17.05
4qw0N-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 11 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.19A 4qw1V-6g2jL:
undetectable
4qw1b-6g2jL:
undetectable		 4qw1V-6g2jL:
17.05
4qw1b-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 11 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.19A 4qw1H-6g2jL:
undetectable
4qw1N-6g2jL:
undetectable		 4qw1H-6g2jL:
17.05
4qw1N-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 11 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.20A 4qw3V-6g2jL:
undetectable
4qw3b-6g2jL:
undetectable		 4qw3V-6g2jL:
17.05
4qw3b-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 11 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.20A 4qw3H-6g2jL:
undetectable
4qw3N-6g2jL:
undetectable		 4qw3H-6g2jL:
17.05
4qw3N-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 11 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.19A 4qwuV-6g2jL:
undetectable
4qwub-6g2jL:
undetectable		 4qwuV-6g2jL:
17.05
4qwub-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 11 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.18A 4qwuH-6g2jL:
undetectable
4qwuN-6g2jL:
undetectable		 4qwuH-6g2jL:
17.05
4qwuN-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_0
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
9, MITOCHONDRIAL
(Mus
musculus) 		5 / 12 GLY P 125
ALA P 124
PHE P 129
ALA P 118
VAL P 156
 None
 1.45A 4ryaA-6g2jP:
undetectable		 4ryaA-6g2jP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_B_URFB302_1
(URIDINE
PHOSPHORYLASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		4 / 7 THR M 414
MET M 355
ALA M 345
ILE M 337
 None
 0.94A 4txnB-6g2jM:
undetectable		 4txnB-6g2jM:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDA_A_DEXA1985_1
(MINERALOCORTICOID
RECEPTOR)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		5 / 12 LEU M  68
ALA M 232
MET M 294
SER M 290
LEU M 315
 3PE  M 503 ( 4.2A)
None
None
None
None
 1.46A 4udaA-6g2jM:
undetectable		 4udaA-6g2jM:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UXQ_A_0LIA1752_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
9, MITOCHONDRIAL
(Mus
musculus) 		4 / 7 VAL P  34
ILE P 166
ALA P 217
ILE P 165
 None
 0.57A 4uxqA-6g2jP:
undetectable		 4uxqA-6g2jP:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		4 / 5 PHE L 459
PRO L 453
ALA L 458
PHE L 368
 None
 1.33A 4w5oA-6g2jL:
undetectable		 4w5oA-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		5 / 12 CYH M 199
LEU M 160
LEU M 195
ALA M 163
THR M 182
 None
None
3PE  M 502 ( 4.1A)
3PE  M 502 ( 4.3A)
None
 0.97A 4x1kA-6g2jM:
undetectable
4x1kB-6g2jM:
undetectable		 4x1kA-6g2jM:
10.93
4x1kB-6g2jM:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_B_LOCB502_1
(TUBULIN BETA CHAIN)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		5 / 12 CYH M 199
LEU M 160
LEU M 195
ALA M 163
THR M 182
 None
None
3PE  M 502 ( 4.1A)
3PE  M 502 ( 4.3A)
None
 1.10A 4x1yB-6g2jM:
undetectable		 4x1yB-6g2jM:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5J_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 12 ALA L 289
LEU L 312
ILE L 493
ILE L 414
THR L 288
 None
 1.08A 4x5jA-6g2jL:
undetectable		 4x5jA-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIA_B_SORB400_0
(D-XYLOSE ISOMERASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
10
(Mus
musculus;
Mus
musculus) 		5 / 12 HIS L 323
THR L 475
GLU p 118
GLU L  60
ASP L  83
 None
 1.25A 4xiaB-6g2jL:
undetectable		 4xiaB-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_B_SALB801_1
(PROTEIN POLYBROMO-1)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 1,
MITOCHONDRIAL
(Mus
musculus) 		4 / 5 LEU F 123
TYR F 171
ALA F 128
ILE F  56
 None
 1.13A 4y03B-6g2jF:
