SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6gbv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_1
(BLUE-LIGHT
PHOTORECEPTOR)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		5 / 12 ASN A  47
ASN A  71
CYH A  72
ASN A 104
ILE A  88
 FMN  A 500 ( 3.7A)
FMN  A 500 ( 3.2A)
FMN  A 500 (-3.7A)
FMN  A 500 (-3.0A)
FMN  A 500 (-4.1A)
 1.47A 4kukA-6gbvA:
25.8		 4kukA-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_1
(BLUE-LIGHT
PHOTORECEPTOR)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		7 / 12 VAL A  38
SER A  40
ASN A  47
ASN A  71
ARG A  73
GLN A  76
ASN A 104
 FMN  A 500 (-4.8A)
FMN  A 500 (-3.1A)
FMN  A 500 ( 3.7A)
FMN  A 500 ( 3.2A)
FMN  A 500 (-4.5A)
FMN  A 500 (-4.2A)
FMN  A 500 (-3.0A)
 0.84A 4kukA-6gbvA:
25.8		 4kukA-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_1
(BLUE-LIGHT
PHOTORECEPTOR)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		11 / 12 VAL A  38
SER A  40
ASN A  47
ASN A  71
CYH A  72
ARG A  73
ASN A 104
ASN A 114
LEU A 116
ILE A 118
GLN A 135
 FMN  A 500 (-4.8A)
FMN  A 500 (-3.1A)
FMN  A 500 ( 3.7A)
FMN  A 500 ( 3.2A)
FMN  A 500 (-3.7A)
FMN  A 500 (-4.5A)
FMN  A 500 (-3.0A)
FMN  A 500 (-4.0A)
FMN  A 500 (-4.1A)
None
FMN  A 500 (-3.8A)
 0.66A 4kukA-6gbvA:
25.8		 4kukA-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_1
(BLUE-LIGHT
PHOTORECEPTOR)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		6 / 12 VAL A  38
SER A  40
ASN A  47
ASN A  71
CYH A  72
ASN A 104
 FMN  A 500 (-4.8A)
FMN  A 500 (-3.1A)
FMN  A 500 ( 3.7A)
FMN  A 500 ( 3.2A)
FMN  A 500 (-3.7A)
FMN  A 500 (-3.0A)
 1.12A 4kukA-6gbvA:
25.8		 4kukA-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_2
(BLUE-LIGHT
PHOTORECEPTOR)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		8 / 9 LEU A  75
VAL A  85
ILE A  88
ARG A  89
LEU A  92
ILE A 102
PHE A 131
GLY A 133
 FMN  A 500 (-4.0A)
FMN  A 500 (-4.3A)
FMN  A 500 (-4.1A)
None
FMN  A 500 (-4.6A)
FMN  A 500 ( 4.3A)
FMN  A 500 (-4.8A)
FMN  A 500 (-3.9A)
 0.29A 4kukA-6gbvA:
25.8		 4kukA-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUO_A_RBFA500_1
(BLUE-LIGHT
PHOTORECEPTOR)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		5 / 12 VAL A  38
ASN A  71
ASN A 114
LEU A 116
GLN A 135
 FMN  A 500 (-4.8A)
FMN  A 500 ( 3.2A)
FMN  A 500 (-4.0A)
FMN  A 500 (-4.1A)
FMN  A 500 (-3.8A)
 1.17A 4kuoA-6gbvA:
23.6		 4kuoA-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUO_A_RBFA500_1
(BLUE-LIGHT
PHOTORECEPTOR)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		7 / 12 VAL A  38
SER A  40
ASN A  47
ASN A  71
ARG A  73
GLN A  76
ASN A 104
 FMN  A 500 (-4.8A)
