SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6g7x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_A_ADNA1260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 6g7x -
(-) 		5 / 10 ARG A  87
THR A  90
GLU A 179
MET A 180
GLU A 181
 PO4  A 304 ( 4.4A)
PO4  A 304 (-2.8A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
 0.32A 1jdvA-6g7xA:
34.7
1jdvD-6g7xA:
34.7		 1jdvA-6g7xA:
undetectable
1jdvD-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_B_ADNB2260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 6g7x -
(-) 		5 / 10 ARG A  87
THR A  90
GLU A 179
MET A 180
GLU A 181
 PO4  A 304 ( 4.4A)
PO4  A 304 (-2.8A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
 0.29A 1jdvB-6g7xA:
34.6
1jdvC-6g7xA:
35.5		 1jdvB-6g7xA:
undetectable
1jdvC-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_B_ADNB2260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 6g7x -
(-) 		5 / 10 ARG A  87
THR A  90
MET A 180
GLU A 181
ASP A 204
 PO4  A 304 ( 4.4A)
PO4  A 304 (-2.8A)
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
 0.95A 1jdvB-6g7xA:
34.6
1jdvC-6g7xA:
35.5		 1jdvB-6g7xA:
undetectable
1jdvC-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_D_ADND3260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 6g7x -
(-) 		5 / 10 ARG A  87
THR A  90
GLU A 179
MET A 180
GLU A 181
 PO4  A 304 ( 4.4A)
PO4  A 304 (-2.8A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
 0.33A 1jdvA-6g7xA:
34.7
1jdvD-6g7xA:
34.7		 1jdvA-6g7xA:
undetectable
1jdvD-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 6g7x -
(-) 		5 / 12 ARG A  87
GLY A  92
GLU A 179
SER A 203
ARG A  24
 PO4  A 304 ( 4.4A)
IMD  A 302 ( 4.2A)
None
None
PO4  A 304 (-3.0A)
 1.46A 1jdvE-6g7xA:
34.6
1jdvF-6g7xA:
35.5		 1jdvE-6g7xA:
undetectable
1jdvF-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 6g7x -
(-) 		5 / 12 ARG A  87
THR A  90
GLU A 181
SER A 203
ASP A 204
 PO4  A 304 ( 4.4A)
PO4  A 304 (-2.8A)
PO4  A 304 ( 4.7A)
None
None
 0.93A 1jdvE-6g7xA:
34.6
1jdvF-6g7xA:
35.5		 1jdvE-6g7xA:
undetectable
1jdvF-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 6g7x -
(-) 		7 / 12 ARG A  87
THR A  90
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 PO4  A 304 ( 4.4A)
PO4  A 304 (-2.8A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
 0.45A 1jdvE-6g7xA:
34.6
1jdvF-6g7xA:
35.5		 1jdvE-6g7xA:
undetectable
1jdvF-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		6 / 11 ARG A  87
THR A  90
GLY A  92
GLU A 179
GLU A 181
ILE A  94
 PO4  A 304 ( 4.4A)
PO4  A 304 (-2.8A)
IMD  A 302 ( 4.2A)
None
PO4  A 304 ( 4.7A)
None
 1.33A 1odiA-6g7xA:
25.3		 1odiA-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		8 / 11 MET A  64
ARG A  87
THR A  90
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 None
PO4  A 304 ( 4.4A)
PO4  A 304 (-2.8A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
 0.60A 1odiA-6g7xA:
25.3		 1odiA-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		5 / 11 MET A 180
ARG A  87
THR A  90
GLU A 181
SER A 203
 IMD  A 302 (-4.6A)
PO4  A 304 ( 4.4A)
PO4  A 304 (-2.8A)
PO4  A 304 ( 4.7A)
None
 1.48A 1odiA-6g7xA:
25.3		 1odiA-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		6 / 11 ARG A  87
THR A  90
GLY A  92
GLU A 179
GLU A 181
ILE A  94
 PO4  A 304 ( 4.4A)
PO4  A 304 (-2.8A)
IMD  A 302 ( 4.2A)
None
PO4  A 304 ( 4.7A)
None
 1.30A 1odiB-6g7xA:
35.8		 1odiB-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		8 / 11 MET A  64
ARG A  87
THR A  90
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 None
PO4  A 304 ( 4.4A)
PO4  A 304 (-2.8A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
 0.57A 1odiB-6g7xA:
35.8		 1odiB-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		5 / 11 MET A 180
ARG A  87
THR A  90
GLU A 181
SER A 203
 IMD  A 302 (-4.6A)
PO4  A 304 ( 4.4A)
PO4  A 304 (-2.8A)
PO4  A 304 ( 4.7A)
None
 1.49A 1odiB-6g7xA:
35.8		 1odiB-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		6 / 11 ARG A  87
THR A  90
GLY A  92
GLU A 179
GLU A 181
ILE A  94
 PO4  A 304 ( 4.4A)
PO4  A 304 (-2.8A)
IMD  A 302 ( 4.2A)
None
PO4  A 304 ( 4.7A)
None
 1.29A 1odiC-6g7xA:
36.0		 1odiC-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		8 / 11 MET A  64
ARG A  87
THR A  90
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 None
PO4  A 304 ( 4.4A)
PO4  A 304 (-2.8A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
 0.62A 1odiC-6g7xA:
