SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6gbg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA734_1
(ALPHA AMYLASE)		 6gbg OUTER MEMBRANE
PROTEIN
(Helicobacter
pylori) 		4 / 6 ASN A 113
HIS A 142
TYR A 144
GLY A 133
 None
 1.26A 1mxdA-6gbgA:
undetectable		 1mxdA-6gbgA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA734_1
(ALPHA AMYLASE)		 6gbg OUTER MEMBRANE
PROTEIN
(Helicobacter
pylori) 		4 / 6 ASN A 113
HIS A 142
TYR A 144
GLY A 146
 None
 0.94A 1mxdA-6gbgA:
undetectable		 1mxdA-6gbgA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA444_1
(ALPHA AMYLASE)		 6gbg OUTER MEMBRANE
PROTEIN
(Helicobacter
pylori) 		4 / 7 ASN A 113
HIS A 142
TYR A 144
GLY A 133
 None
 1.23A 1mxgA-6gbgA:
undetectable		 1mxgA-6gbgA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA444_1
(ALPHA AMYLASE)		 6gbg OUTER MEMBRANE
PROTEIN
(Helicobacter
pylori) 		4 / 7 ASN A 113
HIS A 142
TYR A 144
GLY A 146
 None
 0.97A 1mxgA-6gbgA:
undetectable		 1mxgA-6gbgA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 6gbg OUTER MEMBRANE
PROTEIN
(Helicobacter
pylori) 		4 / 7 PHE A 277
THR A 272
LEU A 241
VAL A 101
 None
 1.04A 1yrcA-6gbgA:
undetectable		 1yrcA-6gbgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 6gbg OUTER MEMBRANE
PROTEIN
(Helicobacter
pylori) 		4 / 6 PHE A 277
THR A 272
LEU A 241
VAL A 101
 None
 1.03A 2feuA-6gbgA:
undetectable		 2feuA-6gbgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 6gbg OUTER MEMBRANE
PROTEIN
(Helicobacter
pylori) 		4 / 6 PHE A 277
THR A 272
LEU A 241
VAL A 101
 None
 1.06A 2zuiA-6gbgA:
undetectable		 2zuiA-6gbgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 6gbg OUTER MEMBRANE
PROTEIN
(Helicobacter
pylori) 		4 / 7 PHE A 277
THR A 272
LEU A 241
VAL A 101
 None
 1.03A 2zwtA-6gbgA:
undetectable		 2zwtA-6gbgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 6gbg OUTER MEMBRANE
PROTEIN
(Helicobacter
pylori) 		4 / 7 PHE A 277
THR A 272
LEU A 241
VAL A 101
 None
 1.03A 2zwuA-6gbgA:
undetectable		 2zwuA-6gbgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 6gbg OUTER MEMBRANE
PROTEIN
(Helicobacter
pylori) 		4 / 7 PHE A 277
THR A 272
LEU A 241
VAL A 101
 None
 1.02A 3fwfB-6gbgA:
undetectable		 3fwfB-6gbgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 6gbg OUTER MEMBRANE
PROTEIN
(Helicobacter
pylori) 		4 / 7 PHE A 277
THR A 272
LEU A 241
VAL A 101
 None
 1.02A 3fwiA-6gbgA:
undetectable		 3fwiA-6gbgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 6gbg OUTER MEMBRANE
PROTEIN
(Helicobacter
pylori) 		4 / 7 PHE A 277
THR A 272
LEU A 241
VAL A 101
 None
 1.04A 3fwjA-6gbgA:
undetectable		 3fwjA-6gbgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 6gbg OUTER MEMBRANE
PROTEIN
(Helicobacter
pylori) 		4 / 7 PHE A 277
THR A 272
LEU A 241
VAL A 101
 None
 1.02A 3l63A-6gbgA:
undetectable		 3l63A-6gbgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 6gbg OUTER MEMBRANE
PROTEIN
(Helicobacter
pylori) 		4 / 7 PHE A 277
THR A 272
LEU A 241
VAL A 101
 None
 1.05A 3wrjA-6gbgA:
undetectable		 3wrjA-6gbgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 6gbg OUTER MEMBRANE
PROTEIN
(Helicobacter
pylori) 		4 / 7 PHE A 277
THR A 272
LEU A 241
VAL A 101
 None
 1.02A 3wrlE-6gbgA:
undetectable		 3wrlE-6gbgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 6gbg OUTER MEMBRANE
PROTEIN
(Helicobacter
pylori) 		4 / 7 PHE A 277
THR A 272
LEU A 241
VAL A 101
 None
 1.03A 3wrmA-6gbgA:
undetectable		 3wrmA-6gbgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZTV_A_ADNA1600_1
(NAD NUCLEOTIDASE)		 6gbg OUTER MEMBRANE
PROTEIN
(Helicobacter
pylori) 		5 / 9 ASN A 148
GLY A 133
GLY A 134
SER A 157
GLY A 104
 None
 0.97A 3ztvA-6gbgA:
undetectable		 3ztvA-6gbgA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_A_ESTA2000_1
(ESTROGEN RECEPTOR)		 6gbg OUTER MEMBRANE
PROTEIN
(Helicobacter
pylori) 		5 / 12 LEU A  84
ALA A  82
LEU A 394
GLY A  73
LEU A 185
 None
None
None
BR  A 503 ( 4.0A)
None
 0.95A 4pxmA-6gbgA:
undetectable		 4pxmA-6gbgA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_A_ESTA2000_1
(ESTROGEN RECEPTOR)		 6gbg OUTER MEMBRANE
PROTEIN
(Helicobacter
pylori) 		5 / 12 LEU A  84
LEU A  85
ALA A  82
GLY A  73
LEU A 185
 None
None
None
BR  A 503 ( 4.0A)
None
 0.81A 4pxmA-6gbgA:
undetectable		 4pxmA-6gbgA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA503_1
(PENTALENIC ACID
SYNTHASE)		 6gbg OUTER MEMBRANE
PROTEIN
(Helicobacter
pylori) 		4 / 7 LEU A 182
ALA A 287
LEU A 224
ILE A 290
 None
 0.69A 4ubsA-6gbgA:
1.9		 4ubsA-6gbgA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_D_LOCD502_1
(TUBULIN BETA CHAIN)		 6gbg OUTER MEMBRANE
PROTEIN
(Helicobacter
pylori) 		5 / 12 LEU A 173
LEU A 182
ALA A 287
ALA A 220
ILE A 284
 None
 1.10A 4x1iD-6gbgA:
undetectable		 4x1iD-6gbgA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_2
(TUBULIN BETA CHAIN)		 6gbg OUTER MEMBRANE
PROTEIN
(Helicobacter
pylori) 		5 / 12 LEU A 173
LEU A 182
ALA A 287
ALA A 220
ILE A 284
 None
 1.07A 4x1kD-6gbgA:
undetectable		 4x1kD-6gbgA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_A_SALA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6gbg OUTER MEMBRANE
PROTEIN
(Helicobacter
pylori) 		4 / 8 VAL A 101
LEU A 241
LEU A 355
TRP A 260
 None
 0.73A 5f1aA-6gbgA:
undetectable		 5f1aA-6gbgA:
8.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 6gbg OUTER MEMBRANE
PROTEIN
(Helicobacter
pylori) 		3 / 3 ALA A  79
GLN A 333
THR A 294
 None
 0.76A 5n0oA-6gbgA:
undetectable		 5n0oA-6gbgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 6gbg OUTER MEMBRANE
PROTEIN
(Helicobacter
pylori) 		4 / 5 TYR A 237
SER A 157
ALA A 152
THR A 107
 None
 1.19A 5n0wB-6gbgA:
undetectable		 5n0wB-6gbgA:
undetectable