SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6g94'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OWX_A_XRAA233_2 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	6g94	PROBABLE NI/FE-HYDROGENASE 1 B-TYPE CYTOCHROME SUBUNIT (Escherichia coli)	4 / 5	VAL A 69 PHE A 148 ILE A 144 PHE A 163	None HEM A 301 (-3.7A) HEM A 301 ( 4.4A) None	1.02A	3owxB-6g94A: undetectable	3owxB-6g94A: 18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FUB_A_ACTA311_0 (UROKINASE-TYPE PLASMINOGEN ACTIVATOR)	6g94	PROBABLE NI/FE-HYDROGENASE 1 B-TYPE CYTOCHROME SUBUNIT (Escherichia coli)	3 / 3	TYR A 136 ARG A 77 HIS A 22	None	1.20A	4fubA-6g94A: undetectable	4fubA-6g94A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QOG_A_ML1A302_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	6g94	PROBABLE NI/FE-HYDROGENASE 1 B-TYPE CYTOCHROME SUBUNIT (Escherichia coli)	4 / 8	PHE A 148 ILE A 144 PHE A 163 ILE A 78	HEM A 301 (-3.7A) HEM A 301 ( 4.4A) None None	0.87A	4qogA-6g94A: undetectable 4qogB-6g94A: undetectable	4qogA-6g94A: 18.06 4qogB-6g94A: 18.06

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3OWX_A_XRAA233_2","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE];RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","6g94","PROBABLE NI\/FE-HYDROGENASE 1 B-TYPE CYTOCHROME SUBUNIT","Escherichia coli",4,"VAL A  69;PHE A 148;ILE A 144;PHE A 163","None;HEM A 301 (-3.7A);HEM A 301 ( 4.4A);None","1.02A","3owxB-6g94A:undetectable","3owxB-6g94A:18.06"],["4FUB_A_ACTA311_0","UROKINASE-TYPE PLASMINOGEN ACTIVATOR","6g94","PROBABLE NI\/FE-HYDROGENASE 1 B-TYPE CYTOCHROME SUBUNIT","Escherichia coli",3,"TYR A 136;ARG A  77;HIS A  22","None","1.20A","4fubA-6g94A:undetectable","4fubA-6g94A:undetectable"],["4QOG_A_ML1A302_1","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE];RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","6g94","PROBABLE NI\/FE-HYDROGENASE 1 B-TYPE CYTOCHROME SUBUNIT","Escherichia coli",4,"PHE A 148;ILE A 144;PHE A 163;ILE A  78","HEM A 301 (-3.7A);HEM A 301 ( 4.4A);None;None","0.87A","4qogA-6g94A:undetectable;4qogB-6g94A:undetectable","4qogA-6g94A:18.06;4qogB-6g94A:18.06"]]