36.0		 1odiC-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		6 / 11 ARG A  87
THR A  90
GLY A  92
GLU A 179
GLU A 181
ILE A  94
 PO4  A 304 ( 4.4A)
PO4  A 304 (-2.8A)
IMD  A 302 ( 4.2A)
None
PO4  A 304 ( 4.7A)
None
 1.33A 1odiD-6g7xA:
35.9		 1odiD-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		8 / 11 MET A  64
ARG A  87
THR A  90
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 None
PO4  A 304 ( 4.4A)
PO4  A 304 (-2.8A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
 0.59A 1odiD-6g7xA:
35.9		 1odiD-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		6 / 11 ARG A  87
THR A  90
GLY A  92
GLU A 179
GLU A 181
ILE A  94
 PO4  A 304 ( 4.4A)
PO4  A 304 (-2.8A)
IMD  A 302 ( 4.2A)
None
PO4  A 304 ( 4.7A)
None
 1.31A 1odiE-6g7xA:
35.8		 1odiE-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		8 / 11 MET A  64
ARG A  87
THR A  90
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 None
PO4  A 304 ( 4.4A)
PO4  A 304 (-2.8A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
 0.53A 1odiE-6g7xA:
35.8		 1odiE-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		6 / 11 ARG A  87
THR A  90
GLY A  92
GLU A 179
GLU A 181
ILE A  94
 PO4  A 304 ( 4.4A)
PO4  A 304 (-2.8A)
IMD  A 302 ( 4.2A)
None
PO4  A 304 ( 4.7A)
None
 1.34A 1odiF-6g7xA:
35.9		 1odiF-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		8 / 11 MET A  64
ARG A  87
THR A  90
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 None
PO4  A 304 ( 4.4A)
PO4  A 304 (-2.8A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
 0.58A 1odiF-6g7xA:
35.9		 1odiF-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		5 / 11 MET A 180
ARG A  87
THR A  90
GLU A 181
SER A 203
 IMD  A 302 (-4.6A)
PO4  A 304 ( 4.4A)
PO4  A 304 (-2.8A)
PO4  A 304 ( 4.7A)
None
 1.50A 1odiF-6g7xA:
35.9		 1odiF-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PG2_A_ADNA552_1
(METHIONYL-TRNA
SYNTHETASE)		 6g7x -
(-) 		5 / 11 GLU A 181
GLY A  63
HIS A  62
TYR A  72
VAL A  73
 PO4  A 304 ( 4.7A)
None
None
None
None
 1.09A 1pg2A-6g7xA:
undetectable		 1pg2A-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_A_ADNA1245_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		7 / 9 MET A  64
ARG A  87
GLU A 179
MET A 180
GLU A 181
SER A 203
ASP A 204
 None
PO4  A 304 ( 4.4A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
None
 0.82A 1pk7A-6g7xA:
38.1		 1pk7A-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_A_ADNA1245_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		7 / 9 MET A  64
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 None
PO4  A 304 ( 4.4A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
 0.48A 1pk7A-6g7xA:
38.1		 1pk7A-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		6 / 10 MET A  64
ARG A  87
GLU A 179
GLU A 181
SER A 203
ASP A 204
 None
PO4  A 304 ( 4.4A)
None
PO4  A 304 ( 4.7A)
None
None
 0.99A 1pk7C-6g7xA:
39.0		 1pk7C-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		7 / 10 MET A  64
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 None
PO4  A 304 ( 4.4A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
 0.61A 1pk7C-6g7xA:
39.0		 1pk7C-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_A_2FAA306_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		7 / 10 MET A  64
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 None
PO4  A 304 ( 4.4A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
 0.47A 1pk9A-6g7xA:
38.0		 1pk9A-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_B_2FAB307_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		7 / 9 MET A  64
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 None
PO4  A 304 ( 4.4A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
 0.51A 1pk9B-6g7xA:
38.3		 1pk9B-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_B_2FAB307_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		6 / 9 MET A  64
ARG A  87
MET A 180
GLU A 181
SER A 203
ASP A 204
 None
PO4  A 304 ( 4.4A)
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
None
 0.92A 1pk9B-6g7xA:
38.3		 1pk9B-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		6 / 11 ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
ILE A  94
 PO4  A 304 ( 4.4A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
 1.36A 1pk9C-6g7xA:
38.0		 1pk9C-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		7 / 11 MET A  64
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 None
