SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6g72'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AJ6_A_NOVA1_1
(GYRASE)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
2
(Mus
musculus) 		5 / 9 ASN N 197
ILE N 265
ALA N 340
ILE N 344
THR N 268
 None
 1.24A 1aj6A-6g72N:
undetectable		 1aj6A-6g72N:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AJ6_A_NOVA1_1
(GYRASE)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
2
(Mus
musculus) 		5 / 9 ASN N 197
ILE N 265
PRO N 262
ILE N 344
THR N 268
 None
 1.15A 1aj6A-6g72N:
undetectable		 1aj6A-6g72N:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_0
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
2
(Mus
musculus) 		4 / 4 THR N 201
LEU N 194
LEU N 148
GLN N  88
 None
 1.07A 1fbmA-6g72N:
undetectable		 1fbmA-6g72N:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_A_RTLA401_0
(RETINOL DEHYDRATASE)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
2
(Mus
musculus) 		5 / 12 TYR N  59
LEU N  33
LEU N  37
SER N  36
LEU N 106
 None
 1.22A 1fmlA-6g72N:
undetectable		 1fmlA-6g72N:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_B_RTLB501_0
(RETINOL DEHYDRATASE)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
2
(Mus
musculus) 		5 / 12 TYR N  59
LEU N  33
LEU N  37
SER N  36
LEU N 106
 None
 1.21A 1fmlB-6g72N:
undetectable		 1fmlB-6g72N:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_1
(DNA GYRASE SUBUNIT B)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
2
(Mus
musculus) 		5 / 12 ASN N 197
ILE N 265
PRO N 262
ILE N 344
THR N 268
 None
 1.18A 1kijB-6g72N:
undetectable		 1kijB-6g72N:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_2
(ADENOSINE KINASE)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
7, MITOCHONDRIAL
NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
8, MITOCHONDRIAL
(Mus
musculus) 		4 / 4 SER B 128
LEU I 149
TYR I 120
GLY B 132
 SF4  B 201 (-2.8A)
None
None
None
 1.33A 1liiA-6g72B:
undetectable		 1liiA-6g72B:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 2,
MITOCHONDRIAL
(Mus
musculus) 		4 / 4 ALA E  44
VAL E  47
ALA E  45
HIS E  42
 None
 1.20A 1q23A-6g72E:
undetectable		 1q23A-6g72E:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG1_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
13
(Mus
musculus) 		3 / 3 TRP Z 115
VAL Z 116
PRO Z 117
 None
 0.99A 1rg1A-6g72Z:
undetectable		 1rg1A-6g72Z:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH0_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
13
(Mus
musculus) 		3 / 3 TRP Z 115
VAL Z 116
PRO Z 117
 None
 1.00A 1rh0A-6g72Z:
undetectable		 1rh0A-6g72Z:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9A_A_BEZA306_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 2,
MITOCHONDRIAL
NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 3,
MITOCHONDRIAL
(Mus
musculus;
Mus
musculus) 		5 / 11 GLY E 185
PRO E 186
TYR s  32
HIS s  37
HIS s  38
 None
 1.10A 1s9aA-6g72E:
undetectable		 1s9aA-6g72E:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9A_B_BEZB307_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 2,
MITOCHONDRIAL
NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 3,
MITOCHONDRIAL
(Mus
musculus;
Mus
musculus) 		5 / 12 GLY E 185
PRO E 186
TYR s  32
HIS s  37
HIS s  38
 None
 1.14A 1s9aB-6g72E:
undetectable		 1s9aB-6g72E:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_A_BEZA881_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 2,
MITOCHONDRIAL
NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 3,
MITOCHONDRIAL
(Mus
musculus;
Mus
musculus) 		5 / 11 GLY E 185
PRO E 186
TYR s  32
HIS s  37
HIS s  38
 None
 1.09A 1tmxA-6g72E:
undetectable		 1tmxA-6g72E:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_B_BEZB882_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 2,
MITOCHONDRIAL
NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 3,
MITOCHONDRIAL
(Mus
musculus;
Mus
