SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6g45'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBK_A_RAPA225_1
(FKBP25)		 6g45 PUTATIVE MAJOR
CAPSID PROTEIN
(Cafeteriavirus-d
ependent
mavirus) 		5 / 12 LEU A 125
GLY A 419
VAL A 421
ILE A 422
ILE A 357
 None
 0.98A 1pbkA-6g45A:
undetectable		 1pbkA-6g45A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RE7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 6g45 PUTATIVE MAJOR
CAPSID PROTEIN
(Cafeteriavirus-d
ependent
mavirus) 		5 / 12 ILE A 240
ASP A 252
LYS A  80
ILE A 257
ILE A 238
 None
 1.11A 1re7A-6g45A:
undetectable		 1re7A-6g45A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_A_TRPA2003_0
(TRYPTOPHAN
HALOGENASE)		 6g45 PUTATIVE MAJOR
CAPSID PROTEIN
(Cafeteriavirus-d
ependent
mavirus) 		5 / 12 ILE A 103
PRO A 104
ILE A 123
GLU A 200
PHE A 232
 None
 1.25A 2oa1B-6g45A:
0.9		 2oa1B-6g45A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA1_0
(FERROCHELATASE)		 6g45 PUTATIVE MAJOR
CAPSID PROTEIN
(Cafeteriavirus-d
ependent
mavirus) 		5 / 11 LEU A  94
PHE A 196
ILE A  92
SER A 102
VAL A 255
 None
 1.41A 3aqiA-6g45A:
undetectable		 3aqiA-6g45A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_2
(HIV-1 PROTEASE)		 6g45 PUTATIVE MAJOR
CAPSID PROTEIN
(Cafeteriavirus-d
ependent
mavirus) 		5 / 9 ILE A 262
GLY A  51
ILE A  52
PRO A 104
VAL A 105
 None
 1.02A 3d1yB-6g45A:
undetectable		 3d1yB-6g45A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_2
(PROTEASE)		 6g45 PUTATIVE MAJOR
CAPSID PROTEIN
(Cafeteriavirus-d
ependent
mavirus) 		5 / 11 ILE A 262
GLY A  51
ILE A  52
PRO A 104
VAL A 105
 None
 0.93A 3ekxB-6g45A:
undetectable		 3ekxB-6g45A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)		 6g45 PUTATIVE MAJOR
CAPSID PROTEIN
(Cafeteriavirus-d
ependent
mavirus) 		5 / 10 LEU A 138
SER A 139
ILE A 123
PRO A 119
SER A 102
 None
 1.44A 3iluB-6g45A:
undetectable
3iluE-6g45A:
undetectable		 3iluB-6g45A:
17.91
3iluE-6g45A:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SM2_A_478A126_2
(GAG-PRO-POL
POLYPROTEIN)		 6g45 PUTATIVE MAJOR
CAPSID PROTEIN
(Cafeteriavirus-d
ependent
mavirus) 		5 / 11 ASP A 242
GLY A 417
ALA A 418
PRO A 158
TYR A 159
 None
 0.93A 3sm2B-6g45A:
undetectable		 3sm2B-6g45A:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_C_BEZC1_0
(HEME-BINDING PROTEIN
HUTZ)		 6g45 PUTATIVE MAJOR
CAPSID PROTEIN
(Cafeteriavirus-d
ependent
mavirus) 		4 / 5 TYR A 284
PHE A 218
PRO A 206
LEU A 221
 None
 1.48A 3tgvC-6g45A:
undetectable		 3tgvC-6g45A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6g45 PUTATIVE MAJOR
CAPSID PROTEIN
(Cafeteriavirus-d
ependent
mavirus) 		5 / 12 LEU A  94
PHE A 196
ILE A  92
SER A 102
VAL A 255
 None
 1.28A 3w1wA-6g45A:
undetectable		 3w1wA-6g45A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3P_A_ACTA1223_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 6g45 PUTATIVE MAJOR
CAPSID PROTEIN
(Cafeteriavirus-d
ependent
mavirus) 		4 / 5 ASP A 256
THR A 258
GLU A  78
LYS A  80
 None
 1.36A 4a3pA-6g45A:
undetectable		 4a3pA-6g45A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_D_ECND403_1
(FLAVOHEMOGLOBIN)		 6g45 PUTATIVE MAJOR
CAPSID PROTEIN
(Cafeteriavirus-d
ependent
mavirus) 		5 / 12 ILE A 103
LEU A 228
VAL A 226
LEU A  71
ILE A  41
 None
 0.95A 4g1bD-6g45A:
undetectable		 4g1bD-6g45A:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA501_1
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 6g45 PUTATIVE MAJOR
CAPSID PROTEIN
(Cafeteriavirus-d
ependent
mavirus) 		5 / 12 ASP A 433
VAL A 327
ASP A 360
ILE A 444
GLU A 292
 None
 1.40A 4i41A-6g45A:
undetectable		 4i41A-6g45A:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_A_SAMA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 6g45 PUTATIVE MAJOR
CAPSID PROTEIN
(Cafeteriavirus-d
ependent
mavirus) 		5 / 12 VAL A 192
GLY A  93
GLY A 173
ILE A 194
ILE A 238
 None
 0.94A 4iv0A-6g45A:
undetectable		 4iv0A-6g45A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 6g45 PUTATIVE MAJOR
CAPSID PROTEIN
(Cafeteriavirus-d
ependent
mavirus) 		5 / 12 VAL A 192
GLY A  93
GLY A 173
ILE A 194
ILE A 238
 None
 0.94A 4mwzB-6g45A:
undetectable		 4mwzB-6g45A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA306_1
(CHITOSANASE)		 6g45 PUTATIVE MAJOR
CAPSID PROTEIN
(Cafeteriavirus-d
ependent
mavirus) 		3 / 3 SER A 336
ASP A 347
GLN A 127
 None
 0.93A 4oltA-6g45A:
undetectable
4oltB-6g45A:
undetectable		 4oltA-6g45A:
14.68
4oltB-6g45A:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB304_1
(CHITOSANASE)		 6g45 PUTATIVE MAJOR
CAPSID PROTEIN
(Cafeteriavirus-d
ependent
mavirus) 		3 / 3 GLN A 127
SER A 336
ASP A 347
 None
 0.88A 4qwpA-6g45A:
undetectable
4qwpB-6g45A:
undetectable		 4qwpA-6g45A:
14.68
4qwpB-6g45A:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 6g45 PUTATIVE MAJOR
CAPSID PROTEIN
(Cafeteriavirus-d
ependent
mavirus) 		4 / 4 ALA A  68
PRO A 287
LEU A 125
HIS A 126
 None
 1.23A 5eskA-6g45A:
undetectable		 5eskA-6g45A:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 6g45 PUTATIVE MAJOR
CAPSID PROTEIN
(Cafeteriavirus-d
ependent
mavirus) 		4 / 5 ALA A  77
VAL A 255
PHE A 196
ILE A 240
 None
 1.02A 5of1A-6g45A:
undetectable		 5of1A-6g45A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WY0_A_SAMA800_0
(SMALL RNA
2'-O-METHYLTRANSFERA
SE)		 6g45 PUTATIVE MAJOR
CAPSID PROTEIN
(Cafeteriavirus-d
ependent
mavirus) 		6 / 12 GLY A 351
GLY A 392
ASN A 148
SER A 336
VAL A 335
ILE A 353
 None
 1.30A 5wy0A-6g45A:
undetectable		 5wy0A-6g45A:
undetectable