PO4  A 304 ( 4.4A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
 0.57A 1pk9C-6g7xA:
38.0		 1pk9C-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		6 / 10 ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
ILE A  94
 PO4  A 304 ( 4.4A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
 1.50A 1pw7A-6g7xA:
38.1		 1pw7A-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		7 / 10 MET A  64
ARG A  87
GLU A 179
MET A 180
GLU A 181
SER A 203
ASP A 204
 None
PO4  A 304 ( 4.4A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
None
 0.86A 1pw7A-6g7xA:
38.1		 1pw7A-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		7 / 10 MET A  64
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 None
PO4  A 304 ( 4.4A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
 0.51A 1pw7A-6g7xA:
38.1		 1pw7A-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		6 / 9 ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
ILE A  94
 PO4  A 304 ( 4.4A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
 1.41A 1pw7B-6g7xA:
38.9		 1pw7B-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		6 / 9 MET A  64
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
 None
PO4  A 304 ( 4.4A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
 0.41A 1pw7B-6g7xA:
38.9		 1pw7B-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_C_RABC647_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		6 / 9 MET A  64
GLU A 179
MET A 180
GLU A 181
SER A 203
ASP A 204
 None
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
None
 0.91A 1pw7C-6g7xA:
39.0		 1pw7C-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		6 / 11 ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
ILE A  94
 PO4  A 304 ( 4.4A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
 1.42A 1vhwA-6g7xA:
39.8
1vhwD-6g7xA:
39.6		 1vhwA-6g7xA:
undetectable
1vhwD-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		6 / 11 MET A  64
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
 None
PO4  A 304 ( 4.4A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
 0.46A 1vhwA-6g7xA:
39.8
1vhwD-6g7xA:
39.6		 1vhwA-6g7xA:
undetectable
1vhwD-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_B_ADNB252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		5 / 9 MET A  64
ARG A  87
GLY A  92
MET A 180
GLU A 181
 None
PO4  A 304 ( 4.4A)
IMD  A 302 ( 4.2A)
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
 0.49A 1vhwB-6g7xA:
39.9
1vhwF-6g7xA:
39.3		 1vhwB-6g7xA:
undetectable
1vhwF-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		6 / 11 ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
ILE A  94
 PO4  A 304 ( 4.4A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
 1.48A 1vhwC-6g7xA:
39.7
1vhwE-6g7xA:
39.6		 1vhwC-6g7xA:
undetectable
1vhwE-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		6 / 11 MET A  64
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
 None
PO4  A 304 ( 4.4A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
 0.47A 1vhwC-6g7xA:
39.7
1vhwE-6g7xA:
39.6		 1vhwC-6g7xA:
undetectable
1vhwE-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		6 / 11 ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
ILE A  94
 PO4  A 304 ( 4.4A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
 1.46A 1vhwA-6g7xA:
39.8
1vhwD-6g7xA:
39.6		 1vhwA-6g7xA:
undetectable
1vhwD-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		6 / 11 MET A  64
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
 None
PO4  A 304 ( 4.4A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
 0.47A 1vhwA-6g7xA:
39.8
1vhwD-6g7xA:
39.6		 1vhwA-6g7xA:
undetectable
1vhwD-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		6 / 11 ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
ILE A  94
 PO4  A 304 ( 4.4A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
 1.42A 1vhwC-6g7xA:
39.7
1vhwE-6g7xA:
39.6		 1vhwC-6g7xA:
undetectable
1vhwE-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		6 / 11 MET A  64
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
 None
PO4  A 304 ( 4.4A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
 0.46A 1vhwC-6g7xA:
39.7
1vhwE-6g7xA:
39.6		 1vhwC-6g7xA:
undetectable
1vhwE-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_F_ADNF252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		6 / 10 MET A  64
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