musculus) 		5 / 12 GLY E 185
PRO E 186
TYR s  32
HIS s  37
HIS s  38
 None
 1.16A 1tmxB-6g72E:
undetectable		 1tmxB-6g72E:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
2
(Mus
musculus) 		5 / 11 LEU N  99
LEU N 102
THR N 201
ASN N 204
LEU N 148
 None
 1.28A 2ft9A-6g72N:
undetectable		 2ft9A-6g72N:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HC4_A_VDXA525_2
(VITAMIN D RECEPTOR)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
2
(Mus
musculus) 		4 / 7 LEU N 249
LEU N 248
ILE N 227
TYR N 298
 None
 1.07A 2hc4A-6g72N:
undetectable		 2hc4A-6g72N:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_F_TACF3888_1
(ELONGATION FACTOR
EF-TU)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
1
(Mus
musculus) 		4 / 7 SER H 109
SER H 110
VAL H 113
LEU H 285
 None
 0.99A 2hdnE-6g72H:
undetectable
2hdnF-6g72H:
undetectable
2hdnH-6g72H:
undetectable		 2hdnE-6g72H:
16.44
2hdnF-6g72H:
12.54
2hdnH-6g72H:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_H_TACH4888_1
(ELONGATION FACTOR
EF-TU)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
1
(Mus
musculus) 		4 / 7 SER H 110
VAL H 113
LEU H 285
SER H 109
 None
 0.95A 2hdnF-6g72H:
undetectable
2hdnG-6g72H:
undetectable
2hdnH-6g72H:
undetectable		 2hdnF-6g72H:
12.54
2hdnG-6g72H:
16.44
2hdnH-6g72H:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HZQ_A_STRA300_1
(APOLIPOPROTEIN D)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT 8
(Mus
musculus) 		4 / 7 ALA X  66
TYR X  31
ASN X  63
LEU X  24
 None
 1.20A 2hzqA-6g72X:
undetectable		 2hzqA-6g72X:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
13
NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
5
(Mus
musculus;
Mus
musculus) 		4 / 7 ILE Z  85
ARG Z  81
PRO e  93
GLY e  99
 None
 1.18A 2pnjB-6g72Z:
undetectable		 2pnjB-6g72Z:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDM_B_AGGB1462_1
(INTEGRIN ALPHA-IIB
INTEGRIN BETA-3)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
1
NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
3
(Mus
musculus) 		5 / 12 PHE A  62
LEU H 289
SER H 115
TYR H 114
SER H 112
 None
 1.44A 2vdmA-6g72A:
undetectable
2vdmB-6g72A:
undetectable		 2vdmA-6g72A:
10.36
2vdmB-6g72A:
10.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_2
(PROGESTERONE
RECEPTOR)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
2
(Mus
musculus) 		4 / 7 LEU N 202
LEU N 191
MET N  21
MET N 187
 None
 1.25A 2w8yA-6g72N:
undetectable		 2w8yA-6g72N:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1376_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
11
(Mus
musculus) 		4 / 7 GLY Y  66
ALA Y  67
MET Y  68
LEU Y  71
 None
 0.60A 2wekB-6g72Y:
undetectable		 2wekB-6g72Y:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
11
(Mus
musculus) 		5 / 11 ILE Y  91
GLY Y  92
TYR Y  89
PHE Y  69
GLY Y 118
 None
 1.37A 2y7kA-6g72Y:
undetectable		 2y7kA-6g72Y:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_C_SALC1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
11
(Mus
musculus) 		5 / 12 ILE Y  91
GLY Y  92
TYR Y  89
PHE Y  69
GLY Y 118
 None
 1.32A 2y7kC-6g72Y:
undetectable		 2y7kC-6g72Y:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 2,
MITOCHONDRIAL
(Mus
musculus) 		5 / 12 VAL E 154
ILE E 100
VAL E 102
LEU E 120
THR E 119
 None
 0.85A 3fw3A-6g72E:
undetectable		 3fw3A-6g72E:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 2,
MITOCHONDRIAL
(Mus
musculus) 		5 / 12 VAL E 154
ILE E 100
VAL E 102
LEU E 120
THR E 119
 None
 0.84A 3fw3B-6g72E:
undetectable		 3fw3B-6g72E:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 6g72 NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
13
NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
1
NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
3
(Mus
musculus) 		5 / 12 THR H 297
HIS H 304
LEU H 151
ILE A  69
TYR Z  46
 None
 1.41A 3gwxB-6g72H:
undetectable		 3gwxB-6g72H:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