undetectable		 4y03B-6g2jF:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_F_TR6F101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
9, MITOCHONDRIAL
NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
3, MITOCHONDRIAL
(Mus
musculus) 		4 / 5 GLY P  39
ARG P  13
GLY P  12
GLU C 186
 None
 0.88A 4z2eB-6g2jP:
undetectable
4z2eC-6g2jP:
undetectable		 4z2eB-6g2jP:
10.81
4z2eC-6g2jP:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		4 / 7 LEU M 150
THR M 129
THR M 125
THR M 153
 None
 0.87A 4z91F-6g2jM:
undetectable
4z91G-6g2jM:
undetectable
4z91H-6g2jM:
undetectable
4z91I-6g2jM:
undetectable
4z91J-6g2jM:
undetectable		 4z91F-6g2jM:
13.10
4z91G-6g2jM:
13.10
4z91H-6g2jM:
13.10
4z91I-6g2jM:
13.10
4z91J-6g2jM:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		4 / 7 THR M 125
THR M 153
LEU M 150
THR M 129
 None
 0.76A 4z91F-6g2jM:
undetectable
4z91G-6g2jM:
undetectable
4z91H-6g2jM:
undetectable
4z91I-6g2jM:
undetectable
4z91J-6g2jM:
undetectable		 4z91F-6g2jM:
13.10
4z91G-6g2jM:
13.10
4z91H-6g2jM:
13.10
4z91I-6g2jM:
13.10
4z91J-6g2jM:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZ8_A_GCSA208_1
(GLUCANASE/CHITOSANAS
E)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
10
NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
5, MITOCHONDRIAL
(Mus
musculus) 		5 / 7 GLU h  65
ARG h  73
TYR p  63
ALA h  50
TYR p  61
 None
 1.44A 4zz8A-6g2jh:
undetectable		 4zz8A-6g2jh:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_1
(SERINE/THREONINE-PRO
TEIN PHOSPHATASE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		4 / 6 LEU M 457
SER M  62
PRO M  64
PHE M 110
 None
None
3PE  M 503 ( 4.6A)
None
 1.14A 5b8iA-6g2jM:
undetectable		 5b8iA-6g2jM:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 11 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.18A 5bxnV-6g2jL:
undetectable
5bxnb-6g2jL:
undetectable		 5bxnV-6g2jL:
17.05
5bxnb-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 11 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.18A 5bxnH-6g2jL:
undetectable
5bxnN-6g2jL:
undetectable		 5bxnH-6g2jL:
17.05
5bxnN-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_F_SAMF301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		6 / 12 THR L 316
GLY L 281
GLY L 318
LEU L 317
ALA L 225
LEU L 310
 None
 1.29A 5c0oF-6g2jL:
undetectable		 5c0oF-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 9 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.21A 5cz7V-6g2jL:
undetectable
5cz7b-6g2jL:
undetectable		 5cz7V-6g2jL:
17.05
5cz7b-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 11 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.19A 5cz7H-6g2jL:
undetectable
5cz7N-6g2jL:
undetectable		 5cz7H-6g2jL:
17.05
5cz7N-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 11 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.19A 5d0xV-6g2jL:
undetectable
5d0xb-6g2jL:
undetectable		 5d0xV-6g2jL:
17.05
5d0xb-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 11 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.19A 5d0xH-6g2jL:
undetectable
5d0xN-6g2jL:
undetectable		 5d0xH-6g2jL:
17.05
5d0xN-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 12 LEU L 216
MET L 314
LEU L 283
GLY L 228
GLY L 181
 None
None
None
3PE  L 701 (-3.9A)
None
 1.14A 5d4uA-6g2jL:
undetectable		 5d4uA-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4L
(Mus
musculus) 		4 / 8 LEU K  75
GLU K  70
LEU K  33
LEU K  26
 None
 0.87A 5dxeA-6g2jK:
undetectable		 5dxeA-6g2jK:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_S_BEZS801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		4 / 6 PHE L 124
MET L 252
LEU L 153
LEU L 154
 None
None
CDL  L 702 (-4.6A)
None
 1.38A 5dzke-6g2jL:
undetectable
