SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6g96'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MX1_B_THAB2_1 (LIVER CARBOXYLESTERASE I)	6g96	ACETYLTRANSFERASE (Salmonella enterica)	5 / 11	VAL B 64 LEU B 111 LEU B 92 LEU B 169 LEU B 112	None None ACO B 201 (-4.8A) None None	1.17A	1mx1B-6g96B: undetectable	1mx1B-6g96B: 9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SG9_B_SAMB302_1 (HEMK PROTEIN)	6g96	ACETYLTRANSFERASE (Salmonella enterica)	3 / 3	ASP B 98 PHE B 61 ASN B 16	None	0.82A	1sg9B-6g96B: undetectable	1sg9B-6g96B: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XDK_A_9CRA500_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	6g96	ACETYLTRANSFERASE (Salmonella enterica)	5 / 12	TRP B 142 LEU B 169 ALA B 168 VAL B 64 LEU B 95	ACO B 201 ( 3.9A) None None None ACO B 201 (-4.6A)	1.04A	1xdkA-6g96B: undetectable	1xdkA-6g96B: 16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XDK_E_9CRE1500_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	6g96	ACETYLTRANSFERASE (Salmonella enterica)	5 / 12	TRP B 142 LEU B 169 ALA B 168 VAL B 64 LEU B 95	ACO B 201 ( 3.9A) None None None ACO B 201 (-4.6A)	1.04A	1xdkE-6g96B: undetectable	1xdkE-6g96B: 16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AX9_B_SALB1340_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	6g96	ACETYLTRANSFERASE (Salmonella enterica)	4 / 8	LEU B 160 SER B 161 ALA B 168 ALA B 167	None	0.90A	3ax9B-6g96B: undetectable	3ax9B-6g96B: 4.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QXV_D_MTXD2000_2 (ANTI-METHOTREXATE CDR1-4 GRAFT VHH)	6g96	ACETYLTRANSFERASE (Salmonella enterica)	3 / 3	LEU B 110 ARG B 57 ASN B 28	None	0.73A	3qxvD-6g96B: undetectable	3qxvD-6g96B: 19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FHR_A_SAMA303_0 (CATECHOL O-METHYLTRANSFERASE)	6g96	ACETYLTRANSFERASE (Salmonella enterica)	5 / 12	GLY B 60 TYR B 62 GLN B 104 HIS B 59 TRP B 6	None	1.17A	5fhrA-6g96B: undetectable	5fhrA-6g96B: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5I3B_B_HQEB303_1 (TYROSINASE)	6g96	ACETYLTRANSFERASE (Salmonella enterica)	4 / 5	HIS B 15 HIS B 7 VAL B 48 ALA B 9	None	1.31A	5i3bB-6g96B: undetectable	5i3bB-6g96B: 14.29

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1MX1_B_THAB2_1","LIVER CARBOXYLESTERASE I","6g96","ACETYLTRANSFERASE","Salmonella enterica",5,"VAL B  64;LEU B 111;LEU B  92;LEU B 169;LEU B 112","None;None;ACO B 201 (-4.8A);None;None","1.17A","1mx1B-6g96B:undetectable","1mx1B-6g96B:9.35"],["1SG9_B_SAMB302_1","HEMK PROTEIN","6g96","ACETYLTRANSFERASE","Salmonella enterica",3,"ASP B  98;PHE B  61;ASN B  16","None","0.82A","1sg9B-6g96B:undetectable","1sg9B-6g96B:undetectable"],["1XDK_A_9CRA500_1","RETINOIC ACID RECEPTOR RXR-ALPHA","6g96","ACETYLTRANSFERASE","Salmonella enterica",5,"TRP B 142;LEU B 169;ALA B 168;VAL B  64;LEU B  95","ACO B 201 ( 3.9A);None;None;None;ACO B 201 (-4.6A)","1.04A","1xdkA-6g96B:undetectable","1xdkA-6g96B:16.26"],["1XDK_E_9CRE1500_1","RETINOIC ACID RECEPTOR RXR-ALPHA","6g96","ACETYLTRANSFERASE","Salmonella enterica",5,"TRP B 142;LEU B 169;ALA B 168;VAL B  64;LEU B  95","ACO B 201 ( 3.9A);None;None;None;ACO B 201 (-4.6A)","1.04A","1xdkE-6g96B:undetectable","1xdkE-6g96B:16.26"],["3AX9_B_SALB1340_1","XANTHINE DEHYDROGENASE\/OXIDASE","6g96","ACETYLTRANSFERASE","Salmonella enterica",4,"LEU B 160;SER B 161;ALA B 168;ALA B 167","None","0.90A","3ax9B-6g96B:undetectable","3ax9B-6g96B:4.93"],["3QXV_D_MTXD2000_2","ANTI-METHOTREXATE CDR1-4 GRAFT VHH","6g96","ACETYLTRANSFERASE","Salmonella enterica",3,"LEU B 110;ARG B  57;ASN B  28","None","0.73A","3qxvD-6g96B:undetectable","3qxvD-6g96B:19.38"],["5FHR_A_SAMA303_0","CATECHOL O-METHYLTRANSFERASE","6g96","ACETYLTRANSFERASE","Salmonella enterica",5,"GLY B  60;TYR B  62;GLN B 104;HIS B  59;TRP B   6","None","1.17A","5fhrA-6g96B:undetectable","5fhrA-6g96B:undetectable"],["5I3B_B_HQEB303_1","TYROSINASE","6g96","ACETYLTRANSFERASE","Salmonella enterica",4,"HIS B  15;HIS B   7;VAL B  48;ALA B   9","None","1.31A","5i3bB-6g96B:undetectable","5i3bB-6g96B:14.29"]]