SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6g3w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_0
(FTSJ)		 6g3w PROBABLE INACTIVE
RECEPTOR KINASE
AT1G27190
(Arabidopsis
thaliana) 		5 / 12 GLY B 134
GLY B 135
LEU B 103
LEU B 108
LEU B 120
 None
 0.99A 1eizA-6g3wB:
undetectable		 1eizA-6g3wB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_A_SAMA206_0
(UPF0217 PROTEIN
MJ1640)		 6g3w PROBABLE INACTIVE
RECEPTOR KINASE
AT1G27190
(Arabidopsis
thaliana) 		4 / 6 LEU B 103
GLY B 105
LEU B 101
SER B 100
 None
 0.96A 3aiaA-6g3wB:
undetectable		 3aiaA-6g3wB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)		 6g3w PROBABLE INACTIVE
RECEPTOR KINASE
AT1G27190
(Arabidopsis
thaliana) 		5 / 10 SER B 100
LEU B  34
SER B  76
LEU B  77
LEU B  45
 None
 1.22A 4yiaA-6g3wB:
undetectable		 4yiaA-6g3wB:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)		 6g3w PROBABLE INACTIVE
RECEPTOR KINASE
AT1G27190
(Arabidopsis
thaliana) 		5 / 10 SER B 100
LEU B  34
SER B  76
LEU B  77
LEU B  84
 None
 1.08A 4yiaA-6g3wB:
undetectable		 4yiaA-6g3wB:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB3_A_UEGA202_1
(YFIR)		 6g3w PROBABLE INACTIVE
RECEPTOR KINASE
AT1G27190
(Arabidopsis
thaliana) 		4 / 4 LEU B 120
ILE B 116
PRO B  89
LEU B 103
 None
 1.24A 5eb3A-6g3wB:
undetectable		 5eb3A-6g3wB:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_0
(MINERALOCORTICOID
RECEPTOR)		 6g3w PROBABLE INACTIVE
RECEPTOR KINASE
AT1G27190
(Arabidopsis
thaliana) 		5 / 12 LEU B 103
LEU B 128
ASN B 131
SER B 175
LEU B 150
 None
 1.20A 5mwyA-6g3wB:
undetectable		 5mwyA-6g3wB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_0
(MINERALOCORTICOID
RECEPTOR)		 6g3w PROBABLE INACTIVE
RECEPTOR KINASE
AT1G27190
(Arabidopsis
thaliana) 		5 / 12 LEU B 165
LEU B 150
SER B 129
LEU B 128
LEU B 157
 None
 1.12A 5mwyA-6g3wB:
undetectable		 5mwyA-6g3wB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_A_ESTA601_1
(ESTROGEN RECEPTOR
BETA)		 6g3w PROBABLE INACTIVE
RECEPTOR KINASE
AT1G27190
(Arabidopsis
thaliana) 		5 / 12 LEU B  34
LEU B  31
LEU B  98
ILE B  88
LEU B 120
 None
 1.03A 5toaA-6g3wB:
undetectable		 5toaA-6g3wB:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 6g3w PROBABLE INACTIVE
RECEPTOR KINASE
AT1G27190
(Arabidopsis
thaliana) 		5 / 10 LEU B 203
ASP B 154
ILE B 185
PRO B 207
SER B 175
 None
 1.49A 6dm2B-6g3wB:
undetectable
6dm2C-6g3wB:
undetectable		 6dm2B-6g3wB:
15.66
6dm2C-6g3wB:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 6g3w PROBABLE INACTIVE
RECEPTOR KINASE
AT1G27190
(Arabidopsis
thaliana) 		5 / 10 ILE B 185
PRO B 207
SER B 175
LEU B 203
ASP B 154
 None
 1.49A 6dm2A-6g3wB:
undetectable
6dm2D-6g3wB:
undetectable		 6dm2A-6g3wB:
15.66
6dm2D-6g3wB:
15.66