FMN  A 500 (-3.1A)
FMN  A 500 ( 3.7A)
FMN  A 500 ( 3.2A)
FMN  A 500 (-4.5A)
FMN  A 500 (-4.2A)
FMN  A 500 (-3.0A)
 0.89A 4kuoA-6gbvA:
23.6		 4kuoA-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUO_A_RBFA500_1
(BLUE-LIGHT
PHOTORECEPTOR)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		10 / 12 VAL A  38
SER A  40
ASN A  47
ASN A  71
CYH A  72
ARG A  73
ASN A 104
ASN A 114
LEU A 116
GLN A 135
 FMN  A 500 (-4.8A)
FMN  A 500 (-3.1A)
FMN  A 500 ( 3.7A)
FMN  A 500 ( 3.2A)
FMN  A 500 (-3.7A)
FMN  A 500 (-4.5A)
FMN  A 500 (-3.0A)
FMN  A 500 (-4.0A)
FMN  A 500 (-4.1A)
FMN  A 500 (-3.8A)
 0.77A 4kuoA-6gbvA:
23.6		 4kuoA-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUO_A_RBFA500_1
(BLUE-LIGHT
PHOTORECEPTOR)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		10 / 12 VAL A  38
SER A  40
ASN A  47
ASN A  71
CYH A  72
LEU A  92
ASN A 104
ASN A 114
LEU A 116
GLN A 135
 FMN  A 500 (-4.8A)
FMN  A 500 (-3.1A)
FMN  A 500 ( 3.7A)
FMN  A 500 ( 3.2A)
FMN  A 500 (-3.7A)
FMN  A 500 (-4.6A)
FMN  A 500 (-3.0A)
FMN  A 500 (-4.0A)
FMN  A 500 (-4.1A)
FMN  A 500 (-3.8A)
 0.57A 4kuoA-6gbvA:
23.6		 4kuoA-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUO_A_RBFA500_1
(BLUE-LIGHT
PHOTORECEPTOR)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		7 / 12 VAL A  38
SER A  40
ASN A  47
ASN A  71
GLN A  76
LEU A  92
ASN A 104
 FMN  A 500 (-4.8A)
FMN  A 500 (-3.1A)
FMN  A 500 ( 3.7A)
FMN  A 500 ( 3.2A)
FMN  A 500 (-4.2A)
FMN  A 500 (-4.6A)
FMN  A 500 (-3.0A)
 0.80A 4kuoA-6gbvA:
23.6		 4kuoA-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUO_A_RBFA500_1
(BLUE-LIGHT
PHOTORECEPTOR)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		6 / 12 VAL A  38
SER A  40
ASN A  47
CYH A  72
LEU A  92
ASN A 104
 FMN  A 500 (-4.8A)
FMN  A 500 (-3.1A)
FMN  A 500 ( 3.7A)
FMN  A 500 (-3.7A)
FMN  A 500 (-4.6A)
FMN  A 500 (-3.0A)
 1.09A 4kuoA-6gbvA:
23.6		 4kuoA-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		5 / 12 ALA A  87
ASN A 104
LEU A 116
GLY A 133
GLN A 135
 None
FMN  A 500 (-3.0A)
FMN  A 500 (-4.1A)
FMN  A 500 (-3.9A)
FMN  A 500 (-3.8A)
 1.12A 4r38A-6gbvA:
18.3		 4r38A-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		6 / 12 ARG A  73
ASN A 104
ASN A 114
LEU A 116
GLY A 133
GLN A 135
 FMN  A 500 (-4.5A)
FMN  A 500 (-3.0A)
FMN  A 500 (-4.0A)
FMN  A 500 (-4.1A)
FMN  A 500 (-3.9A)
FMN  A 500 (-3.8A)
 0.66A 4r38A-6gbvA:
18.3		 4r38A-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		5 / 12 ARG A  73
GLN A  76
ASN A 104
GLY A 133
GLN A 135
 FMN  A 500 (-4.5A)
FMN  A 500 (-4.2A)
FMN  A 500 (-3.0A)
FMN  A 500 (-3.9A)
FMN  A 500 (-3.8A)
 0.97A 4r38A-6gbvA:
18.3		 4r38A-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		6 / 12 CYH A  72
ARG A  73
ASN A 104
LEU A 116
GLY A 133
GLN A 135
 FMN  A 500 (-3.7A)
FMN  A 500 (-4.5A)
FMN  A 500 (-3.0A)
FMN  A 500 (-4.1A)
FMN  A 500 (-3.9A)
FMN  A 500 (-3.8A)
 0.96A 4r38A-6gbvA:
18.3		 4r38A-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		5 / 12 ALA A  87
ASN A 104
LEU A 116
GLY A 133
GLN A 135
 None
FMN  A 500 (-3.0A)
FMN  A 500 (-4.1A)
FMN  A 500 (-3.9A)
FMN  A 500 (-3.8A)
 1.16A 4r38B-6gbvA:
18.4		 4r38B-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		7 / 12 ASN A  71
ARG A  73
ASN A 104
ASN A 114
LEU A 116
GLY A 133
GLN A 135
 FMN  A 500 ( 3.2A)
FMN  A 500 (-4.5A)
FMN  A 500 (-3.0A)
FMN  A 500 (-4.0A)
FMN  A 500 (-4.1A)
FMN  A 500 (-3.9A)
FMN  A 500 (-3.8A)
 0.79A 4r38B-6gbvA:
18.4		 4r38B-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		6 / 12 ASN A  71
ARG A  73
GLN A  76
ASN A 104
GLY A 133
GLN A 135
 FMN  A 500 ( 3.2A)
FMN  A 500 (-4.5A)
FMN  A 500 (-4.2A)
FMN  A 500 (-3.0A)
FMN  A 500 (-3.9A)
FMN  A 500 (-3.8A)
 1.04A 4r38B-6gbvA:
18.4		 4r38B-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		7 / 12 ASN A  71
CYH A  72
ARG A  73
ASN A 104
LEU A 116
GLY A 133
GLN A 135
 FMN  A 500 ( 3.2A)
FMN  A 500 (-3.7A)
FMN  A 500 (-4.5A)
FMN  A 500 (-3.0A)
FMN  A 500 (-4.1A)
FMN  A 500 (-3.9A)
FMN  A 500 (-3.8A)
 0.95A 4r38B-6gbvA:
18.4		 4r38B-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		5 / 12 ALA A  87
ASN A 104
LEU A 116
GLY A 133
GLN A 135
 None
FMN  A 500 (-3.0A)
FMN  A 500 (-4.1A)
FMN  A 500 (-3.9A)
FMN  A 500 (-3.8A)
 1.12A 4r38C-6gbvA:
18.5		 4r38C-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		6 / 12 ARG A  73
ASN A 104
ASN A 114
LEU A 116
GLY A 133
GLN A 135
 FMN  A 500 (-4.5A)
FMN  A 500 (-3.0A)
FMN  A 500 (-4.0A)
FMN  A 500 (-4.1A)
FMN  A 500 (-3.9A)
FMN  A 500 (-3.8A)
 0.67A 4r38C-6gbvA:
18.5		 4r38C-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		5 / 12 ARG A  73
GLN A  76
ASN A 104
GLY A 133
GLN A 135
 FMN  A 500 (-4.5A)
FMN  A 500 (-4.2A)
FMN  A 500 (-3.0A)
FMN  A 500 (-3.9A)
FMN  A 500 (-3.8A)
 0.93A 4r38C-6gbvA:
18.5		 4r38C-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		6 / 12 CYH A  72
ARG A  73
ASN A 104
LEU A 116
GLY A 133
GLN A 135
 FMN  A 500 (-3.7A)
FMN  A 500 (-4.5A)
FMN  A 500 (-3.0A)
FMN  A 500 (-4.1A)
FMN  A 500 (-3.9A)
FMN  A 500 (-3.8A)
 0.96A 4r38C-6gbvA:
18.5		 4r38C-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		5 / 9 ASN A  71
LEU A  75
VAL A  85
ILE A 102
PHE A 131
 FMN  A 500 ( 3.2A)
FMN  A 500 (-4.0A)
FMN  A 500 (-4.3A)
FMN  A 500 ( 4.3A)
