SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6gdr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_A_DVAA6_0
(GRAMICIDIN A)		 6gdr -
(-) 		3 / 3 ALA A 216
VAL A 268
TRP A 267
 None
 0.86A 1grmA-6gdrA:
undetectable		 1grmA-6gdrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_B_DVAB6_0
(GRAMICIDIN A)		 6gdr -
(-) 		3 / 3 ALA A 216
VAL A 268
TRP A 267
 None
 0.86A 1grmB-6gdrA:
undetectable		 1grmB-6gdrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 6gdr -
(-) 		3 / 3 ALA A 216
VAL A 268
TRP A 267
 None
 0.87A 1jo3A-6gdrA:
undetectable		 1jo3A-6gdrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 6gdr -
(-) 		3 / 3 ALA A 216
VAL A 268
TRP A 267
 None
 0.88A 1jo3B-6gdrA:
undetectable		 1jo3B-6gdrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 6gdr -
(-) 		3 / 3 ALA A 216
VAL A 268
TRP A 267
 None
 0.92A 1jo4A-6gdrA:
undetectable		 1jo4A-6gdrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 6gdr -
(-) 		3 / 3 ALA A 216
VAL A 268
TRP A 267
 None
 0.92A 1jo4B-6gdrA:
undetectable		 1jo4B-6gdrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_B_SAMB4001_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 6gdr -
(-) 		5 / 12 GLY A 187
GLY A 189
LEU A 184
LEU A 179
PHE A 283
 None
 1.01A 1zq9B-6gdrA:
undetectable		 1zq9B-6gdrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QWU_A_ADNA501_1
(DNA LIGASE)		 6gdr -
(-) 		5 / 12 LYS A  34
GLU A  73
PHE A 133
VAL A 164
LYS A 209
 None
 0.68A 3qwuA-6gdrA:
9.8		 3qwuA-6gdrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_B_TYLB2198_1
(CREB-BINDING PROTEIN)		 6gdr -
(-) 		4 / 5 VAL A  31
LEU A 169
ILE A  26
VAL A 210
 None
 0.98A 4a9kB-6gdrA:
undetectable		 4a9kB-6gdrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_A_H4BA804_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6gdr -
(-) 		4 / 7 ARG A 129
VAL A  88
TRP A 125
PHE A  61
 None
 1.36A 4jseA-6gdrA:
undetectable
4jseB-6gdrA:
undetectable		 4jseA-6gdrA:
undetectable
4jseB-6gdrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6gdr -
(-) 		4 / 7 TRP A 125
PHE A  61
ARG A 129
VAL A  88
 None
 1.42A 4jseA-6gdrA:
undetectable
4jseB-6gdrA:
undetectable		 4jseA-6gdrA:
undetectable
4jseB-6gdrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DB5_A_CYSA503_0
(CYSTEINE DESULFURASE)		 6gdr -
(-) 		4 / 8 ALA A 162
ASN A 158
LYS A 153
ARG A 129
 None
 1.21A 5db5A-6gdrA:
undetectable
5db5B-6gdrA:
undetectable		 5db5A-6gdrA:
undetectable
5db5B-6gdrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_2
(ADENOSYLHOMOCYSTEINA
SE)		 6gdr -
(-) 		4 / 5 THR A 183
GLU A  33
HIS A 193
LEU A 192
 None
 1.32A 5utuH-6gdrA:
undetectable		 5utuH-6gdrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WEA_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 6gdr -
(-) 		4 / 5 LEU A 190
TYR A  17
LEU A 179
GLU A 176
 None
 1.33A 5weaA-6gdrA:
undetectable		 5weaA-6gdrA:
undetectable