5dzks-6g2jL:
undetectable		 5dzke-6g2jL:
undetectable
5dzks-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		4 / 8 PHE L 335
SER L 250
ALA L 333
LEU L 339
 None
 1.20A 5dzkF-6g2jL:
undetectable
5dzkT-6g2jL:
undetectable		 5dzkF-6g2jL:
undetectable
5dzkT-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWY_E_010E6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
MAIN PROTEASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		4 / 4 THR L 316
LEU L 312
HIS L 328
GLY L 311
 None
 0.77A 5gwyA-6g2jL:
undetectable		 5gwyA-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4L
(Mus
musculus) 		4 / 6 PHE K  41
PHE K   6
SER K  45
VAL K  46
 None
 1.26A 5hesA-6g2jK:
undetectable		 5hesA-6g2jK:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_B_SAMB301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 12 PRO L 231
PHE L 529
GLY L 527
SER L 523
SER L 531
 None
 1.31A 5hfjB-6g2jL:
undetectable		 5hfjB-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_2
(FK506-BINDING
PROTEIN 1)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 1,
MITOCHONDRIAL
(Mus
musculus) 		5 / 11 TYR F 354
VAL F 415
ILE F 347
ILE F 298
ILE F 335
 None
 1.11A 5hw8G-6g2jF:
undetectable		 5hw8G-6g2jF:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 12 LEU L 310
LEU L 317
GLY L 222
ALA L 220
LEU L 217
 None
 1.11A 5ikrB-6g2jL:
undetectable		 5ikrB-6g2jL:
9.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 12 ILE L 302
PHE L 335
SER L  99
ILE L 100
PHE L 103
 None
 1.32A 5iwuA-6g2jL:
undetectable		 5iwuA-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 12 THR L 369
PHE L 335
SER L  99
ILE L 100
PHE L 103
 None
 1.36A 5iwuA-6g2jL:
undetectable		 5iwuA-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT 7
(Mus
musculus) 		4 / 6 PRO o  26
GLY o  29
ARG o 103
ARG o 114
 None
 1.40A 5jcnB-6g2jo:
undetectable		 5jcnB-6g2jo:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_C_FUAC1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
9, MITOCHONDRIAL
(Mus
musculus) 		3 / 3 VAL P  19
HIS P  37
VAL P  34
 None
 0.72A 5jmnC-6g2jP:
undetectable		 5jmnC-6g2jP:
6.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 11 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.19A 5l5fV-6g2jL:
undetectable
5l5fb-6g2jL:
undetectable		 5l5fV-6g2jL:
17.05
5l5fb-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 11 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.20A 5l5fH-6g2jL:
undetectable
5l5fN-6g2jL:
undetectable		 5l5fH-6g2jL:
17.05
5l5fN-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 12 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.19A 5l5zV-6g2jL:
undetectable
5l5zb-6g2jL:
undetectable		 5l5zV-6g2jL:
17.05
5l5zb-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 12 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.19A 5l5zH-6g2jL:
undetectable
5l5zN-6g2jL:
undetectable		 5l5zH-6g2jL:
17.05
5l5zN-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 11 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.19A 5l66V-6g2jL:
undetectable
5l66b-6g2jL:
undetectable		 5l66V-6g2jL:
17.05
5l66b-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 11 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.19A 5l66H-6g2jL:
undetectable
5l66N-6g2jL:
undetectable		 5l66H-6g2jL:
17.05
5l66N-6g2jL:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 12 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.23A 5lf3b-6g2jL:
undetectable		 5lf3b-6g2jL:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 12 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.24A 5lf3N-6g2jL:
undetectable		 5lf3N-6g2jL:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus;
Mus
musculus) 		4 / 7 LEU L 216
