SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6gbh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 6gbh HOPQ
(Helicobacter
pylori) 		4 / 5 ILE C  64
SER C 329
LEU C  67
ASN C  68
 None
 1.19A 1y0xX-6gbhC:
undetectable		 1y0xX-6gbhC:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 6gbh HOPQ
(Helicobacter
pylori) 		5 / 12 GLY C 109
ASN C 148
ILE C 152
GLY C 140
ASN C 115
 None
 1.12A 3ps9A-6gbhC:
undetectable		 3ps9A-6gbhC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_A_LLTA261_1
(DEOXYCYTIDINE KINASE)		 6gbh HOPQ
(Helicobacter
pylori) 		5 / 10 GLU C 357
VAL C 380
LEU C  89
MET C 281
GLU C 388
 None
 1.23A 3qeoA-6gbhC:
undetectable		 3qeoA-6gbhC:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7V_A_SAMA992_0
(METHYLORNITHINE
SYNTHASE PYLB)		 6gbh HOPQ
(Helicobacter
pylori) 		5 / 12 THR C 372
GLY C 374
GLY C 376
TYR C 162
LEU C 158
 None
 1.10A 3t7vA-6gbhC:
undetectable		 3t7vA-6gbhC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6gbh HOPQ
(Helicobacter
pylori) 		5 / 11 ALA C  59
THR C  58
ALA C  57
GLY C  65
ALA C  63
 None
 0.86A 4qvlK-6gbhC:
undetectable
4qvlL-6gbhC:
undetectable		 4qvlK-6gbhC:
15.61
4qvlL-6gbhC:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6gbh HOPQ
(Helicobacter
pylori) 		5 / 11 ALA C  59
THR C  58
ALA C  57
GLY C  65
ALA C  63
 None
 0.86A 4qvlY-6gbhC:
undetectable
4qvlZ-6gbhC:
undetectable		 4qvlY-6gbhC:
15.61
4qvlZ-6gbhC:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6gbh HOPQ
(Helicobacter
pylori) 		5 / 9 ALA C  59
THR C  58
ALA C  57
GLY C  65
ALA C  63
 None
 0.86A 4qvmK-6gbhC:
undetectable
4qvmL-6gbhC:
undetectable		 4qvmK-6gbhC:
15.38
4qvmL-6gbhC:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6gbh HOPQ
(Helicobacter
pylori) 		5 / 10 ALA C  59
THR C  58
ALA C  57
GLY C  65
ALA C  63
 None
 0.86A 4qvmY-6gbhC:
undetectable
4qvmZ-6gbhC:
undetectable		 4qvmY-6gbhC:
15.38
4qvmZ-6gbhC:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6gbh HOPQ
(Helicobacter
pylori) 		5 / 9 ALA C  59
THR C  58
ALA C  57
GLY C  65
ALA C  63
 None
 1.23A 4qvnK-6gbhC:
undetectable
4qvnL-6gbhC:
undetectable		 4qvnK-6gbhC:
15.61
4qvnL-6gbhC:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6gbh HOPQ
(Helicobacter
pylori) 		5 / 9 ALA C  59
THR C  58
ALA C  57
GLY C  65
ALA C  63
 None
 1.22A 4qvnY-6gbhC:
undetectable
4qvnZ-6gbhC:
undetectable		 4qvnY-6gbhC:
15.61
4qvnZ-6gbhC:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6gbh HOPQ
(Helicobacter
pylori) 		5 / 10 ALA C  59
THR C  58
ALA C  57
GLY C  65
ALA C  63
 None
 0.87A 4qvpK-6gbhC:
undetectable
4qvpL-6gbhC:
undetectable		 4qvpK-6gbhC:
15.61
4qvpL-6gbhC:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6gbh HOPQ
(Helicobacter
pylori) 		5 / 10 ALA C  59
THR C  58
ALA C  57
GLY C  65
ALA C  63
 None
 0.87A 4qvpY-6gbhC:
undetectable
4qvpZ-6gbhC:
undetectable		 4qvpY-6gbhC:
15.61
4qvpZ-6gbhC:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6gbh HOPQ
(Helicobacter
pylori) 		5 / 11 ALA C  59
THR C  58
ALA C  57
GLY C  65
ALA C  63
 None
 0.85A 4qw1K-6gbhC:
undetectable
4qw1L-6gbhC:
undetectable		 4qw1K-6gbhC:
15.12
4qw1L-6gbhC:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6gbh HOPQ
(Helicobacter
pylori) 		5 / 10 ALA C  59
THR C  58
ALA C  57
GLY C  65
ALA C  63
 None
 0.85A 4qw1Y-6gbhC:
undetectable
4qw1Z-6gbhC:
undetectable		 4qw1Y-6gbhC:
15.12
4qw1Z-6gbhC:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6gbh HOPQ
(Helicobacter
pylori) 		5 / 10 ALA C  59
THR C  58
ALA C  57
GLY C  65
ALA C  63
 None
 0.86A 4qw3K-6gbhC:
undetectable
4qw3L-6gbhC:
undetectable		 4qw3K-6gbhC:
15.61
4qw3L-6gbhC:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6gbh HOPQ
(Helicobacter
pylori) 		5 / 10 ALA C  59
THR C  58
ALA C  57
GLY C  65
ALA C  63
 None