 None
PO4  A 304 ( 4.4A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
 0.47A 1vhwB-6g7xA:
39.9
1vhwF-6g7xA:
39.3		 1vhwB-6g7xA:
undetectable
1vhwF-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		8 / 10 MET A  64
ARG A  87
THR A  90
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 None
PO4  A 304 ( 4.4A)
PO4  A 304 (-2.8A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
 0.44A 1z35A-6g7xA:
37.5		 1z35A-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z37_A_ADNA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		8 / 9 MET A  64
ARG A  87
THR A  90
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 None
PO4  A 304 ( 4.4A)
PO4  A 304 (-2.8A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
 0.46A 1z37A-6g7xA:
37.6		 1z37A-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AC7_A_ADNA1216_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		7 / 11 MET A  64
ARG A  87
THR A  90
GLY A  92
GLU A 179
MET A 180
GLU A 181
 None
PO4  A 304 ( 4.4A)
PO4  A 304 (-2.8A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
 0.48A 2ac7A-6g7xA:
36.3
2ac7B-6g7xA:
36.4		 2ac7A-6g7xA:
undetectable
2ac7B-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AC7_B_ADNB1215_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		7 / 11 MET A  64
ARG A  87
THR A  90
GLY A  92
GLU A 179
MET A 180
GLU A 181
 None
PO4  A 304 ( 4.4A)
PO4  A 304 (-2.8A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
 0.49A 2ac7A-6g7xA:
36.3
2ac7B-6g7xA:
36.4		 2ac7A-6g7xA:
undetectable
2ac7B-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBN_A_CAMA442_0
(CYTOCHROME P450-CAM)		 6g7x -
(-) 		4 / 7 PHE A  12
TYR A  80
VAL A  42
ASP A  11
 None
 1.01A 2qbnA-6g7xA:
undetectable		 2qbnA-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBO_A_CAMA442_0
(CYTOCHROME P450-CAM)		 6g7x -
(-) 		5 / 10 PHE A  12
TYR A  80
VAL A  42
ASP A  11
ILE A  39
 None
 1.31A 2qboA-6g7xA:
undetectable		 2qboA-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_E_TOPE1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 6g7x -
(-) 		4 / 8 ILE A 146
ALA A 137
LEU A  86
ILE A 103
 None
 0.76A 2w9sE-6g7xA:
undetectable		 2w9sE-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 6g7x -
(-) 		5 / 12 ILE A  28
PHE A 221
ALA A 106
ILE A  88
MET A 231
 None
 1.33A 2xkwB-6g7xA:
undetectable		 2xkwB-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 6g7x -
(-) 		5 / 12 ILE A  28
PHE A 221
LEU A 197
ILE A  88
MET A 231
 None
 1.21A 2xkwB-6g7xA:
undetectable		 2xkwB-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)		 6g7x -
(-) 		5 / 10 THR A  90
GLY A  92
PHE A 159
GLU A 179
MET A 180
 PO4  A 304 (-2.8A)
IMD  A 302 ( 4.2A)
IMD  A 302 (-4.4A)
None
IMD  A 302 (-4.6A)
 0.42A 3kvrA-6g7xA:
19.5		 3kvrA-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 6g7x -
(-) 		5 / 10 THR A  90
GLY A  92
PHE A 159
GLU A 179
MET A 180
 PO4  A 304 (-2.8A)
IMD  A 302 ( 4.2A)
IMD  A 302 (-4.4A)
None
IMD  A 302 (-4.6A)
 0.43A 3kvrB-6g7xA:
23.7		 3kvrB-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_A_ADNA251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		5 / 9 MET A  64
ARG A  87
GLU A 179
MET A 180
GLU A 181
 None
PO4  A 304 ( 4.4A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
 0.36A 3u40A-6g7xA:
37.0
3u40F-6g7xA:
18.4		 3u40A-6g7xA:
undetectable
3u40F-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_B_ADNB251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		5 / 10 MET A  64
ARG A  87
GLU A 179
MET A 180
GLU A 181
 None
PO4  A 304 ( 4.4A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
 0.33A 3u40B-6g7xA:
36.7
3u40C-6g7xA:
22.2		 3u40B-6g7xA:
undetectable
3u40C-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_C_ADNC251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		6 / 12 MET A  64
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
 None
PO4  A 304 ( 4.4A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
 0.25A 3u40B-6g7xA:
36.7
3u40C-6g7xA:
22.2		 3u40B-6g7xA:
undetectable
3u40C-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_D_ADND251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		6 / 11 MET A  64
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
 None
PO4  A 304 ( 4.4A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
 0.28A 3u40D-6g7xA:
36.8
3u40E-6g7xA:
35.9		 3u40D-6g7xA:
undetectable