2, MITOCHONDRIAL
(Mus
musculus) 		3 / 3 GLU j  62
GLU j  63
TRP j  59
 None
 1.28A 3hrdA-6g72j:
undetectable
3hrdE-6g72j:
undetectable
3hrdF-6g72j:
undetectable		 3hrdA-6g72j:
9.62
3hrdE-6g72j:
9.62
3hrdF-6g72j:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
7, MITOCHONDRIAL
NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
1
(Mus
musculus;
Mus
musculus) 		3 / 3 ARG B  51
ASP H  51
ASP B  94
 None
 0.88A 3jayA-6g72B:
undetectable		 3jayA-6g72B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
7, MITOCHONDRIAL
NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
1
(Mus
musculus;
Mus
musculus) 		3 / 3 ARG B  51
ASP H  51
ASP B  94
 None
 0.84A 3jb2A-6g72B:
undetectable		 3jb2A-6g72B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
7, MITOCHONDRIAL
NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
1
(Mus
musculus;
Mus
musculus) 		3 / 3 ARG B  51
ASP H  51
ASP B  94
 None
 0.79A 3jb3A-6g72B:
undetectable		 3jb3A-6g72B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_D_TPFD490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
1
(Mus
musculus) 		4 / 8 PHE H  56
ALA H 221
THR H 229
LEU H  83
 None
 1.04A 3l4dD-6g72H:
undetectable		 3l4dD-6g72H:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_A_AICA375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
2
(Mus
musculus) 		5 / 11 LEU N 149
ASN N  96
LEU N 102
LEU N 194
LEU N 191
 None
 1.27A 3ndvA-6g72N:
undetectable
3ndvB-6g72N:
undetectable		 3ndvA-6g72N:
11.54
3ndvB-6g72N:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_B_AICB376_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
2
(Mus
musculus) 		5 / 11 LEU N 194
LEU N 191
LEU N 149
ASN N  96
LEU N 102
 None
 1.31A 3ndvA-6g72N:
undetectable
3ndvB-6g72N:
undetectable		 3ndvA-6g72N:
11.54
3ndvB-6g72N:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_C_AICC375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
2
(Mus
musculus) 		5 / 11 LEU N 149
ASN N  96
LEU N 102
LEU N 194
LEU N 191
 None
 1.31A 3ndvC-6g72N:
undetectable
3ndvD-6g72N:
undetectable		 3ndvC-6g72N:
11.54
3ndvD-6g72N:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_D_AICD374_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
2
(Mus
musculus) 		5 / 11 LEU N 194
LEU N 191
LEU N 149
ASN N  96
LEU N 102
 None
 1.28A 3ndvC-6g72N:
undetectable
3ndvD-6g72N:
undetectable		 3ndvC-6g72N:
11.54
3ndvD-6g72N:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA309_1
(BETA-LACTAMASE)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT 3
NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT 8
(Mus
musculus) 		4 / 5 ARG b  57
THR X 132
GLU X  58
GLU X  48
 None
 1.30A 3ny4A-6g72b:
undetectable		 3ny4A-6g72b:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
7, MITOCHONDRIAL
NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
8, MITOCHONDRIAL
(Mus
musculus) 		5 / 11 ALA B  63
TYR I 120
ILE I 119
GLY B 127
VAL B 143
 SF4  B 201 (-3.3A)
None
SF4  I 201 (-4.6A)
SF4  B 201 ( 4.2A)
None
 1.09A 3rukD-6g72B:
undetectable		 3rukD-6g72B:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
2
(Mus
musculus) 		5 / 12 LEU N 191
GLY N 107
ALA N  66
PRO N 138
LEU N  33
 None
 1.21A 3tm4A-6g72N:
undetectable		 3tm4A-6g72N:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
2
(Mus
musculus) 		5 / 12 LEU N 191
GLY N 107
ALA N  66
PRO N 138
LEU N  33
 None
 1.24A 3tm4B-6g72N:
undetectable		 3tm4B-6g72N:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQB_A_FOLA2001_0
(DIHYDROFOLATE
REDUCTASE)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
1
(Mus
musculus) 		5 / 11 ALA H 236
LEU H  89
ILE H 102
LEU H 150
ILE H 241
 None
 1.08A 3tqbA-6g72H:
undetectable		 3tqbA-6g72H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VN2_A_TLSA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
1
(Mus
musculus) 		5 / 12 ILE H  15
LEU H  14
LEU H 222
PHE H 224
MET H 225
 None
 1.15A 3vn2A-6g72H:
undetectable		 3vn2A-6g72H:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACHG301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT 6
NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT 4
NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT 9
(Mus
musculus;
Mus
musculus;
Mus
musculus) 		4 / 8 TYR m  50
THR n 171
ARG i  18
LEU i  14
 None
 1.18A 3wipG-6g72m:
undetectable
3wipH-6g72m:
undetectable		 3wipG-6g72m:
undetectable
3wipH-6g72m:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_J_ACHJ301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
1
NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
13
(Mus
musculus;
Mus
musculus) 		4 / 8 ARG Z  56
LEU Z  59
TYR H 248
THR H 167
 None
 1.17A 3wipF-6g72Z:
undetectable
3wipJ-6g72Z:
undetectable		 3wipF-6g72Z:
undetectable
3wipJ-6g72Z:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_J_ACHJ301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT 6
NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT 4
NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT 9
(Mus
musculus;
Mus
musculus;
Mus
musculus) 		4 / 8 ARG i  18
LEU i  14
TYR m  50
THR n 171
 None
 1.22A 3wipF-6g72i:
undetectable
3wipJ-6g72i:
undetectable		 3wipF-6g72i:
undetectable
3wipJ-6g72i:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_B_SAMB301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
11
(Mus
musculus) 		5 / 12 GLY Y  66
GLY Y  28
LEU Y  27
LYS Y  20
TYR Y  89
 None
 1.09A 4lg1B-6g72Y:
undetectable		 4lg1B-6g72Y:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
13
NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
5
(Mus
musculus) 		4 / 5 ILE e  40
ARG Z 114
ASP e  61
GLU e  36
 None
 1.04A 4nkxC-6g72e:
undetectable		 4nkxC-6g72e:
9.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
13
NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
5
(Mus
musculus) 		4 / 5 ILE e  40
ARG Z 114
ASP e  61
GLU e  36
 None
 1.08A 4nkxD-6g72e:
undetectable		 4nkxD-6g72e:
9.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT 4
(Mus
musculus) 		4 / 5 ILE m 115
ARG m 110
ASP m 107
GLU m 112
 None
 1.26A 4nkxD-6g72m:
undetectable		 4nkxD-6g72m:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_A_ESTA2000_1
(ESTROGEN RECEPTOR)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
1
NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
3
(Mus
musculus) 		5 / 12 LEU A  72
LEU A  94
ALA A  91
LEU H 298
LEU H 155
 None
 1.13A 4pxmA-6g72A:
undetectable		 4pxmA-6g72A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RN6_A_15UA301_1
(THROMBIN HEAVY CHAIN)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
13
NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
1
(Mus
musculus) 		5 / 10 HIS H 304
LEU H 307
ALA Z  41
ALA H 178
GLY Z  45
 None
 1.36A 4rn6A-6g72H:
undetectable		 4rn6A-6g72H:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_D_NOVD2000_1
(DNA GYRASE SUBUNIT B)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
2
(Mus
musculus) 		5 / 12 ASN N 197
ILE N 265
PRO N 262
ILE N 344
THR N 268
 None
 1.26A 4uroD-6g72N:
undetectable		 4uroD-6g72N:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_B_Y70B151_1
(CEREBLON ISOFORM 4)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
7, MITOCHONDRIAL
NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
8, MITOCHONDRIAL
(Mus
musculus) 		4 / 8 PRO B 157
MET B 126
PHE I 141
TYR I  52
 None
 1.40A 4v2zB-6g72B:
undetectable		 4v2zB-6g72B:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_B_LVYB151_1
(CEREBLON ISOFORM 4)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
7, MITOCHONDRIAL
NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
8, MITOCHONDRIAL
(Mus
musculus) 		4 / 8 PRO B 157
MET B 126
PHE I 141
TYR I  52
 None
 1.45A 4v30B-6g72B:
undetectable		 4v30B-6g72B:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X61_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
1
NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
8, MITOCHONDRIAL
NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
13
(Mus
musculus;
Mus
musculus;
Mus
musculus) 		5 / 12 LEU Z  29
GLY Z  38
GLY Z  40
LEU H 176
MET I  28
 None
 1.16A 4x61A-6g72Z:
undetectable		 4x61A-6g72Z:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XYZ_A_ACTA103_0
(POLYUBIQUITIN-C)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT 8
(Mus
musculus) 		4 / 4 LEU X 114
ILE X  73
HIS X  76
VAL X 110
 None
 1.18A 4xyzA-6g72X:
undetectable		 4xyzA-6g72X:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVX_A_GMRA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
2
(Mus
musculus) 		5 / 12 LEU N 248
TYR N 293
SER N 299
LEU N 241
SER N 224
 None
 1.44A 4yvxA-6g72N:
undetectable		 4yvxA-6g72N:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
1
(Mus
musculus) 		5 / 12 LEU H 237
GLY H 101
LEU H 154
PHE H 242
THR H 145
 None
 0.97A 4ze1A-6g72H:
undetectable		 4ze1A-6g72H:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
2
(Mus
musculus) 		3 / 3 MET N 175
GLN N 174
ARG N 176
 None
 0.88A 5ewzB-6g72N:
2.6		 5ewzB-6g72N:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G08_A_Z80A1187_1
(FREQUENIN 2)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
2
(Mus
musculus) 		4 / 6 ILE N 209
TYR N 208
PHE N 216
THR N 119
 None
 0.74A 5g08A-6g72N:
undetectable		 5g08A-6g72N:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_A_SAMA801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
7, MITOCHONDRIAL
NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
8, MITOCHONDRIAL
(Mus
musculus;
Mus
musculus) 		5 / 12 GLY B 134
THR I 116
ALA B 130
LEU B 102
VAL B  98
 None
 1.18A 5hw4A-6g72B:
undetectable		 5hw4A-6g72B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_C_SAMC801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
7, MITOCHONDRIAL
NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
8, MITOCHONDRIAL
(Mus
musculus;
Mus
musculus) 		5 / 12 GLY B 134
THR I 116
ALA B 130
LEU B 102
VAL B  98
 None
 1.14A 5hw4C-6g72B:
undetectable		 5hw4C-6g72B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K50_A_ACTA1403_0
(L-THREONINE
3-DEHYDROGENASE)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
7, MITOCHONDRIAL
(Mus
musculus) 		4 / 5 SER B 125
VAL B  98
GLY B 100
ALA B 130
 None
None
SF4  B 201 ( 3.7A)
None
 1.02A 5k50A-6g72B:
undetectable		 5k50A-6g72B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
11
(Mus
musculus) 		5 / 10 THR Y  72
ALA Y  67
ALA Y  95
GLY Y  96
THR Y  99
 None
 1.06A 5lf3H-6g72Y:
undetectable
5lf3I-6g72Y:
undetectable		 5lf3H-6g72Y:
15.38
5lf3I-6g72Y:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
11
(Mus
musculus) 		5 / 10 THR Y  72
ALA Y  67
ALA Y  95
GLY Y  96
THR Y  99
 None
 1.08A 5lf3V-6g72Y:
undetectable
5lf3W-6g72Y:
undetectable		 5lf3V-6g72Y:
15.38
5lf3W-6g72Y:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
2
(Mus
musculus) 		4 / 6 LEU N 232
ILE N 297
THR N 300
MET N 175
 None
 1.43A 5ljeA-6g72N:
undetectable		 5ljeA-6g72N:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
2
(Mus
musculus) 		3 / 3 MET N 175
GLN N 174
ARG N 176
 None
 0.89A 5m35B-6g72N:
undetectable		 5m35B-6g72N:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
2
(Mus
musculus) 		3 / 3 MET N 175
GLN N 174
ARG N 176
 None
 0.89A 5m36A-6g72N:
undetectable		 5m36A-6g72N:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MRA_B_DM2B204_1
(SORCIN)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT
8, MITOCHONDRIAL
(Mus
musculus) 		4 / 6 TYR l  12
ARG l  19
ASP l  45
GLY l  44
 None
 0.94A 5mraA-6g72l:
undetectable
5mraB-6g72l:
undetectable		 5mraA-6g72l:
18.79
5mraB-6g72l:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 2,
MITOCHONDRIAL
(Mus
musculus) 		4 / 7 TYR E  98
ILE E 156
ILE E 100
ILE E 169
 None
 0.90A 5murB-6g72E:
undetectable		 5murB-6g72E:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N9X_A_THRA601_0