MET M 383
TRP L 196
MET L 137
 None
 1.46A 5ljcA-6g2jL:
undetectable		 5ljcA-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		4 / 6 LEU L 283
ILE L 273
THR L 276
MET L 214
 None
 1.42A 5ljeA-6g2jL:
undetectable		 5ljeA-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MQT_A_STIA302_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		5 / 12 ILE O  31
GLN O  97
ARG O 126
PHE O 134
GLU O 191
 ADP  O 401 (-4.0A)
ADP  O 401 (-3.5A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
ADP  O 401 (-3.2A)
 0.75A 5mqtA-6g2jO:
undetectable		 5mqtA-6g2jO:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MQT_A_STIA302_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		5 / 12 ILE O  31
PRO O  86
ARG O 126
PHE O 134
GLU O 191
 ADP  O 401 (-4.0A)
None
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.6A)
ADP  O 401 (-3.2A)
 0.88A 5mqtA-6g2jO:
undetectable		 5mqtA-6g2jO:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MQT_C_STIC302_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		6 / 12 ILE O  31
GLU O  53
GLN O  97
ARG O 126
GLU O 191
TYR O 198
 ADP  O 401 (-4.0A)
ADP  O 401 ( 4.7A)
ADP  O 401 (-3.5A)
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.2A)
None
 1.04A 5mqtC-6g2jO:
undetectable		 5mqtC-6g2jO:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MQT_C_STIC302_1
(DEOXYCYTIDINE KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		5 / 12 ILE O  31
PRO O  86
ARG O 126
GLU O 191
TYR O 198
 ADP  O 401 (-4.0A)
None
ADP  O 401 ( 4.3A)
ADP  O 401 (-3.2A)
None
 1.02A 5mqtC-6g2jO:
undetectable		 5mqtC-6g2jO:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA511_1
(PROTON-GATED ION
CHANNEL)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 1,
MITOCHONDRIAL
(Mus
musculus) 		4 / 8 ILE F 298
ILE F 343
ALA F 346
ILE F 347
 None
 0.61A 5mvmA-6g2jF:
undetectable
5mvmB-6g2jF:
undetectable		 5mvmA-6g2jF:
17.50
5mvmB-6g2jF:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_1
(METHYLTRANSFERASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
NADH DEHYDROGENASE
[UBIQUINONE] 1
SUBUNIT C1,
MITOCHONDRIAL
(Mus
musculus;
Mus
musculus) 		4 / 7 GLY O  64
PHE c   2
ASP O  65
ASN O 309
 None
 1.11A 5n5dB-6g2jO:
undetectable		 5n5dB-6g2jO:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_2
(SCRFP-TAG,GP41)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		4 / 7 GLN L 321
LEU L 394
ASP L 393
ALA L 490
 None
 1.03A 5nwvA-6g2jL:
undetectable		 5nwvA-6g2jL:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_A_ACTA701_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		3 / 3 LYS O  81
LYS O  87
SER O  88
 None
 1.34A 5odiA-6g2jO:
undetectable		 5odiA-6g2jO:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		3 / 3 VAL O  24
VAL O 122
GLN O 107
 None
 0.52A 5qgjA-6g2jO:
undetectable		 5qgjA-6g2jO:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		3 / 3 VAL O  24
VAL O 122
GLN O 107
 None
 0.57A 5qgmA-6g2jO:
undetectable		 5qgmA-6g2jO:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		3 / 3 VAL O  24
VAL O 122
GLN O 107
 None
 0.52A 5qgnA-6g2jO:
undetectable		 5qgnA-6g2jO:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		3 / 3 VAL O  24
VAL O 122
GLN O 107
 None
 0.47A 5qgyA-6g2jO:
undetectable		 5qgyA-6g2jO:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		3 / 3 VAL O  24
VAL O 122
GLN O 107
 None
 0.46A 5qgzA-6g2jO:
undetectable		 5qgzA-6g2jO:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		3 / 3 VAL O  24
VAL O 122
GLN O 107
 None
 0.46A 5qh0A-6g2jO:
undetectable		 5qh0A-6g2jO:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		3 / 3 VAL O  24
VAL O 122
GLN O 107
 None
 0.45A 5qh2A-6g2jO:
undetectable		 5qh2A-6g2jO:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		3 / 3 VAL O  24
