SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6g5s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_1
(POL POLYPROTEIN)		 6g5s -
(-) 		5 / 12 GLY A 252
ALA A 217
VAL A 207
GLY A 224
VAL A 225
 None
 0.97A 2f8gA-6g5sA:
undetectable		 2f8gA-6g5sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_2
(PROTEASE)		 6g5s -
(-) 		5 / 12 GLY A 252
ALA A 217
VAL A 207
GLY A 224
VAL A 225
 None
 1.09A 3nu5B-6g5sA:
undetectable		 3nu5B-6g5sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_1
(HIV-1 PROTEASE)		 6g5s -
(-) 		5 / 10 GLY A 252
ALA A 217
VAL A 207
GLY A 224
VAL A 225
 None
 1.01A 3oxwA-6g5sA:
undetectable		 3oxwA-6g5sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_1
(HIV-1 PROTEASE)		 6g5s -
(-) 		5 / 12 GLY A 252
ALA A 217
VAL A 207
GLY A 224
VAL A 225
 None
 0.94A 3oxxA-6g5sA:
undetectable		 3oxxA-6g5sA:
undetectable