(ADENYLATION DOMAIN)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
7, MITOCHONDRIAL
NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
8, MITOCHONDRIAL
(Mus
musculus;
Mus
musculus) 		4 / 7 ASP I 114
GLY B 145
GLY B 133
HIS B 137
 None
 0.95A 5n9xA-6g72I:
undetectable		 5n9xA-6g72I:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_2
(WTFP-TAG,GP41)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
7, MITOCHONDRIAL
(Mus
musculus) 		3 / 3 LEU B  43
LEU B  46
TRP B  49
 None
 0.76A 5nwuA-6g72B:
undetectable		 5nwuA-6g72B:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
3
NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
1
(Mus
musculus;
Mus
musculus) 		5 / 12 PRO A  76
ILE A  69
ILE H 149
LEU H 298
THR H 297
 None
 0.89A 5tiwB-6g72A:
undetectable		 5tiwB-6g72A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIH_A_8CVA201_1
(DIHYDROFOLATE
REDUCTASE)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
1
(Mus
musculus) 		4 / 8 ALA H 236
LEU H 264
ILE H 231
THR H 239
 None
 0.83A 5uihA-6g72H:
undetectable		 5uihA-6g72H:
26.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
7, MITOCHONDRIAL
NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
8, MITOCHONDRIAL
(Mus
musculus) 		3 / 3 GLY I  65
THR I 145
PRO B 157
 None
 0.66A 5v5zA-6g72I:
undetectable		 5v5zA-6g72I:
9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_1
(CYTOCHROME P450 3A5)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT 8
(Mus
musculus) 		5 / 12 ARG X 118
PHE X  96
ILE X  73
PHE X  70
ALA X  33
 None
 1.08A 5veuA-6g72X:
undetectable		 5veuA-6g72X:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_1
(REGULATORY PROTEIN
TETR)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE]
FLAVOPROTEIN 2,
MITOCHONDRIAL
(Mus
musculus) 		4 / 8 ILE E  31
GLN E  43
VAL E  69
ASP E  22
 None
 1.12A 5vlmF-6g72E:
undetectable		 5vlmF-6g72E:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_A_8NUA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
1
(Mus
musculus) 		5 / 12 SER H 188
ILE H 187
LEU H 154
PHE H 242
LEU H 174
 None
 1.39A 6a93A-6g72H:
undetectable		 6a93A-6g72H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
7, MITOCHONDRIAL
(Mus
musculus) 		3 / 3 GLN B  92
TRP B  56
VAL B  85
 None
 1.02A 6auuA-6g72B:
undetectable		 6auuA-6g72B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNJ_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT 6
NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT 9
(Mus
musculus) 		4 / 8 THR i   4
CYH n   3
TYR i   3
LEU n 153
 None
 1.48A 6cnjD-6g72i:
undetectable
6cnjE-6g72i:
undetectable		 6cnjD-6g72i:
20.24
6cnjE-6g72i:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECF_I_DVAI3010_0
(VLM2
DODECADEPSIPEPTIDE)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT 8
NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
13
(Mus
musculus;
Mus
musculus) 		3 / 3 PHE X  42
ARG Z  80
ALA X  66
 None
 0.90A 6ecfB-6g72X:
undetectable		 6ecfB-6g72X:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA824_0
(GEPHYRIN)		 6g72 NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT 8
NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
13
(Mus
musculus;
Mus
musculus) 		4 / 4 LEU Z  83
ASP X  51
PRO X  52
ARG X  53
 None
 1.16A 6fgdA-6g72Z:
undetectable		 6fgdA-6g72Z:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
2
(Mus
musculus) 		3 / 3 MET N 175
GLN N 174
ARG N 176
 None
 0.91A 6fn9A-6g72N:
2.0		 6fn9A-6g72N:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
2
(Mus
musculus) 		3 / 3 MET N 175
GLN N 174
ARG N 176
 None
 0.92A 6fnaB-6g72N:
undetectable		 6fnaB-6g72N:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNB_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 6g72 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
2
(Mus
musculus) 		3 / 3 MET N 175
GLN N 174
ARG N 176
 None
 0.90A 6fnbA-6g72N:
undetectable		 6fnbA-6g72N:
undetectable