VAL O 122
GLN O 107
 None
 0.48A 5qh3A-6g2jO:
undetectable		 5qh3A-6g2jO:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		3 / 3 VAL O  24
VAL O 122
GLN O 107
 None
 0.51A 5qh5A-6g2jO:
undetectable		 5qh5A-6g2jO:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		3 / 3 VAL O  24
VAL O 122
GLN O 107
 None
 0.49A 5qh6A-6g2jO:
undetectable		 5qh6A-6g2jO:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		3 / 3 VAL O  24
VAL O 122
GLN O 107
 None
 0.49A 5qh7A-6g2jO:
undetectable		 5qh7A-6g2jO:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH8_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		3 / 3 CYH L 402
MET L 319
ASN L 320
 None
 1.03A 5qh8A-6g2jL:
undetectable		 5qh8A-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		3 / 3 VAL O  24
VAL O 122
GLN O 107
 None
 0.46A 5qhaA-6g2jO:
undetectable		 5qhaA-6g2jO:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		3 / 3 VAL O  24
VAL O 122
GLN O 107
 None
 0.50A 5qhhA-6g2jO:
undetectable		 5qhhA-6g2jO:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 1,
MITOCHONDRIAL
(Mus
musculus) 		5 / 12 MET F  60
ILE F  56
LEU F  65
VAL F 230
THR F  45
 None
 1.18A 5tiwB-6g2jF:
undetectable		 5tiwB-6g2jF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_1
(CYTOCHROME P450 3A4)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		5 / 12 PHE M 149
LEU M 238
ILE M 230
ALA M 233
ALA M 287
 None
 0.99A 5vc0A-6g2jM:
undetectable		 5vc0A-6g2jM:
10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
9, MITOCHONDRIAL
(Mus
musculus) 		5 / 9 VAL P 317
ILE P 245
LEU P 241
PHE P  29
ILE P 171
 None
None
None
NDP  P 501 (-4.4A)
NDP  P 501 (-4.0A)
 0.90A 5vkqC-6g2jP:
undetectable
5vkqD-6g2jP:
undetectable		 5vkqC-6g2jP:
undetectable
5vkqD-6g2jP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_1
(REGULATORY PROTEIN
TETR)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus;
Mus
musculus) 		4 / 8 GLY M 397
GLU M 378
ILE L 183
ASP L 179
 None
 1.05A 5vlmD-6g2jM:
undetectable		 5vlmD-6g2jM:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
10
(Mus
musculus;
Mus
musculus) 		5 / 12 HIS L 323
THR L 475
GLU p 118
GLU L  60
ASP L  83
 None
 1.28A 5ximA-6g2jL:
undetectable		 5ximA-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
10
(Mus
musculus;
Mus
musculus) 		5 / 12 HIS L 323
THR L 475
GLU p 118
GLU L  60
ASP L  83
 None
 1.23A 5ximC-6g2jL:
undetectable		 5ximC-6g2jL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y80_A_IREA402_0
(CYCLIN-G-ASSOCIATED
KINASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		5 / 11 ALA O  39
ARG O 126
VAL O 179
ILE O  31
ILE O 202
 None
ADP  O 401 ( 4.3A)
None
ADP  O 401 (-4.0A)
None
 1.26A 5y80A-6g2jO:
undetectable		 5y80A-6g2jO:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YK2_A_ERYA501_0
(PROBABLE CONSERVED
ATP-BINDING PROTEIN
ABC TRANSPORTER)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 1,
MITOCHONDRIAL
(Mus
musculus) 		5 / 11 GLU F 189
ASP F  98
ALA F 191
PRO F 203
ILE F 185
 FMN  F 501 ( 4.8A)
FMN  F 501 (-3.9A)
None
SF4  F 502 (-4.0A)
SF4  F 502 ( 4.2A)
 1.17A 5yk2A-6g2jF:
undetectable		 5yk2A-6g2jF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL
(Mus
musculus) 		3 / 3 ASP O  28
PHE O 134
ARG O 104
 None
ADP  O 401 (-3.6A)
ADP  O 401 (-4.5A)
 0.99A 5yw0A-6g2jO:
undetectable		 5yw0A-6g2jO:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
6
NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
9, MITOCHONDRIAL
(Mus
musculus;
Mus
musculus) 		3 / 3 TYR J  78
ARG P 325
THR P 323
 None
 1.04A 5z84J-6g2jJ:
undetectable		 5z84J-6g2jJ:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		4 / 6 ILE M 411
ARG M 346
MET M 342
LEU M 282