3u40E-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_E_ADNE251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		6 / 12 MET A  64
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
 None
PO4  A 304 ( 4.4A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
 0.30A 3u40D-6g7xA:
36.8
3u40E-6g7xA:
35.9		 3u40D-6g7xA:
undetectable
3u40E-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_F_ADNF251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6g7x -
(-) 		5 / 10 MET A  64
ARG A  87
GLU A 179
MET A 180
GLU A 181
 None
PO4  A 304 ( 4.4A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
 0.29A 3u40A-6g7xA:
37.0
3u40F-6g7xA:
18.4		 3u40A-6g7xA:
undetectable
3u40F-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 6g7x -
(-) 		6 / 11 ARG A  87
THR A  90
GLY A  92
GLU A 179
GLU A 181
ILE A  94
 PO4  A 304 ( 4.4A)
PO4  A 304 (-2.8A)
IMD  A 302 ( 4.2A)
None
PO4  A 304 ( 4.7A)
None
 1.39A 3uawA-6g7xA:
38.0		 3uawA-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 6g7x -
(-) 		8 / 11 MET A  64
ARG A  87
THR A  90
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 None
PO4  A 304 ( 4.4A)
PO4  A 304 (-2.8A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
 0.60A 3uawA-6g7xA:
38.0		 3uawA-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 6g7x -
(-) 		6 / 10 ARG A  87
THR A  90
GLY A  92
GLU A 179
GLU A 181
ILE A  94
 PO4  A 304 ( 4.4A)
PO4  A 304 (-2.8A)
IMD  A 302 ( 4.2A)
None
PO4  A 304 ( 4.7A)
None
 1.40A 3uayA-6g7xA:
38.2		 3uayA-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 6g7x -
(-) 		7 / 10 MET A  64
ARG A  87
THR A  90
GLY A  92
GLU A 179
MET A 180
GLU A 181
 None
PO4  A 304 ( 4.4A)
PO4  A 304 (-2.8A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
 0.45A 3uayA-6g7xA:
38.2		 3uayA-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 6g7x -
(-) 		8 / 11 MET A  64
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
ASP A 204
 None
PO4  A 304 ( 4.4A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
None
 0.87A 4d9hA-6g7xA:
37.7		 4d9hA-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA6_A_GA2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 6g7x -
(-) 		5 / 9 MET A  64
GLY A  92
MET A 180
GLU A 181
ASP A 204
 None
IMD  A 302 ( 4.2A)
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
 0.99A 4da6A-6g7xA:
37.3		 4da6A-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA6_A_GA2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 6g7x -
(-) 		5 / 9 MET A  64
MET A 180
GLU A 181
SER A 203
ASP A 204
 None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
None
 1.16A 4da6A-6g7xA:
37.3		 4da6A-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 6g7x -
(-) 		7 / 10 MET A  64
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 None
PO4  A 304 ( 4.4A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
 0.64A 4da7A-6g7xA:
37.8		 4da7A-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 6g7x -
(-) 		8 / 11 MET A  64
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
ASP A 204
 None
PO4  A 304 ( 4.4A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
None
 0.98A 4danA-6g7xA:
37.2		 4danA-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 6g7x -
(-) 		7 / 12 ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
ASP A 204
 PO4  A 304 ( 4.4A)
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
None
 1.01A 4danA-6g7xA:
37.2
4danB-6g7xA:
37.3		 4danA-6g7xA:
undetectable
4danB-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 6g7x -
(-) 		5 / 9 MET A  64
ARG A  87
GLY A  92
MET A 180
GLU A 181
 None
PO4  A 304 ( 4.4A)
IMD  A 302 ( 4.2A)
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
 0.49A 5i3cA-6g7xA:
38.4		 5i3cA-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 6g7x -
(-) 		5 / 10 MET A  64
GLY A  92
GLU A 179
MET A 180
GLU A 181
 None
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
 0.33A 5i3cB-6g7xA:
38.8		 5i3cB-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 6g7x -
(-) 		6 / 11 MET A  64
GLY A  92
GLU A 179
MET A 180
GLU A 181
ASP A 204
 None
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
 0.77A 5i3cC-6g7xA:
38.5		 5i3cC-6g7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 6g7x -
(-) 		6 / 11 MET A  64
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 None
IMD  A 302 ( 4.2A)
None
IMD  A 302 (-4.6A)
PO4  A 304 ( 4.7A)
None
 0.44A 5i3cC-6g7xA:
38.5		 5i3cC-6g7xA:
undetectable