FMN  A 500 (-4.8A)
 0.79A 4r38C-6gbvA:
18.5		 4r38C-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		5 / 12 ALA A  87
ASN A 104
LEU A 116
GLY A 133
GLN A 135
 None
FMN  A 500 (-3.0A)
FMN  A 500 (-4.1A)
FMN  A 500 (-3.9A)
FMN  A 500 (-3.8A)
 1.11A 4r38D-6gbvA:
18.5		 4r38D-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		5 / 12 ARG A  73
GLN A  76
ASN A 104
GLY A 133
GLN A 135
 FMN  A 500 (-4.5A)
FMN  A 500 (-4.2A)
FMN  A 500 (-3.0A)
FMN  A 500 (-3.9A)
FMN  A 500 (-3.8A)
 0.93A 4r38D-6gbvA:
18.5		 4r38D-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		7 / 12 CYH A  72
ARG A  73
ASN A 104
ASN A 114
LEU A 116
GLY A 133
GLN A 135
 FMN  A 500 (-3.7A)
FMN  A 500 (-4.5A)
FMN  A 500 (-3.0A)
FMN  A 500 (-4.0A)
FMN  A 500 (-4.1A)
FMN  A 500 (-3.9A)
FMN  A 500 (-3.8A)
 0.93A 4r38D-6gbvA:
18.5		 4r38D-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		5 / 12 CYH A  72
ARG A  73
GLN A  76
ASN A 104
GLN A 135
 FMN  A 500 (-3.7A)
FMN  A 500 (-4.5A)
FMN  A 500 (-4.2A)
FMN  A 500 (-3.0A)
FMN  A 500 (-3.8A)
 1.14A 4r3aA-6gbvA:
14.4		 4r3aA-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		7 / 12 CYH A  72
ARG A  73
ILE A 102
ASN A 104
ASN A 114
LEU A 116
GLN A 135
 FMN  A 500 (-3.7A)
FMN  A 500 (-4.5A)
FMN  A 500 ( 4.3A)
FMN  A 500 (-3.0A)
FMN  A 500 (-4.0A)
FMN  A 500 (-4.1A)
FMN  A 500 (-3.8A)
 0.76A 4r3aA-6gbvA:
14.4		 4r3aA-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		5 / 10 ASN A  71
LEU A  75
GLN A  76
VAL A  85
PHE A 131
 FMN  A 500 ( 3.2A)
FMN  A 500 (-4.0A)
FMN  A 500 (-4.2A)
FMN  A 500 (-4.3A)
FMN  A 500 (-4.8A)
 1.03A 4r3aB-6gbvA:
14.8		 4r3aB-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		8 / 12 CYH A  72
ARG A  73
ILE A 102
ASN A 104
ASN A 114
LEU A 116
GLY A 133
GLN A 135
 FMN  A 500 (-3.7A)
FMN  A 500 (-4.5A)
FMN  A 500 ( 4.3A)
FMN  A 500 (-3.0A)
FMN  A 500 (-4.0A)
FMN  A 500 (-4.1A)
FMN  A 500 (-3.9A)
FMN  A 500 (-3.8A)
 0.65A 4r3aB-6gbvA:
14.8		 4r3aB-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MQT_C_STIC302_1
(DEOXYCYTIDINE KINASE)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		5 / 12 ILE A 121
GLU A  32
VAL A  37
PRO A  48
ARG A 119
 None
 1.42A 5mqtC-6gbvA:
undetectable		 5mqtC-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUO_D_08HD501_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		 6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR
(Dinoroseobacter
shibae) 		4 / 8 ASN A 104
PHE A  74
VAL A  38
SER A  36
 FMN  A 500 (-3.0A)
None
FMN  A 500 (-4.8A)
None
 1.21A 6huoC-6gbvA:
undetectable
6huoD-6gbvA:
undetectable		 6huoC-6gbvA:
undetectable
6huoD-6gbvA:
undetectable