 None
 0.96A 5z86N-6g2jM:
undetectable
5z86W-6g2jM:
1.9		 5z86N-6g2jM:
undetectable
5z86W-6g2jM:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		4 / 6 ILE M 411
ARG M 346
MET M 342
LEU M 282
 None
 1.00A 5zcoN-6g2jM:
undetectable
5zcoW-6g2jM:
1.9		 5zcoN-6g2jM:
undetectable
5zcoW-6g2jM:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 1,
MITOCHONDRIAL
(Mus
musculus) 		5 / 12 MET F  60
ILE F  56
LEU F  65
VAL F 230
THR F  45
 None
 1.17A 6b54A-6g2jF:
undetectable		 6b54A-6g2jF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_1
(RIFAMPIN
MONOOXYGENASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 1,
MITOCHONDRIAL
(Mus
musculus) 		5 / 12 PHE F 242
GLY F 121
VAL F 124
GLY F 239
GLY F 238
 None
 1.18A 6brdB-6g2jF:
undetectable		 6brdB-6g2jF:
26.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_1
(NS3 PROTEASE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
9, MITOCHONDRIAL
(Mus
musculus) 		5 / 9 VAL P   5
HIS P   2
LEU P  38
ALA P  21
VAL P  91
 None
 1.35A 6c2mB-6g2jP:
undetectable		 6c2mB-6g2jP:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4L
(Mus
musculus) 		4 / 8 LEU K  75
GLU K  70
LEU K  33
LEU K  26
 None
 0.85A 6cbzA-6g2jK:
undetectable		 6cbzA-6g2jK:
26.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_0
(ADENOSYLHOMOCYSTEINA
SE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		5 / 12 THR M 414
GLN M 415
THR M 413
ASN M 366
LEU M 282
 None
 1.40A 6exiC-6g2jM:
undetectable		 6exiC-6g2jM:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_1
(ADENOSYLHOMOCYSTEINA
SE)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
11, MITOCHONDRIAL
(Mus
musculus;
Mus
musculus) 		3 / 3 LEU M  14
ASN g  55
LEU M  77
 None
 0.68A 6exiD-6g2jM:
undetectable		 6exiD-6g2jM:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_D_ADND502_2
(-)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		4 / 5 ILE M 178
GLN M 168
THR M 173
THR M 183
 None
 1.02A 6f3mD-6g2jM:
undetectable		 6f3mD-6g2jM:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GQI_A_ACTA604_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
9, MITOCHONDRIAL
(Mus
musculus) 		4 / 6 PRO P 114
ILE P 165
GLY P 152
GLU P 153
 None
 1.10A 6gqiA-6g2jP:
undetectable		 6gqiA-6g2jP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus;
Mus
musculus) 		4 / 6 GLY M 311
LEU M 315
VAL L  69
PHE L 138
 None
None
None
CDL  L 703 (-4.9A)
 1.01A 6h7lA-6g2jM:
undetectable		 6h7lA-6g2jM:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus;
Mus
musculus) 		4 / 6 GLY M 311
LEU M 315
VAL L  69
PHE L 138
 None
None
None
CDL  L 703 (-4.9A)
 1.00A 6h7lB-6g2jM:
undetectable		 6h7lB-6g2jM:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 12 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.23A 6hwdV-6g2jL:
undetectable
6hwdb-6g2jL:
undetectable		 6hwdV-6g2jL:
18.89
6hwdb-6g2jL:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
(Mus
musculus) 		5 / 12 THR L 404
THR L 275
THR L 276
ALA L 282
THR L 412
 None
 1.23A 6hwdH-6g2jL:
undetectable
6hwdN-6g2jL:
undetectable		 6hwdH-6g2jL:
18.89
6hwdN-6g2jL:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 6g2j NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 1,
MITOCHONDRIAL
(Mus
musculus) 		5 / 12 GLY F 417
GLN F 416
LEU F 426
ILE F 343
MET F 376
 None
 1.21A 6md4A-6g2jF:
undetectable		 6md4A-6g2jF:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		 6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4
(Mus
musculus) 		4 / 6 THR M  69
LEU M  68
MET M  76
LEU M  39
 None
3PE  M 503 ( 4.2A)
None
None
 1.05A 6mvxA-6g2jM:
undetectable
6mvxB-6g2jM:
undetectable
6mvxC-6g2jM:
undetectable		 6mvxA-6g2jM:
undetectable
6mvxB-6g2jM:
undetectable
6mvxC-6g2jM:
undetectable