 0.86A 4qw3Y-6gbhC:
undetectable
4qw3Z-6gbhC:
undetectable		 4qw3Y-6gbhC:
15.61
4qw3Z-6gbhC:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_B_STRB601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 6gbh HOPQ
(Helicobacter
pylori) 		5 / 9 ALA C 227
ILE C 347
ALA C  90
ILE C 165
VAL C 380
 None
 0.92A 4r21B-6gbhC:
undetectable		 4r21B-6gbhC:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 6gbh HOPQ
(Helicobacter
pylori) 		5 / 12 GLY C 136
ASN C 117
LEU C 150
ALA C 156
THR C 157
 None
 1.10A 4uckB-6gbhC:
undetectable		 4uckB-6gbhC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_1
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 6gbh HOPQ
(Helicobacter
pylori) 		5 / 12 ALA C  90
VAL C 340
GLN C 286
GLN C 290
GLU C 291
 None
 1.35A 4zj8A-6gbhC:
3.8		 4zj8A-6gbhC:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6gbh HOPQ
(Helicobacter
pylori) 		5 / 11 ALA C  59
THR C  58
ALA C  57
GLY C  65
ALA C  63
 None
 0.86A 5bxnK-6gbhC:
undetectable
5bxnL-6gbhC:
undetectable		 5bxnK-6gbhC:
15.61
5bxnL-6gbhC:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6gbh HOPQ
(Helicobacter
pylori) 		5 / 11 ALA C  59
THR C  58
ALA C  57
GLY C  65
ALA C  63
 None
 0.86A 5bxnY-6gbhC:
undetectable
5bxnZ-6gbhC:
undetectable		 5bxnY-6gbhC:
15.61
5bxnZ-6gbhC:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6gbh HOPQ
(Helicobacter
pylori) 		5 / 9 ALA C  59
THR C  58
ALA C  57
GLY C  65
ALA C  63
 None
 0.85A 5d0xK-6gbhC:
undetectable
5d0xL-6gbhC:
undetectable		 5d0xK-6gbhC:
15.61
5d0xL-6gbhC:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6gbh HOPQ
(Helicobacter
pylori) 		5 / 9 ALA C  59
THR C  58
ALA C  57
GLY C  65
ALA C  63
 None
 0.86A 5d0xY-6gbhC:
undetectable
5d0xZ-6gbhC:
undetectable		 5d0xY-6gbhC:
15.61
5d0xZ-6gbhC:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_A_SALA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6gbh HOPQ
(Helicobacter
pylori) 		4 / 8 VAL C 105
LEU C 241
LEU C 352
TRP C 259
 None
 0.74A 5f1aA-6gbhC:
undetectable		 5f1aA-6gbhC:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 6gbh HOPQ
(Helicobacter
pylori) 		3 / 3 ALA C  83
GLN C 330
THR C 292
 None
 0.70A 5n0oA-6gbhC:
undetectable		 5n0oA-6gbhC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 6gbh HOPQ
(Helicobacter
pylori) 		4 / 4 SER C  81
ALA C  83
GLN C 330
THR C 292
 None
 1.05A 5n0xA-6gbhC:
undetectable		 5n0xA-6gbhC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 6gbh HOPQ
(Helicobacter
pylori) 		4 / 5 SER C  81
ALA C  83
GLN C 330
THR C 292
 None
 1.05A 5n4iA-6gbhC:
undetectable		 5n4iA-6gbhC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9A_A_AR3A201_1
(PEPTIDYL-TRNA
HYDROLASE)		 6gbh HOPQ
(Helicobacter
pylori) 		4 / 6 ALA C 285
GLN C 286
GLN C 221
ASP C 219
 None
 1.40A 5y9aA-6gbhC:
undetectable		 5y9aA-6gbhC:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6gbh HOPQ
(Helicobacter
pylori) 		5 / 11 ALA C  59
THR C  58
ALA C  57
GLY C  65
ALA C  63
 None
 0.88A 6hwdK-6gbhC:
undetectable
6hwdL-6gbhC:
undetectable		 6hwdK-6gbhC:
15.85
6hwdL-6gbhC:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6gbh HOPQ
(Helicobacter
pylori) 		5 / 11 ALA C  59
THR C  58
ALA C  57
GLY C  65
ALA C  63
 None
 0.88A 6hwdY-6gbhC:
undetectable
6hwdZ-6gbhC:
undetectable		 6hwdY-6gbhC:
15.85
6hwdZ-6gbhC:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_1
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 6gbh HOPQ
(Helicobacter
pylori) 		3 / 3 ASP C 236
SER C 276
SER C 279
 None
 0.82A 6mxtA-6gbhC:
3.3		 6mxtA-6gbhC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QXS_B_FOZB403_0
(THYMIDYLATE SYNTHASE)		 6gbh HOPQ
(Helicobacter
pylori) 		5 / 12 LEU C 158
ILE C 230
LEU C  97
GLY C  96
ILE C 278
 None
 1.04A 6qxsB-6gbhC:
undetectable		 6qxsB-6gbhC:
undetectable